公开(公告)号：US07856518B2

公开(公告)日：2010-12-21

申请号：US12319497

申请日：2009-01-08

申请人： Kenji Yoshida

发明人： Kenji Yoshida

IPC分类号： G06F13/12

CPC分类号： G06F3/0659 ,  G06F3/0605 ,  G06F3/0679 ,  G06F11/1446

摘要： An information processing device comprising a data record medium access unit into which a data record medium, which has a first operation mode and a second operation mode as operation modes and has a first sub-operation mode and a second sub-operation mode as sub-operation modes of the second operation mode, is inserted and which gains access to the inserted data record medium, wherein it is necessary to stop power supply to the data record medium when the access to the data record medium is switched between the first operation mode and the second operation mode, but it is not necessary to stop the power supply to the data record medium when the access to the data record medium is switched between the first sub-operation mode and the second sub-operation mode and a selection unit which allows a user to select a type of access to the data record medium inserted into the data record medium access unit, wherein the information processing device is able to select an operation mode having a fastest data transmission rate among operation modes in which a newly detected data record medium is operable on the basis of a mode selection table.

摘要翻译： 一种信息处理装置，包括：数据记录介质存取单元，具有第一操作模式和第二操作模式的数据记录介质作为操作模式并具有第一子操作模式和第二子操作模式作为子操作模式， 插入第二操作模式的操作模式，并且其访问插入的数据记录介质，其中当在第一操作模式和第一操作模式之间切换访问数据记录介质时，需要停止对数据记录介质的供电 第二操作模式，但是当在第一子操作模式和第二子操作模式之间切换对数据记录介质的访问时，不需要停止向数据记录介质的电力供应，以及允许 用户选择对插入到数据记录介质访问单元中的数据记录介质的访问的类型，其中信息处理设备能够选择具有 基于模式选择表，可以操作新检测的数据记录介质的操作模式之间的最快的数据传输速率。

公开(公告)号：US20100210661A1

公开(公告)日：2010-08-19

申请号：US12311500

申请日：2007-10-02

申请人： Kazuo Sekiguchi ,  Takashi Suzuki ,  Yutaka Ohbuchi ,  Mitsuhiro Okuno ,  Naoto Ohi ,  Kenji Ohnishi ,  Masaaki Motoyama ,  Kenji Yoshida ,  Takeshi Kodama ,  Kazuhisa Sugiyama ,  Seiji Akamatsu ,  Kunihiko Kiyono ,  Yasuo Yanagihara ,  Takashi Watanabe ,  Kazuhiko Hayashi ,  Hideo Tanaka ,  Takumi Sumida

发明人： Kazuo Sekiguchi ,  Takashi Suzuki ,  Yutaka Ohbuchi ,  Mitsuhiro Okuno ,  Naoto Ohi ,  Kenji Ohnishi ,  Masaaki Motoyama ,  Kenji Yoshida ,  Takeshi Kodama ,  Kazuhisa Sugiyama ,  Seiji Akamatsu ,  Kunihiko Kiyono ,  Yasuo Yanagihara ,  Takashi Watanabe ,  Kazuhiko Hayashi ,  Hideo Tanaka ,  Takumi Sumida

IPC分类号： A61K31/496 ,  C07D401/14 ,  C07D405/10 ,  A61P3/04 ,  A61P25/28 ,  A61P3/10

CPC分类号： C07D401/12 ,  C07D213/38 ,  C07D401/04 ,  C07D405/12 ,  C07D405/14

摘要： An object of the present invention is to provide a STAT3/5 activation inhibitor. The present invention provides a STAT3/5 activation inhibitor containing an aromatic compound represented by the general formula or a salt thereof as an active ingredient: wherein X1 represents a nitrogen atom or a group —CH═, R1 represents a group —Z—R6, in which Z represents a group —CO—, a group —CH(OH)— or the like, R6 represents a 5- to 15-membered monocyclic, dicyclic or tricyclic saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms or sulfur atoms, R2 represents a hydrogen atom or a halogen atom, Y represents a group —O—, a group —CO—, a group —CH(OH)— or a lower alkylene group, and A represents a group wherein R3 represents a hydrogen atom, a lower alkoxy group or the like, p represents 1 or 2, R4 represents an imidazolyl lower alkyl group or the like.

