公开(公告)号：US07731662B2

公开(公告)日：2010-06-08

申请号：US11917466

申请日：2006-07-25

申请人： Tor C. Anderson ,  Jiayu Chen ,  Shih-Ping Wang

发明人： Tor C. Anderson ,  Jiayu Chen ,  Shih-Ping Wang

IPC分类号： A61B8/14

CPC分类号： A61B8/0825 ,  A61B8/406 ,  A61B8/4218 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/483

摘要： An apparatus and related methods for ultrasonically scanning a tissue sample are described, the apparatus comprising an ultrasound transducer and a taut fabric sheet compressing the tissue sample, the ultrasound transducer contacting the taut fabric sheet and ultrasonically scanning the tissue sample therethrough. Preferably, the taut fabric sheet is substantially porous with respect to an acoustic couplant. In another embodiment, an ultrasound transducer and a vented membrane are provided, the vented membrane having a first surface contacting the tissue surface and a second surface opposite the first surface, the ultrasound transducer contacting the second surface and being translated across the second surface for ultrasonically scanning the tissue volume. An acoustic couplant is applied to one of the tissue surface, the first surface, and the second surface, the vented membrane being provided with a void pattern such that it is substantially porous with respect to the acoustic coupling agent.

摘要翻译： 描述了用于超声扫描组织样本的装置和相关方法，所述装置包括超声换能器和压缩组织样本的拉紧织物片，超声波换能器接触拉紧的织物片并且超声扫描组织样本。 优选地，拉紧织物片材相对于声耦合剂基本上是多孔的。 在另一个实施例中，提供超声换能器和通气膜，所述排气膜具有接触组织表面的第一表面和与第一表面相对的第二表面，超声波换能器接触第二表面并且跨越第二表面被翻转超声波 扫描组织体积。 将声耦合剂施加到组织表面，第一表面和第二表面中的一个，通气膜具有空隙图案，使得其相对于声耦合剂基本上是多孔的。

公开(公告)号：US20100063396A1

公开(公告)日：2010-03-11

申请号：US11917466

申请日：2006-07-25

申请人： Tor C. Anderson ,  Jiayu Chen ,  Shih-Ping Wang

发明人： Tor C. Anderson ,  Jiayu Chen ,  Shih-Ping Wang

IPC分类号： A61B8/14

CPC分类号： A61B8/0825 ,  A61B8/406 ,  A61B8/4218 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/483

摘要： An apparatus and related methods for ultrasonically scanning a tissue sample are described, the apparatus comprising an ultrasound transducer and a taut fabric sheet compressing the tissue sample, the ultrasound transducer contacting the taut fabric sheet and ultrasonically scanning the tissue sample therethrough. Preferably, the taut fabric sheet is substantially porous with respect to an acoustic couplant. In another embodiment, an ultrasound transducer and a vented membrane are provided, the vented membrane having a first surface contacting the tissue surface and a second surface opposite the first surface, the ultrasound transducer contacting the second surface and being translated across the second surface for ultrasonically scanning the tissue volume. An acoustic couplant is applied to one of the tissue surface, the first surface, and the second surface, the vented membrane being provided with a void pattern such that it is substantially porous with respect to the acoustic coupling agent.

摘要翻译： 描述了用于超声扫描组织样本的装置和相关方法，所述装置包括超声换能器和压缩组织样本的拉紧织物片，超声波换能器接触拉紧的织物片并且超声扫描组织样本。 优选地，拉紧织物片材相对于声耦合剂基本上是多孔的。 在另一个实施例中，提供超声换能器和通气膜，所述排气膜具有接触组织表面的第一表面和与第一表面相对的第二表面，超声波换能器接触第二表面并且跨越第二表面被翻转超声波 扫描组织体积。 将声耦合剂施加到组织表面，第一表面和第二表面中的一个，通气膜具有空隙图案，使得其相对于声耦合剂基本上是多孔的。

公开(公告)号：US07556602B2

公开(公告)日：2009-07-07

申请号：US10160836

申请日：2002-05-31

申请人： Shih-Ping Wang ,  Donald Chin ,  Fangyi Rao

发明人： Shih-Ping Wang ,  Donald Chin ,  Fangyi Rao

IPC分类号： A61B8/00

CPC分类号： A61B6/463 ,  A61B6/4423 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B8/0825 ,  A61B8/406 ,  A61B8/462 ,  A61B8/463 ,  A61B8/464 ,  A61B8/465 ,  A61B8/467 ,  A61B8/469 ,  A61B8/5238 ,  A61B8/565 ,  G06F19/00

