公开(公告)号：US06636758B2

公开(公告)日：2003-10-21

申请号：US09847769

申请日：2001-05-01

申请人： Diana Sanchez ,  Ivan Sepetka ,  Maureen Bensing ,  Richard A. Helkowski

发明人： Diana Sanchez ,  Ivan Sepetka ,  Maureen Bensing ,  Richard A. Helkowski

IPC分类号： A61B600

CPC分类号： A61B17/12113 ,  A61B6/12 ,  A61B17/12022 ,  A61B17/1214 ,  A61B90/39 ,  A61B2017/22042 ,  A61B2090/061 ,  A61B2090/063 ,  A61M25/0108

摘要： This is a medical device, specifically used in surgery. It is a wire having distal radio-opaque markers and may be used, for instance, in endovascular procedures as a marker wire for estimating or referencing the structural attributes of internal physical features. In addition, the inventive marker wire may be used as a guide wire for a catheter used in endovascular procedures.

公开(公告)号：US06458119B1

公开(公告)日：2002-10-01

申请号：US08909004

申请日：1997-08-08

申请人： Alejandro Berenstein ,  Ivan Sepetka

发明人： Alejandro Berenstein ,  Ivan Sepetka

IPC分类号： A61B1700

CPC分类号： A61B17/12022 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/1214 ,  A61B17/1215 ,  A61B17/12163 ,  A61B90/39 ,  A61B2017/00526 ,  A61B2017/00539 ,  A61B2017/12063 ,  A61B2017/1209

摘要： An exceptionally flexible, ultra-soft vasoocclusive or embolism forming device made of a material which may be a braid, coil, or chain which forms a long, thin thread-like device having little rigidity or column strength. The device is sufficiently flexible and small that it may be hydraulically delivered to a site within the vasculature of a human body using an injected drug or fluid flush through a catheter.

摘要翻译： 一种非常灵活的超软血管收缩或栓塞形成装置，其由可能是编织物，线圈或链的材料制成，其形成具有很小刚度或柱强度的长而细的线状装置。 该装置具有足够的柔性和小度，使得其可以使用注射的药物或通过导管冲洗的流体液压递送到人体脉管系统内的部位。

公开(公告)号：US06346077B1

公开(公告)日：2002-02-12

申请号：US08789751

申请日：1997-01-27

申请人： Charles S. Taylor ,  William N. Aldrich ,  Thomas L. Baughman ,  Federico J. Benetti ,  Brian J. Bennett ,  Michael J. Billig ,  Thomas J. Fogarty ,  John J. Frantzen ,  Richard S. Ginn ,  Robert C. Glines ,  Harry L. Green ,  Dwight P. Morejohn ,  Brent Regan ,  Eugene E. Reis ,  Amr Salahieh ,  Ivan Sepetka ,  Benjamin Sherman ,  Christian Skieller ,  Valavanur A. Subramanian ,  Gary B. Weller ,  William F. Witt

发明人： Charles S. Taylor ,  William N. Aldrich ,  Thomas L. Baughman ,  Federico J. Benetti ,  Brian J. Bennett ,  Michael J. Billig ,  Thomas J. Fogarty ,  John J. Frantzen ,  Richard S. Ginn ,  Robert C. Glines ,  Harry L. Green ,  Dwight P. Morejohn ,  Brent Regan ,  Eugene E. Reis ,  Amr Salahieh ,  Ivan Sepetka ,  Benjamin Sherman ,  Christian Skieller ,  Valavanur A. Subramanian ,  Gary B. Weller ,  William F. Witt

IPC分类号： A61B132

CPC分类号： A61B17/0218 ,  A61B17/00234 ,  A61B17/02 ,  A61B17/0206 ,  A61B17/0642 ,  A61B17/12 ,  A61B17/3421 ,  A61B17/3423 ,  A61B90/00 ,  A61B2017/00243 ,  A61B2017/00557 ,  A61B2017/00703 ,  A61B2017/00858 ,  A61B2017/0243 ,  A61B2017/1139 ,  A61B2017/2825 ,  A61B2017/2913 ,  A61B2017/2929 ,  A61B2017/306 ,  A61B2017/349

