URETERAL STENTS AND METHODS FOR USING THE SAME

    公开(公告)号:US20230125981A1

    公开(公告)日:2023-04-27

    申请号:US17906243

    申请日:2021-03-18

    Abstract: Embodiments pertain to ureteral stents for treatment of partial or full ureteral occlusion by bridging one or more ureteral occlusions, where each stent includes a tubular portion, a first spout portion and a second spout portion. The stent may have one or more tapered edges by having the smallest diameter of the first and/or the second spout portion smaller than the largest diameter of the tubular portion, and/or be of an overall length allowing the ureteral stent to be completely located within a patient's ureter once deployed therein.

    Methods of diagnosing malignant diseases

    公开(公告)号:US11519914B2

    公开(公告)日:2022-12-06

    申请号:US16480342

    申请日:2018-01-25

    Inventor: Esther Rabizadeh

    Abstract: A method for diagnosing a malignant proliferative disease or disorder in a subject, and/or for following up, monitoring or prognosticating the therapy of a malignant proliferative disease or disorder in a subject is disclosed. The method is based on measurement of platelet-mediated fibrinogen-like protein 2 (FGL2) activity in a sample essentially comprising platelets obtained from the subject. In accordance with the disclosed method, platelet-mediated FGL2 activity level higher than control is indicative of the presence of a malignant proliferative disease or disorder in a subject.

    COMPOSITIONS AND METHODS FOR TREATMENT OF OCULAR DISEASES

    公开(公告)号:US20210206834A1

    公开(公告)日:2021-07-08

    申请号:US17154864

    申请日:2021-01-21

    Abstract: Methods for treating and/or preventing choroidal neovascularization (CNV) or retinal leakage associated with CNV are disclosed, comprising the use of activated protein C (APC) and/or an APC variant. A disclosed method may be applied in the treatment or prevention of ocular diseases, disorders or conditions that are caused directly by CVN, feature development of CNV as a secondary stage or a complication thereof, and/or feature CNV as a synchronous or asynchronous sequela thereof. An exemplary disease treatable by a disclosed method is neovascular age-related macular degeneration (nAMD).

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