公开(公告)号：US11547789B2

公开(公告)日：2023-01-10

申请号：US16646464

申请日：2018-08-21

申请人： KCI Licensing, Inc.

发明人： Christopher Brian Locke ,  Justin Alexander Long ,  Kristine M. Kieswetter

IPC分类号： A61M1/00 ,  A61M35/00 ,  A61F13/02

摘要： An apparatus for treating a tissue site includes a dressing, an oxygen source, a valve, and a negative-pressure source. The dressing is configured to be sealed around the tissue site. The oxygen source is fluidly coupled to the dressing and configured to provide a low flow of oxygen. A first port of the valve is fluidly coupled to the dressing and the valve moves between a closed position preventing flow through the valve and an open position permitting flow through the valve. The negative-pressure source is fluidly coupled to a second port of the valve and provides negative pressure to the second port of the valve at a non-therapeutic level. The valve separates the negative-pressure source from the dressing and selectively opens when a positive pressure is applied on an upstream side of the valve.

公开(公告)号：US11534585B2

公开(公告)日：2022-12-27

申请号：US16594390

申请日：2019-10-07

申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION

发明人： Yang Liu ,  Steven L. Wright

IPC分类号： A61M31/00 ,  A61B5/00 ,  A61K9/00 ,  A61B5/145 ,  F16K99/00 ,  A61M35/00 ,  H01M50/60

摘要： Embodiments of the present invention are directed to a liquid delivery apparatus. A non-limiting example of the apparatus includes a substrate including a cavity formed in a surface of the substrate. The apparatus can also include a membrane disposed on the surface of the substrate covering an opening of the cavity. The apparatus can also include a hydrophobic layer disposed on the membrane. The apparatus can also include a seal disposed between the membrane and the substrate, wherein the seal surrounds the opening of the cavity. The apparatus can also include an electrode layer coupled to the membrane.

公开(公告)号：US20220401431A1

公开(公告)日：2022-12-22

申请号：US17893147

申请日：2022-08-22

申请人： Alexza Pharmaceuticals, Inc.

发明人： Daniel J. MYERS ,  James CASSELLA

IPC分类号： A61K31/465 ,  A61M15/06 ,  A61K9/00 ,  A61K31/60 ,  A61M5/00 ,  A61M11/04 ,  A61M15/00 ,  A61M35/00 ,  A61M37/00 ,  C07D401/04 ,  A24B15/167 ,  A61M31/00 ,  C07C63/08 ,  H05B1/02 ,  C07C65/10

摘要： The present disclosure relates generally to the field of nicotine delivery. The disclosure teaches a nicotine meta-salicylate. More specifically, the disclosure teaches a condensation nicotine aerosol where nicotine meta-salicylate is vaporized. This disclosure relates to aerosol nicotine delivery devices. The delivery devices can be activated by actuation mechanisms to vaporize thin films comprising a nicotine meta-salicylate. More particularly, this disclosure relates to thin films of nicotine salt with meta salicylic acid for the treatment of nicotine craving and for effecting smoking cessation.

公开(公告)号：US20220383496A1

公开(公告)日：2022-12-01

申请号：US17325203

申请日：2021-05-19

申请人： Zerigo Health, Inc.

发明人： Frank D'Amelio

IPC分类号： G06T7/00 ,  G06T7/90 ,  G06T7/60 ,  A61M31/00 ,  A61M35/00 ,  A61N5/06

摘要： A method for evaluating the effectiveness of a skin treatment on a skin feature includes correcting the color of a first image before the skin treatment, correcting the color of a second image after the skin treatment, determining the sizes of the skin feature in the first and second images, and comparing the corrected colors and sizes of the skin feature in the first and second images. In some embodiments, the first and second images include the skin feature and an indicator adjacent to the skin feature, where the indicator has a standard color and a known size.

公开(公告)号：US11511096B2

公开(公告)日：2022-11-29

申请号：US16601641

申请日：2019-10-15

申请人： E INK CORPORATION

发明人： Richard J. Paolini, Jr. ,  Stephen J. Telfer ,  Timothy J. O'Malley ,  Brian D. Bean

IPC分类号： A61M35/00

摘要： An active molecule delivery system whereby active molecules can be released on demand and/or a variety of different active molecules can be delivered from the same system and/or different concentrations of active molecules can be delivered from the same system. The invention is well-suited for delivering pharmaceuticals to patients transdermally. In some embodiments, the system includes two separate reservoirs and a mixing area thereby allowing precursors to be mixed immediately before transdermal delivery.