摘要： Ultrasound mammography in which an automated transducer scans the patient's breast to generate many images of thin slices that are processed into few images of thick slices that can be displayed simultaneously for practical rapid assessment of the breast. The thin-slice images can be acquired by a technician so that a physician need only spend time in assessing the few displayed thick-slice images and, possibly, only a few of the thin-slice images that might match a suspected anomaly indicated in the thick-slice images. Computer-aided detection or diagnosis (CAD) can be performed on the images and resulting mark and/or other information can be displayed as well. Vibration images can be obtained as well and similarly processed and displayed to highlight abnormalities or for other reasons.

摘要翻译： 超声乳腺摄影术，其中自动换能器扫描患者的乳房以产生薄片的许多图像，其被加工成可以同时显示以用于乳房的实际快速评估的厚片的少数图像。 薄片图像可以由技术人员获取，使得医生仅需要花费时间来评估少数显示的厚片图像，并且可能仅花费少量可能匹配疑似异常的薄片图像 厚片图像。 可以对图像执行计算机辅助检测或诊断（CAD），并且可以显示所得到的标记和/或其他信息。 也可以获得振动图像，并进行相似的处理和显示，以突显异常或其他原因。

公开(公告)号：US07103205B2

公开(公告)日：2006-09-05

申请号：US10305661

申请日：2002-11-27

申请人： Shih-Ping Wang ,  Fangyi Rao

发明人： Shih-Ping Wang ,  Fangyi Rao

IPC分类号： G06K9/00

CPC分类号： A61B8/0825 ,  A61B6/463 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B8/406 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/463 ,  A61B8/464 ,  A61B8/465 ,  A61B8/467 ,  A61B8/5238 ,  A61B8/565 ,  G06F19/00 ,  Y10S128/916

摘要： An adjunctive ultrasound mammography system and associated methods are described in which an ultrasound image being displayed near an x-ray mammogram image may be superimposed thereon or thereunder by a user for facilitating rapid comprehension of breast structures and detection of abnormalities therein. In one preferred embodiment, the x-ray mammogram image corresponds to a standard x-ray mammogram view, and the ultrasound image is a thick-slice image representing a thick-slice or slab-like portion of the breast volume substantially parallel to that standard x-ray mammogram view. In another preferred embodiment, the user is permitted to manually manipulate the registration of the ultrasound image with the x-ray mammogram image. It has been found that the manual registration process, which involves manual vernier adjustments responsive to perceived registration differences, can rapidly increase the radiologist's perception of the breast structures being displayed by both component images. Even though ultrasound images tend to have substantially different textures and feature emphases than x-ray images, the bimodal thick-slice/x-ray image, alone or in conjunction with the vernier registration process, can often expose or clarify tissue structures hidden in the separate component images, and can often obviate or explain certain noticed structures in the component images.

摘要翻译： 描述了一种辅助超声乳腺摄影系统及其相关方法，其中在X射线乳房X线照相图像附近显示的超声图像可以由用户叠加在其上或其上，以便于快速理解乳房结构并检测其中的异常。 在一个优选实施例中，X射线乳房X线照相图像对应于标准x射线乳房X线照片视图，超声图像是表示基本上平行于该标准的乳房体积的厚切片或板状部分的厚片图像 x射线乳房X线照片视图。 在另一个优选实施例中，允许用户用X射线乳腺X线照片图像手动地操作超声图像的登记。 已经发现，手动注册过程涉及响应于感知到的注册差异的手动游标调整，可以快速增加放射科医师对由两个分量图像显示的乳房结构的感知。 尽管超声图像倾向于具有与x射线图像相比具有显着不同的纹理和特征的重点，但双峰厚片/ X射线图像单独或与游标注册过程一起可以经常暴露或澄清隐藏在 单独的组件图像，并且经常可以避免或解释组件图像中的某些注意结构。

