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71.发明授权Systems, devices, methods, and compositions including targeted ferromagnetic structures 有权包括目标铁磁结构的系统，装置，方法和组合物公开(公告)号：US08063636B2
公开(公告)日：2011-11-22
申请号：US12455297
申请日：2009-05-29
IPC分类号： G01V3/00
CPC分类号： G01R33/383 , G01R33/465 , G01R33/48 , G01R33/5601
摘要： Magnetic resonance systems, devices, methods, and compositions are provided. A nuclear magnetic resonance imaging composition includes, but is not limited to, a plurality of target-selective ferromagnetic microstructures configured to generate a time-invariant magnetic field within at least a portion of one or more internal surface-defined voids.
摘要翻译： 提供了磁共振系统，装置，方法和组合物。 核磁共振成像组合物包括但不限于多个目标选择性铁磁微结构，其被配置为在一个或多个内表面限定的空隙的至少一部分内产生时不变的磁场。
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72.发明申请Systems, devices, methods, and compositions including ferromagnetic structures 审中-公开包括铁磁结构的系统，装置，方法和组合公开(公告)号：US20100303733A1
公开(公告)日：2010-12-02
申请号：US12455273
申请日：2009-05-29
CPC分类号： A61K49/1818
摘要： Magnetic resonance systems, devices, methods, and compositions are provided. A nuclear magnetic resonance imaging composition includes, but is not limited to, a plurality of ferromagnetic microstructures configured to generate a time-invariant magnetic field within at least a portion of one or more internal surface-defined voids. In an embodiment, at least one of the plurality of ferromagnetic microstructures includes one or more targeting moieties attached thereof.
摘要翻译： 提供了磁共振系统，装置，方法和组合物。 核磁共振成像组合物包括但不限于多个铁磁微结构，其被配置为在一个或多个内表面限定的空隙的至少一部分内产生时不变的磁场。 在一个实施方案中，所述多个铁磁微结构中的至少一个包括与其连接的一个或多个靶向部分。
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73.发明申请Systems, devices, methods, and compositions including selectively accessible ferromagnetic structures 审中-公开包括可选择性可接受的铁磁结构的系统，装置，方法和组合物公开(公告)号：US20100303731A1
公开(公告)日：2010-12-02
申请号：US12455302
申请日：2009-05-29
IPC分类号： A61K49/06
CPC分类号： A61K49/1818
摘要： Magnetic resonance systems, devices, methods, and compositions are provided. A nuclear magnetic resonance imaging composition includes, but is not limited to, a plurality of ferromagnetic microstructures configured to generate a time-invariant magnetic field within at least a portion of one or more internal surface-defined voids. In an embodiment, a plurality of ferromagnetic microstructures includes one or more selectively accessible ferromagnetic microstructures.
摘要翻译： 提供了磁共振系统，装置，方法和组合物。 核磁共振成像组合物包括但不限于多个铁磁微结构，其被配置为在一个或多个内表面限定的空隙的至少一部分内产生时不变的磁场。 在一个实施例中，多个铁磁微结构包括一个或多个可选择性的铁磁微结构。
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74.发明申请Multiplex imaging systems, devices, methods, and compositions including ferromagnetic structures 有权多重成像系统，装置，方法和组合物，包括铁磁结构公开(公告)号：US20100301857A1
公开(公告)日：2010-12-02
申请号：US12455299
申请日：2009-05-29
CPC分类号： G01R33/5601 , G01R33/448 , H01F1/0308 , H01F1/06 , H01F41/0273
摘要： Multiplex imaging systems, devices, methods, and compositions are provided. A nuclear magnetic resonance imaging composition includes, but is not limited to, a plurality of ferromagnetic microstructures configured to generate a time-invariant magnetic field within at least a portion of one or more internal surface-defined voids.
摘要翻译： 提供了多重成像系统，装置，方法和组合物。 核磁共振成像组合物包括但不限于多个铁磁微结构，其被配置为在一个或多个内表面限定的空隙的至少一部分内产生时不变的磁场。
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公开(公告)号：US09443061B2
公开(公告)日：2016-09-13
申请号：US13199046
申请日：2011-08-16
申请人： Roderick A. Hyde , Jordin T. Kare , Wayne R. Kindsvogel , Royce A. Levien , Erez Lieberman , Mark A. Malamud , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, Jr.
发明人： Roderick A. Hyde , Jordin T. Kare , Wayne R. Kindsvogel , Royce A. Levien , Erez Lieberman , Mark A. Malamud , Nathan P. Myhrvold , Elizabeth A. Sweeney , Clarence T. Tegreene , Charles Whitmer , Lowell L. Wood, Jr.
