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245 条记录 (耗时 0.028 秒)

    Method and instruments for stretching skin grafts
    72.
    发明授权
    Method and instruments for stretching skin grafts 失效
    皮肤移植物的方法和仪器

    公开(公告)号：US06364908B1

    公开(公告)日：2002-04-02

    申请号：US09284544

    申请日：1999-08-04

    申请人： Willem Marie Ysebaert

    发明人： Willem Marie Ysebaert

    IPC分类号： A61B1708

    CPC分类号： A61B17/322 ,  A61B90/02 ,  A61B2017/306 ,  A61B2017/3225 ,  Y10S623/909

    摘要： A method for spreading skin grafts, wherein the skin grafts are placed on an elastic membrane, after which the membrane is stretched in at least two directions substantially perpendicular to each other and the skin grafts present on the membrane are spread. A spreading means, a stretcher and a membrane to be used therewith, as well as to a method for applying skin grafts to a burn.

    摘要翻译： 一种用于铺展皮肤移植物的方法，其中将皮肤移植物放置在弹性膜上，然后将膜在基本上彼此垂直的至少两个方向上拉伸，并且存在于膜上的皮肤移植物被扩散。 铺展手段，担架和使用的膜，以及将皮肤移植物施用于烧伤的方法。

    Hernia mesh
    73.
    发明授权
    Hernia mesh 失效
    疝网

    公开(公告)号：US06319264B1

    公开(公告)日：2001-11-20

    申请号：US09054672

    申请日：1998-04-03

    申请人： Pertti Törmälä ,  Senja Paasimaa ,  Teuvo Antikainen

    发明人： Pertti Törmälä ,  Senja Paasimaa ,  Teuvo Antikainen

    IPC分类号： A61B1708

    CPC分类号： D04B21/12 ,  A61F2/0063 ,  A61F2210/0004 ,  A61F2250/003 ,  A61L31/148 ,  D10B2509/08

    摘要： According to the present invention, a flexible, fibrous hernia mesh is provided, which is intended to be implanted to close hernia defects. The mesh has at least two functional components or layers: (1) a rapidly degradable first layer and (2) a more slowly degradable (with respect to the first layer) second layer. Using the fibrous mesh of this invention, the hernia defect can be closed so that a) the second layer supports the area until the scar tissue is strong enough (around 6 months), to prevent recurrent hernia formation, b) while the more rapid degradation of the first layer induces scar tissue formation due to inflammatory reaction, and c) the second layer isolates the first layer from the abdominal cavity, preventing tissue to tissue adhesion onto the intestines. The mesh is placed on the uncovered fascia area with its more rapidly absorbable side (the first layer) towards the fascia.

    摘要翻译： 根据本发明，提供了一种柔性的纤维疝网，其旨在植入以闭合疝气缺陷。 网格具有至少两个功能性组分或层：（1）可快速降解的第一层和（2）相对于第一层更缓慢地降解的第二层。 使用本发明的纤维网，可以关闭疝缺损，使得a）第二层支撑该区域，直到瘢痕组织足够强（约6个月），以防止复发性疝气形成，b）当更快速降解时 的第一层由于炎症反应而引起瘢痕组织形成，c）第二层将第一层与腹腔隔离，防止组织粘附到肠上。 将网格放置在未覆盖的面筋区域上，其更易吸收的侧面（第一层）朝向筋膜。

    Devices and methods for percutaneous mitral valve repair
    74.
    发明授权
    Devices and methods for percutaneous mitral valve repair 失效
    用于经皮二尖瓣修复的装置和方法

    公开(公告)号：US06312447B1

    公开(公告)日：2001-11-06

    申请号：US09417945

    申请日：1999-10-13

    申请人： Randall Y. Grimes

    发明人： Randall Y. Grimes

    IPC分类号： A61B1708

    CPC分类号： A61B17/00234 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/0682 ,  A61B2017/00243 ,  A61B2017/00783 ,  A61B2017/00867 ,  A61B2017/0647 ,  A61B2017/0649 ,  A61B2017/306

