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    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS
    72.
    发明申请
    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS 审中-公开

    公开(公告)号：US20170270268A1

    公开(公告)日：2017-09-21

    申请号：US15606743

    申请日：2017-05-26

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

    IPC: G06F19/00 ,  G06F19/28

    Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

    METHOD AND SYSTEM FOR CHARACTERIZING SKIN RELATED CONDITIONS
    74.
    发明申请
    METHOD AND SYSTEM FOR CHARACTERIZING SKIN RELATED CONDITIONS 审中-公开

    公开(公告)号：US20170228514A1

    公开(公告)日：2017-08-10

    申请号：US15497072

    申请日：2017-04-25

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Jessica Richman ,  Catalina Valdivia ,  Daniel Almonacid

    IPC: G06F19/00 ,  G06F19/28 ,  C12Q1/68 ,  G06F19/24

    CPC classification number: G06F19/3418 ,  C12Q1/6874 ,  G06F19/00 ,  G06F19/24 ,  G06F19/28 ,  G16H50/20 ,  Y02A90/26

    Abstract: Embodiments of a method and system for characterizing a skin-related condition in relation to a user can include one or more of: a handling network operable to collect containers comprising material from a set of users, the handling network comprising a sequencing system operable to determine microorganism sequences from sequencing the material; a microbiome characterization system operable to: determine at least one of microbiome composition data and microbiome functional diversity data based on the microorganism sequences, collect supplementary data associated with the skin-related condition for the set of users, and transform the supplementary data and the at least one of the microbiome composition data and the microbiome functional diversity data into a characterization model; and a therapy system operable to promote a treatment to the user for the skin-related condition based on characterizing the user with the characterization model in relation to the skin-related condition.

    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR LOCOMOTOR SYSTEM CONDITIONS
    76.
    发明申请
    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR LOCOMOTOR SYSTEM CONDITIONS 审中-公开
    用于定位系统条件的微生物衍生诊断和治疗方法和系统

    公开(公告)号：US20160259909A1

    公开(公告)日：2016-09-08

    申请号：US15098222

    申请日：2016-04-13

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman ,  Siavosh Rezvan Behbahani

    IPC: G06F19/00 ,  G06F19/12

    CPC classification number: G06F19/3418 ,  G16B20/00 ,  G16B50/00 ,  G16H20/00 ,  G16H50/50 ,  Y02A50/57 ,  Y02A90/26

    Abstract: A method for at least one of characterizing, diagnosing, and treating a locomotor system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the locomotor system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the locomotor system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

    Abstract translation: 一种至少一种在至少一个受试者中表征，诊断和治疗运动系统状况的方法，所述方法包括：从受试者群体接收聚集的一组生物样品; 为受试者群体生成微生物组合数据集和微生物群功能分集数据集中的至少一个; 基于从至少一个微生物组合数据集和微生物组合功能分集数据集提取的特征，产生运动系统状况的表征; 基于所述表征，产生被配置为校正所述运动系统状况的治疗模型; 并且在与受试者相关联的输出装置处，基于表征和治疗模型促进对受试者的治疗。

    METHOD AND SYSTEM FOR MICROBIOME-DERIVED CHARACTERIZATION, DIAGNOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH FUNCTIONAL FEATURES
    77.
    发明申请
    METHOD AND SYSTEM FOR MICROBIOME-DERIVED CHARACTERIZATION, DIAGNOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH FUNCTIONAL FEATURES 审中-公开
    用于与功能特征相关的条件的微生物衍生特征，诊断和治疗方法和系统

    公开(公告)号：US20160228003A1

    公开(公告)日：2016-08-11

    申请号：US15098110

    申请日：2016-04-13

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman ,  Siavosh Rezvan Behbahani

    IPC: A61B5/00 ,  G06F19/00 ,  C12Q1/68 ,  G06F19/12 ,  G06F19/28

    CPC classification number: A61B5/0022 ,  A61B5/4836 ,  C12Q1/689 ,  C12Q2600/112 ,  G06F19/3418 ,  G16B40/00 ,  G16B50/00 ,  G16H40/67 ,  G16H50/20 ,  G16H50/80 ,  Y02A90/24 ,  Y02A90/26

    Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

    Abstract translation: 用于至少一种表征，诊断和治疗与至少一个受试者中的产生微生物体的功能特征相关的病症的方法，所述方法包括：从受试者群体接收聚集的一组生物样品; 为受试者群体生成微生物组合数据集和微生物群功能分集数据集中的至少一个; 基于从至少一个微生物组合数据集和微生物组合功能分集数据集中提取的特征产生条件的表征; 基于所述表征，产生被配置为校正所述状况的治疗模型; 并且在与受试者相关联的输出装置处，基于表征和治疗模型促进对受试者的治疗。

    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH MICROBIOME TAXONOMIC FEATURES
    78.
    发明申请
    METHOD AND SYSTEM FOR MICROBIOME-DERIVED DIAGNOSTICS AND THERAPEUTICS FOR CONDITIONS ASSOCIATED WITH MICROBIOME TAXONOMIC FEATURES 审中-公开
    用微生物衍生的诊断方法和系统和与微生物特征特征相关的条件的治疗方法

    公开(公告)号：US20160224749A1

    公开(公告)日：2016-08-04

    申请号：US15098174

    申请日：2016-04-13

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman ,  Siavosh Rezvan Behbahani

    IPC: G06F19/00 ,  A61B5/00 ,  C12Q1/68 ,  G06F19/12 ,  G06F19/28

    CPC classification number: A61B5/4211 ,  A61B5/4233 ,  A61B5/4836 ,  A61B5/4839 ,  C12Q1/689 ,  C12Q2600/112 ,  G06F19/00 ,  G06F19/24 ,  G06F19/28 ,  G06F19/3418 ,  G16H50/20 ,  G16H50/70 ,  Y02A90/26

    Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome taxonomic features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

    Abstract translation: 用于表征，诊断和治疗与至少一个受试者中的微生物组分类特征有关的病症中的至少一种的方法，所述方法包括：从受试者群体接收聚集的一组生物样品; 为受试者群体生成微生物组合数据集和微生物群功能分集数据集中的至少一个; 基于从至少一个微生物组合数据集和微生物组合功能分集数据集中提取的特征产生条件的表征; 基于所述表征，产生被配置为校正所述状况的治疗模型; 并且在与受试者相关联的输出装置处，基于表征和治疗模型促进对受试者的治疗。

    Method and system for diagnostic testing
    79.
    发明授权
    Method and system for diagnostic testing 有权

    公开(公告)号：US10415105B2

    公开(公告)日：2019-09-17

    申请号：US15198818

    申请日：2016-06-30

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid

    IPC: G01N33/48 ,  C12Q1/70 ,  A61B10/00 ,  C12Q1/689 ,  G06G7/58

    Abstract: An embodiment of a method for diagnostic testing includes: providing a sampling kit to a subject, the sampling kit including a sample container for reception of a sample from a collection site of the subject; receiving the sample from the subject; generating a microbiome sequence dataset based upon sequencing nucleic acid content of a microorganism portion of the sample; detecting a presence of a set of microbiome targets; generating a diagnostic analysis based on the detected set of microbiome targets; generating a therapy recommendation based on the set of microbiome targets; and promoting the therapy recommendation in coordination with presenting information derived from the diagnostic analysis.

    Method and system for microbiome-derived diagnostics and therapeutics for locomotor system conditions
    80.
    发明授权
    Method and system for microbiome-derived diagnostics and therapeutics for locomotor system conditions 有权

    公开(公告)号：US10409955B2

    公开(公告)日：2019-09-10

    申请号：US15098222

    申请日：2016-04-13

    Applicant: uBiome, Inc.

    Inventor： Zachary Apte ,  Daniel Almonacid ,  Jessica Richman ,  Siavosh Rezvan Behbahani

    IPC: G01N33/48 ,  G06F19/00 ,  G16B20/00 ,  G16B50/00 ,  G06G7/58

    Abstract: A method for at least one of characterizing, diagnosing, and treating a locomotor system condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the locomotor system condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the locomotor system condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.

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