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    POWDER METALLURGY (PM) SUPERALLOY WITH HIGH STRENGTH AND PLASTICITY AND PREPARATION METHOD AND USE THEREOF
    81.
    发明申请
    POWDER METALLURGY (PM) SUPERALLOY WITH HIGH STRENGTH AND PLASTICITY AND PREPARATION METHOD AND USE THEREOF 有权

    公开(公告)号：US20230049935A1

    公开(公告)日：2023-02-16

    申请号：US17864207

    申请日：2022-07-13

    Applicant: Zhengzhou University of Aeronautics

    Inventor： Dejian SUN ,  Jiachen KANG ,  Guizhong Li ,  Ka GAO ,  Zan ZHANG ,  Yang GAO ,  Lei FAN ,  Xiaoqin GUO

    IPC: C22C19/05 ,  C22C19/07 ,  C22C1/04 ,  B22F3/03

    Abstract: The present disclosure discloses a preparation method of a powder metallurgy (PM) superalloy with high strength and plasticity. Under the multi-field coupling action of a thermal field and a force field, the PM superalloy is obtained in a high-temperature graphite mold by using the method of conducting heat preservation and oscillating-pressure sintering in two steps. Under the action of a circulating pressure, rearrangement of powders and discharge of pores are promoted, and therefore, the PM superalloy is sintered and formed. The present disclosure further discloses a PM superalloy prepared by using the method above. The PM superalloy has the characteristics of low grade of prior particle boundary defects, uniform grain refinement and high density. The sintered PM superalloy obtained in the present disclosure has a yield strength of 955 MPa, a tensile strength of 1,437 MPa and an elongation of 31.9%, and has high strength and plasticity.

    Medical Image Registration Method Based on Progressive Images
    82.
    发明申请
    Medical Image Registration Method Based on Progressive Images 有权

    公开(公告)号：US20220414903A1

    公开(公告)日：2022-12-29

    申请号：US17851066

    申请日：2022-06-28

    Applicant: Zhengzhou University of Light Industry

    Inventor： Erlin TIAN ,  Qian ZHENG ,  Jiaofen NAN ,  Xiao ZHANG ,  Weide LIANG

    IPC: G06T7/33 ,  G06T7/37 ,  G06T3/00 ,  G06V10/74

    Abstract: A two-stage medical image registration method based on progressive images (PIs) to solve the technical problem of low registration accuracy of traditional image registration methods includes: merging a reference image with a floating image to generate multiple intermediate PIs; registering, by a speeded-up robust features (SURF) algorithm and an affine transformation, the floating image with the intermediate PIs to acquire coarse registration results; registering, by the SURF algorithm and the affine transformation, the reference image with the coarse registration results to acquire fine registration results; and comparing the fine registration results of the intermediate PIs, which are acquired by iteration, and selecting an optimal registration result as a final registration image. The method can achieve multimodal registration for brain imaging with MI, NCC, MSD, and NMI superior to those of the existing registration algorithms. The method effectively improves the registration accuracy through the progressive medical image registration strategy.

    ANTI-ATOPIC DERMATITIS PROTEIN
    84.
    发明申请
    ANTI-ATOPIC DERMATITIS PROTEIN 有权

    公开(公告)号：US20220096595A1

    公开(公告)日：2022-03-31

    申请号：US17427109

    申请日：2020-03-30

    Applicant: ZHENGZHOU UNIVERSITY

    Inventor： Qiaozhen KANG ,  Xin LIU ,  Jike LU ,  Zhenyu JI ,  Ting WANG ,  Juanjuan YI ,  Chenglong ZHANG ,  Xun GUO

    IPC: A61K38/17 ,  A61P17/04

    Abstract: Provided is an anti-atopic dermatitis protein. A corresponding pharmaceutical composition contains a pharmaceutically acceptable carrier and the anti-atopic dermatitis protein. The anti-atopic dermatitis protein is one or more proteins selected from the group consisting of Helicobacter pylori-neutrophil-activating protein (HP-NAP) and recombinant maltose-binding protein fused to neutrophil-activating protein (rMBP-NAP). HP-NAP and rMBP-NAP can effectively treat AD in an oxazolone-induced AD model, providing brand-new drugs for the treatment of AD.

