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    SYSTEMS AND METHODS FOR REMOVING REVERBERATION FROM AUDIO SIGNALS
    86.
    发明申请
    SYSTEMS AND METHODS FOR REMOVING REVERBERATION FROM AUDIO SIGNALS 审中-公开

    公开(公告)号：US20190172477A1

    公开(公告)日：2019-06-06

    申请号：US16271338

    申请日：2019-02-08

    Applicant: The University of Rochester

    Inventor： Mark Bocko ,  Sarah Smith

    IPC: G10L21/0264 ,  G10L21/0232 ,  G10L21/0208

    Abstract: Disclosed herein are systems and methods for removing reverberation from signals. The systems and methods can be applicable to audio signals, for example, to voice, musical instrument sounds, and the like. Signals such as the vowel sounds in speech and the sustained portions of many musical instrument sounds can be composed of a fundamental frequency component and a series of harmonically related overtones. The systems and methods can exploit the intrinsically high degree of mutual correlation among the overtones. When such signals are passed through a reverberant channel, the degree of mutual correlation among the partials can be reduced. An inverse channel filter for the removal of reverberation can be found by employing an adaptive filter technique that maximizes the cross-correlation among signal overtones.

    Apparatus and method for automatic alignment in an optical system and applications
    87.
    发明授权
    Apparatus and method for automatic alignment in an optical system and applications 有权

    公开(公告)号：US10123697B2

    公开(公告)日：2018-11-13

    申请号：US14482195

    申请日：2014-09-10

    Applicant: UNIVERSITY OF ROCHESTER

    Inventor： Ethan A. Rossi

    IPC: A61B3/12 ,  G02B21/00 ,  A61B3/10 ,  A61B3/00

    Abstract: Methods and apparatus for automatically aligning a confocal aperture utilize a confocal imaging system and a computer controlled optimization algorithm such as the Nelder-Mead algorithm for imaging an in-vivo eye having chromatic aberration. When using a confocal aperture of 3.4 Airy disks in diameter, images were obtained using retinal radiant exposures of less than 2.44 J/cm2, which is ˜22 times below the current ANSI maximum permissible exposure. The embodied method can be used, e.g., to study RPE morphology in AMD and other diseases, providing a powerful tool for understanding disease pathogenesis and progression, and offering a new means to assess the efficacy of treatments designed to restore RPE health.

    COMPOSITION AND METHODS FOR THE TREATMENT OF PERIPHERAL NERVE INJURY
    90.
    发明申请
    COMPOSITION AND METHODS FOR THE TREATMENT OF PERIPHERAL NERVE INJURY 审中-公开

    公开(公告)号：US20180256503A1

    公开(公告)日：2018-09-13

    申请号：US15976276

    申请日：2018-05-10

    Applicant: UNIVERSITY OF ROCHESTER

    Inventor： John Elfar ,  Kuang-Ching Tseng ,  Mark Noble

    IPC: A61K9/16 ,  A61K45/06 ,  A61K9/70 ,  A61K31/4409 ,  A61K47/34 ,  A61K9/00

    CPC classification number: A61K9/1647 ,  A61K9/0024 ,  A61K9/7007 ,  A61K31/4409 ,  A61K45/06 ,  A61K47/34

    Abstract: Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.

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