CPC分类号： G06F19/3456 , G06F19/00 , G16H10/60
摘要： Embodiments disclosed herein relate to methods, devices, and computer systems thereof for visibly or non-visibly indicating a subject has received a medical treatment. In certain embodiments, a subject receives an information mark in conjunction with a medical treatment. In certain embodiments, the information mark includes unique information relating to the subject. In certain embodiments, devices, computer systems, and methods relate to reading an information mark on a subject, and optionally determining if further medical treatment of the subject is warranted. In certain embodiments, receipt of an information mark entitles a subject to a reward.
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公开(公告)号：US09314523B2
公开(公告)日：2016-04-19
申请号：US12924212
申请日：2010-09-21
CPC分类号： A61K41/0028 , A61K31/74 , A61M31/002
摘要： Disclosed herein include embodiments related to compositions, devices, computer systems, computer-implemented methods, and computer program products associated with an ingestible salt grabber.
摘要翻译： 本文公开了与组合物，装置，计算机系统，计算机实现的方法以及与可摄入盐捕获器相关联的计算机程序产品相关的实施例。
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公开(公告)号：US20120070380A1
公开(公告)日：2012-03-22
申请号：US12924212
申请日：2010-09-21
CPC分类号： A61K41/0028 , A61K31/74 , A61M31/002
摘要： Disclosed herein include embodiments related to compositions, devices, computer systems, computer-implemented methods, and computer program products associated with an ingestible salt grabber.
摘要翻译： 本文公开了与组合物，装置，计算机系统，计算机实现的方法以及与可摄入盐捕获器相关联的计算机程序产品相关的实施例。
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公开(公告)号：US20120034155A1
公开(公告)日：2012-02-09
申请号：US12806006
申请日：2010-08-03
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Wayne R. Kindsvogel , Gary L. McKnight , Elizabeth A. Sweeney , Lowell L. Wood, JR.
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Wayne R. Kindsvogel , Gary L. McKnight , Elizabeth A. Sweeney , Lowell L. Wood, JR.
IPC分类号： A61K51/00 , A61K39/00 , A61K49/00 , A61P37/04 , C07K19/00 , A61K39/395 , B82Y15/00 , B82Y5/00
CPC分类号： A61K35/18 , A61K39/00 , A61K41/0071 , A61K47/6901 , A61K49/0002 , A61K2039/515 , A61K2039/5154 , A61K2039/5156 , A61K2039/55516 , A61K2039/55555 , A61K2039/605 , C12N5/0006 , C12N5/0641
摘要： The present disclosure relates to various embodiments associated with artificial cells, particularly artificial antigen presenting cells, methods of making the same, methods of administering the same, computer systems relating thereto, computer-implemented methods relating thereto, and associated computer program products.
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公开(公告)号：US20110092961A1
公开(公告)日：2011-04-21
申请号：US12806008
申请日：2010-08-03
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Wayne R. Kindsvogel , Gary L. McKnight , Elizabeth A. Sweeney , Lowell L. Wood, JR.
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Wayne R. Kindsvogel , Gary L. McKnight , Elizabeth A. Sweeney , Lowell L. Wood, JR.
CPC分类号： A61K35/18 , A61K39/00 , A61K41/0071 , A61K47/6901 , A61K49/0002 , A61K2039/515 , A61K2039/5154 , A61K2039/5156 , A61K2039/55516 , A61K2039/55555 , A61K2039/605 , C12N5/0006 , C12N5/0641
摘要： The present disclosure relates to various embodiments associated with artificial cells, particularly artificial antigen presenting cells, methods of making the same, methods of administering the same, computer systems relating thereto, computer-implemented methods relating thereto, and associated computer program products.
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公开(公告)号：US20110086004A1
公开(公告)日：2011-04-14
申请号：US12947957
申请日：2010-11-17
申请人： Wayne R. Kindsvogel , Steven D. Hughes , Richard D. Holly , Christopher H. Clegg , Donald C. Foster , Rebecca A. Johnson , Mark D. Heipel , Pallavur V. Sivakumar
发明人： Wayne R. Kindsvogel , Steven D. Hughes , Richard D. Holly , Christopher H. Clegg , Donald C. Foster , Rebecca A. Johnson , Mark D. Heipel , Pallavur V. Sivakumar
CPC分类号： C07K16/32 , A61K38/20 , A61K39/395 , A61K39/39558 , C07K16/2818 , C07K16/2896 , C07K2317/732 , A61K2300/00
摘要： Methods for treating cancer by co-administering a therapeutic monoclonal antibody with IL-21 are described. Exemplary monoclonal antibodies that can be used are rituximab, trastuzumab and anti-CTLA-4 antibodies. The enhanced antitumor of the combination therapy is particularly useful for patient populations that are recalcitrant to monoclonal therapy, relapse after treatment with monoclonal antibodies or where the enhanced IL-21 antitumor effect reduces toxicities associated with treatment using the monoclonal antibodies.
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