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163 条记录 (耗时 0.04 秒)

    Alkansulfonamides as endothelin antagonists
    73.
    发明授权
    Alkansulfonamides as endothelin antagonists 失效
    阿烷磺酰胺作为内皮素拮抗剂

    公开(公告)号：US07323465B2

    公开(公告)日：2008-01-29

    申请号：US10500485

    申请日：2002-12-10

    申请人： Martin Bolli ,  Christoph Boss ,  Martine Clozel ,  Walter Fischli ,  Thomas Weller

    发明人： Martin Bolli ,  Christoph Boss ,  Martine Clozel ,  Walter Fischli ,  Thomas Weller

    IPC分类号： C07D239/47 ,  A61K31/506

    CPC分类号： C07D239/47 ,  C07D239/52 ,  C07D239/545 ,  C07D239/56 ,  C07D401/14 ,  C07D403/14

    摘要： The invention relates to novel alkansulfonamides of structure (I), wherein R1 is a lowel alzyl group and the other variables are as defined in the description, and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists in the treatment and prevention of diseases associated to the endothelin system

    摘要翻译： 本发明涉及结构（I）的新型烷磺酰胺，其中R 1是低级烷基，其它变量如说明书中所定义，并且它们作为制备药物组合物中的活性成分的用途 。 本发明还涉及包括制备化合物的方法，含有这些化合物中的一种或多种的药物组合物，特别是其用作内皮素受体拮抗剂在治疗和预防与内皮素系统相关的疾病中的用途的相关方面

    System and Method for a Single Stage Tunable Ultra-Wideband Pulse Generator
    75.
    发明申请
    System and Method for a Single Stage Tunable Ultra-Wideband Pulse Generator 有权
    单级可调谐超宽带脉冲发生器的系统和方法

    公开(公告)号：US20070237208A1

    公开(公告)日：2007-10-11

    申请号：US11612713

    申请日：2006-12-19

    申请人： Erick Maxwell ,  Thomas Weller

    发明人： Erick Maxwell ,  Thomas Weller

    IPC分类号： H04B1/00

    CPC分类号： H03K5/12 ,  H03K3/33 ,  H03K5/06 ,  H04B1/7174

    摘要： The present invention provides a single-stage tunable Ultra-Wideband (UWB) pulse generator, by creating and differentiating a variable edge rate signal. Edge rate variability is introduced by first applying a step recovery diode (SRD) to compress the edges of the source and then applying a simple RC network to adjust the edge rate. Next, the resulting signal is differentiated using microstrip transmission lines. The tunable generator resulting from this approach demonstrates a Gaussian and monocycle pulses with good symmetry and low distortion over the tunable range.

    摘要翻译： 本发明通过创建和区分可变边缘速率信号来提供单级可调谐超宽带（UWB）脉冲发生器。 通过首先应用步骤恢复二极管（SRD）来压缩源的边缘，然后应用简单的RC网络来调整边缘速率来引入边缘率变化。 接下来，使用微带传输线对结果信号进行区分。 由该方法产生的可调谐发生器表现出在可调范围内具有良好对称性和低失真的高斯和单周期脉冲。

    Global equivalent circuit modeling system for substrate mounted circuit components incorporating substrate dependent characteristics
    76.
    发明授权
    Global equivalent circuit modeling system for substrate mounted circuit components incorporating substrate dependent characteristics 有权
    用于衬底安装的电路组件的全局等效电路建模系统，其包含基板相关特性

    公开(公告)号：US07269810B1

    公开(公告)日：2007-09-11

    申请号：US11163408

    申请日：2005-10-18

    申请人： Thomas Weller ,  John Capwell ,  Horace Gordon ,  Balaji Lakshminarayanan

    发明人： Thomas Weller ,  John Capwell ,  Horace Gordon ,  Balaji Lakshminarayanan

    IPC分类号： G06F17/50

    CPC分类号： G06F17/5022 ,  G06F17/5045

    摘要： The present invention is a substrate dependent circuit modeling system for substrate-mounted components. The height and dielectric constant of a substrate have a significant impact on the frequency response of such components, and these effects cannot be treated independently from the circuit model. The equivalent circuit parameters in the model must be made to vary in accordance with changes in the substrate. The invention includes the steps of selecting a substrate mounted electrical circuit component for which an equivalent circuit model is desired, determining equivalent circuit model input parameters, wherein some of which are dependent upon characteristics of the substrate upon which the component is mounted, for the selected component, representing the selected electrical circuit component mounted upon the substrate as an equivalent electrical circuit, formulating mathematical expressions based upon the input parameters, and creating a unique equivalent circuit model for the component mounted upon the given substrate, the unique equivalent circuit model representing the mounting of the component upon the given substrate wherein the equivalent circuit model provides behavior and performance predictions of the component based upon the given substrate characteristics.

    摘要翻译： 本发明是用于基板安装部件的基板相关电路建模系统。 衬底的高度和介电常数对这些部件的频率响应有显着影响，这些影响不能独立于电路模型进行处理。 必须使模型中的等效电路参数根据衬底的变化而变化。 本发明包括以下步骤：选择需要等效电路模型的衬底安装的电路部件，确定等效电路模型输入参数，其中一些取决于所安装部件的衬底的特性，用于所选择的 代表安装在基板上的所选择的电路部件作为等效电路，基于输入参数来制定数学表达式，并为安装在给定基板上的部件创建唯一的等效电路模型，所述独特的等效电路模型表示 将组件安装在给定的基板上，其中等效电路模型基于给定的基板特性提供部件的行为和性能预测。