    NANOLASER BASED ON DEPTH-SUBWAVELENGTH GRAPHENE-DIELECTRIC HYPERBOLIC DISPERSIVE CAVITY
    85.
    发明申请
    NANOLASER BASED ON DEPTH-SUBWAVELENGTH GRAPHENE-DIELECTRIC HYPERBOLIC DISPERSIVE CAVITY 有权

    公开(公告)号：US20210344168A1

    公开(公告)日：2021-11-04

    申请号：US17098942

    申请日：2020-11-16

    Applicant: ZHENGZHOU UNIVERSITY OF AERONAUTICS

    Inventor： Yan LI ,  Facheng ZHONG ,  Yanyan WANG ,  Peng YANG ,  Kun XU ,  Pei DING ,  Fanguang ZENG

    IPC: H01S5/10 ,  H01S5/04

    Abstract: The disclosure provides a nanolaser based on a depth-subwavelength graphene-dielectric hyperbolic dispersive cavity, comprising a pumping light source and the depth-subwavelength graphene-dielectric hyperbolic dispersive cavity; wherein the depth-subwavelength graphene-dielectric hyperbolic dispersive cavity is a spherical or hemispherical hyperbolic dispersive microcavity formed by alternately wrapping a dielectric core with graphene layers and dielectric layers. Because the graphene plasmon has unique excellent performances, such as an electrical adjustability, a low intrinsic loss, a high optical field localization, and a continuously adjustable resonance frequency from mid-infrared to terahertz, compared with a common metal-dielectric hyperbolic dispersive characteristic, a graphene-dielectric hyperbolic dispersive metamaterial used by the disclosure not only may highly localize an energy of an electromagnetic wave in a more depth-subwavelength cavity, but also may reduce an ohmic loss and improve a quality factor.

    Method of Preparing Indium Oxide Spherical Powder With Controllable Grain Shape
    86.
    发明申请
    Method of Preparing Indium Oxide Spherical Powder With Controllable Grain Shape 有权

    公开(公告)号：US20210276879A1

    公开(公告)日：2021-09-09

    申请号：US15931269

    申请日：2020-05-13

    Applicant: Zhengzhou University

    Inventor： Jie CHEN ,  Jilin HE ,  Benshuang SUN ,  Yongchun SHU ,  Xueyun ZENG ,  Yang LIU

    IPC: C01G15/00

    Abstract: A method of preparing an indium oxide spherical powder with a controllable grain shape includes: (1) reacting a sulfuric acid solution, and then adding a nitric acid solution, to react with the metal indium to obtain a mixed solution system containing indium sulfate and indium nitrate; (2) adjusting a concentration of indium ions in the mixed solution system to between 0.45˜0.6M; (3) performing a precipitation reaction of the mixed solution with a precipitant, until a pH value of the solution is between 9-10, and then having the solution precipitated and aged to obtain an indium hydroxide precursor slurry; (4) using a ceramic membrane to filter and wash the precursor slurry, and ending the washing to obtain a purified precursor sample; (5) drying the precursor sample at 80˜130° C.; and (6) ball-milling the precursor sample, and calcining the precursor at a calcination temperature to obtain the indium oxide powder.

    ANDROGRAPHOLIDE COMPOUND AND METHOD FOR TREATMENT OR PREVENTION OF FIBROTIC DISEASE USING THE SAME
    87.
    发明申请
    ANDROGRAPHOLIDE COMPOUND AND METHOD FOR TREATMENT OR PREVENTION OF FIBROTIC DISEASE USING THE SAME 有权

    公开(公告)号：US20210047307A1

    公开(公告)日：2021-02-18

    申请号：US17009821

    申请日：2020-09-02

    Applicant: Zhengzhou University

    Inventor： Guifu DAI ,  Di WU ,  Haiwei XU ,  Jiazhen ZHU ,  Zibo FU ,  Zhenzhen GUAN ,  Xiaopei ZHANG ,  Ning SHANG ,  Shuqiu ZHANG ,  Guangming YAN