摘要翻译： 本发明的目的是提供一种STAT3 / 5激活抑制剂。 本发明提供含有通式所示的芳香族化合物或其盐作为活性成分的STAT3 / 5活化抑制剂，其中，X1表示氮原子或-CH =，R1表示-Z-R6基， 其中Z表示-CO-基团，-CH（OH） - 基等，R6表示具有1-4个氮原子的5至15元单环，二环或三环饱和或不饱和杂环基，氧原子 或硫原子，R 2表示氢原子或卤素原子，Y表示基团-O-，基团-CO-，基团-CH（OH） - 或低级亚烷基，A表示其中R 3表示 氢原子，低级烷氧基等，p表示1或2，R4表示咪唑基低级烷基等。

公开(公告)号：US20100209439A1

公开(公告)日：2010-08-19

申请号：US12666418

申请日：2008-06-25

申请人： Kenji Yoshida

发明人： Kenji Yoshida

IPC分类号： C07K16/30 ,  A61K39/395

CPC分类号： C07K16/2896 ,  C07K2317/24 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/72

摘要： An objective of the present invention is to provide antibodies that bind to Prominin-1 and have ADCC activity and/or CDC activity, and pharmaceutical compositions containing those antibodies as an active ingredient.To achieve a solution to the above-mentioned objective, the present inventors produced recombinant antibodies by cloning a nucleotide sequence of the AC133 antibody variable region, discovered that the ADCC/CDC-inducing effect which does not exist in the original AC133 antibody is imparted to the recombinant antibodies, and thereby completed the present invention. In the human chimeric antibody/human effector cell combination, the chimeric antibody whose constant region sequence had been converted to human IgG1/κ was found to induce strong ADCC. Furthermore, the present inventors produced humanized antibodies prepared by grafting the AC133 antibody CDRs to a human antibody sequence, and further produced humanized antibodies having binding activities equivalent to the activity of the chimeric antibody by introducing amino acid substitutions into the humanized L chain sequence. The present invention provides unlabeled AC133 human chimeric antibodies and humanized antibodies having antitumor effects.

摘要翻译： 本发明的目的是提供结合Prominin-1并具有ADCC活性和/或CDC活性的抗体，以及含有这些抗体作为活性成分的药物组合物。 为了实现上述目的的解决方案，本发明人通过克隆AC133抗体可变区的核苷酸序列产生重组抗体，发现赋予原始AC133抗体中不存在的ADCC / CDC诱导作用赋予 重组抗体，从而完成了本发明。 在人嵌合抗体/人效应细胞组合中，其恒定区序列已转化为人IgG1 / 被发现诱导强ADCC。 此外，本发明人通过将AC133抗体CDR移植到人抗体序列而制备人源化抗体，并通过将人源化L链序列引入氨基酸取代而进一步制备具有与嵌合抗体活性相当的结合活性的人源化抗体。 本发明提供了未标记的AC133人嵌合抗体和具有抗肿瘤作用的人源化抗体。

公开(公告)号：US20100121737A1

公开(公告)日：2010-05-13

申请号：US12523015

申请日：2008-01-15

申请人： Kenji Yoshida

发明人： Kenji Yoshida

IPC分类号： G06Q20/00 ,  G06K7/00 ,  G06Q30/00

CPC分类号： G07F19/205 ,  G06F3/0418 ,  G06F3/04886 ,  G06F21/31 ,  G06F21/313 ,  G06F21/34 ,  G06F21/36 ,  G06F21/83 ,  G06Q20/40 ,  G06Q30/0601 ,  G07C9/00039 ,  G07F7/10 ,  G07F7/1033 ,  G07F19/20

摘要： A PIN code input method which is low cost and operated easily and ensures high security is presented. The PIN code input method specifies and inputs a plurality of identifiable symbol icons printed or displayed on a medium surface in a predetermined order, based on which order the PIN code is authenticated. The PIN code input method uses a dot pattern signifying a coordinate value or/and a code value formed on the medium surface where the symbol icons are printed or the visual surface where the symbol icons are displayed. The dot pattern is read by a scanner and converted into the PIN code according to the coordinate value or/and code value. The PIN code is authenticated based on the order of the PIN code read. Upon reading the dot pattern by the scanner, the orientation of the scanner relative to a vertical axis perpendicular to the medium surface or the visual surface is input together with the coordinate value or/and code value signified by the dot pattern as the PIN code.

