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公开(公告)号：US20230025493A1
公开(公告)日：2023-01-26
申请号：US17788949
申请日：2020-12-23
Applicant: Kowa Company, Ltd.
Inventor： Reiko ARITA , Katsumi YABUSAKI , Miyako SUZUKI
Abstract: An ophthalmic image of an evaluation target is acquired, a plurality of subsection images is extracted from the ophthalmic image, a state of a subject's eye is predicted for each of the subsection images based on a learned model in which learning has been performed in advance regarding extracting a plurality of subsection images from an ophthalmic image for learning, and predicting a state of a subject's eye for the each of subsection image by machine learning using correct answer data related to a state of each subsection image, and the subsection image is extracted from the ophthalmic image so as to have an image size corresponding to a state of a subject's eye of an evaluation target.
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公开(公告)号：US20200074627A1
公开(公告)日：2020-03-05
申请号：US16609649
申请日：2018-04-27
Inventor： Norihiko YOKOI , Katsumi YABUSAKI
Abstract: A method and device for evaluating the dynamics of a tear fluid layer to objectively and accurately evaluate breakdown of the tear fluid layer, which is a core mechanism of dry eye, are provided. The method includes a step of acquiring color information of each pixel in a predetermined region of a tear fluid layer interference fringe image, which is a moving image or a plurality of static images, a step of calculating a numerical value indicating the diversity of color from the acquired color information, a step of calculating the average value of the color information, and a step of calculating a coefficient of variation on the basis of the calculated numerical value indicating the diversity of color and the calculated average value of the color information. The coefficient of variation is used as an index for evaluating the dynamics of the tear fluid layer.
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3.发明公开公开(公告)号：US20230210369A1
公开(公告)日：2023-07-06
申请号：US18008486
申请日：2021-06-22
Applicant: KOWA COMPANY, LTD.
Inventor： Yuka SUGIURA , Katsumi YABUSAKI , Takao SHINOHARA
Abstract: The method for estimating the fluid state of a liquid of the present invention includes a step (a) of applying heat to the liquid, a step (b) of acquiring a temperature distribution of the liquid to which the heat is applied, and a step (c) of estimating the fluid state of the liquid based on the acquired temperature distribution. The system for estimating the fluid state of a liquid of the present invention includes a heating means (1) that applies heat to the liquid, a temperature distribution acquisition means (2) that acquires a temperature distribution of the liquid to which the heat is applied, and an estimation means (3) that estimates the fluid state of the liquid based on the acquired temperature distribution. According to such method and system for estimating the fluid state of a liquid, the flow of the liquid can be estimated non-invasively.
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公开(公告)号：US20230171369A1
公开(公告)日：2023-06-01
申请号：US18002429
申请日：2021-06-24
Applicant: Kowa Company, Ltd.
Inventor： Katsumi YABUSAKI , Takao SHINOHARA
CPC classification number: H04N5/2624 , G06T7/20 , G06T7/70 , G06T7/90 , G06T2207/10024 , G06T2207/20212 , G06T2207/20081 , G06T2207/20084 , G06T2207/10016 , G06T2207/10072
Abstract: An example apparatus comprising an image acquisition unit configured to acquire a plurality of images having temporal or spatial continuity; a channel assignment unit configured to assign a channel different from each other to at least a part of gradation information on a color and/or gradation information on brightness that can be acquired from each image of the plurality of images based on a predetermined rule; a composite image generation unit configured to generate one composite image in which gradation information on at least a part of each image can be identified by the channel by extracting and combining gradation information to which the channel is assigned from each of the plurality of images; and an inference unit configured to analyze the composite image and to infer the plurality of images.
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公开(公告)号：US20200367743A1
公开(公告)日：2020-11-26
申请号：US16637210
申请日：2018-08-09
Inventor： Norihiko YOKOI , Yuka SUGIURA , Katsumi YABUSAKI
Abstract: A method for dynamically evaluating a tear fluid layer using an interference fringe image of the tear fluid layer composed of a plurality of consecutive frames, and includes: an image creation step of creating at least one break detection image of a first break detection image, a second break detection image, a third break detection image, and a fourth break detection image, which are images for detecting a breaking site of the tear fluid layer; a determination step of determining whether the break detection image created by the image creation step corresponds to a predetermined breakup pattern; a tally step of tallying the determination results determined by the determination step; and an evaluation step of evaluating, on the basis of a tallied result by the tally step, a breakup pattern of the interference fringe image of the tear fluid layer.
