公开(公告)号：US20080319309A1

公开(公告)日：2008-12-25

申请号：US12096995

申请日：2006-12-08

申请人： Joerg Bredno ,  Alexandra Groth ,  Juergen Weese ,  Tom Bruijns ,  Peter M.J. Rongen ,  Roel Hermans ,  Heidrun Steinhauser

发明人： Joerg Bredno ,  Alexandra Groth ,  Juergen Weese ,  Tom Bruijns ,  Peter M.J. Rongen ,  Roel Hermans ,  Heidrun Steinhauser

IPC分类号： A61B5/055 ,  A61B6/00

CPC分类号： G01R33/5635 ,  A61B5/0275 ,  A61B5/0456 ,  A61B6/481 ,  A61B6/504 ,  A61B6/507 ,  A61B8/06 ,  A61M5/007 ,  A61M5/1723 ,  A61M2230/04 ,  G01R33/281 ,  G01R33/5601 ,  G06T7/0012 ,  G06T7/20 ,  G06T2207/30101

摘要： A system, apparatus and method are provided for measuring and removing the influence of pulsatility on contrast agent flow in a region of interest of a vascular system of a patient. Once the change of blood speed over the cardiac cycle is known (pulsatility), this influence is removed from acquired image sequence for outcome control such that “quasi-stationary”, regular flow acquisition is passed on to subsequent visualization and analysis processes. A contrast agent injector is also provided that simultaneously measures and uses ECG to inject a known contrast agent at a fixed point over the cardiac cycle or such that a known amount of contrast agent will arrive at a known time at a region of interest in the vasculature of a patient, thus controlling one of the main unwanted variables in an acquisition of blood flow sequences.

摘要翻译： 提供了一种系统，装置和方法，用于测量和消除脉搏对患者血管系统感兴趣区域中造影剂流动的影响。 一旦知道心搏周期的血液速度变化（脉动），这种影响就从获得的结果控制图像序列中消除，从而将“准静态”常规流量采集传递给随后的可视化和分析过程。 还提供造影剂注射器，其同时测量并使用ECG在心脏周期上的固定点注入已知的造影剂，或使已知量的造影剂在脉管系统中的感兴趣区域的已知时间到达 因此在获取血流序列时控制主要不需要的变量之一。

公开(公告)号：US07167172B2

公开(公告)日：2007-01-23

申请号：US10091050

申请日：2002-03-05

申请人： Michael Kaus ,  Anja Hennemuth ,  Vladimir Pekar ,  Juergen Weese

发明人： Michael Kaus ,  Anja Hennemuth ,  Vladimir Pekar ,  Juergen Weese

IPC分类号： G06T15/00

CPC分类号： G06T7/149 ,  G06T7/12 ,  G06T2207/10072 ,  G06T2207/30004

摘要： The invention relates to a method of segmenting a three-dimensional structure, contained in an object, from one or more two-dimensional images which represent a slice of the object. The method utilizes a deformable model whose surface is formed by a network of meshes which connect network points on the surface of the model to one another. First there are determined the meshes which intersect at least one image and a point on the surface of the structure to be segmented is searched along a search line which traverses the mesh and extends in the image. Subsequently, the position of the network points of the model is calculated anew. These steps are repeated a number of times and the model ultimately obtained, that is, after several deformations, is considered to be the segmentation of the three-dimensional structure from the two-dimensional images.

摘要翻译： 本发明涉及一种从一个或多个二维图像中分割包含在对象中的三维结构的方法，所述二维图像表示对象的切片。 该方法利用可变模型，其表面由网格网络形成，网格网络将模型表面上的网络点彼此连接。 首先确定与至少一个图像相交的网格，并且沿着要遍历网格的搜索线搜索要分割的结构的表面上的点，并在图像中延伸。 随后，重新计算模型网络点的位置。 这些步骤重复多次，并且最终获得的模型，即，在几个变形之后，被认为是来自二维图像的三维结构的分割。

公开(公告)号：US20050288577A1

公开(公告)日：2005-12-29

申请号：US10536843

申请日：2003-11-27

申请人： Juergen Weese

发明人： Juergen Weese

IPC分类号： A61B8/00 ,  A61B8/12 ,  G06T17/00 ,  G06T17/40 ,  A61B6/00

CPC分类号： A61B8/12 ,  A61B5/0066 ,  G06T19/00 ,  G06T2210/41

摘要： The invention relates to the assistance of the navigation of a catheter (1) in a vessel (2). A sequence of cross-sectional images of the portion of the vessel that is of interest is first obtained with the help of an intravascular ultrasound (IVUS) probe (3) and stored as a roadmap of the vessel. A cross-sectional image (10) that is obtained at the current position of the IVUS probe (3) can then be sorted to the position on the roadmap that is the best fit. A model (3′) of the probe, and a model (11′) of the instrument (a stent (11), for example) coupled to the probe, can be shown on a display (6) at the corresponding position on the roadmap.

摘要翻译： 本发明涉及导管（1）在血管（2）中导航的辅助。 首先通过血管内超声（IVUS）探针（3）的帮助首先获得感兴趣的血管部分的横截面图像序列，并存储为血管的路线图。 在IVUS探头（3）的当前位置处获得的横截面图像（10）可以被分类到路线图上最适合的位置。 耦合到探针的探针的模型（3'）和与仪器（例如支架）相连的模型（11'）可以在显示器（6）上显示在 路线图