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公开(公告)号:US20110049357A1
公开(公告)日:2011-03-03
申请号:US12679139
申请日:2008-09-22
申请人: Kevin Giles
发明人: Kevin Giles
IPC分类号: H01J49/00
CPC分类号: H01J49/065 , H01J49/062 , H01J49/26
摘要: An ion guiding device is disclosed comprising a first ion guide (7) which is conjoined with a second ion guide (8). Ions are urged across a radial pseudo-potential barrier which separates the two guiding regions by a DC potential gradient. Ions may be transferred from an ion guide which has a relatively large cross-sectional profile to an ion guide which has a relatively small cross-sectional profile in order to improve the subsequent ion confinement of the ions.
摘要翻译: 公开了一种离子引导装置,其包括与第二离子引导件(8)结合的第一离子引导件(7)。 离子通过将两个引导区域分离直流电势梯度的径向伪电势势垒。 离子可以从具有相对较大截面轮廓的离子导向器转移到具有相对较小横截面轮廓的离子导向器,以改进离子的后续离子限制。
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公开(公告)号:US20110042563A1
公开(公告)日:2011-02-24
申请号:US12917755
申请日:2010-11-02
申请人: Kevin Giles
发明人: Kevin Giles
IPC分类号: B01D59/44
CPC分类号: H01J49/065 , G01N27/624
摘要: A device 6 for separating ions according to differences in their ion mobility as a function of electric field strength is disclosed. The device 6 comprises an upper electrode 7a, a lower electrode 7b and a plurality of intermediate electrodes 8. An asymmetric voltage waveform is applied to the upper electrode 7a and a DC compensating voltage is applied to the lower electrode 7b.
摘要翻译: 公开了根据其离子迁移率的差异作为电场强度的函数分离离子的装置6。 器件6包括上电极7a,下电极7b和多个中间电极8.对上电极7a施加非对称电压波形,并向下电极7b施加直流补偿电压。
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公开(公告)号:US20100044561A1
公开(公告)日:2010-02-25
申请号:US12373341
申请日:2007-07-12
申请人: Kevin Giles
发明人: Kevin Giles
IPC分类号: H01J49/26
CPC分类号: H01J49/0481 , G01N27/622 , H01J49/004 , H01J49/062
摘要: A mass spectrometer is disclosed comprising a first chamber (10) and a second chamber (5). The second chamber (5) is located downstream of the first chamber 10 and an inter-chamber aperture (12) is provided between the two chambers (5,10). An ion guide (13) is located in the first chamber (10) and an ion mobility spectrometer (6) is located in the second chamber (5). Helium gas is provided to the first chamber (10). As ions are accelerated towards the ion mobility spectrometer 6 from a relatively low pressure region they pass initially into the first chamber (10). The helium gas provided in the first chamber (10) minimises ion fragmentation and ion discrimination effects as ions are accelerated into a relatively high pressure region. The ions are then transmitted by the ion guide (13) and are subsequently transmitted to the ion mobility spectrometer (6) located in the second chamber (5).
摘要翻译: 公开了一种质谱仪,其包括第一室(10)和第二室(5)。 第二室(5)位于第一室10的下游,并且在两个室(5,10)之间设置室间孔(12)。 离子导向器(13)位于第一室(10)中,离子迁移谱仪(6)位于第二室(5)中。 氦气被提供到第一室(10)。 当离子从相对低的压力区域向离子迁移谱仪6加速时,它们首先进入第一腔室(10)。 设置在第一室(10)中的氦气最小化离子碎片和离子鉴别效应,因为离子被加速到相对高的压力区域。 然后离子由离子引导件(13)传输,随后被传递到位于第二室(5)中的离子迁移谱仪(6)。
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公开(公告)号:US20090194688A1
公开(公告)日:2009-08-06
申请号:US11719665
申请日:2005-11-18
CPC分类号: H01J49/4215 , H01J49/428
摘要: A mass spectrometer is disclosed comprising a quadrupole rod set ion guide or mass filter device (6). A broadband frequency signal (10) having one or more notches (11a, 11b, 11c) is applied to the rods of the quadrupole rod set (6). The notched broadband frequency signal (10) causes undesired ions to be resonantly ejected from the ion guide (6). The notched broadband frequency signal (10) has frequency components missing which correspond with the resonance frequency of ions which are desired to be onwardly transmitted. The ion guide or mass filter device (6) enables a plurality of desired ions having different mass to charge ratios to be simultaneously transmitted by the ion guide or mass filter device (6) whilst other ions are resonantly ejected from the ion guide or mass filter device (6).