摘要： The invention is methods and devices which a surgeon may use to stabilize the beating heart during a surgical procedure on the heart. Pursuant to the invention, a stabilizing device is introduced through an opening in the chest and brought into contact with the beating heart. By contacting the heart with the device and by exerting a stabilizing force on the device, the motion of the heart caused by the contraction of the heart muscles is effectively eliminated such that the heart is stabilized and the site of the surgery moves only minimally if at all. Typically, in separate steps, the surgeon contacts the heart with the stabilizing means, assesses the degree of movement of the anastomosis site, and exerts a force on the stabilizing means such that the contraction of the beating heart causes orgy minimal excess motion at the surgery site. By fixing the position of the stabilizing means in a configuration where the motion of the beating heart is effectively eliminated, the surgeon is able to stabilize the beating heart for the duration of the procedure. The stabilizing means may be attached to a rigid support or may be attached to a semi-rigid support which is rendered motionless mechanically, chemically, or by human intervention. In certain preferred embodiments, the stabilizing means is affixed to a semi-rigid support which is caused to become rigid, by any of a variety of techniques, such that the position of the stabilizing means becomes fixed by the support, and the heart remains substantially motionless for the duration of the procedure.

摘要翻译： 本发明是外科医生可以在心脏手术过程中稳定跳动心脏的方法和装置。 根据本发明，稳定装置通过胸部的开口引入并与打浆心接触。 通过将心脏与装置接触并且通过在装置上施加稳定力，由心脏肌肉收缩引起的心脏的运动被有效地消除，使得心脏稳定，并且手术部位仅在最小程度上移动，如果在 所有。 通常，在单独的步骤中，外科医生将心脏与稳定装置接触，评估吻合部位的移动程度，并对稳定装置施加力，使得跳动心脏的收缩导致手术时的最小过度运动 现场。 通过将稳定装置的位置固定在跳动心脏的运动被有效地消除的构造中，外科医生能够在手术期间稳定跳动的心脏。 稳定装置可以附接到刚性支撑件，或者可以附接到半刚性支撑件，其通过机械，化学方式或通过人为干预使其不动。 在某些优选实施例中，稳定装置通过各种技术中的任一种被固定到半刚性支撑件上，使其变得刚性，使得稳定装置的位置由支撑件固定，并且心脏基本保持 在程序期间不动。

公开(公告)号：US06315717B1

公开(公告)日：2001-11-13

申请号：US09550447

申请日：2000-04-17

申请人： Federico J. Benetti ,  Charles S. Taylor ,  Ivan Sepetka ,  Amr Salahieh ,  Robert C. Glines ,  William N. Aldrich ,  Brent Regan ,  John J. Frantzen

发明人： Federico J. Benetti ,  Charles S. Taylor ,  Ivan Sepetka ,  Amr Salahieh ,  Robert C. Glines ,  William N. Aldrich ,  Brent Regan ,  John J. Frantzen

IPC分类号： A61B132

CPC分类号： A61B17/0218 ,  A61B17/00234 ,  A61B17/02 ,  A61B17/0206 ,  A61B17/0642 ,  A61B17/12 ,  A61B17/3421 ,  A61B17/3423 ,  A61B90/00 ,  A61B2017/00243 ,  A61B2017/00557 ,  A61B2017/00703 ,  A61B2017/00858 ,  A61B2017/0243 ,  A61B2017/1139 ,  A61B2017/2825 ,  A61B2017/2913 ,  A61B2017/2929 ,  A61B2017/306 ,  A61B2017/349

摘要： Methods and devices used to stabilize a beating heart during a surgical procedure on the heart are disclosed. The stabilizing device is introduced through an opening through the chest and brought into contact with the beating heart, and by exerting a stabilizing force on the device, the motion of the heart caused by the contractions of the heart muscles is effectively eliminated. Accordingly, the heart is stabilized and movement of the site of the surgery is minimized. Typically, in separate steps, a surgeon contacts the heart with the stabilizing device, assesses the degree of movement of the anastomosis site, and exerts a force with a stabilizing device such that the contractions of the beating heart causes only minimal excess motion at the surgery site. The stabilizing device may be attached to a rigid support or may be attached to a semi-rigid support which is rendered motionless mechanically, chemically or by human intervention.