    摘要： Devices and methods are provided for diagnosing and repairing mitral valve defects such as mitral valve regurgitation. According to an exemplary method, mitral valve function is visualized by transesophageal echocardiography. A catheter (10) is inserted along the venous system of the patient through the left and right atria (a, b) into the mitral valve (26). A suction tip (25) grasps the leaflets (28, 30) of the mitral valve (26) to immobilize and juxtapose the leaflets (28, 30) at a point simulating a stitch, and the mitral valve (26) is again observed to confirm that fastening at that point will repair the prolapse or other defect. The mitral valve leaflets (28, 30) are then fastened together via a fastener such as a staple (44) or shape memory rivet (44). The fastener (44) may be inserted by a stapling assembly (40) in the catheter (10), or by a separate stapler (40) that is inserted along an arterial path from the opposite direction and guided along a transcardiac rail to the immobilized point. Upon completion of the repair process, the mitral valve (26) is once again visualized by transesophageal echocardiography to determine whether repair thereof has been effected.

    摘要翻译： 设备和方法用于诊断和修复二尖瓣缺损如二尖瓣反流。 根据示例性方法，通过经食管超声心动图显示二尖瓣功能。 沿着患者的静脉系统将导管（10）通过左右心房（a，b）插入二尖瓣（26）中。 抽吸尖端（25）抓住二尖瓣（26）的小叶（28,30），以在模拟针迹的点处固定和并置传单（28,30），并且二尖瓣（26）再次被观察到 确认紧固在那一点将修复脱垂或其他缺陷。 然后通过诸如钉（44）或形状记忆铆钉（44）的紧固件将二尖瓣小叶（28,30）紧固在一起。 紧固件（44）可以通过缝合组件（40）插入到导管（10）中，或者通过单独的订书机（40）插入，该订书机沿相反方向沿着动脉途径插入，并沿着经心脏导轨被导向固定 点。 在完成修复过程之后，通过经食管超声心动图再次显示二尖瓣（26），以确定其修复是否已经实现。

    Apparatus and method for closing a septal defect
    75.
    发明授权
    Apparatus and method for closing a septal defect 有权
    闭合中隔缺损的装置和方法

    公开(公告)号：US06312446B1

    公开(公告)日：2001-11-06

    申请号：US09659346

    申请日：2000-09-12

    申请人： Joseph Huebsch ,  Paul J. Buscemi ,  Thomas J. Holman ,  Danney Langanki

    发明人： Joseph Huebsch ,  Paul J. Buscemi ,  Thomas J. Holman ,  Danney Langanki

    IPC分类号： A61B1708

    CPC分类号： A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00619 ,  A61B2017/00623

    摘要： A catheter delivered device to close a septal defect, the device comprising a cylindrical shaft of metal or polymeric material with concentric parallel cuts through the wall of the device which create flattened support struts. The center of the support struts move radially away from the axis in a hinge like fashion in response to the movement of the device's proximal and distal ends toward the center of the device. This movement is reversibly effected through mechanical means. The device can be coated with growth factors, mitogenic factors or other determinants which can improve tissue growth such that tissue ingrowth can occur over a period of time. The catheter itself may be an ultrasonic imaging catheter.

    摘要翻译： 导管输送装置以闭合隔膜缺损，该装置包括金属或聚合材料的圆柱形轴，穿过穿过该装置的壁的同心平行切口，其形成平坦的支撑支柱。 响应于装置的近端和远端朝向装置的中心的移动，支撑支柱的中心以铰链相似的方式径向地远离轴线移动。 这种运动通过机械手段可逆地实现。 该装置可以涂覆生长因子，促有丝分裂因子或其它决定因素，其可以改善组织生长，使得组织向内生长可以在一段时间内发生。 导管本身可以是超声成像导管。

    Polyester/cyanoacrylate tissue adhesive formulations
    76.
    发明授权
    Polyester/cyanoacrylate tissue adhesive formulations 有权
    聚酯/氰基丙烯酸酯组织粘合剂配方

    公开(公告)号：US06299631B1

    公开(公告)日：2001-10-09

    申请号：US09439167

    申请日：1999-11-12

    申请人： Shalaby W. Shalaby

    发明人： Shalaby W. Shalaby

    IPC分类号： A61B1708

    CPC分类号： A61L24/043 ,  A61B17/00491 ,  A61B17/11 ,  C08L35/04 ,  C08L67/04

    摘要： The present invention is directed to bioabsorbable adhesive/hemostatic formulations of a 2-alkoxyalkylcyanoacrylate and liquid or solid polymeric modifiers and adjuvant. The present adhesive formulations are useful as tissue adhesive/sealants, hemostatic agents, and as a means for patching or anastomic coupling of damaged organs.