摘要翻译： 提供了低成本，易于操作并确保高安全性的PIN码输入方法。 PIN码输入法基于PIN码被认证的顺序，以预定顺序指定和输入在介质表面上打印或显示的多个可识别符号图标。 PIN码输入法使用表示在打印符号图标的介质表面上形成的坐标值或/和代码值的点图案或者显示符号图标的视觉表面。 点阵图由扫描仪读取，并根据坐标值或/和代码值转换为PIN码。 PIN码根据读取的PIN码的顺序进行认证。 在通过扫描仪读取点阵图形时，扫描仪相对于垂直于中间表面或视觉表面的垂直轴的取向与由点阵图形表示的坐标值或/和代码值一起输入作为PIN码。

公开(公告)号：US20100046110A1

公开(公告)日：2010-02-25

申请号：US12546606

申请日：2009-08-24

申请人： Kenji Yoshida

发明人： Kenji Yoshida

IPC分类号： G11B19/02

CPC分类号： G11B19/02

摘要： Disclosed is an information processing apparatus. The information processing apparatus includes a first hard disk drive, a conversion circuit and a signal control circuit. The conversion circuit is connected with the first hard disk drive to determine whether a second hard disk drive corresponding to a slave exists when the first hard disk drive serves as a master, and the determine whether a first control signal has a first logic level in a first predetermined time.

摘要翻译： 公开了一种信息处理装置。 信息处理装置包括第一硬盘驱动器，转换电路和信号控制电路。 转换电路与第一硬盘驱动器连接，以确定当第一硬盘驱动器用作主机时是否存在对应于从设备的第二硬盘驱动器，并且确定第一控制信号是否具有第一逻辑电平 第一预定时间。

公开(公告)号：US07667332B2

公开(公告)日：2010-02-23

申请号：US11265231

申请日：2005-11-03

申请人： Masaaki Hatano ,  Motoya Okazaki ,  Junichi Wada ,  Takeshi Nishioka ,  Hisashi Kaneko ,  Takeshi Fujimaki ,  Kazuyuki Higashi ,  Kenji Yoshida ,  Noriaki Matsunaga

发明人： Masaaki Hatano ,  Motoya Okazaki ,  Junichi Wada ,  Takeshi Nishioka ,  Hisashi Kaneko ,  Takeshi Fujimaki ,  Kazuyuki Higashi ,  Kenji Yoshida ,  Noriaki Matsunaga

IPC分类号： H01L23/52 ,  H01L23/48 ,  H01L29/40

CPC分类号： G06F17/5068

摘要： A method for generating a pattern includes reading out an interconnect layout and a hole layout, the interconnect layout prescribing interconnect patterns, the hole layout prescribing hole patterns configured to connect to the interconnect patterns; extracting one of the hole patterns to be connected within the same interconnect layer level to one of the interconnect patterns in a pattern processing area; extracting a first processing area including the extracted hole pattern; calculating a first pattern density of the interconnect patterns included in the first processing area; and generating first additional patterns in the first processing area based on the first pattern density.

摘要翻译： 一种用于产生图案的方法包括：读出互连布局和孔布局;布置规定互连图案的布局布局;布置配置为连接到互连图案的孔图案的孔布局; 在图案处理区域中将在相同互连层级中连接的孔图案中的一个提取到所述互连图案之一; 提取包括所提取的孔图案的第一处理区域; 计算包括在第一处理区域中的互连图案的第一图案密度; 以及基于所述第一图案密度在所述第一处理区域中生成第一附加图案。

公开(公告)号：US20100039053A1

公开(公告)日：2010-02-18

申请号：US12605373

申请日：2009-10-26

申请人： Ryuta MATSUTANI ,  Kenji Yoshida ,  Shigeru Sakurai

发明人： Ryuta MATSUTANI ,  Kenji Yoshida ,  Shigeru Sakurai

IPC分类号： H02P5/46

CPC分类号： B25B21/00 ,  B23P19/066 ,  B25B23/14

摘要： A torque control device controlling torque of first and second mechanical units connected coaxially to each other through connecting members includes a controller generating first and second references from a command from a host system, first and second motors respectively driving the first and second mechanical units, first and second motor control units respectively controlling the first and second motors on the basis of the first and second references. The first and second references synchronously accelerate the first and second motors to first rotational speed, then increase rotational speed of the second motor according to a speed profile to produce torsional torque in the connecting members, decelerate the second motor to the first rotational speed after the torsional torque reaches a predetermined value, and synchronously decelerate and stop the first and second motors after a predetermined time period elapses.

