摘要:
A system for imaging of prostate cancer in a prostate in vivo is provided. The system utilizes Diffuse Optical Tomography (DOT) for creating a 3D image for the detection of suspicious prostate tissue. The DOT image may be used to guide the biopsy, thereby reducing the number of false negatives. A method, computer-readable medium and use are also provided.
摘要:
An optical scanning device for scanning an information carrier. The device includes an array optical element arranged to generate an array of radiation spots from an incident radiation beam, for the scanning of the information carrier. The device further includes an aberration optical element arranged to apply a predetermined optical aberration to the radiation for correction of optical aberration in the radiation spots.
摘要:
A system (10, 100, 300, 400) is provided for identifying certain targeted cells or tissues in a body. The system (10, 100, 300, 400) preferably includes at least one ingestible capsule that accommodates or supports (20) at least one of an illuminating module (30, 114, 322, 422, 452), a detecting module (40, 124, 324, 424, 434, 454), an imaging module (50, 326, 432, 456), a control module (60), or a reservoir (70, 132, 312, 412, 442) suitable for retaining and releasing one or more nanoshells. A method (200) is also provided for employing the system (10, 100, 300, 400) to detect, image or otherwise interact with diseased or abnormal cells and/or tissues in a body. The system (10, 100, 300, 400) and method (200) provided allow for improved diagnosing, treating and imaging techniques and for increased sensitivity and specificity in efficiently distinguishing targeted diseased or abnormal cells or tissue from surrounding healthy cells or tissue.
摘要:
An optical information medium (20) for recording, such as DVR-blue, and a method for manufacturing such a medium (20) is provided. Reading from and recording onto the medium (20) is performed by means of a focused radiation beam (10) having a radiation wavelength λ and a numerical aperture NA. Said medium has a substrate (1), and a stack (2) of layers provided thereon. The stack (2) comprises at least a first recording stack (3) and k radiation beam transmissive layers (4, 5). Each transmissive layer (4, 5) has a refractive index ni and an average thickness di μm and 1≦i≦k and k≧2. The thickness dk of layer k (5) is determined by a simple formula which depends on the parameters ni for i=1 . . . k and di for i=1 . . . k−1. Such a medium (20) has zero or substantially zero spherical aberration at the focal point, being at the recording layer of the first recording stack (3), of said radiation beam (10).
摘要翻译:提供了用于记录诸如DVR-blue的光学信息介质(20)和用于制造这种介质(20)的方法。 借助于具有辐射波长λ和数值孔径NA的聚焦辐射束(10)进行从介质(20)的读取和记录。 所述介质具有衬底(1)和设置在其上的层叠体(2)。 堆叠(2)至少包括第一记录堆叠(3)和k个辐射束透射层(4,5)。 每个透射层(4,5)具有折射率n i和平均厚度d i m i,并且1≤i≤k且k> = 2。 层k(5)的厚度d k k由一个简单的公式确定,该简单公式取决于i = 1的参数n i i i i i i i。 。 。 k和d i i i i = 1。 。 。 k-1。 这种介质(20)在位于所述辐射束(10)的第一记录叠层(3)的记录层处的焦点处具有零或基本为零的球面像差。
摘要:
An optical scanning device (1) for scanning an information layer (4) of an optical record carrier (2), the information layer (4) being covered by a transparent layer (3) of thickness td and refractive index nd. The device comprises a radiation source (11) for generating a radiation beam (12, 15, 20) and an objective system (18) for converging the radiation beam on the information layer. The objective system is characterised in comprising a lens comprising a synthetic resin on a substrate, the total thickness t of the lens satisfying the condition: Formula (I), where FWD+td/nd
摘要翻译:一种用于扫描光学记录载体(2)的信息层(4)的光学扫描装置(1),所述信息层(4)由厚度为t 1的透明层(3)覆盖, 和折射率n sub>。 该装置包括用于产生辐射束(12,15,20)的辐射源(11)和用于将辐射束会聚在信息层上的物镜系统(18)。 该目标系统的特征在于包括:在基板上包括合成树脂的透镜,满足以下条件的透镜的总厚度t:公式(I),其中FWD + t d <0.51,FWD是透镜(18)和载体(2)之间的自由工作距离,Phi是透镜(18)的入射光瞳直径,其中t,t < SUB>,Phi和FWD以毫米表示。
摘要:
A compound objective lens includes a first lens element and a second lens element, the first element including a mirror surface for internally redirecting a radiation beam passing through the first element. The objective lens has a numerical aperture greater than 0.65, and the focal length F1 of the first element is related to the focal length F of the objective lens by the relation: F 1 F > 2.5 .
摘要:
A device for reading and/or writing a record carrier (13), the device comprising converging means (35, 45, 47, 106, 108) for focusing a radiation beam (27, 101) originating from a radiation source (25) on the record carrier (13). The converging means comprises polarization means (103) and a diffraction grating (107) of birefringent material. Dependent on the direction of polarization, the radiation beam (101) is focused on one of two possible surfaces corresponding to DVD and DVR, respectively. A diffraction grating (107) is present in a central area of the radiation beam (101) and causes diffraction of a first order for one direction of polarization of the radiation beam (101) and diffraction of a second, higher, order for a second direction of polarization of the radiation beam (101). The diffraction grating (107) is made of birefringent material.
摘要:
An optical scanning device (1) for scanning an information layer (4) of an optical record carrier (2), the device including a radiation source (11) for generating a radiation beam (12) and an objective system (18) for converging the radiation beam (12) on the information layer, the objective system (18) being characterized in that the ratio of the root mean square of the optical path difference's (OPD's) generated by the objective system at oblique beam entrance to the system satisfies the condition of formula (I) within the field of the objective system, where OPD(A31) is the contribution of the third order Zernike coma to the root mean square wavefront aberration and OPD(A51) is the contribution of the fifth order Zernike coma to the root mean square wavefront aberration.
摘要:
An optical scanning device (1) for scanning an information layer (4) of an optical record carrier (2), the device (1) comprising a radiation source (11) for generating a radiation beam (12, 15, 20) and an objective system (18) for converging the radiation beam on the information layer, the information layer being covered by a transparent layer (3) of thickness td and refractive index nd. The objective system comprises a lens formed of a single material. The lens satisfies the condition: Fomula (I), where t is the thickness of the lens, FWD is the free working distance between the lens (18) and the carrier (2), where t, td and FWD are expressed in millimeters, and where FWD+td/nd
摘要:
A device for scanning a first and second type of optical record carriers (2; 40) generates a first and a second radiation beam for scanning the first and second type of record carriers, respectively, the first radiation beam having a first numerical aperture larger than the second numerical aperture of the second radiation beam. The device includes a non-periodic phase structure that does not affect the first radiation beam. The phase structure introduces an amount of spherical aberration in the second radiation beam for scanning the second type of record carriers for compensating the difference in spherical aberration required for scanning through the different thickness of the transparent layer (3; 41) of the first and second type of record carriers (2, 40). To reduce the amount of stray light on the detection system (25) from rays in the second radiation beam having a numerical aperture larger than the second numerical aperture, the phase grating introduces a discontinuity in the gradient of the wavefront deviation it introduces in the second radiation beam. The discontinuity allows spatial filtering in the plane of the detection system (25) of the desired and undesired rays of the second radiation beam.