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公开(公告)号:US20220259699A1
公开(公告)日:2022-08-18
申请号:US17736930
申请日:2022-05-04
申请人: W. Davis Lee , Mark R. Amato
发明人: W. Davis Lee , Mark R. Amato
摘要: The invention comprises an apparatus and method of use thereof for generating a rare earth from a rare earth oxide, comprising the steps of: (1) dissociating the rare earth oxide and hydrogen gas in a reaction chamber by inductively heating the reaction chamber to greater than 2000° K to form the associated rare earth and water vapor in a reaction process; (2) driving the reaction process forward by removing the water vapor from the reaction chamber by condensing and freezing the water vapor on a first cold trap surface as water ice, where the reaction comprises: RE2O3+3H2→2RE+3 H2O, where REO is a rare earth oxide and RE comprises a rare earth in the rare earth oxide; and/or (3) monitoring the reaction process by monitoring generation of at least one of the rare earth and the water in a control system designed for continuous/semi-continuous operation.
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2.
公开(公告)号:US11000696B2
公开(公告)日:2021-05-11
申请号:US16601592
申请日:2019-10-15
申请人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
发明人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
摘要: The invention comprises a method and apparatus for scanning charged particles in a cancer therapy system, comprising the steps of: (1) providing a first and second dipole magnet system and a gap, the gap comprising a common gap length, along a path of the charged particles, within both the first and second dipole magnet systems, the gap comprising a progressively increasing x/y-plane cross-section area from an entrance area of the charged particles into the double dipole magnet system to an exit area of the double dipole magnet system, the x/y-plane perpendicular to a z-axis from a center of the entrance area to a center of the exit area; (2) scanning the positively charged particles along a first axis of the x/y-plane using the first dipole magnet system; and (3) scanning the positively charged particles along a second axis of the x/y-plane using the second dipole magnet system.
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公开(公告)号:US10188877B2
公开(公告)日:2019-01-29
申请号:US15402739
申请日:2017-01-10
申请人: W. Davis Lee , Mark R. Amato , Nick Ruebel , Jillian Reno , Susan L. Michaud
发明人: W. Davis Lee , Mark R. Amato , Nick Ruebel , Jillian Reno , Susan L. Michaud
摘要: The invention comprises a fiducial marker—fiducial detector based treatment room position determination/positioning system apparatus and method of use thereof. A set of fiducial markers and fiducial detectors are used to mark/determine relative position of static and/or moveable objects in a treatment room using photons passing from the markers to the detectors. Further, position and orientation of at least one of the objects is calibrated to a reference line, such as a zero-offset beam treatment line passing through an exit nozzle, which yields a relative position of each fiducially marked object in the treatment room. Treatment calculations are subsequently determined using the reference line and/or points thereon. The treatment calculations are optionally and preferably performed without use of an isocenter point, such as a central point about which a treatment room gantry rotates, which eliminates mechanical errors associated with the isocenter point being an isocenter volume in practice.
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公开(公告)号:US20190021684A1
公开(公告)日:2019-01-24
申请号:US16131015
申请日:2018-09-13
申请人: Nick Ruebel , Mark R. Amato , Susan L. Michaud , James P. Bennett , Jillian Reno , W. Davis Lee
发明人: Nick Ruebel , Mark R. Amato , Susan L. Michaud , James P. Bennett , Jillian Reno , W. Davis Lee
摘要: The invention comprises a method and apparatus for treating a tumor, comprising the steps of: (1) a main controller sequentially delivering charged particles from a synchrotron along a first beam transport line, through a nozzle system, and to the tumor according to a current version of the radiation treatment plan; (2) concurrent with the step of delivering, generating an image of the tumor using an imaging system; (3) the main controller automatically generating an updated version of the radiation treatment plan using the image, the updated version of the radiation treatment plan becoming the current version of the radiation treatment plan; and (4) repeating the steps of: delivering grouped bunches of the charged particles, generating an image of the tumor, and automatically generating the updated or current version of the radiation treatment plan with optional intervening doctor approval.
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5.
公开(公告)号:US20180104510A1
公开(公告)日:2018-04-19
申请号:US15847497
申请日:2017-12-19
申请人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
发明人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
CPC分类号: A61N5/10 , A61N5/1043 , A61N5/1081 , A61N2005/1087 , H01J37/08 , H05H13/005 , H05H13/04 , H05H2007/046 , H05H2277/11
摘要: The invention comprises a method and apparatus for scanning charged particles in a cancer therapy system, comprising the steps of: (1) providing a first and second dipole magnet system and a gap, the gap comprising a common gap length, along a path of the charged particles, within both the first and second dipole magnet systems, the gap comprising a progressively increasing x/y-plane cross-section area from an entrance area of the charged particles into the double dipole magnet system to an exit area of the double dipole magnet system, the x/y-plane perpendicular to a z-axis from a center of the entrance area to a center of the exit area; (2) scanning the positively charged particles along a first axis of the x/y-plane using the first dipole magnet system; and (3) scanning the positively charged particles along a second axis of the x/y-plane using the second dipole magnet system.
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6.
公开(公告)号:US20180099156A1
公开(公告)日:2018-04-12
申请号:US15838072
申请日:2017-12-11
申请人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
发明人: Faye Hendley Elgart , Nick Ruebel , Mark R. Amato , Nandish Desai , W. Davis Lee
CPC分类号: A61N5/1043 , A61B6/032 , A61B6/4014 , A61B6/4021 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1039 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1071 , A61N5/1077 , A61N5/1082 , A61N2005/1051 , A61N2005/1052 , A61N2005/1054 , A61N2005/1061 , A61N2005/1074 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/093 , G21K5/04
摘要: The invention comprises a method and apparatus for steering/scanning charged particles, comprising: a double dipole scanning system, comprising: (1) a beam path chamber comprising an entrance side and an exit side, the entrance side comprising a smaller area than the exit side; (2) a first dipole magnet, the first dipole magnet comprising a first coil and a third coil on first opposite sides of the beam path chamber; and (3) a second dipole magnet, the second dipole magnet comprising a second coil and a fourth coil on second opposite sides of the beam path chamber, the beam path chamber further comprising a truncated square/rectangle pyramid shape, the smaller entrance side of the charged particles comprising a top of the truncated pyramid shape, the exit side of the charged particles comprising a larger bottom of the truncated pyramid shape.