摘要翻译： 公开了用于在外科手术中心脏稳定跳动心脏的方法和装置。 稳定装置通过穿过胸部的开口被引入与打心的心脏接触，并且通过在装置上施加稳定力，有效地消除了由心脏肌肉收缩引起的心脏运动。 因此，心脏稳定并且手术部位的运动被最小化。 通常，在单独的步骤中，外科医生将心脏与稳定装置接触，评估吻合部位的移动程度，并用稳定装置施加力，使得跳动心脏的收缩在手术时仅引起极小的过度运动 现场。 稳定装置可以附接到刚性支撑件或者可以附接到半刚性支撑件，其通过机械地，化学地或通过人为干预使其静止。

公开(公告)号：US06190311B1

公开(公告)日：2001-02-20

申请号：US08850150

申请日：1997-05-02

申请人： Robert C. Glines ,  Ivan Sepetka

发明人： Robert C. Glines ,  Ivan Sepetka

IPC分类号： A61B130

CPC分类号： A61B17/0293 ,  A61B17/0206 ,  A61B2017/0237

摘要： An instrument platform and retractor, for holding and organizing cannulas, instruments and sutures during a surgical procedure, wherein the instrument platform has a platform body which is mountable to the retractor and includes a central opening and cannula notches formed therein adjacent to the central opening for securing cannulas during a surgical procedure. The platform body also includes suture grips and instrument mounts for securing surgical instruments and sutures during a surgical procedure. The retractor includes a pair of blades and a spreader mechanism detachably mounted to blade arms.

摘要翻译： 一种用于在手术过程中保持和组织插管，器械和缝合线的仪器平台和牵开器，其中所述仪器平台具有可安装到所述牵开器的平台体，并且包括邻近所述中心开口形成的中心开口和套管凹口， 在外科手术过程中确保插管。 平台体还包括缝合夹和仪器座，用于在手术过程中固定手术器械和缝合线。 牵开器包括一对刀片和可拆卸地安装到刀臂上的吊架机构。

公开(公告)号：US5944736A

公开(公告)日：1999-08-31

申请号：US903516

申请日：1997-07-30

申请人： Charles S. Taylor ,  William N. Aldrich ,  Federico J. Benetti ,  Richard S. Ginn ,  Dwight P. Morejohn ,  Brent Regan ,  Eugene E. Reis ,  Ivan Sepetka ,  William F. Witt

发明人： Charles S. Taylor ,  William N. Aldrich ,  Federico J. Benetti ,  Richard S. Ginn ,  Dwight P. Morejohn ,  Brent Regan ,  Eugene E. Reis ,  Ivan Sepetka ,  William F. Witt

IPC分类号： A61B17/02 ,  A61B17/34 ,  A61B19/00

CPC分类号： A61B17/3423 ,  A61B17/0206 ,  A61B90/50 ,  A61B17/025 ,  A61B17/3476 ,  A61B2017/349

摘要： An access platform having a first and a second blade interconnected to a spreader member that laterally drives the blades apart or together and a sternal pad interconnected to a blade. The superior blade is pivotally coupled to the spreader member such that it naturally rises as the blades are separated. Alternatively, a vertical displacement member is operably interconnected to a blade and the spreader member and is used to vertically displace the interconnected superior blade and, thus, increase a surgeon's working space and visual access for the dissection of an internal mammary artery. A tissue retractor is interconnected to the blades to draw the soft tissue around an incision away from the surgeon's working area.

