摘要:
The present invention provides novel, long-acting nanoformulated drugs and targeted drug delivery methods, and uses thereof. In one embodiment, the nanoformulated drug is a retroviral drug. In one embodiment, the nanoformulated composition comprises a nanocarrier with one or more incorporated drugs. In an exemplary embodiment, the drug is efavirenz (EFV). In a further embodiment, the nanocarrier is associated with an agent for targeting microfold cells (M-cells). In a specific embodiment, the targeting agent binds to an M-cell marker known as glycoprotein 2 (GP2). Via this mechanism, the nanodrug is targeted toward GALT.
摘要:
A method and apparatus for handover between base stations are disclosed. The method includes: a first base station sending handover request messages to neighboring base stations (401); the neighboring base stations judging whether to accept the handover according to information in the handover request messages, and sending judgment results to the first base station through request response messages (402); the first base station determining one destination base station from the neighboring base stations which are able to accept the handover, and sending a confirmation handover message to the destination base station (403); the destination base station allocating resources for a user equipment after receiving the confirmation handover message, and sending the allocated resources to the first base station through a confirmation handover response message (404); and the first base station indicating that the user equipment hands over to the destination base station after receiving the confirmation handover response message (405).
摘要:
The present invention provides for a resin system and coating composition suitable for direct application to metal substrates. The composition may include a phosphate functional polyester. The polyester may be an unsaturated polyester polyol. The coating composition may further include a suitable curing agent, such as an isocyanate or melamine. The composition can be applied through traditional application equipment onto a variety of metal substrates and cures to an acceptable surface for further processing, such as top coating with basecoat and clearcoat.
摘要:
The present invention provides for a metal coating composition that includes a resin system with at least one unsaturated polyester polyol and a curing agent such as an isocyanate or a melamine. The compositions are suitable as a primer and provide good adhesion and moisture resistance to metal substrates.
摘要:
The present invention provides for a resin system and coating composition suitable for direct application to metal substrates. The composition may include a phosphate functional polyester. The polyester may be an unsaturated polyester polyol. The coating composition may further include a suitable curing agent, such as an isocyanate or melamine. The composition can be applied through traditional application equipment onto a variety of metal substrates and cures to an acceptable surface for further processing, such as top coating with basecoat and clearcoat.
摘要:
A pigment dispersing polymer comprising a backbone having one or more urea groups and having polymeric side chains extending therefrom. The dispersing polymer may be formed from the reaction of a compound having one or more carbodiimide groups with acid functional resins such as acid functional polyesters, acid functional acrylics, acid functional polyethers, and fatty acids.
摘要:
A method of transmitting and receiving an audio/video data, and a method of communication between a first mobile communication apparatus and a second mobile communication apparatus using audio/video data are provided. An audio/video data to be transmitted is selected via the first mobile communication apparatus. Next, the audio/video data is transformed into at least one data packet via the first mobile communication apparatus based on a permitted data flow specified by PHS. Next, the packet data is transmitted via the first communication apparatus. Thereafter, the data packet is received via the second mobile communication apparatus where the data packet is transformed into the audio/video data.
摘要:
Compositions and methods for treating substrates are disclosed. The compositions are generally described as epoxy-novolac resins containing a Mannich derivatized bisphenol side chain. The methods, which comprise contacting the surface to be treated with these compositions, improve the corrosion resistance and/or adhesion properties of the treated surface.