公开(公告)号：US5998445A

公开(公告)日：1999-12-07

申请号：US679473

申请日：1996-07-09

申请人： Shigeru Souda ,  Norihiro Ueda ,  Shuhei Miyazawa ,  Katsuya Tagami ,  Seiichiro Nomoto ,  Makoto Okita ,  Naoyuki Shimomura ,  Toshihiko Kaneko ,  Masatoshi Fujimoto ,  Manabu Murakami ,  Kiyoshi Oketani ,  Hideaki Fujisaki ,  Hisashi Shibata ,  Tsuneo Wakabayashi

发明人： Shigeru Souda ,  Norihiro Ueda ,  Shuhei Miyazawa ,  Katsuya Tagami ,  Seiichiro Nomoto ,  Makoto Okita ,  Naoyuki Shimomura ,  Toshihiko Kaneko ,  Masatoshi Fujimoto ,  Manabu Murakami ,  Kiyoshi Oketani ,  Hideaki Fujisaki ,  Hisashi Shibata ,  Tsuneo Wakabayashi

IPC分类号： A61K31/44 ,  A61K31/4427 ,  A61K31/443 ,  A61K31/54 ,  A61P1/04 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14

CPC分类号： C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14

摘要： Pyridine derivatives useful for preventing or treating peptic ulcers, pharmaceutical preparations and methods of treating peptic ulcers are described.

摘要翻译： 描述了可用于预防或治疗消化性溃疡的吡啶衍生物，药物制剂和治疗消化性溃疡的方法。

公开(公告)号：US5708013A

公开(公告)日：1998-01-13

申请号：US524109

申请日：1995-08-21

申请人： Shigeru Souda ,  Norihiro Ueda ,  Shuhei Miyazawa ,  Katsuya Tagami ,  Seiichiro Nomoto ,  Makoto Okita ,  Naoyuki Shimomura ,  Toshihiko Kaneko ,  Masatoshi Fujimoto ,  Manabu Murakami ,  Kiyoshi Oketani ,  Hideaki Fujisaki ,  Hisashi Shibata ,  Tsuneo Wakabayashi

发明人： Shigeru Souda ,  Norihiro Ueda ,  Shuhei Miyazawa ,  Katsuya Tagami ,  Seiichiro Nomoto ,  Makoto Okita ,  Naoyuki Shimomura ,  Toshihiko Kaneko ,  Masatoshi Fujimoto ,  Manabu Murakami ,  Kiyoshi Oketani ,  Hideaki Fujisaki ,  Hisashi Shibata ,  Tsuneo Wakabayashi

IPC分类号： C07D401/12 ,  A61K31/44

CPC分类号： C07D401/12

摘要： A pyridine compound having the formula is disclosed and useful to treat the peptic ulcer. ##STR1## wherein R.sup.1 and R.sup.2 which may be the same or different are each a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogenated lower alkyl group, or a halogen atom, R.sup.3 and R.sup.4 which may be the same or different are each a hydrogen atom or a lower alkyl group, X is a group represented by the formula --S--, a group represented by the formula ##STR2## or a group represented by the formula ##STR3## and n is an integer of 1 to 6, provided that R.sup.3 and R.sup.4 are not simultaneously hydrogen atoms when n is 1.

摘要翻译： 公开了具有下式的吡啶化合物，可用于治疗消化性溃疡。 其中可以相同或不同的R 1和R 2各自为氢原子，低级烷基，低级烷氧基，卤代低级烷基或卤素原子，可以相同的R 3和R 4， 不同的是氢原子或低级烷基，X是由式-S-表示的基团，即由式d表示的基团，当n为1时，R3和R4不同时为氢原子。

