Abstract:
Methods and compositions for preparation of biological samples are disclosed. The methods include a prelysis step and a lysis step to make the cellular DNA available for further processing, amplification or analysis. The prelysis step includes the addition of a prelysis reagent to the cells. The prelysis reagent may include an enzyme to facilitate the disruption of the cells. The lysis step includes the addition of a lysis reagent to at least a portion of the prelysis reagent and cells.
Abstract:
The development of new compositions and new aromatic sulfur acrylate monomers results in improved hardcoat films, and improved optical films that contain the hard coat films. The films provide improved display systems when incorporated thereon. The combination of functionalized zirconia nanoparticles with multifunctional acrylate crosslinkers and high index of refraction aromatic sulfur acrylates, about 1.58 or greater, produces abrasion resistant hard coats that have relatively high refractive indices.
Abstract:
The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Abstract:
External power source, and system and method using such external power source, for an implantable medical device having therapeutic componentry and a secondary coil operatively coupled to the therapeutic componentry. A primary coil is capable of inductively energizing the secondary coil when externally placed in proximity of the secondary coil. A repositionable magnetic core associated with the primary coil is capable of being repositioned by a user of the external power source. An indicator is capable of providing the user with information relative to coupling between the primary coil and the secondary coil as a function of repositioning of the repositionable magnetic core.
Abstract:
External power source, charger, system and method for transcutaneous energy transfer. An implantable medical device has a first housing having operational componentry for providing the therapeutic output. A secondary housing is mechanically coupled to the first housing having a secondary coil operatively coupled to the componentry, the secondary coil capable of receiving energy from the external source. A magnetically shielding material is positioned between the secondary coil and the first housing. An external power source has an external housing. A primary coil carried in the external housing, the primary coil being capable of inductively energizing the secondary coil when the housing is externally placed in proximity of the secondary coil with a first surface of the housing positioned closest to the secondary coil, the first surface of the housing being thermally conductive surface. An energy absorptive material carried within the external housing.
Abstract:
In general, the invention is directed to a patient programmer for an implantable medical device. The patient programmer may include one or more of a variety of features that may enhance performance, support mobility and compactness, or promote patient convenience.
Abstract:
In general, the invention is directed to a patient programmer for an implantable medical device. The patient programmer may include one or more of a variety of features that may enhance performance, support mobility and compactness, or promote patient convenience.
Abstract:
The present invention is directed to an adaptor for measuring an echo return loss in a communication system. The adaptor includes two transformers, each having a primary winding and two secondary windings. The secondary windings are cross-connected to form first and second out of phase circuits. The first circuit includes impedance elements which match an impedance of an external device. When the external device is attached to the second circuit, the first and second circuits are schematically equivalent, albeit out of phase. When an oscillation signal is input to one transformer, the matched impedance and out-of-phase connection of the secondary windings cancel the signal such that only an echo signal is output by the other transformer.