摘要翻译: 公开了一种质谱仪,其包括四极杆离子导向器或质量过滤装置(6)。 具有一个或多个凹口(11a,11b,11c)的宽频率信号(10)被施加到四极杆组(6)的杆上。 有缺口的宽带频率信号(10)使不想要的离子从离子导向器(6)共振地弹出。 缺口宽带频率信号(10)具有与期望向前发射的离子的谐振频率相对应的频率分量。 离子导向器或质量过滤装置(6)使得具有不同质荷比的多个所需离子能够由离子导向器或质量过滤装置(6)同时传输,而其它离子从离子导向器或质量过滤器 装置(6)。
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公开(公告)号:US20090173877A1
公开(公告)日:2009-07-09
申请号:US12092601
申请日:2005-11-10
CPC分类号: H01J49/004 , G01N27/622 , H01J49/0031 , H01J49/42
摘要: A mass spectrometer is disclosed comprising a first ion trap or ion guide (2), a single ion mobility spectrometer or separator stage (3) and a second ion trap or ion guide (4) arranged downstream of the ion mobility spectrometer or separator (3). In a mode of operation ions from the second ion trap or ion guide (4) are passed from the second ion trap or ion guide back upstream to the ion mobility spectrometer or separator (3).
摘要翻译: 公开了一种质谱仪,其包括第一离子阱或离子导向器(2),单离子迁移谱仪或分离器级(3)和设置在离子迁移谱仪或分离器(3)的下游的第二离子阱或离子导向器 )。 在操作模式中,来自第二离子阱或离子导向器(4)的离子从第二离子阱或离子导向器返回到离子迁移谱仪或分离器(3)的上游。
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公开(公告)号:US06838662B2
公开(公告)日:2005-01-04
申请号:US10693874
申请日:2003-10-28
CPC分类号: H01J49/4235
摘要: A mass spectrometer is disclosed comprising a mass filter for separating ions according to their mass to charge ratio. The mass filter comprises a plurality of electrodes wherein ions are radially confined within the mass filter by the application of AC or RF voltages to the electrodes. One or more transient DC voltages or one or more transient DC voltage waveforms are progressively applied to the electrodes so that ions having a certain mass to charge ratio are separated from other ions having different mass to charge ratios which remain radially confined within the mass filter.
摘要翻译: 公开了一种质谱仪,其包括用于根据其质荷比分离离子的质量过滤器。 质量过滤器包括多个电极,其中通过向电极施加AC或RF电压,离子径向地限制在质量过滤器内。 一个或多个瞬态直流电压或一个或多个瞬态直流电压波形逐渐地施加到电极,使得具有一定质荷比的离子与具有不同质量与电荷比的其它离子分离,这些离子保持径向地限制在质量过滤器内。
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公开(公告)号:US06762404B2
公开(公告)日:2004-07-13
申请号:US10178347
申请日:2002-06-25
IPC分类号: H01J4900
CPC分类号: H01J49/005 , H01J49/065
摘要: A mass spectrometer includes a fragmentation cell having a plurality of ring or plate-like electrodes with apertures through which ions are transmitted. An axial DC gradient is preferably maintained along at least a portion of the length of the fragmentation cell in order to improve the transit time of ions through the device.
摘要翻译: 质谱仪包括具有多个具有孔的环状或板状电极的分裂单元,离子被透过。 轴向DC梯度优选沿破碎细胞的长度的至少一部分保持,以便改善离子通过装置的通过时间。
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