摘要翻译： 控制通过连接构件彼此同轴连接的第一和第二机械单元的扭矩的转矩控制装置包括控制器，其根据来自主机系统的命令产生第一和第二参考，第一和第二电动机分别驱动第一和第二机械单元，第一 以及第二电动机控制单元，其基于第一和第二参考分别控制第一和第二电动机。 第一和第二参考同步地将第一和第二电动机加速到第一转速，然后根据速度曲线提高第二电动机的转速，以在连接构件中产生扭转扭矩，在第二电动机之后将第二电动机减速到第一转速 扭转扭矩达到预定值，并且在经过预定时间段之后同步地减速和停止第一和第二电动机。

公开(公告)号：US20090276685A1

公开(公告)日：2009-11-05

申请号：US12345578

申请日：2008-12-29

申请人： Kenji Yoshida

发明人： Kenji Yoshida

IPC分类号： H03M13/05 ,  G06F11/07

CPC分类号： G11B20/1833 ,  G11B2020/185 ,  G11B2220/2516

摘要： A data decoding apparatus has: a check matrix including a submatrix which indicates a parity restriction and used for LDPC decoding; a first decoding module configured to decode data by using the submatrix so that the parity restriction is satisfied; and a second decoding module configured to LDPC-decode the decoded data by using the check matrix.

摘要翻译： 数据解码装置具有：包括表示奇偶限制并用于LDPC解码的子矩阵的校验矩阵; 第一解码模块，被配置为通过使用所述子矩阵来解码数据，使得满足所述奇偶限制; 以及第二解码模块，被配置为通过使用所述校验矩阵对所解码的数据进行LDPC解码。

公开(公告)号：US07573659B2

公开(公告)日：2009-08-11

申请号：US11925373

申请日：2007-10-26

申请人： Ichiro Onuki ,  Kenichi Kobayashi ,  Kenji Yoshida ,  Jun Ota

发明人： Ichiro Onuki ,  Kenichi Kobayashi ,  Kenji Yoshida ,  Jun Ota

IPC分类号： G02B7/02

CPC分类号： G02B27/62 ,  G02B7/023 ,  G03F7/70825 ,  G03F7/7085

摘要： A holding apparatus for holding an optical element includes a measuring part configured to measure a coordinate of the optical element, and a driving part configured to move the optical element based on the coordinate measured by the measuring part, wherein the measuring part includes a first sensor configured to detect a displacement amount of a part of the optical element, and a second sensor configured to detect that a part of the optical element is located at a predetermined position.

摘要翻译： 用于保持光学元件的保持装置包括被配置为测量光学元件的坐标的测量部件和被配置为基于由测量部件测量的坐标来移动光学元件的驱动部件，其中测量部件包括第一传感器 被配置为检测所述光学元件的一部分的位移量;以及第二传感器，被配置为检测所述光学元件的一部分位于预定位置。

公开(公告)号：US20090153999A1

公开(公告)日：2009-06-18

申请号：US12165459

申请日：2008-06-30

申请人： Kenji Yoshida ,  Yuuichi Abe

发明人： Kenji Yoshida ,  Yuuichi Abe

IPC分类号： G11B15/18 ,  G11B5/82 ,  G11B27/00

CPC分类号： G11B20/1883 ,  G11B2020/1281 ,  G11B2020/1893 ,  G11B2220/20 ,  G11B2220/2516

摘要： A hard disk includes: a plurality of servo areas which are elongated radially from a center of the hard disk to an outward thereof over tracks thereof; and a plurality of data areas which are respectively provided between the plurality of servo areas; wherein alternative operation is conducted per servo sector containing one of the plurality of servo areas and a data area provided subsequent to the one of the plurality of servo areas and having a defect created therein when a user sector containing at least a portion of the data area and functioning as an access unit has the defect therein.

摘要翻译： 硬盘包括：多个伺服区，其从硬盘的中心径向延伸到其轨道的外侧; 以及分别设置在所述多个伺服区域之间的多个数据区域; 其中，对于包含所述多个伺服区域中的一个的每个伺服扇区和在所述多个伺服区域中的所述伺服区域之后提供的数据区域进行替换操作，并且当包含所述数据区域的至少一部分的用户扇区 并且作为存取单元起作用。