-
公开(公告)号：US20070048299A1
公开(公告)日：2007-03-01
申请号：US11155906
申请日：2005-06-17
申请人： Aya Jakobovits , Pia Challita-Eid , Mary Faris , Wangmao Ge , Rene Hubert , Karen Morrison , Robert Morrison , Arthur Raitano , Daniel Afar
发明人： Aya Jakobovits , Pia Challita-Eid , Mary Faris , Wangmao Ge , Rene Hubert , Karen Morrison , Robert Morrison , Arthur Raitano , Daniel Afar
IPC分类号： A61K39/395 , A61K48/00 , C12N15/861
CPC分类号： C07K14/47 , A61K47/646 , A61K47/6851 , A61K47/6901 , A61K51/1045
摘要： Novel genes designated and set forth in FIG. 2 and their respective encoded proteins, and variants thereof, are described wherein a gene of the invention exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers such as those listed in Table I. Consequently, of gene products of a gene of FIG. 2 provide diagnostic, prognostic, prophylactic and/or therapeutic targets for cancer. A gene of FIG. 2 or fragment thereof, its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with a gene product of FIG. 2 can be used in active or passive immunization.
-
72.发明申请Nucleic acid and corresponding protein entitled 213P1F11 useful in treatment and detection of cancer 失效核酸和相应的蛋白质213P1F11可用于治疗和检测癌症公开(公告)号：US20070037745A1
公开(公告)日：2007-02-15
申请号：US11090545
申请日：2005-03-25
申请人： Pia Challita-Eid , Arthur Raitano , Mary Faris , Rene Hubert , Robert Morrison , Wangmao Ge , Aya Jakobovits
发明人： Pia Challita-Eid , Arthur Raitano , Mary Faris , Rene Hubert , Robert Morrison , Wangmao Ge , Aya Jakobovits
IPC分类号： A01K67/00 , A61K39/395 , C12N5/06 , C07K14/82 , C07K16/18
CPC分类号： C07K14/82 , A01K2217/05 , A01K2267/0331
摘要： A novel gene (designated 213P1F11) and its encoded protein, and variants thereof, are described wherein 213P1F11 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 213P1F11 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 213P1F11 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 213P1F11 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为213P1F11）及其编码的蛋白及其变体，其中213P1F11在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，213P1F11提供诊断，预后， 癌症的预防和/或治疗靶标。 213P1F11基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与213P1F11反应的抗体或T细胞可用于主动或被动免疫。
-
73.发明申请Nucleic acid and corresponding protein entitled 238P1B2 useful in treatment and detection of cancer 失效核酸和相应的蛋白质238P1B2可用于治疗和检测癌症公开(公告)号：US20070015704A1
公开(公告)日：2007-01-18
申请号：US11483302
申请日：2006-07-06
申请人： Arthur Raitano , Pia Challita-Eid , Mary Faris , Rene Hubert , Robert Morrison , Wangmao Ge , Aya Jakobovits
发明人： Arthur Raitano , Pia Challita-Eid , Mary Faris , Rene Hubert , Robert Morrison , Wangmao Ge , Aya Jakobovits
IPC分类号： A61K38/17
CPC分类号： C07K16/30 , A61K39/395 , A61K2039/505 , C07K14/47 , C07K2317/34 , A61K2300/00
摘要： A novel gene (designated 238P1B2) and its encoded protein, and variants thereof, are described wherein 238P1B2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 238P1B2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 238P1B2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 238P1B2 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（命名为238P1B2）及其编码的蛋白及其变体，其中238P1B2在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，238P1B2提供诊断，预后， 癌症的预防和/或治疗靶标。 238P1B2基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与238P1B2反应的抗体或T细胞可用于主动或被动免疫。
-
公开(公告)号：US20050208039A1
公开(公告)日：2005-09-22
申请号：US10776773
申请日：2004-02-10
申请人： Aya Jakobovits , Robert Morrison , Arthur Raitano , Pia Challita-Eid , Juan Perez-Villar , Karen Morrison , Mary Faris , Wangmao Ge , Jean Gudas , Steven Kanner
发明人： Aya Jakobovits , Robert Morrison , Arthur Raitano , Pia Challita-Eid , Juan Perez-Villar , Karen Morrison , Mary Faris , Wangmao Ge , Jean Gudas , Steven Kanner
CPC分类号： C07K16/18 , A61K38/00 , A61K47/646 , A61K47/6813 , A61K51/1093 , C07K14/47 , C07K16/30 , C07K16/3038 , C07K2317/54 , C07K2317/55 , C07K2317/622 , G01N33/57484 , Y10T436/25
摘要： A novel gene (designated 158P1D7) and its encoded protein are described. While 158P1D7 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 158P1D7 provides a diagnostic and/or therapeutic target for cancers. The 158P1D7 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.
