Eye phantom for evaluating retinal angiography image

    公开(公告)号:US12011223B2

    公开(公告)日:2024-06-18

    申请号:US17280284

    申请日:2019-10-08

    CPC classification number: A61B3/0025 A61B3/102 A61B3/1241

    Abstract: The present invention relates to an eye phantom for evaluating a retinal angiography image, and a manufacturing method therefor. A purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, capable of simulating even the vascular structure and blood flow of a retina so as to be more similar to an actual retinal structure than a conventional eye phantom; and a manufacturing method therefor. More specifically, a purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, including various shapes of fine fluid channel structures corresponding to the vascular structure formed in an actual retina; and a manufacturing method therefor.

    METHOD AND APPARATUS FOR MEASURING MAGNETIC FIELD AND TEMPERATURE USING DIAMOND NITROGEN VACANCY SENSOR

    公开(公告)号:US20240168106A1

    公开(公告)日:2024-05-23

    申请号:US17991087

    申请日:2022-11-21

    CPC classification number: G01R33/032 G01R33/0017 G01R33/0082

    Abstract: Disclosed is a method and apparatus for measuring magnetic field and/or temperature using a diamond nitrogen-vacancy center sensor, and a measuring apparatus based on a diamond nitrogen-vacancy center (DNV) sensor may include: a diamond nitrogen-vacancy center sensor; a frequency synthesizer for generating a first reference signal and a second reference signal; a first microwave generator for generating a first microwave that is frequency modulated according to the first reference signal and causes a first spin transition in the diamond nitrogen-vacancy center sensor; a second microwave generator for generating a second microwave that is frequency modulated according to the second reference signal and causes a second spin transition in the diamond nitrogen-vacancy center sensor; a laser irradiator for applying a laser to excite the spin state of the diamond nitrogen-vacancy center sensor; a power amplifier for combining and amplifying the first microwave and the second microwave to apply to the diamond nitrogen-vacancy center sensor; a detector for detecting a fluorescence signal output from the diamond nitrogen-vacancy center sensor; a reference detector for measuring power of the laser; a differential circuit for outputting the difference between an output signal of the detector and an output signal of the reference detector; a first lock-in amplifier for outputting a result of comparing an output of the differential circuit with the first reference signal, and a second lock-in amplifier for outputting a result of comparing an output of the differential circuit with the second reference signal. Using the apparatus, it is possible to remove an influence of the temperature when measuring the magnetic field, and remove an influence of a change in the magnetic field when measuring the temperature, thereby enabling more precise measurement.

    GRADIENT-INDEX PHONONIC CRYSTAL FLAT LENS AND DESIGN METHOD FOR SAME

    公开(公告)号:US20230360629A1

    公开(公告)日:2023-11-09

    申请号:US17777465

    申请日:2020-11-11

    CPC classification number: G10K11/30 G02B1/005 G10K11/24

    Abstract: A gradient-index phononic crystal flat lens which controls the behavior of an acoustic wave having a designated frequency. The gradient-index phononic crystal flat lens may include one or more super cells each having a plurality of layers stacked in a vertical direction according to a target gradient index profile, wherein each of the layers is composed of an aggregate in which unit cells having scatterers formed with the same size in the centers thereof are arranged in a horizontal direction. The one or more super cells may each include a divider provided between the neighboring layers, and configured to force the acoustic wave to propagate in the horizontal direction within the gradient-index phononic crystal flat lens.

    Liquid immersion micro-channel measurement device and measurement method which are based on trapezoidal incident structure prism incident-type silicon

    公开(公告)号:US11719624B2

    公开(公告)日:2023-08-08

    申请号:US16464792

    申请日:2016-12-15

    Abstract: The present invention relates to a liquid immersion micro-channel measurement device and measurement method which are based on trapezoidal incident structure prism incident-type silicon, and according to one embodiment of the present invention, the liquid immersion micro-channel measurement device based on trapezoidal incident structure prism incident-type silicon comprises: a micro-channel structure including a support and at least one micro-channel, which is formed on the support and has a sample detection layer to which a first bioadhesive material for detecting a first sample is fixed; a quadrangular pyramid-shaped prism formed on the upper part of the micro-channel structure; a sample injection unit for injecting, into the micro-channel, a buffer solution containing the first sample; a polarized light generation unit for emitting incident light polarized through the prism on the micro-channel at an incident angle that satisfies a p-wave non-reflection condition; and a polarized light detection unit for detecting, from the polarized incident light, a polarization change in a first refection light reflected from the sample detection layer, wherein the prism completely reflects, from the polarized incident light incident on the prism, on an upper boundary surface of the prism, second reflection light reflected from a lower boundary surface of the prism and a boundary surface of the buffer solution injected into the micro-channel.

    Flat-Plate Focusing Ultrasonic Transducer and Acoustic Lens Which are Composed of Annular Array Piezoelectric Element, and Methods of Manufacturing and Designing Thereof

    公开(公告)号:US20220241818A1

    公开(公告)日:2022-08-04

    申请号:US17325669

    申请日:2021-05-20

    Abstract: The present invention relates to a flat-plate focusing ultrasonic transducer and an acoustic lens composed of an annular array piezoelectric element and methods of manufacturing and designing thereof, more particularly to a flat-plate focusing ultrasonic transducer composed of an annular array piezoelectric element, wherein the annular array piezoelectric element has a plurality of concentric regions which is concentrically arranged in a concentric circle shape with respect to a center point, the concentric region has ring shaped sound insulation regions and piezoelectric regions which are alternatively formed in a direction from the center point to a radius direction, so as to focus a sound wave near a focal point, wherein the piezoelectric regions are composed of a piezoelectric ring that is composed of a piezoelectric material and thus excites a sound wave, the concentric region is in a shape of a flat-plate of which both sides are flat and which has a constant thickness, and each radius of the plurality of the sound insulation regions and the piezoelectric regions in the concentric region are calculated based on a set focal length of the ultrasonic transducer and a frequency of a set sound wave.

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