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![THERAPEUTICALLY USEFUL SUBSTITUTED HYDROPYRIDO [3,2,1-ij] QUINOLINE COMPOUNDS](/abs-image/US/2012/12/06/US20120309782A1/abs.jpg.150x150.jpg)
公开(公告)号：US20120309782A1
公开(公告)日：2012-12-06
申请号：US13569418
申请日：2012-08-08
申请人： Santosh C. Sinha , Smita S. Bhat , Ken Chow , Richard L. Beard , John E. Donello , Michael E. Garst
发明人： Santosh C. Sinha , Smita S. Bhat , Ken Chow , Richard L. Beard , John E. Donello , Michael E. Garst
IPC分类号： A61K31/4745 , A61K31/4375 , A61P9/10 , A61P27/02 , A61P27/06
CPC分类号： C07D471/04 , C07D471/06
摘要： Disclosed herein are compounds represented by the structural formula: therapeutic methods, compositions, and medicaments related thereto are also disclosed.
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![THERAPEUTICALLY USEFUL SUBSTITUTED HYDROPYRIDO [3,2,1-ij] QUINOLINE COMPOUNDS](/abs-image/US/2012/08/23/US20120214838A1/abs.jpg.150x150.jpg)
72.发明申请THERAPEUTICALLY USEFUL SUBSTITUTED HYDROPYRIDO [3,2,1-ij] QUINOLINE COMPOUNDS 失效可治疗有效的替代羟脯氨酸[3,2,1-ij]喹啉化合物公开(公告)号：US20120214838A1
公开(公告)日：2012-08-23
申请号：US13461398
申请日：2012-05-01
申请人： Santosh C. Sinha , Smita S. Bhat , Ken Chow , Richard L. Beard , John E. Donello , Michael E. Garst
发明人： Santosh C. Sinha , Smita S. Bhat , Ken Chow , Richard L. Beard , John E. Donello , Michael E. Garst
IPC分类号： A61K31/4375 , A61P29/00 , A61P25/06 , A61P1/00 , A61P17/02 , A61P11/06 , A61P11/00 , A61P9/00 , A61P9/10 , A61P25/02 , A61P27/02
CPC分类号： C07D471/04 , C07D471/06
摘要： Disclosed herein are compounds represented by the structural formula: therapeutic methods, compositions, and medicaments related thereto are also disclosed.
摘要翻译： 本文公开了由结构式表示的化合物：还公开了与之相关的治疗方法，组合物和药物。
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73.发明申请Novel 1-(1-OXO-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)Urea Derivatives As N-FORMYL Peptide Receptor Like-1 (FPRL-1) Receptor Modulators 有权新型1-（1-氧代-1,2,3,4-四氢喹啉-7-YL）脲衍生物作为N-FORMYL肽受体样-1（FPRL-1）受体调节剂公开(公告)号：US20120208842A1
公开(公告)日：2012-08-16
申请号：US13370472
申请日：2012-02-10
IPC分类号： A61K31/472 , A61P27/02 , A61P29/00 , C07D217/24
CPC分类号： C07D217/24 , C07D401/06 , C07D401/14 , C07D405/14
摘要： The present invention relates to novel 1-(1-Oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide receptor like-1 (FPRL-1) receptor.
摘要翻译： 本发明涉及新的1-（1-氧代-1,2,3,4-四氢异喹啉-7-基）脲衍生物，其制备方法，含有它们的药物组合物及其作为药物用作N- 甲酰肽受体1（FPRL-1）受体。
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公开(公告)号：US09090624B2
公开(公告)日：2015-07-28
申请号：US13565478
申请日：2012-08-02
申请人： Vidyasagar Vuligonda , Richard L. Beard , Thong Vu , John E. Donello , Gerard Rodrigues , Veena Viswanath , Michael E. Garst
发明人： Vidyasagar Vuligonda , Richard L. Beard , Thong Vu , John E. Donello , Gerard Rodrigues , Veena Viswanath , Michael E. Garst
IPC分类号： C07D495/04 , A61K31/517 , A61K31/519 , C07D401/12
CPC分类号： C07D495/04 , C07D401/12
摘要： The present invention relates to novel aromatic bicyclic derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the CXCR4 receptor.
摘要翻译： 本发明涉及新的芳族二环衍生物，其制备方法，含有它们的药物组合物及其作为药物作为CXCR4受体调节剂的用途。
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公开(公告)号：US08614326B2
公开(公告)日：2013-12-24
申请号：US12674180
申请日：2008-08-21
IPC分类号： C07D215/38
CPC分类号： C07D277/34 , C07D215/52 , C07D401/04 , C07D409/04
摘要： Disclosed herein is a stable compound having a structure formula (I): therapeutic methods, compositions, and medicaments related thereto are also disclosed.
摘要翻译： 本文公开了具有结构式（I）的稳定化合物：还公开了与之相关的治疗方法，组合物和药物。
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76.发明授权1-(1-OXO-1,2,3,4-tetrahydroisoquinolin-7-YL)urea derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators 有权作为N-甲酰基肽受体1（FPRL-1）受体调节剂的1-（1-氧代-1,2,3,4-四氢异喹啉-7-YL）脲衍生物公开(公告)号：US08580817B2
公开(公告)日：2013-11-12
申请号：US13370472
申请日：2012-02-10
IPC分类号： C07D217/24 , C07D401/02 , A61K31/47
CPC分类号： C07D217/24 , C07D401/06 , C07D401/14 , C07D405/14
摘要： The present invention relates to novel 1-(1-Oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)urea derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide receptor like-1 (FPRL-1) receptor.