公开(公告)号：US5871496A

公开(公告)日：1999-02-16

申请号：US835675

申请日：1997-04-10

申请人： Richard S. Ginn ,  Hani Shennib ,  Charles S. Taylor ,  Ivan Sepetka

发明人： Richard S. Ginn ,  Hani Shennib ,  Charles S. Taylor ,  Ivan Sepetka

IPC分类号： A61B17/00 ,  A61B17/02 ,  A61B17/28 ,  A61B17/32 ,  A61B18/14

CPC分类号： A61B17/00008 ,  A61B17/02 ,  A61B17/00234 ,  A61B17/320016 ,  A61B2017/00867 ,  A61B2017/00969 ,  A61B2017/2905 ,  A61B2017/2927 ,  A61B2018/00916 ,  A61B2018/1253 ,  A61B2018/1407 ,  A61B2018/1435

摘要： A surgical instrument is configured to aid in performing a procedure of detaching an internal mammary artery (IMA) and the like, from the connecting tissues and side branch vessels which surround the artery in its native location, wherein the detaching procedure is preliminary to the performing of a coronary artery bypass grafting procedure and wherein the IMA is detached via a minimally invasive thoracotomy. To this end, an elongated slender rod includes a handle at its proximal end and an artery engaging loop, arc, fork configuration, or hook at its distal working end. Embodiments may incorporate electrosurgical capability or electrical insulation. A surgeon thus has means for harvesting an intact and undamaged graft vessel from its native location through a minimally invasive incision with enhanced speed, visibility, and freedom of motion.

公开(公告)号：US5776154A

公开(公告)日：1998-07-07

申请号：US603329

申请日：1996-02-20

申请人： Charles S. Taylor ,  John J. Frantzen ,  Ivan Sepetka

发明人： Charles S. Taylor ,  John J. Frantzen ,  Ivan Sepetka

IPC分类号： A61B17/00 ,  A61B17/28 ,  A61B17/32

CPC分类号： A61B17/32 ,  A61B17/320016 ,  A61B2017/00243 ,  A61B2017/00703 ,  A61B2017/00778 ,  A61B2017/2925 ,  A61B2017/320052

摘要： Surgical instruments and methods for making substantially linear incisions, especially through the wall of vessels, such as arteries, specifically designed for coronary artery bypass graft procedures (CABG) on the beating heart. The invention is particularly useful to create the incision in the artery to which a bypass graft is sewn, typically the left anterior descending artery (LAD). The instruments allow incisions to be rapidly made, precisely measured, and cleanly formed so that a bypass graft can be rapidly sewn in place, without undue trauma to surrounding tissue and excessive loss of blood. In one embodiment, a hand-held instrument has a cutting edge formed on the interior edge of a curved blade fixed near the end of the instrument. The tip of the blade has a point for penetrating the vessel wall which may have several alternate shapes to facilitate penetration of the vessel wall while minimizing trauma to the surrounding tissue. In another embodiment the hand-held instrument includes a moveable member which creates an incision by engaging a cutting blade against a stop, cutting tissue therebetween, the stop including a pointed tip similar to the previous embodiment. In another embodiment, the instrument features a motion-canceling member which compensates for the movement of the target surface to be incised. This embodiment has a cutting blade which is manipulated from a handle which is isolated from the movement of the tissue containing or proximate to the target of the incision.

摘要翻译： 用于进行基本上线性切口的手术器械和方法，特别是通过专门设计用于搏动心脏上的冠状动脉旁路移植手术（CABG）的诸如动脉的血管壁。 本发明特别有用于在缝合旁路移植物的动脉中产生切口，通常为左前降支动脉（LAD）。 这些仪器允许快速地进行切割，精确测量和清洁地形成，使得旁路移植物可以快速缝合就位，而不会对周围组织造成过度的创伤和过度的血液损失。 在一个实施例中，手持式仪器具有形成在靠近仪器端部的弯曲刀片的内边缘上的切割刃。 叶片的尖端具有穿透血管壁的点，该点可以具有若干替代形状，以促进血管壁的穿透，同时最小化对周围组织的创伤。 在另一个实施例中，手持式仪器包括可移动构件，其通过将切割刀片接合止挡件而形成切口，在其间切割组织，止动件包括类似于先前实施例的尖端。 在另一个实施例中，仪器具有补偿待切割的目标表面的移动的运动消除构件。 该实施例具有从手柄操纵的切割刀片，该手柄与包含或接近切口目标的组织的运动隔离。

