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公开(公告)号：US08278340B2
公开(公告)日：2012-10-02
申请号：US12324346
申请日：2008-11-26
申请人： Christian Melander , John Cavanagh , David Ritchie , Robert W. Huigens, III , T. Eric Ballard , Justin J. Richards , Thomas W. Lindsey , Jonathan S. Lindsey
发明人： Christian Melander , John Cavanagh , David Ritchie , Robert W. Huigens, III , T. Eric Ballard , Justin J. Richards , Thomas W. Lindsey , Jonathan S. Lindsey
摘要： Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator.
摘要翻译： 提供了用于预防，去除或抑制植物或植物部分中的微生物生物膜形成或微生物感染的方法的公开，包括向其施用有效量的本文所述的活性化合物或其农业上可接受的盐。 还提供了增强杀微生物剂（例如包括铜，抗生素，噬菌体等）和/或植物防御活化剂的方法，包括施用如本文所述的活性化合物。 还提供了包含本文所述在农业上可接受的载体中的活性化合物的组合物，并且在一些实施方案中，组合物还包括杀微生物剂（例如包括铜，抗生素，噬菌体等）和/或植物防御活化剂。
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82.发明申请METHODS AND INTERMEDIATES FOR THE SYNTHESIS OF DIPYRRIN-SUBSTITUTED PORPHYRINIC MACROCYCLES 审中-公开二吡啶取代的磷杂环化合物的合成方法及其中间体公开(公告)号：US20120126214A1
公开(公告)日：2012-05-24
申请号：US13359668
申请日：2012-01-27
IPC分类号： H01L51/46 , G11C11/00 , C08G73/06 , C07D487/22 , C07F3/06
CPC分类号： H01L51/0077 , C07D403/06 , C07D403/14 , C07D487/22 , Y02E10/549 , Y02P70/521
摘要： The present invention provides dipyrrin substituted porphyrinic macrocycles, intermediates useful for making the same, and methods of making the same. Such compounds may be used for purposes including the making of molecular memory devices, solar cells and light harvesting arrays.
摘要翻译： 本发明提供二吡咯取代的卟啉大环化合物，可用于制备其的中间体及其制备方法。 这些化合物可用于包括制备分子记忆装置，太阳能电池和光收集阵列的目的。
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83.发明授权Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom 失效用于聚合和表面附着的取代苯并吡喃并吡嗪和由其形成的制品公开(公告)号：US08106393B2
公开(公告)日：2012-01-31
申请号：US13035157
申请日：2011-02-25
IPC分类号： H01L51/00
CPC分类号： C09B7/00
摘要： The present invention provides an article of manufacture formed from a substrate and a benzazoloporphyrazine bound to the substrate. The article may take a variety of different forms and may be for example an electrochromic display, a molecular capacitor, a battery, a solar cell, or a molecular memory device. Methods of making such articles, along with compounds, methods and intermediates useful for making such benzazoloporphyrazines, are also described.
摘要翻译： 本发明提供了由底物和与该底物结合的苯并唑并吡嗪形成的制品。 制品可以采用各种不同的形式，并且可以是例如电致变色显示器，分子电容器，电池，太阳能电池或分子存储器件。 还描述了制备这些制品的方法，以及可用于制备这种苯并唑啉吡嗪的化合物，方法和中间体。
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公开(公告)号：US07939656B2
公开(公告)日：2011-05-10
申请号：US12856020
申请日：2010-08-13
IPC分类号： C07B47/00 , C07D487/22
CPC分类号： C07D403/06 , C07D487/22
摘要： A method of making a compound of Formula I′ comprises reacting a compound of the formula DLCHO, with a compound of the formula to produce the compound of Formula I′. Methods of using the compounds are also described, particularly as intermediates for the synthesis of porphyrin rods, which porphyrin rods are in turn useful for (among other things) the production of molecular memory devices.
摘要翻译： 制备式I'化合物的方法包括使式DLCHO的化合物与下式的化合物反应以制备式I'的化合物。 还描述了使用化合物的方法，特别是作为合成卟啉棒的中间体，其中卟啉棒又可用于（尤其）分子存储装置的生产。
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85.发明授权Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom 失效用于聚合和表面附着的取代苯并吡喃并吡嗪和由其形成的制品公开(公告)号：US07919770B2
公开(公告)日：2011-04-05
申请号：US11447219
申请日：2006-06-05
IPC分类号： H01L35/24
CPC分类号： C09B7/00
摘要： The present invention provides an article of manufacture formed from a substrate and a benzazoloporphyrazine bound to the substrate. The article may take a variety of different forms and may be for example an electrochromic display, a molecular capacitor, a battery, a solar cell, or a molecular memory device. Methods of making such articles, along with compounds, methods and intermediates useful for making such benzazoloporphyrazines, are also described.
摘要翻译： 本发明提供了由底物和与该底物结合的苯并唑并吡嗪形成的制品。 制品可以采用各种不同的形式，并且可以是例如电致变色显示器，分子电容器，电池，太阳能电池或分子存储器件。 还描述了制备这些制品的方法，以及可用于制备这种苯并唑啉吡嗪的化合物，方法和中间体。
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86.发明申请公开(公告)号：US20110015388A1
公开(公告)日：2011-01-20
申请号：US11447219
申请日：2006-06-05
IPC分类号： C09B47/04
CPC分类号： C09B7/00
摘要： The present invention provides an article of manufacture formed from a substrate and a benzazoloporphyrazine bound to the substrate. The article may take a variety of different forms and may be for example an electrochromic display, a molecular capacitor, a battery, a solar cell, or a molecular memory device. Methods of making such articles, along with compounds, methods and intermediates useful for making such benzazoloporphyrazines, are also described.
