公开(公告)号：US12201664B2

公开(公告)日：2025-01-21

申请号：US17059595

申请日：2019-05-28

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyun Ok Yang ,  Keon Wook Kang ,  Sung Won Kwon ,  Jeong Hill Park ,  Hocheol Kim ,  Myung Sook Oh ,  Dae Sik Jang ,  Doheon Lee ,  Hak Cheol Kwon ,  Byung Hwa Jung

IPC: A61K36/54 ,  A61K36/268 ,  A61K36/346 ,  A23K10/30 ,  A23L33/105

Abstract: The present invention relates to a pharmaceutical composition for prevention or treatment of an allergic disease comprising a mixed extract of two or more selected from the group consisting of Asiasarum root, Platycodon root, and Cinnamomi ramulus as an active ingredient; a method for prevention or treatment of an allergic disease using the pharmaceutical composition; and a health functional food and a feed composition for improvement of an allergic disease. The composition and method of the invention can specifically inhibit the differentiation of Th2 cells and thus can be effectively used as a composition for prevention or treatment of an allergic disease.

公开(公告)号：US12194511B2

公开(公告)日：2025-01-14

申请号：US17389129

申请日：2021-07-29

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  IUCF-HYU (Industry-University Cooperation Foundation Hanyang University) ,  KYONGGI UNIVERSITY INDUSTRY & ACADEMIA COOPERATION FOUNDATION

Inventor： Jongwon Kim ,  Sungkeun Yoo ,  Jooyoung Hong ,  Taewon Seo ,  Hwa Soo Kim ,  Myoungjae Seo ,  Joohyun Oh ,  Jiseok Lee ,  Garam Park ,  Youngjoo Lee ,  Dupyo Yoon ,  Hobyeong Chae

IPC: B66D1/74 ,  B08B3/02 ,  B25J9/00 ,  B25J9/10 ,  B62D57/04 ,  F16M13/02

Abstract: The present disclosure relates to a climbing robot platform. The climbing robot platform is a climbing robot platform of a building facade cleaning robot, and includes a body, a lifting device installed in the body, moving up by winding a rope and moving down by unwinding the rope, and a feeding device installed in the body to feed the rope by adjusting a feed point of the rope.

公开(公告)号：US20250005341A1

公开(公告)日：2025-01-02

申请号：US18654940

申请日：2024-05-03

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Sangbum KIM ,  Sung Min LEE ,  Hoonroe LEE ,  Hyunin MOON

IPC: G06N3/049 ,  G06N3/084

Abstract: A computing device and an operating method of the computing device based on a spiking neural network (SNN) are disclosed. The computing device includes a pulse generator configured to generate a pulse corresponding to an input spike signal; an SNN including layers of spiking neurons each generating an output spike signal by applying the pulse to a neuron model; and a loss circuit module configured to calculate a loss value based on a potential value accumulated by the output spike signal generated for each of the layers and backpropagate the loss value to the SNN.

公开(公告)号：US20250000877A1

公开(公告)日：2025-01-02

申请号：US18708357

申请日：2022-10-28

Applicant: SHAPERON INC. ,  SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Seung Yong SEONG

IPC: A61K31/575 ,  A61P31/16

Abstract: The present invention relates to a composition for preventing or treating virus infection diseases containing taurodeoxycholic acid or a pharmaceutically acceptable salt thereof as an active ingredient. Specifically, inflammatory cells and inflammatory cytokines were found to decrease in the lungs of an influenza virus-infected animal model to which taurodeoxycholic acid or a pharmaceutically acceptable salt thereof was administered as an inflammasome inhibitor, and thus the inflammasome inhibitor containing taurodeoxycholic acid or a pharmaceutically acceptable salt thereof can be used as an active ingredient in the composition for preventing or treating virus infection diseases.

公开(公告)号：US12173444B2

公开(公告)日：2024-12-24

申请号：US17912411

申请日：2021-03-16

Applicant: LG Electronics Inc. ,  Seoul National University R&DB Foundation

Inventor： Taewoong Kong ,  Chaseung Jun ,  Sangwook Hong ,  Seungki Sul ,  Joohyun Lee ,  Hwigon Kim

IPC: D06F34/14 ,  D06F23/02 ,  D06F37/06 ,  D06F37/26 ,  D06F39/04 ,  F26B3/20 ,  G01K7/36 ,  H01F7/02 ,  H01F7/20 ,  H05B6/10

Abstract: Disclosed is a clothes treatment apparatus. The clothes treatment apparatus of the present disclosure may comprise: a cabinet; a drum rotatably provided in the cabinet; an induction heater which is disposed outside the drum and heats the drum; a magnet which is fixed to the drum and of which a residual magnetic flux density changes depending on temperature; and a coil fixed to the outside of the drum and disposed at a position overlapping the magnet in the longitudinal direction of the central axis of rotation of the drum.