-
75.发明申请Nucleic acids and corresponding proteins entitled 158P3D2 useful in treatment and detection of cancer 失效题为158P3D2的核酸和相应的蛋白质可用于治疗和检测癌症公开(公告)号：US20050191312A1
公开(公告)日：2005-09-01
申请号：US10994106
申请日：2004-11-19
申请人： Arthur Raitano , Aya Jakobovits , Pia Challita-Eid , Steven Kanner , Wangmao Ge , Juan Perez-Villar , Robert Morrison
发明人： Arthur Raitano , Aya Jakobovits , Pia Challita-Eid , Steven Kanner , Wangmao Ge , Juan Perez-Villar , Robert Morrison
CPC分类号： C07K14/4748 , A61K39/00 , C07K16/30
摘要： A novel gene 158P3D2 and its encoded protein, and variants thereof, are described wherein 158P3D2 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 158P3D2 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 158P3D2 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 158P3D2 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因158P3D2及其编码的蛋白及其变体，其中158P3D2在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，158P3D2提供诊断，预后，预防和/ 或癌症的治疗靶标。 158P3D2基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与158P3D2反应的抗体或T细胞可用于主动或被动免疫。
-
公开(公告)号：US08236510B2
公开(公告)日：2012-08-07
申请号：US12842971
申请日：2010-07-23
申请人： Aya Jakobovits , Mary Faris , Arthur B. Raitano , Robert Kendall Morrison , Douglas Saffran , Wangmao Ge , Pia M. Challita-Eid
发明人： Aya Jakobovits , Mary Faris , Arthur B. Raitano , Robert Kendall Morrison , Douglas Saffran , Wangmao Ge , Pia M. Challita-Eid
IPC分类号： G01N33/53
CPC分类号： G01N33/68 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K2039/505 , A61K2039/53 , C07K14/47 , C07K14/705 , C07K16/28 , C07K2317/34 , G01N33/5017 , G01N33/57434
摘要： A novel gene (designated 101P3A11 or PHOR-1) and its encoded protein, and variants thereof, are described wherein 101P3A11 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 101P3A11 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 101P3A11 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 101P3A11 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为101P3A11或PHOR-1）及其编码蛋白及其变体，其中101P3A11在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，101P3A11提供 诊断，预后，预防和/或治疗靶标。 101P3A11基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与101P3A11反应的抗体或T细胞可用于主动或被动免疫。
-
77.发明授权Nucleic acid and corresponding protein entitled 85P1B3 useful in treatment and detection of cancer 失效核酸和相应的标题为85P1B3的蛋白质可用于治疗和检测癌症公开(公告)号：US08173381B2
公开(公告)日：2012-05-08
申请号：US12359203
申请日：2009-01-23
申请人： Arthur B. Raitano , Mary Faris , Rene S. Hubert , Daniel Afar , Wangmao Ge , Pia M. Challita-Eid , Aya Jakobovits
发明人： Arthur B. Raitano , Mary Faris , Rene S. Hubert , Daniel Afar , Wangmao Ge , Pia M. Challita-Eid , Aya Jakobovits
IPC分类号： G01N33/574
CPC分类号： C07K14/47
摘要： A novel gene (designated 85P1B3) and its encoded protein are described. While 85P1B3 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 85P1B3 provides a diagnostic and/or therapeutic target for cancers. The 85P1B3 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.