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公开(公告)号：US20100204465A1
公开(公告)日：2010-08-12
申请号：US12693069
申请日：2010-01-25
申请人： Jonathan S. Lindsey , Masahiko Taniguchi , Doyoung Ra , Guoning Mo , Thiagarajan Balasubramanian
发明人： Jonathan S. Lindsey , Masahiko Taniguchi , Doyoung Ra , Guoning Mo , Thiagarajan Balasubramanian
IPC分类号： C07D487/22 , C07D403/06
CPC分类号： C07D207/33 , C07D207/335 , C07D207/34 , C07D207/46
摘要： A method of making chlorins comprises the steps of reacting (e.g. condensing) a dipyrrin western half intermediate with an eastern half intermediate to form a tetrahydrobilene, and then cyclizing the tetrahydrobilene to form a chlorin. Intermediates including tetrahydrobilenes useful in such reactions are also described.
摘要翻译： 制备二氢卟酚的方法包括使双吡啶西半中间体与东半中间体反应（例如缩合）以形成四氢苯乙烯的步骤，然后环化四氢苯并形成二氢卟酚。 还描述了包括在这种反应中有用的四氢噻吩的中间体。
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公开(公告)号：US07534807B2
公开(公告)日：2009-05-19
申请号：US11357833
申请日：2006-02-17
申请人： Han-Je Kim , Jonathan S. Lindsey
发明人： Han-Je Kim , Jonathan S. Lindsey
CPC分类号： C07D487/22 , C07D207/335 , C09B47/00 , G01N21/6486
摘要： A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
摘要翻译： 通过将一对式II化合物缩合以产生细菌二氢卟酚，其中R是缩醛或醛基，从而进行制备细菌生物素的方法。 缩合可以在有机溶剂中进行，优选在酸的存在下进行。 细菌二氢卟酚可用于各种目的，例如光动力疗法中的活性剂，流式细胞术中的发光化合物，太阳能电池，光收集阵列和分子存储装置。
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公开(公告)号：US20090075295A1
公开(公告)日：2009-03-19
申请号：US12095423
申请日：2006-11-30
申请人： Jonathan S. Lindsey
发明人： Jonathan S. Lindsey
CPC分类号： G01N33/582 , G01N21/643 , G01N21/6486 , G01N33/533 , G01N2021/6439 , Y02A50/53 , Y02A50/55 , Y02A50/57 , Y02A50/58 , Y10T436/145555
摘要： The present invention provides a method of detecting (e.g., by flow cytometry) a target compound, cell or particle, wherein the target is labelled with a detectable luminescent compound. The method comprises utilizing as the detectable luminescent compound a compound comprising a porphyrinic macrocycle such as a porphyrin, chlorin, bacteriochlorin, or isobacteriochlorin. In particular embodiments, the detectable luminescent compound comprises a compound of the formula A-A′-Z-B′—B, wherein: A is a targeting group or member of a specific binding pair that specifically binds the detectable luminescent compound to the target compound, cell or particle; A′ is a linker group or covalent bond; B′ is a linker group or covalent bond; B is a water-soluble group; and Z is the porphyrinic macrocycle.
摘要翻译： 本发明提供了检测（例如，通过流式细胞术）目标化合物，细胞或颗粒的方法，其中靶标用可检测的发光化合物标记。 所述方法包括使用包含卟啉大环化合物如卟啉，二氢卟酚，细菌二氢卟酚或异细菌素的化合物作为可检测的发光化合物。 在具体实施方案中，可检测的发光化合物包含式A-A'-Z-B'-B的化合物，其中：A是特异性结合对的靶向基团或特异性结合对的成员，其将可检测的发光化合物特异性结合到靶 化合物，细胞或颗粒; A'是连接基团或共价键; B'是连接基团或共价键; B是水溶性基团; Z是卟啉大环。
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公开(公告)号：US07501508B2
公开(公告)日：2009-03-10
申请号：US11192934
申请日：2005-07-29
IPC分类号： C07B47/00
CPC分类号： C07D403/04 , C07D487/22
摘要： A method of making a porphyrin is carried out by: (a) condensing (i) a 1,9-bis(N,N-)dialkylaminomethyl)dipyrromethane of Formula II: with (ii) a dipyrromethane to produce a reaction product; then (b) oxidizing the reaction product; and then (c) optionally demetallating said reaction product to produce the porphyrin. The reaction is particularly useful for making substituted porphyrins with a wide range of substituents at the A and/or B (the 5 and/or 15) positions.
摘要翻译： 通过以下方法进行卟啉的制备方法：（a）将（ⅰ）式Ⅱ的1,9-双（N，N-）二烷基氨基甲基）二吡咯烷与（ⅱ）二吡咯甲烷缩合生成反应产物; 然后（b）氧化反应产物; 然后（c）任选地使所述反应产物脱金属以产生卟啉。 该反应对于在A和/或B（5和/或15）位置制备具有宽范围取代基的取代卟啉是特别有用的。
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