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公开(公告)号:US20170203125A1
公开(公告)日:2017-07-20
申请号:US15478927
申请日:2017-04-04
申请人: Mark R. Amato , Susan L. Michaud , James P. Bennett , Jillian Reno , W. Davis Lee , Nick Ruebel
发明人: Mark R. Amato , Susan L. Michaud , James P. Bennett , Jillian Reno , W. Davis Lee , Nick Ruebel
IPC分类号: A61N5/10
CPC分类号: A61N5/1039 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1071 , A61N5/1077 , A61N5/1081 , A61N5/1082 , A61N2005/1051 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要: The invention comprises a method for generating a procedure for treating a tumor of a patient using positively charged particles, comprising the steps of: (1) providing a set of treatment goal specifications; (2) generating tomographic images of the tumor using a first set of groups of the positively charge particles delivered from a synchrotron; and (3) a computer implemented algorithm automatically generating a tumor radiation treatment plan, of the tumor using the positively charged particles, using the set of treatment goal specifications and the tomographic images. Optionally, the method automatically updates the radiation treatment plan upon: a detected movement of the tumor relative to surrounding patient constituents and/or upon detection of a previously unforeseen intervening object in a treatment beam path.
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公开(公告)号:US20170203124A1
公开(公告)日:2017-07-20
申请号:US15474916
申请日:2017-03-30
申请人: Jillian Reno , Mark R. Amato , Susan L. Michaud , James P. Bennett , Nick Ruebel , W. Davis Lee
发明人: Jillian Reno , Mark R. Amato , Susan L. Michaud , James P. Bennett , Nick Ruebel , W. Davis Lee
IPC分类号: A61N5/10
CPC分类号: A61N5/1039 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1077 , A61N5/1081 , A61N5/1082 , A61N2005/1051 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要: The invention comprises a method for treating a tumor of a patient with positively charged particles in a treatment room, comprising the steps of: (1) controlling a cancer therapy treatment system with a main controller, the main controller comprising hardware and software; (2) generating at least one image of the tumor using at least one imaging system controlled by the main controller; (3) using the at least one image and a software coded set of radiation treatment directives, the main controller auto-generating a radiation treatment plan; and (4) the main controller auto-delivering the positively charged particles, via a beam transport system and a nozzle system, from a synchrotron to the tumor according to the radiation treatment plan.
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9.
公开(公告)号:US20170189722A1
公开(公告)日:2017-07-06
申请号:US15459854
申请日:2017-03-15
申请人: Jillian Reno , Susan L. Michaud , Nick Ruebel , Mark R. Amato , W. Davis Lee , James P. Bennett
发明人: Jillian Reno , Susan L. Michaud , Nick Ruebel , Mark R. Amato , W. Davis Lee , James P. Bennett
IPC分类号: A61N5/10
摘要: The invention comprises a method and apparatus for determining a radiation beam treatment path to a tumor, comprising the steps of: (1) delivering charged particles from an accelerator, along a first beam transport path, through an output nozzle, and along a treatment path to the tumor relative to a calibrated reference beam path from the output nozzle toward a patient position and (2) prior to the step of delivering, a main controller verifying an unobstructed linear path of the treatment path using a set of fiducial indicators positioned at least: on a first element physically affixed and co-movable with the output nozzle and on a moveable object in the treatment room. Optionally, voxels of the treatment beam path and potentially obstructing objects are defined in the treatment room using an axis system relative to the calibrated reference beam path and a reference beam point.
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10.
公开(公告)号:US20170128029A1
公开(公告)日:2017-05-11
申请号:US15412885
申请日:2017-01-23
申请人: Scott Penfold , Mark R. Amato , Edward Ivanov , Jillian Reno , Nick Ruebel , Stephen Siedge , Lauri Reichert , Kyle Schmanke , W. Davis Lee , James P. Bennett
发明人: Scott Penfold , Mark R. Amato , Edward Ivanov , Jillian Reno , Nick Ruebel , Stephen Siedge , Lauri Reichert , Kyle Schmanke , W. Davis Lee , James P. Bennett
CPC分类号: A61B6/4417 , A61B6/032 , A61B6/037 , A61B6/4258 , A61B6/4266 , A61B6/50 , A61B6/5205 , A61B6/5235 , A61N5/1037 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1077 , A61N5/1081 , A61N5/1082 , A61N2005/1051 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G01N23/04 , G01N2223/1006 , G01T1/2018 , G21K1/08 , G21K5/04
摘要: The invention comprises an apparatus and method of use thereof for using a single patient position during, optionally simultaneous, X-ray imaging and positively charged particle imaging, where imaging a tumor of a patient using X-rays and positively charged particles comprises the steps of: (1) generating an X-ray image using the X-rays directed from an X-ray source, through the patient, and to an X-ray detector, (2) generating a positively charged particle image: (a) using the positively charged particles directed from an exit nozzle, through the patient, through the X-ray detector, and to a scintillator, the scintillator emitting photons when struck by the positively charged particles and (b) generating the positively charged particle image of the tumor using a photon detector configured to detect the emitted photons, where the X-ray detector maintains a position between said the nozzle and the scintillator during the step of generating a positively charged particle image.
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