公开(公告)号：US10701258B2

公开(公告)日：2020-06-30

申请号：US16474620

申请日：2018-01-30

申请人： KOWA COMPANY, LTD.

发明人： Tomohisa Azegami

IPC分类号： H04N5/232 ,  H04Q9/00 ,  H04W84/12 ,  H04L5/00

摘要： [Problem] To enable imaging to be performed with appropriate timing.[Solution] In a camera manipulation device 1 according to the present invention, a trigger signal T12 is issued and imaging is begun when a prescribed command is transmitted from a control circuit side to an imaging unit side (see S12). Because the issuance of such trigger signal T12 is not accepted before a character reception start command is issued, it is possible to perform imaging with appropriate timing.

公开(公告)号：US20200167915A1

公开(公告)日：2020-05-28

申请号：US16637216

申请日：2018-08-06

申请人： KOWA COMPANY, LTD.

发明人： Reiko ARITA ,  Katsumi YABUSAKI

IPC分类号： G06T7/00 ,  A61B3/00 ,  A61B5/00

摘要： Provided are a method, a computer program and a device for noninvasively evaluating a state of a tear fluid and a tear fluid amount of a tear meniscus.Included are a binarization step of binarizing a tear meniscus image, obtained by capturing at least a part of a tear meniscus of a subject, using a predetermined threshold value; an extraction step of extracting a high luminance region indicating a tear meniscus part from the binarized image; and an evaluation step of evaluating a tear fluid state on the basis of the high luminance region.

公开(公告)号：US20200157712A1

公开(公告)日：2020-05-21

申请号：US16631349

申请日：2018-08-01

申请人： KOWA COMPANY, LTD.

发明人： Toshitada SUEOKA

IPC分类号： D03D15/08 ,  D02G3/32 ,  D06C9/00 ,  D02G3/34

摘要： Provided are: a cloth including thermoplastic synthetic staple fibers, especially a woven or knitted fabric in which occurrence of pilling is suppressed and a reduction of the strength or deterioration of the texture of the cloth is suppressed; and a method for manufacturing the cloth. An anti-pilling cloth including thermoplastic synthetic staple fibers, wherein the anti-pilling cloth is characterized by having, on the surface of at least one side of the cloth, melt balls at ends of the staple fibers and polishing traces of melt balls at fluff tip ends of the staple fibers; and a method for manufacturing the anti-pilling cloth.

公开(公告)号：US20200154995A1

公开(公告)日：2020-05-21

申请号：US16627683

申请日：2018-07-03

申请人： KOWA COMPANY, LTD.

发明人： Katsumi YABUSAKI

IPC分类号： A61B3/10 ,  A61B3/14 ,  G06T7/00

摘要： A method, a computer program and a device for evaluating a tear fluid layer non-invasively. The method, computer program, and device include a step of detecting a time when color information in a predetermined region in a tear fluid layer interference fringe image changes by a threshold value or more as an eyelid opening time, a step of extracting an image at the time when the predetermined time has passed from the eyelid opening time as an extracted image from the tear fluid interference fringe images, a determination value calculation step of calculating a determination value from the color information in a pixel in a local region by scanning a predetermined target region, a step of detecting a corresponding pixel by comparing the calculated determination value and a threshold value, and an evaluation step of evaluating tear fluid layer breakdown by comparing the detected pixel and a threshold value.

公开(公告)号：US20200151909A1

公开(公告)日：2020-05-14

申请号：US16609669

申请日：2018-04-27

申请人： KOWA COMPANY, LTD.

发明人： Katsumi YABUSAKI

IPC分类号： G06T7/90

摘要： Provided are an analysis evaluation method and device, and a computer program for the state of a subject surface in a still image. The method includes: a step of acquiring color information of each pixel in a predetermined region in a still image, a step of calculating a numerical value indicating a diversity of color from the acquired color information, a step of calculating an average value of the color information, and a step of calculating a coefficient of variation on the basis of the calculated numerical value indicating the diversity of color and the calculated average value of the color information. Herein, the coefficient of variation is used as an index for evaluating the surface state of an object.

公开(公告)号：US20200147051A1

公开(公告)日：2020-05-14

申请号：US16726857

申请日：2019-12-25

申请人： Kowa Company, Ltd.

发明人： Ryu Oshima ,  Kazuhito Suehira ,  Gary Gordon

IPC分类号： A61K31/423 ,  A61P3/06

摘要： The present invention relates to pharmacological interventions with pemafibrate for moderate or severe hypertriglyceridemia.

公开(公告)号：US20200022960A1

公开(公告)日：2020-01-23

申请号：US16477416

申请日：2018-01-11

申请人： Kowa Company, Ltd.

发明人： Yusuke Sasaki ,  Masato Asahiyama ,  Toshiya Tanaka

IPC分类号： A61K31/423 ,  A61P1/16

摘要： The present invention addresses the problem of providing a medicinal composition and a drug combination by which nonalcoholic fatty liver disease and nonalcoholic steatohepatitis can be prevented and/or treated. The present invention provides a combination of a peroxisome proliferator-activated receptor (PPAR) α agonist with a sodium glucose cotransporter 2 (SGLT2) inhibitor, which is to be used for preventing and/or treating nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.

公开(公告)号：USD863060S1

公开(公告)日：2019-10-15

申请号：US29596298

申请日：2017-03-07

申请人： KOWA COMPANY, LTD.

设计人： Haruyasu Abe ,  Masato Seki

公开(公告)号：US20190282139A1

公开(公告)日：2019-09-19

申请号：US16345107

申请日：2017-11-02

申请人： Kowa Company, Ltd.

发明人： Takaharu ASANO ,  Katsumi YABUSAKI

IPC分类号： A61B5/145 ,  A61B5/1455

摘要： Provided are an in-blood component measurement method, an in-blood component measurement device, and an in-blood component measurement program, enabling more accurate measurement of a proportion of glycohemoglobin in the total hemoglobin concentration in blood. The in-blood component measurement method is designed to have a constitution including the steps of irradiating, with near-infrared light, blood that is a target to be measured for a proportion of glycohemoglobin in the total hemoglobin concentration in blood, receiving transmitted light of the near-infrared light passing through the blood, measuring an absorption spectrum of the blood on the basis of the transmitted light received, and calculating the proportion for the blood that is the target of measurement by comparing absorbance at a first wavelength range including 1450 nm in the measured absorption spectrum to absorbance at the first wavelength range in the absorption spectrum of blood in which the proportion is already known.

公开(公告)号：US20190167645A1

公开(公告)日：2019-06-06

申请号：US16272050

申请日：2019-02-11

申请人： KOWA COMPANY, LTD.

发明人： Toshiaki Takizawa ,  Yasunobu Yoshinaka

IPC分类号： A61K31/423 ,  A61K45/06 ,  A61K31/397

摘要： The present invention addresses the problem of providing a pharmaceutical combination composition and drug combinations for the prevention and/or treatment of dyslipidemic conditions such as atherosclerosis, hypercholesterolemia, low HDL blood disease in mammals including humans. A pharmaceutical composition for the prevention and/or treatment of dyslipidemia, etc. which comprises (a) a compound represented by the general formula (1) (in the formula, each symbol is the same as defined in the specification) or a salt thereof or a solvate thereof and (b) a cholesterol absorption inhibitor.