公开(公告)号：US06574357B2

公开(公告)日：2003-06-03

申请号：US09946209

申请日：2001-09-05

申请人： Shih-Ping Wang

发明人： Shih-Ping Wang

IPC分类号： G06K900

CPC分类号： H05G1/60 ,  A61B6/465 ,  G06F3/0481 ,  G06F3/04855 ,  G06F2203/04805 ,  G06T5/50 ,  G06T7/0012 ,  G06T15/08 ,  G06T2207/10116 ,  G06T2207/30068 ,  G16H50/20

摘要： A computer-aided diagnostic (CAD) method and system provide image annotation information that can include an assessment of the probability, likelihood or predictive value of the CAD-detected suspected abnormalities as an additional aid to the radiologist. More specifically, probability values, in numerical form and/or analog form, are added to the locational markers of the CAD-detected suspected abnormalities. The task of a physician using a CAD system is believed to be made easier by displaying two different markers representing different probability thresholds. An additional threshold can be used to display “extra view markers” as an additional aid or guide to the radiologic technician to take extra views of a patient before the patient is released or discharged. A control device is added to allow the user to select and vary the probability threshold for the display of locational markers.

公开(公告)号：US4104516A

公开(公告)日：1978-08-01

申请号：US763638

申请日：1977-01-28

申请人： Shih-Ping Wang ,  Charles D. Robbins ,  Elisha Merritt

发明人： Shih-Ping Wang ,  Charles D. Robbins ,  Elisha Merritt

IPC分类号： H01J31/50

CPC分类号： H01J31/50 ,  H01J2231/50036

摘要： A panel shaped, proximity type, x-ray image intensifier tube for medical x-ray fluoroscopy use having all linear components and yet a high brightness gain, in excess of 4,000 cd-sec/m.sup.2 -R, the tube being comprised of a rugged metallic tube envelope, an inwardly concave metallic input window, a directly viewable full size output display screen, and a scintillator-photocathode screen having a thickness of at least 200 microns for a high x-ray photon utilization ability as well as x-ray stopping power, the scintillator-photocathode screen being suspended on insulators within the envelope and in between the input window and the output screen. The scintallator-photocathode screen is spaced from the output screen by at least 8mm to allow the application of a high negative potential at the scintillator-photocathode screen with respect to the output screen for high gain with low field emission, since all of the remaining components within the tube envelope are at neutral potential with respect to the output display screen.

摘要翻译： 用于医疗x射线荧光透视术的面板形接近型x射线图像增强管使用具有超过4,000cd / sec-m-R-R的所有线性分量和高亮度增益，该管由坚固的 金属管外壳，向内凹入的金属输入窗口，可直接观看的全尺寸输出显示屏幕和具有至少200微米厚度的闪烁体 - 光电阴极屏幕，用于高X射线光子利用能力以及X射线停止 电源，闪烁体 - 光电阴极屏幕悬挂在封套内的绝缘体上以及输入窗口和输出屏幕之间。 闪烁器 - 光电阴极屏幕与输出屏幕间隔至少8mm，以允许相对于输出屏幕在闪烁体 - 光电阴极屏幕处施加高负电位，用于具有低场发射的高增益，因为所有剩余部件 在管壳内相对于输出显示屏处于中性电位。

公开(公告)号：US10381557B2

公开(公告)日：2019-08-13

申请号：US16062414

申请日：2016-12-14

申请人： Shih-Yuan Wang ,  Shih-Ping Wang

发明人： Shih-Yuan Wang ,  Shih-Ping Wang

IPC分类号： H01L27/10 ,  H01L27/24 ,  H01L45/00

摘要： Resistive RAM (RRAM) devices having increased reliability and related manufacturing methods are described. Greater reliability of RRAM cells over time can be achieved by avoiding direct contact of metal electrodes with the device switching layer. The contact can be avoided by cladding the switching layer in a material such as silicon or using electrodes that may contain metal but have regions that are adjacent the switching layer and lack free metal ions except for possible trace amounts.

公开(公告)号：US09647036B2

公开(公告)日：2017-05-09

申请号：US15010450

申请日：2016-01-29

申请人： Shih-Yuan Wang ,  Shih-Ping Wang

发明人： Shih-Yuan Wang ,  Shih-Ping Wang

IPC分类号： H01L45/00 ,  H01L27/24

CPC分类号： H01L27/2409 ,  H01L27/2481 ,  H01L27/249 ,  H01L45/06 ,  H01L45/08 ,  H01L45/1226 ,  H01L45/1233 ,  H01L45/1253 ,  H01L45/144 ,  H01L45/146 ,  H01L45/1608 ,  H01L45/1633 ,  H01L45/165

摘要： Resistive RAM (RRAM) devices having increased uniformity and related manufacturing methods are described. Greater uniformity of performance across an entire chip that includes larger numbers of RRAM cells can be achieved by uniformly creating enhanced channels in the switching layers through the use of radiation damage. The radiation, according to various described embodiments, can be in the form of ions, electromagnetic photons, neutral particles, electrons, and ultrasound.