公开(公告)号：US5527948A

公开(公告)日：1996-06-18

申请号：US402569

申请日：1995-03-13

申请人： Makoto Okita ,  Hiroshi Shirota ,  Masayuki Tanaka ,  Toshihiko Kaneko ,  Katsuya Tagami ,  Shigeki Hibi ,  Yasushi Okamoto ,  Seiichiro Nomoto ,  Takeshi Suzuki ,  Kenichi Chiba ,  Masaki Goto ,  Ryoichi Hashida ,  Hideki Ono ,  Hideto Ohhara ,  Hideki Sakurai ,  Shigeru Souda ,  Yoshimasa Machida ,  Kouichi Katayama ,  Isao Yamatsu

发明人： Makoto Okita ,  Hiroshi Shirota ,  Masayuki Tanaka ,  Toshihiko Kaneko ,  Katsuya Tagami ,  Shigeki Hibi ,  Yasushi Okamoto ,  Seiichiro Nomoto ,  Takeshi Suzuki ,  Kenichi Chiba ,  Masaki Goto ,  Ryoichi Hashida ,  Hideki Ono ,  Hideto Ohhara ,  Hideki Sakurai ,  Shigeru Souda ,  Yoshimasa Machida ,  Kouichi Katayama ,  Isao Yamatsu

IPC分类号： C07C39/225 ,  C07C43/215 ,  C07C43/23 ,  C07C43/30 ,  C07C43/313 ,  C07C43/315 ,  C07C45/00 ,  C07C45/29 ,  C07C45/30 ,  C07C45/51 ,  C07C45/54 ,  C07C45/59 ,  C07C45/63 ,  C07C45/71 ,  C07C47/57 ,  C07C47/575 ,  C07C49/83 ,  C07C49/84 ,  C07C59/68 ,  C07C69/157 ,  C07F7/18 ,  C07C69/76 ,  C07C49/115

CPC分类号： C07F7/1852 ,  C07C39/225 ,  C07C43/215 ,  C07C43/23 ,  C07C43/30 ,  C07C43/313 ,  C07C43/315 ,  C07C45/00 ,  C07C45/298 ,  C07C45/30 ,  C07C45/305 ,  C07C45/513 ,  C07C45/54 ,  C07C45/59 ,  C07C45/63 ,  C07C45/71 ,  C07C47/57 ,  C07C47/575 ,  C07C49/83 ,  C07C49/84 ,  C07C59/68

摘要： Naphthalene derivatives of the formula: ##STR1## wherein R.sup.1, represents a hydrogen atom, a lower alkyl group or an acyl group; R.sup.2 independently represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom, a cycloalkyl group, a cycloalkylalkyl group, a hydroxyl group, an aryl group which may be substituted, an arylalkyl group whose aryl group may be substituted, a heteroaryl group, or a heteroaryllakyl group; R.sup.3 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group, an aryl group which may have a substituent, an arylalkyl group whose aryl group may be substituted, an arylalkenyl group whose aryl group may be substituted, a cycloalkyl group, an alkoxyalkyl group, a heteroaryl group, a heteroarylalkyl group, a carboxyl group, a carboxyalkyl group, an aminoalkyl group, or a cyano group; R.sup.6 is C.sub.1-6 alkyl; and m is 0 or an integer of from 1 to 2 useful in treating autoimmune diseases are disclosed.

摘要翻译： 下式的萘衍生物：其中R 1，表示氢原子，低级烷基或酰基; R2独立地表示氢原子，低级烷基，低级烷氧基，卤素原子，环烷基，环烷基烷基，羟基，可被取代的芳基，芳基可以被取代的芳基烷基 ，杂芳基或杂芳基烷基; R 3表示氢原子，低级烷基，低级烯基，可以具有取代基的芳基，可以被取代芳基的芳基烷基，可以被芳基取代的芳基烯基，环烷基， 烷氧基烷基，杂芳基，杂芳基烷基，羧基，羧基烷基，氨基烷基或氰基; R6是C1-6烷基; 并且公开了m为0或可用于治疗自身免疫性疾病的1〜2的整数。