    IPC: C07D407/04 ,  C07D307/58 ,  A61P1/16 ,  A61P11/00 ,  A61P13/12

    Abstract: A compound represented by formula I or II. R1 and R2 are at each occurrence selected from the group consisting of hydrogen, methyl, phenyl, 2-methoxyphenyl, 3-methoxyphenyl, 4-methoxyphenyl, 3,4,5-trimethoxyphenyl, 2-hydroxyphenyl, 3-hydroxyphenyl, 4-hydroxyphenyl, 2-fluorophenyl, 2-chlorophenyl, 2-bromophenyl, 3-fluorophenyl, 3-chlorophenyl, 3-bromophenyl, 4-fluorophenyl, 4-chlorophenyl, 4-bromophenyl, 2-fluoro-3-methoxyphenyl, 3-methoxy-4-chlorophenyl, 2,4-difluorophenyl, 2,4-dichlorophenyl, 2,4-dibromophenyl, 2-fluoro-4-chlorophenyl, 2-bromo-4-chlorophenyl, 3-fluoro-4-chlorophenyl, 3-bromo-4-chlorophenyl, 3,4-difluorophenyl, 3,4-dichlorophenyl, 3,4-dibromophenyl, 2-chloro-4-fluorophenyl, 2-bromo-4-fluorophenyl, 3-chloro-4-fluorophenyl, 3-bromo-4-fluorophenyl, 2-fluoro-4-bromophenyl, 2-chloro-4-bromobenzene group, 3-fluoro-4-bromophenyl, 3-chloro-4-bromophenyl, 2,3,4-trichlorophenyl, 2-methoxy-4-chlorophenyl, 2-hydroxy-4-chlorophenyl, 2-hydroxy-4-methoxyphenyl, 3-fluoro-4-(4-methylpiperazinyl)phenyl, 4-(N,N-dimethylamino)phenyl, and 3-fluoro-4-(4-morpholinyl)phenyl. R3 and R4 are hydrogen, or R3 and R4 are at each occurrence selected from the group consisting of —CH2CH2COOH, —CH2CH2CH2CH2COOH, —CH2CH═CHCH2COOH, and —CH2CH2CH2CH2CH2CH2CH2COOH; or R3 and R4 are —COR5, and R5 is selected from the group consisting of 3-pyridyl, —CH2CH2COOH, —CH2CH2CH2CH2COOH, —CH2CH═CHCH2COOH, and —CH2CH2CH2CH2CH2CH2CH2COOH.

    Pipeline radar and television inspection robot
    88.
    发明申请
    Pipeline radar and television inspection robot 有权

    公开(公告)号：US20210010628A1

    公开(公告)日：2021-01-14

    申请号：US17030404

    申请日：2020-09-24

    Applicant: Zhengzhou University ,  WELEAD Infrastructure Engineering Technology (Zhengzhou), Ltd.

    Inventor： Hongyuan Fang ,  Peng Zhao ,  Bin Li ,  Jianwei Lei ,  Chengchao Guo ,  Yanhui Pan ,  Haijun Li ,  Wei Wu ,  Zongsheng Lu

    IPC: F16L55/40 ,  F16L55/32 ,  B25J5/00 ,  E21B4/16

    Abstract: The present application discloses a pipeline radar and television inspection robot which includes a robot body, a directional drilling lifting device, a directional drilling rotary device, a directional drilling swing device, a radar, cameras and a driving apparatus; wherein the directional drilling lifting device is on a front part of the robot body; the directional drilling rotary device is on the directional drilling lifting device; the directional drilling swing device is on the directional drilling rotary device; the radar and the cameras are on the directional drilling swing device; the driving apparatus are on a bottom of the robot body. The directional drilling lifting device, the radar and the cameras are plugged in the robot body. The robot body electrically connects to cables which electrically connect to a control system. The cameras and the radar are able to be adjusted and the components are connected as modules.

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