公开(公告)号：US20220362529A1

公开(公告)日：2022-11-17

申请号：US17743110

申请日：2022-05-12

申请人： CARISMED Corporation

发明人： Serge Castro

IPC分类号： A61M37/00 ,  A61N5/06 ,  A61N1/40 ,  A61N1/32 ,  A61M35/00 ,  A61M1/00

摘要： A skin treatment device includes a control unit and a hand tool. The hand tool includes a body, a wiper head, and a needle roller head. The wiper head includes a rotatable wiper structure including one or more wiper blades. The needle roller head includes needle roller structure. The skin treatment device provides a multi-step process including desincrustation, skin transdermal delivery of topical agents, serums, and the like, microdermabrasion, and fractional micro-channeling application.

公开(公告)号：US11497290B2

公开(公告)日：2022-11-15

申请号：US15768936

申请日：2016-10-17

申请人： Kao Corporation

发明人： Naomi Amari ,  Takehiko Tojo

IPC分类号： A61K8/34 ,  A61Q1/02 ,  A45D34/04 ,  A61K8/81 ,  B05D1/04 ,  A61Q1/00 ,  A61L26/00 ,  A61K8/31 ,  A61Q19/00 ,  A61K8/02 ,  A61K8/35 ,  A61K8/63 ,  A61M35/00 ,  B05B5/16 ,  B05B5/00

摘要： The present invention provides a coating formation method with which adhesion between skin and a coating formed by electrostatic spraying is enhanced. The coating formation method of the present invention includes a liquid agent applying step of applying a liquid agent containing one or more selected from water, polyols and oils that are in a liquid form at 20° C., and an electrostatic spraying step of electrostatically spraying a composition directly on skin to form a coating. The liquid agent applying step and the electrostatic spraying step are performed in this order or in a reversed order. The composition includes a component (a) and a component (b) below: (a) one or more volatile substances selected from the group consisting of water, alcohols, and ketones, and (b) a polymer having a coating formation ability.

公开(公告)号：US20220347400A1

公开(公告)日：2022-11-03

申请号：US17813482

申请日：2022-07-19

申请人： Vaporox, Inc.

发明人： Loren Havener Hutchins, IV ,  Wesley Joseph Weber

IPC分类号： A61M11/00 ,  A61M35/00

摘要： Multistage vaporizers, such as for use in medical treatment systems, as well as related methods are described. In one example, a multistage vaporizer includes a first reservoir configured to hold a liquid and one or more pumping transducers positioned in the first reservoir. The multistage vaporizer also includes a second reservoir and one or more vaporizing transducers positioned in the second reservoir. The one or more pumping transducers positioned in the first reservoir are configured to generate and move droplets of a liquid in the first reservoir to the second reservoir, and the one or more vaporizing transducers positioned in the second reservoir are configured to create a vapor of the liquid in the second reservoir.

公开(公告)号：US11470940B2

公开(公告)日：2022-10-18

申请号：US15721659

申请日：2017-09-29

申请人： L'Oreal

发明人： Joseph W. Grez ,  Carolina Canamaque ,  John Streeter ,  Richard Taylor ,  Mark E. Bartlett ,  Scott P. Mosby ,  Joseph Michael Recco ,  Francis George Tatu ,  Adam Paul Vallee

IPC分类号： A45D24/28 ,  A45D24/26 ,  A45D24/16 ,  A45D24/00 ,  A61M35/00 ,  A45D19/00

摘要： A formula delivery system can be used in conjunction with hair and scalp treatment appliances to supply a hair treatment formulation to the appliance. In one aspect, the formula delivery system delivers hair coloring formulation to the appliance. Formula delivery systems of the present disclosure generally include at least one fluid container configured to retain a volume of formulation for delivery of the formulation to a hair coloring appliance. In this regard, the formula delivery system may be configured to removably couple to an inlet member of the appliance that allows the appliance to draw the formulation from the fluid container for use within the appliance.

公开(公告)号：USRE49230E1

公开(公告)日：2022-10-04

申请号：US16869586

申请日：2020-05-07

申请人： The Procter & Gamble Company

发明人： Thomas Elliot Rabe ,  Faiz Feisal Sherman

IPC分类号： A61M35/00 ,  A61B5/107 ,  A45D34/04 ,  A61B5/00 ,  B41J2/175 ,  G06T7/00 ,  G06T7/90 ,  A45D34/00 ,  A45D44/00

摘要： A cartridge assembly for modifying a treating surface, having a body that defines a reservoir that has a standpipe. The reservoir stores a treatment composition. The body comprises a reservoir wall and a die wall that collectively define a reservoir volume. The standpipe is defined by a standpipe wall that extends into the reservoir from a standpipe base, wherein the standpipe base comprises a portion of the die wall. The standpipe base and the standpipe wall collectively define a standpipe volume. The ratio of the reservoir volume to the standpipe volume is from about 50:1 to about 3:1, preferably from about 20:1 to about 4:1, and more preferably about 8:1. Further, the ratio of the surface area of the die wall to the standpipe base is from about 1.1:1 to about 3:1.