摘要翻译： 描述了一种新型基因（命名为85P1B3）及其编码的蛋白质。 虽然85P1B3在正常成人组织中表现出组织特异性表达，但是在多种癌症中异常表达，如表1所示。因此，85P1B3为癌症提供了诊断和/或治疗靶点。 85P1B3基因或其片段或其编码的蛋白质或其片段可用于引发免疫应答。
-
78.发明申请NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 121P1F1 USEFUL IN TREATMENT AND DETECTION OF CANCER 审中-公开核酸和相关蛋白121P1F1可用于治疗和检测癌症公开(公告)号：US20120076789A1
公开(公告)日：2012-03-29
申请号：US13243297
申请日：2011-09-23
申请人： Pia M. CHALLITA-EID , Rene S. Hubert , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Wangmao Ge , Aya Jakobovits
发明人： Pia M. CHALLITA-EID , Rene S. Hubert , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Wangmao Ge , Aya Jakobovits
CPC分类号： C07K16/30 , A61K39/00 , A61K2039/505 , C07K14/47
摘要： A novel gene (designated 121P1F1) and its encoded protein, and variants thereof, are described wherein 121P1F1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 121P1F1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 121P1F1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 121P1F1 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为121P1F1）及其编码的蛋白质及其变体，其中121P1F1在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，121P1F1提供诊断，预后， 癌症的预防和/或治疗靶标。 121P1F1基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与121P1F1反应的抗体或T细胞可用于主动或被动免疫。
-
79.发明授权Nucleic acids and corresponding proteins entitled 202P5A5 useful in treatment and detection of cancer 失效题为202P5A5的核酸和相应的蛋白质可用于治疗和检测癌症公开(公告)号：US08057996B2
公开(公告)日：2011-11-15
申请号：US11548626
申请日：2006-10-11
IPC分类号： C12Q1/68
CPC分类号： C12N5/0693 , A01K2217/05 , A01K2217/075 , A61K38/00 , A61K47/6851 , A61K2039/505 , C07K14/435 , C07K14/47 , C07K2319/00 , G01N33/57484 , Y02A50/466
摘要： A novel gene 202P5A5 and its encoded protein, and variants thereof, are described wherein 202P5A5 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 202P5A5 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 202P5A5 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 202P5A5 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因202P5A5及其编码的蛋白质及其变体，其中202P5A5在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，202P5A5提供诊断，预后，预防和/ 或癌症的治疗靶标。 202P5A5基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与202P5A5反应的抗体或T细胞可用于主动或被动免疫。
-
80.发明授权Nucleic acid and corresponding protein entitled 121P1F1 useful in treatment and detection of cancer 失效核酸和相应的蛋白质121P1F1可用于治疗和检测癌症公开(公告)号：US08039603B2
公开(公告)日：2011-10-18
申请号：US12473056
申请日：2009-05-27
申请人： Pia M. Challita-Eid , Rene S. Hubert , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Wangmao Ge , Aya Jakobovits
发明人： Pia M. Challita-Eid , Rene S. Hubert , Arthur B. Raitano , Mary Faris , Daniel E. H. Afar , Wangmao Ge , Aya Jakobovits
IPC分类号： C07H21/02
CPC分类号： C07K14/47 , A61K38/00 , A61K39/00 , A61K2039/505 , C07K16/30 , C07K2317/34 , G01N33/574 , Y02A50/466
摘要： A novel gene (designated 121P1F1) and its encoded protein, and variants thereof, are described wherein 121P1F1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 121P1F1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 121P1F1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 121P1F1 can be used in active or passive immunization.
摘要翻译： 描述了一种新型基因（称为121P1F1）及其编码的蛋白质及其变体，其中121P1F1在正常成人组织中表现出组织特异性表达，并且在表I中列出的癌症中异常表达。因此，121P1F1提供诊断，预后， 癌症的预防和/或治疗靶标。 121P1F1基因或其片段或其编码的蛋白质或其变体或其片段可用于引发体液或细胞免疫应答; 与121P1F1反应的抗体或T细胞可用于主动或被动免疫。
-
-
-
-
-
-
-
-
-
搜索结果
135 条记录 (耗时 0.08 秒)