公开(公告)号：US5730757A

公开(公告)日：1998-03-24

申请号：US604161

申请日：1996-02-20

申请人： Federico J. Benetti ,  Charles S. Taylor ,  William N. Aldrich ,  Ivan Sepetka ,  Robert G. Matheny ,  Eugene E. Reis ,  Brent Regan ,  Richard M. Ferrari

发明人： Federico J. Benetti ,  Charles S. Taylor ,  William N. Aldrich ,  Ivan Sepetka ,  Robert G. Matheny ,  Eugene E. Reis ,  Brent Regan ,  Richard M. Ferrari

IPC分类号： A61B17/02 ,  A61B17/34 ,  A61B19/00

CPC分类号： A61B17/3423 ,  A61B17/0206 ,  A61B90/50 ,  A61B17/025 ,  A61B2017/3427 ,  A61B2017/349

摘要： An access platform having a first and a second blade interconnected to a spreader member that laterally drives the blades apart or together and support pads interconnected to the first blade. A torsional member is operably interconnected to the first blade and the spreader member and is used to vertically displace the first blade in either direction and, thus, increase a surgeon's working space and visual access for the dissection of an internal mammary artery. A tissue retractor interconnected to the blades is used to draw the soft tissue around an incision away from the surgeon's working area.

摘要翻译： 一种进入平台，其具有与扩展构件相互连接的第一和第二叶片，所述第一和第二叶片横向地驱动叶片彼此分离或一起，并且支撑与第一叶片互连的垫。 扭转构件可操作地连接到第一叶片和展开构件，并且用于沿任一方向垂直地移位第一叶片，并且因此增加外科医生的工作空间和用于内部乳房动脉解剖的视觉进入。 使用与叶片互连的组织牵开器将软组织围绕切口远离外科医生的工作区域。

公开(公告)号：US5429605A

公开(公告)日：1995-07-04

申请号：US188382

申请日：1994-01-26

申请人： Richling: Bernd ,  Ivan Sepetka ,  Uriel H. Chee ,  Liem Ho ,  Phong Pham

发明人： Richling: Bernd ,  Ivan Sepetka ,  Uriel H. Chee ,  Liem Ho ,  Phong Pham

IPC分类号： A61M25/00 ,  A61F2/958 ,  A61M29/00

CPC分类号： A61M25/1006 ,  A61M25/0054 ,  A61M25/1025

摘要： This invention is a microballoon tipped catheter. The catheter has a shaft which is of varying flexibility with the most flexible portion towards the distal tip. The balloon, located near the distal tip of the catheter, is typically of an elastic material, is quite flexible in its own right when deflated, and is quite small. The catheter shaft has a main lumen extending from the proximal end to the distal end so to allow the use of a guidewire in placing the catheter's distal tip in remote regions of the vasculature and for delivery of drugs, diagnostics, and other biologics to those regions. The catheter shaft has a wall that desirably is of a multilayer construction. The wall preferably includes an independent lumen, which may be formed from a small diameter tubing that is placed between layers of the wall, for the inflation and deflation of the microballoon. The inflation lumen proceeds from the proximal end of the catheter and terminates near the distal end of the catheter but within the microballoon. This catheter is especially useful in treating disease within the high pressure vessels of the brain with drugs or other therapeutic agents and permits temporary blockage of blood flow and thereby allow better absorption of those active agents.

摘要翻译： 本发明是一种微气囊导管。 该导管具有一个具有不同柔性的轴，朝向远侧末端具有最柔韧的部分。 位于导管远侧末端附近的气囊通常是弹性材料，当放气时本身是相当灵活的，并且相当小。 导管轴具有从近端延伸到远端的主腔，以便允许使用导丝将导管的远侧末端放置在脉管系统的偏远区域中并用于将药物，诊断和其它生物制剂递送至那些区域 。 导管轴具有期望地具有多层结构的壁。 壁优选地包括独立的内腔，其可以由放置在壁的层之间的小直径管形成，用于微气泡的充气和放气。 膨胀腔从导管的近端延伸，并在导管的远端附近终止，但在微球内。 该导管特别适用于用药物或其它治疗剂治疗脑高压血管内的疾病，并允许临时阻塞血流，从而允许更好地吸收那些活性剂。