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Patent Agency Ranking
公开(公告)号：US20220265170A1
公开(公告)日：2022-08-25
申请号：US17596804
申请日：2020-06-24
Applicant: KOWA COMPANY, LTD.
Inventor： Katsumi YABUSAKI , Nakahiro KATO , Miyako SUZUKI
IPC: A61B5/1455 , A61B5/00 , A61B5/145
Abstract: An object of the present invention is to provide a technique that can improve the measurement accuracy of the blood component concentration. A blood component measurement system emits light to a measurement site of a living body while the measurement site is compressed, and calculates a concentration of a predetermined blood component based on a pulse wave signal acquired based on light received from the measurement site. A blood component measurement system includes a processing unit that performs a process of analyzing the pulse wave signal and determining a pressure condition of the measurement site; and a calculation unit that calculates a concentration of the blood component using the pulse wave signal in a period in which the pressure condition is determined.
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公开(公告)号：US20210212561A1
公开(公告)日：2021-07-15
申请号：US16976375
申请日：2019-03-01
Applicant: KOWA COMPANY, LTD.
Inventor： Reiko ARITA , Katsumi YABUSAKI
Abstract: In classifying images by machine learning, provided are an image classification method, device, and program for classifying the image from which the feature difference is hardly detected, in particular, classifying the interference fringe image of tear fluid layer by the dry eye types. The method includes a step of acquiring a feature value from an interference fringe image of tear fluid layer for learning, a step of constructing a model for classifying an image from the feature value acquired from the interference fringe image of tear fluid layer for learning, a step of acquiring the feature value from an interference fringe image of tear fluid layer for testing, and a step of performing classification processing for classifying the interference fringe image of tear fluid layer for testing by types of dry eye using the model and the feature value acquired from the interference fringe image of tear fluid layer.
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公开(公告)号：US20210042885A1
公开(公告)日：2021-02-11
申请号：US16967784
申请日：2019-02-07
Applicant: KOWA COMPANY, LTD.
Inventor： Katsumi YABUSAKI
Abstract: The image processing device (20) according to the present invention includes an alignment means (31) that arranges a pixel of interest and a plurality of adjacent pixels located around the pixel of interest in order of respective magnitudes of luminance values, a determination means (32) that determines whether the pixel of interest is within a predetermined range intermediate in the pixel of interest and the plurality of adjacent pixels sorted by the alignment means (31), and a substitution means (33) that, when the pixel of interest is not within the predetermined range, substitutes the luminance value of the pixel of interest on the basis of the luminance value of a pixel within the predetermined range.
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公开(公告)号：US20200315446A1
公开(公告)日：2020-10-08
申请号：US16306398
申请日：2017-05-29
Applicant: KOWA COMPANY, LTD.
Inventor： Katsumi YABUSAKI
Abstract: Provided are a method and a device for evaluating a tear fluid to objectively evaluate and determine the severity of dry eye or the like. Color information is acquired in a predetermined region of a tear fluid interference fringe image, a numerical value representing a color diversity is calculated from the color information acquired, and the numerical value representing the color diversity thus calculated is used as an index for evaluating a tear fluid state.
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公开(公告)号：US20200167915A1
公开(公告)日：2020-05-28
申请号：US16637216
申请日：2018-08-06
Applicant: KOWA COMPANY, LTD.
Inventor： Reiko ARITA , Katsumi YABUSAKI
Abstract: Provided are a method, a computer program and a device for noninvasively evaluating a state of a tear fluid and a tear fluid amount of a tear meniscus.Included are a binarization step of binarizing a tear meniscus image, obtained by capturing at least a part of a tear meniscus of a subject, using a predetermined threshold value; an extraction step of extracting a high luminance region indicating a tear meniscus part from the binarized image; and an evaluation step of evaluating a tear fluid state on the basis of the high luminance region.
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