公开(公告)号：US5251690A

公开(公告)日：1993-10-12

申请号：US699608

申请日：1991-05-14

申请人： Katsumoto Otake ,  Yoshio Sumiya ,  Yasuo Fujitani ,  Shigeo Oda ,  Tokunori Matsushima ,  Takuya Sasaki ,  Keizo Ishida ,  Hideki Kon ,  Hiroshi Satoh ,  Toshihiko Kaneko ,  Makoto Yanagihara

发明人： Katsumoto Otake ,  Yoshio Sumiya ,  Yasuo Fujitani ,  Shigeo Oda ,  Tokunori Matsushima ,  Takuya Sasaki ,  Keizo Ishida ,  Hideki Kon ,  Hiroshi Satoh ,  Toshihiko Kaneko ,  Makoto Yanagihara

IPC分类号： F28G1/12

CPC分类号： F28G1/12

摘要： An apparatus for collecting cleaning bodies in a tubular heat exchanger capable of collecting the cleaning bodies with a high collection efficiency against the temporary introduction of a large amount foreign matter such as falling tools in a cooling water system and against the deflected flow of the cooling water from the upstream side. A rectifying member rectifies or regulates the deflected flow of the cooling water from the upstream side whereby it is possible to collect the cleaning bodies without any adhesion and stagnation of the cleaning bodies in the cooling water on V-shaped collection lattices. It is also possible to trap a large article such as a falling tool between a guide member disposed downstream of the collection lattices and the collection lattices, and to introduce only the cleaning bodies into the guide member. Furthermore, the downstream port of a cleaning body discharge pipe opens toward the downstream side to thereby prevent the clogging of the port with the foreign matter or the like.

公开(公告)号：US5089035A

公开(公告)日：1992-02-18

申请号：US457279

申请日：1989-12-27

申请人： Toshihiko Kaneko

发明人： Toshihiko Kaneko

IPC分类号： B01D53/26

CPC分类号： B01D53/261

摘要： A dehumidifier for removing moisture contained in air upon discharging the air which has been introducing from outside, comprises a container body, a meshed receptacle which is suspended through a receiving mouth formed on top of the container body and accommodates therein a deliquescent moisture absorbent, and a cover which covers the top end of the container body excluding the receiving mouth. On the top end of the container body, there are provided a receiving tube which is suspended therein and the bottom portion of a battery chamber. In the cover, there are provided an air sending tube which forms a vent passage together with the receiving tube being located within the receiving tube and is suspended lower than the receiving tube and a cover which forms the battery chamber together with the bottom portion of the battery chamber of the container body. Further, on the top of the air sending tube, a fan and its driving source are provided. The fan is driven so that the flow of air is introduced either from the receiving tube to the vent passage or vice versa through the container body interior, depending on the rotating direction of the driving source. The air introduced into the container body interior is dehumidified, and the dehumidified air is sent outside. When the level of deliquescence stored within the container body reaches the bottom end of the air sending tube, the vent passage is closed to stop the flow of air.

摘要翻译： 用于除去从外部排出的空气排出的空气中含有的湿气的除湿器包括容器主体，网状容器，其通过形成在容器主体顶部的容纳口悬挂并容纳潮溶性吸湿剂，并且 覆盖容器主体的除接收口以外的顶端的盖。 在容器主体的顶端设置有一个悬挂在其中的接收管和电池室的底部。 在盖子中，设置有一个空气送出管，它与容纳管一起形成一个通气通道，该接收管位于接收管内，并被悬挂在比接收管低的位置，并且一个与电池室的底部一起形成的盖子 容器体的电池室。 此外，在送风管的顶部设置有风扇及其驱动源。 风扇被驱动，使得空气流从接收管通过容器主体内部，从驱动源的旋转方向通过容器主体内部被引入到通风通道。 引入容器主体内部的空气被除湿，除湿空气被送到室外。 当储存在容器主体内的潮解度达到送​​风管的底端时，关闭排气通道以阻止空气流动。