公开(公告)号：US20240417733A1

公开(公告)日：2024-12-19

申请号：US18744136

申请日：2024-06-14

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION ,  Korea University Research and Business Foundation ,  KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY ,  Korea National Institute of Health

Inventor： Daehyun BAEK ,  Hee Ryung CHANG ,  Jeong-Sun YANG ,  Hansaem LEE ,  Man-Seong PARK ,  Heedo PARK ,  Yoon Ki KIM ,  Jeeyoon CHANG ,  Joori PARK ,  Joo-Yeon LEE ,  Kyung-Chang KIM

IPC: C12N15/113 ,  A61P31/14

Abstract: The present disclosure relates to a TIS-L targeting antisense oligonucleotide that inhibits the viral replication of SARS-COV-2 and antiviral use thereof. Since the TIS-L targeting antisense oligonucleotide according to the present disclosure has a simple structure, it is easy to mass produce, and as it exhibits antiviral efficacy of 90% or more even at low doses against the original strain and various modified strains of the virus, it can be advantageously utilized in the development of COVID-19 treatment.

公开(公告)号：US20240405083A1

公开(公告)日：2024-12-05

申请号：US18696151

申请日：2023-06-08

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Soo Yeon LEE ,  Jin Kyu LEE

IPC: H01L29/417 ,  H01L29/66 ,  H01L29/786

Abstract: The present invention relates to a high-mobility driving element and a method for manufacturing same, the high-mobility driving element comprising: a substrate; an insulating film disposed on the substrate; a channel layer disposed on at least a partial region of the insulating film and including a metal oxide; a source electrode and a drain electrode connected to the channel layer and disposed on the insulating film and either side of the channel layer to face each other; and a protective layer covering all of the channel layer, the source electrode, and the drain electrode, wherein the channel layer comprises a plurality of fluorinated regions in at least a partial region between the source electrode and the drain electrode.

公开(公告)号：US20240397699A1

公开(公告)日：2024-11-28

申请号：US18570810

申请日：2023-10-17

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Cheol Seong Hwang ,  Seo Young Jang ,  Han Chul Lee

IPC: H10B12/00

Abstract: The present disclosure discloses a capacitorless three-dimensional stacked DRAM device including a plurality of memory cell structures spaced apart from each other in horizontal and vertical directions, each of the plurality of memory cell structures including a horizontal read transistor structure and a horizontal write transistor structure, a plurality of write bit lines connected to the plurality of write transistor structures of the plurality of memory cell structures and extending in the horizontal direction, a plurality of read bit lines connected to the plurality of read transistor structures of the plurality of memory cell structures and extending in the horizontal direction, a plurality of write word lines connected to the plurality of write transistor structures and extending in the vertical direction, and a plurality of read word lines connected to the plurality of read transistor structures and extending in the vertical direction.

公开(公告)号：US20240394534A1

公开(公告)日：2024-11-28

申请号：US18795315

申请日：2024-08-06

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Dongsuk JEON ,  Sun Woo LEE

IPC: G06N3/08

Abstract: Artificial neural network calculation method and device based on parameter quantization using hysteresis are proposed to reduce a size of an artificial neural network. The artificial neural network calculation method may comprise: determining a parameter gradient of a parameter based on a first quantization parameter value of the parameter of the artificial neural network; determining a second original parameter value of the parameter based on a first original parameter value associated with the parameter gradient and the first quantization parameter value; and determining a second quantization parameter value associated with the second original parameter value based on a result of comparing the first quantization parameter value with the second original parameter value. By applying hysteresis to parameter quantization, variability may be reduced, each parameter may be trained more stably, and the performance of a quantized model is improved.

公开(公告)号：US20240394449A1

公开(公告)日：2024-11-28

申请号：US18795368

申请日：2024-08-06

Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Dongsuk JEON ,  Ji Woo HONG

IPC: G06F30/33

Abstract: Proposed is a circuit design method and device that automatically designs circuits by generating candidate circuit structures and optimizing transistor sizes. According to the circuit design method and device, design time and cost are reduced, and circuit performance is improved. The circuit design method may comprise: generating, by a processor, a candidate circuit structure by executing a genetic algorithm based on a gene and associated with a circuit topology graph; and optimizing, by the processor, a transistor size of the candidate circuit structure by executing a reinforcement learning algorithm based on analysis of multiple process corners.