公开(公告)号：US09468367B2

公开(公告)日：2016-10-18

申请号：US14400986

申请日：2013-05-14

申请人： Xiaolong Ouyang ,  Paul D. Indman ,  Robert K. Deckman ,  Shih-Ping Wang

发明人： Xiaolong Ouyang ,  Paul D. Indman ,  Robert K. Deckman ,  Shih-Ping Wang

IPC分类号： A61B1/00 ,  A61B1/04 ,  A61B1/06 ,  A61B1/307 ,  A61B1/303 ,  A61B1/05 ,  A61B1/005 ,  A61B1/12 ,  A61B1/015

CPC分类号： A61B1/303 ,  A61B1/00006 ,  A61B1/00034 ,  A61B1/00052 ,  A61B1/00066 ,  A61B1/00071 ,  A61B1/00094 ,  A61B1/00103 ,  A61B1/00105 ,  A61B1/00114 ,  A61B1/00124 ,  A61B1/005 ,  A61B1/015 ,  A61B1/05 ,  A61B1/06 ,  A61B1/0676 ,  A61B1/0684 ,  A61B1/126 ,  A61B1/307

摘要： Instruments and methods are described for performing hysteroscopy and/or combined hysteroscopy and endometrial biopsy. According to some embodiments, the handle, electronics and integrated display screen form a re-usable portion of the instrument while the fluid hub and cannula which includes a CMOS imaging module and LED lighting, form a single use portion of the instrument. The cannula is semi-flexible such that the operator can easily grasp the cannula at some intermediate point along the shaft (e.g. 5 inches from the distal tip) to bend and/or steer the cannula during use. According to some embodiments, the distal tip has a larger diameter than the shaft which has been found to improve fluid management during use in some applications.

摘要翻译： 描述了用于进行宫腔镜检查和/或组合宫腔镜检查和子宫内膜活检的仪器和方法。 根据一些实施例，当包括CMOS成像模块和LED照明的流体轮毂和套管形成仪器的单个使用部分时，手柄，电子和集成显示屏幕形成仪器的可重复使用的部分。 套管是半柔性的，使得操作者可以容易地沿着轴的某个中间点（例如距离远侧尖端5英寸）抓住套管，以在使用期间弯曲和/或引导套管。 根据一些实施例，远侧末端具有比轴更大的直径，已经被发现在一些应用中在使用期间改善流体管理。

公开(公告)号：US08721552B2

公开(公告)日：2014-05-13

申请号：US13489091

申请日：2012-06-05

申请人： Tor C. Anderson ,  Jiayu Chen ,  Shih-Ping Wang

发明人： Tor C. Anderson ,  Jiayu Chen ,  Shih-Ping Wang

IPC分类号： A61B8/00

CPC分类号： A61B8/0825 ,  A61B8/406 ,  A61B8/4218 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/483

摘要： Automated ultrasonic scanning of a chestwardly compressed breast of a supine patient uses a scanning assembly that moves down to compress the breast through a membrane that is secured to the assembly across a bottom opening. A motorized ultrasound transducer moves across the breast while the breast remains downwardly compressed against the patient's chest, sending and receiving ultrasound energy through the membrane. The membrane is porous with respect to an acoustic coupling liquid that impregnates it. The transducer outputs ultrasound information that is processed to form initial planar images and then reconstructed slice images of breast tissue.

摘要翻译： 仰卧患者胸部压缩乳房的自动超声波扫描使用向下移动的扫描组件，以通过穿过底部开口固定到组件的膜来压缩乳房。 电动超声波换能器穿过乳房，同时乳房保持向下压迫患者的胸部，通过膜发送和接收超声能量。 相对于浸渍它的声耦合液体，膜是多孔的。 传感器输出被处理以形成初始平面图像，然后重建乳腺组织切片图像的超声信息。