摘要翻译： 本发明涉及新的1-（1-氧代-1,2,3,4-四氢异喹啉-7-基）脲衍生物，其制备方法，含有它们的药物组合物及其作为药物用作N- 甲酰肽受体1（FPRL-1）受体。
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![Therapeutically useful substituted hydropyrido [3,2,1-ij] quinoline compounds](/abs-image/US/2013/04/30/US08431702B2/abs.jpg.150x150.jpg)
77.发明授权Therapeutically useful substituted hydropyrido [3,2,1-ij] quinoline compounds 失效治疗上有用的取代氢吡啶并[3,2,1-ij]喹啉化合物公开(公告)号：US08431702B2
公开(公告)日：2013-04-30
申请号：US13569418
申请日：2012-08-08
申请人： Santosh C. Sinha , Smita S. Bhat , Ken Chow , Richard L. Beard , John E. Donello , Michael E. Garst
发明人： Santosh C. Sinha , Smita S. Bhat , Ken Chow , Richard L. Beard , John E. Donello , Michael E. Garst
IPC分类号： C07D471/00 , C07D451/00 , A61K31/44
CPC分类号： C07D471/04 , C07D471/06
摘要： Disclosed herein are compounds represented by the structural formula: therapeutic methods, compositions, and medicaments related thereto are also disclosed.
摘要翻译： 本文公开了由结构式表示的化合物：还公开了与之相关的治疗方法，组合物和药物。
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公开(公告)号：US20130035347A1
公开(公告)日：2013-02-07
申请号：US13565478
申请日：2012-08-02
申请人： Vidyasagar Vuligonda , Richard L. Beard , Thong Vu , John E. Donello , Gerard Rodrigues , Veena Viswanath , Michael E. Garst
发明人： Vidyasagar Vuligonda , Richard L. Beard , Thong Vu , John E. Donello , Gerard Rodrigues , Veena Viswanath , Michael E. Garst
IPC分类号： A61K31/517 , C07D495/04 , A61K31/519 , A61P27/02 , A61P27/06 , A61P29/00 , A61P37/00 , A61P25/00 , A61P1/00 , A61P1/04 , A61P19/04 , A61P11/06 , A61P11/00 , A61P3/10 , A61P9/10 , A61P17/06 , A61P19/02 , A61P37/06 , A61P17/00 , A61P35/00 , A61P35/04 , C07D401/12
CPC分类号： C07D495/04 , C07D401/12
摘要： The present invention relates to novel aromatic bicyclic derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the CXCR4 receptor.
摘要翻译： 本发明涉及新的芳族二环衍生物，其制备方法，含有它们的药物组合物及其作为药物作为CXCR4受体调节剂的用途。
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79.发明申请公开(公告)号：US20120157444A1
公开(公告)日：2012-06-21
申请号：US13316762
申请日：2011-12-12
申请人： Haiqing Yuan , Richard L. Beard , Xiaoxia Liu , John E. Donello , Veena Viswanath , Michael E. Garst
发明人： Haiqing Yuan , Richard L. Beard , Xiaoxia Liu , John E. Donello , Veena Viswanath , Michael E. Garst
IPC分类号： A61K31/55
CPC分类号： A61K31/381 , A61K31/343 , A61K31/37 , A61K31/404 , A61K31/4155 , A61K31/4196 , A61K31/422 , A61K31/423 , A61K31/4245 , A61K31/427 , A61K31/428 , A61K31/429 , A61K31/4436 , A61K31/4709 , A61K31/4725 , A61K31/497 , A61K31/498 , A61K31/506 , A61K31/5377 , A61K31/538 , A61K31/5383 , A61K31/55 , A61K31/635 , C07C311/21 , C07C311/44 , C07D231/18 , C07D307/82 , C07D333/34 , C07D405/12 , C07D407/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D498/04 , C07D513/04
摘要： The present invention relates to novel bis-sulfonamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine receptors.
摘要翻译： 本发明涉及新的双磺酰胺衍生物，其制备方法，含有它们的药物组合物及其作为药物作为趋化因子受体调节剂的用途。
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公开(公告)号：US08193203B2
公开(公告)日：2012-06-05
申请号：US12467575
申请日：2009-05-18
申请人： Richard L. Beard , Tien T. Duong , Thong H. Vu , Vidyasagar Vuligonda , John E. Donello , Michael E. Garst , Gerard A. Rodrigues
发明人： Richard L. Beard , Tien T. Duong , Thong H. Vu , Vidyasagar Vuligonda , John E. Donello , Michael E. Garst , Gerard A. Rodrigues
IPC分类号： A01N43/54 , A61K31/517 , C07D239/72
CPC分类号： C07D401/12
摘要： A compound represented by the structural formula: Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
摘要翻译： 由结构式表示的化合物：还公开了与其有关的治疗方法，组合物和药物。
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