    摘要翻译： 本发明涉及2-烷氧基烷基氰基丙烯酸酯和液体或固体聚合物改性剂和佐剂的生物可吸收粘合剂/止血剂。 本发明的粘合剂制剂可用作组织粘合剂/密封剂，止血剂，以及作为受损器官的修补或吻合的手段。

    Method of catheterization and inhibition of arterial bleeding
    78.
    发明授权
    Method of catheterization and inhibition of arterial bleeding 失效
    导管插入术和抑制动脉出血的方法

    公开(公告)号：US06287323B1

    公开(公告)日：2001-09-11

    申请号：US09203426

    申请日：1998-12-01

    申请人： Julius G. Hammerslag

    发明人： Julius G. Hammerslag

    IPC分类号： A61B1708

    CPC分类号： A61B17/00491 ,  A61B17/0057 ,  A61B17/02 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61B2017/00654 ,  A61B2017/00659

    摘要： Disclosed is a device for delivering tissue adhesives and/or sealant patches to a surface which covers or surrounds a perforation in a lumen, cavity or organ, or potential lumen or cavity, within a human or other animal. Also disclosed is a method of delivering tissue adhesives and/or sealant patches to a surface which covers or surrounds a lumen, cavity or organ, or potential lumen or cavity. The method is particularly suited to sealing perforations in vascular walls, such as after arterial access for Percutaneous Transluminal Coronary Angioplasty (PTCA), Percutaneous Coronary Angiography and Percutaneous Coronary Atherectomy and other diagnostic and therapeutic procedures.

    摘要翻译： 公开了一种用于将组织粘合剂和/或密封剂贴片递送到覆盖或围绕人或其他动物内的腔，空腔或器官或潜在的内腔或空腔中的穿孔的表面的装置。 还公开了一种将组织粘合剂和/或密封剂贴片递送到覆盖或围绕内腔，空腔或器官或潜在的内腔或空腔的表面的方法。 该方法特别适用于密封血管壁中的穿孔，例如在经皮腔内冠状动脉血管成形术（PTCA），经皮冠状动脉造影术和经皮冠状动脉粥样硬化斑块切除术等动脉通路之后进行其他诊断和治疗手术。

    Anastomosis apparatus for use in intraluminally directed vascular anastomosis
    80.
    发明授权
    Anastomosis apparatus for use in intraluminally directed vascular anastomosis 失效
    用于内膜定向血管吻合术的吻合装置

    公开(公告)号：US06248117B1

    公开(公告)日：2001-06-19

    申请号：US09293617

    申请日：1999-04-16

    申请人： Duane D. Blatter

    发明人： Duane D. Blatter

    IPC分类号： A61B1708

    CPC分类号： A61B17/115 ,  A61B17/0684 ,  A61B17/072 ,  A61B17/3403 ,  A61B2017/00243 ,  A61B2017/00252 ,  A61B2017/07214 ,  A61B2017/1107 ,  A61B2017/1135

    摘要： The present invention relates to new and useful apparatus for use with an intraluminally directed anvil apparatus for intraluminally directed vascular anastomosis of an end of a graft vessel to the wall of a receiving blood vessel that is performed according to a minimally invasive procedure. The intraluminally directed vascular anastomosis does not require the interruption of blood flow in the receiving blood vessel and it is versatile enough to suitably combine a variety of cutting, welding, soldering, sealing, and joining techniques such as stapling. The intraluminally directed anvil apparatus comprises an anvil and a wire used for signaling the optimal anastomosis site; this signaling can be performed when the initial exploration is performed. The intraluminally directed anvil apparatus is typically used with a catheter.

    摘要翻译： 本发明涉及一种新的和有用的装置，其用于与根据微创程序进行的接受血管的壁的移植血管的端部的腔内定向的砧座装置进行腔内定向的血管吻合。 腔内定向的血管吻合不需要接收血管中的血流中断，并且其通用性足以适当地组合各种切割，焊接，焊接，密封和接合技术，例如缝合。 经内镜定向的砧设备包括用于发信号通知最佳吻合部位的砧和线; 当执行初始探查时，可以执行该信令。 通常使用经导管的砧座装置与导管一起使用。