公开(公告)号：US06987615B2

公开(公告)日：2006-01-17

申请号：US10264467

申请日：2002-10-04

申请人： Teruhiro Shiono ,  Hidenori Wada ,  Seiji Nishino

发明人： Teruhiro Shiono ,  Hidenori Wada ,  Seiji Nishino

IPC分类号： G02B5/18

CPC分类号： G11B7/1275 ,  G02B5/1871 ,  G11B2007/0006

摘要： A diffractive optical element emits substantially zero order diffracted light when light with a wavelength of 0.35 μm to 0.45 μm is incident and emits substantially first-order diffracted light when light with a wavelength of 0.6 μm to 0.7 μm is incident. The diffractive optical element includes a substrate and a grating portion formed on the substrate. The grating portion has a step-wise cross section with any one of levels selected from four levels, five levels and six levels. The diffractive optical element emits substantially zero-order diffracted light when light with a first wavelength λ1 satisfying the relationship: 0.35 μm≦λ1≦0.45 μm is incident and emits substantially first-order diffracted light when light with a second wavelength λ2 satisfying the relationship: 0.6 μm≦λ2≦0.7 μm is incident.

摘要翻译： 当波长为0.35μm至0.45μm的光入射时，衍射光学元件发射基本为零级的衍射光，并且当入射具有0.6μm至0.7μm波长的光时，发射基本上为一级的衍射光。 衍射光学元件包括基板和形成在基板上的光栅部分。 光栅部分具有从四个级别，五个级别和六个级别中选择的任何一个级别的逐步横截面。 当具有第一波长λ1的满足0.35μm<λλ=0.45μm的关系的光入射时，衍射光学元件发射基本上为零级的衍射光，并且当具有第二波长λ的光时发射基本上一级的衍射光 2满足关系：0.6mum <=λ2 <=0.7μm是入射的。

公开(公告)号：US20050157629A1

公开(公告)日：2005-07-21

申请号：US10510400

申请日：2003-04-07

申请人： Teruhiro Shiono ,  Hiroaki Yamamoto ,  Seiji Nishino ,  Tsuneo Mitsuyu

发明人： Teruhiro Shiono ,  Hiroaki Yamamoto ,  Seiji Nishino ,  Tsuneo Mitsuyu

IPC分类号： G11B7/0045 ,  G11B7/24038 ,  G11B7/242 ,  G11B7/243 ,  G11B7/245 ,  G11B7/2533 ,  G11B7/2534 ,  G11B7/2538 ,  G11B7/2542 ,  G11B7/257 ,  G11B7/258 ,  G11B7/26 ,  G11B7/24

CPC分类号： G11B7/243 ,  B82Y10/00 ,  B82Y30/00 ,  G11B7/00455 ,  G11B7/24038 ,  G11B7/251 ,  G11B7/2533 ,  G11B7/2534 ,  G11B7/2538 ,  G11B7/2542 ,  G11B7/257 ,  G11B7/258 ,  G11B7/266 ,  G11B2007/24304 ,  G11B2007/24306 ,  G11B2007/2431 ,  G11B2007/24312 ,  G11B2007/2432 ,  G11B2007/24324

摘要： An information recording medium has a recording portion where three-dimensional information can be recorded. The recording portion includes at least one particle-containing layer (recording layer or a recording auxiliary layer) containing particles absorbing at least a part of light having a predetermined wavelength and substantially transparent to a recording light and a reproducing light having a wavelength longer than the predetermined wavelength and a particle holding material substantially transparent to the recording and reproducing lights. The mean particle size of the particles is preferably shorter than the wavelengths of the recording and reproducing lights.

摘要翻译： 信息记录介质具有记录三维信息的记录部分。 记录部分包括至少一个含有颗粒的层（记录层或记录辅助层），其含有吸收具有预定波长的至少一部分光并且对记录光基本透明的颗粒和具有比该 预定波长和对记录和再现光基本上透明的颗粒保持材料。 颗粒的平均粒度优选比记录和再现光的波长短。

公开(公告)号：US20050048538A1

公开(公告)日：2005-03-03

申请号：US10868379

申请日：2004-06-14

申请人： Emmanuel Mignot ,  Juliette Faraco ,  Hua Li ,  Ling Lin ,  Seiji Nishino ,  Hiroshi Kadatoni

发明人： Emmanuel Mignot ,  Juliette Faraco ,  Hua Li ,  Ling Lin ,  Seiji Nishino ,  Hiroshi Kadatoni

IPC分类号： A61K38/17 ,  C07K14/705 ,  C12Q1/68

CPC分类号： C12Q1/6883 ,  A61K38/22 ,  C07K14/70571 ,  C12Q2600/156

摘要： The present invention is directed to methods for identification of compounds that affect wakefulness, attention deficit hyperactivity disorder, chronic fatigue syndrome and mood disorders (e.g., depression) through interaction with the hypocretin receptor system. The present invention is also directed to detection of abnormal levels of hypocretin in a subject, as well as detection of an abnormal immune response against hypocretin (orexins) and/or their receptors, where detection of abnormal hypocretin levels or detection of an abnormal immune response is indicative of a sleep disorder, particularly of narcolepsy. The present invention is also directed to a methods relating to the detection of a mutation or polymorphism in the gene encoding the hypocretin receptors, the detection of antibodies disrupting the function of gene encoding hypocretin receptors and hypocretin polypeptides, and the use of hypocretin biological markers in predicting treatment response using compounds interacting with the hypocretin receptor system.

摘要翻译： 本发明涉及通过与神经突触素受体系相互作用来鉴定影响觉醒，注意缺陷多动障碍，慢性疲劳综合征和情绪障碍（例如抑郁症）的化合物的方法。 本发明还涉及检测受试者中hypocretin的异常水平，以及检测针对hypocretin（orexins）和/或其受体的异常免疫应答，其中检测异常下丘脑水平或检测异常免疫应答 指示睡眠障碍，特别是发作性睡病。 本发明还涉及与编码下丘脑受体的基因的突变或多态性的检测有关的方法，破坏编码下丘脑神经肽受体和下丘脑多肽的基因功能的抗体的检测，以及使用下丘脑生物学标记物 使用与下丘脑受体系统相互作用的化合物预测治疗反应。

公开(公告)号：US5367403A

公开(公告)日：1994-11-22

申请号：US43228

申请日：1993-04-06

申请人： Hiroaki Yamamoto ,  Seiji Nishino ,  Kazuhisa Yamamoto

发明人： Hiroaki Yamamoto ,  Seiji Nishino ,  Kazuhisa Yamamoto

IPC分类号： G02B5/18 ,  G02B5/30 ,  G02B27/28 ,  G11B7/135 ,  G11B11/105

CPC分类号： G11B7/1353 ,  G02B27/283 ,  G02B5/1833 ,  G02B5/3083 ,  G11B11/10515 ,  G11B11/10545

摘要： An optical element includes a crystal of LiTa.sub.X Nb.sub.1-X O.sub.3 which has one of an x-surface and a y-surface, where X denotes an atomic fraction and 0.ltoreq.X.ltoreq.1. Proton-exchanged layers periodically extend on one of the x-surface and the y-surface of the crystal. Grooves extend in said one of the x-surface and the y-surface of the crystal, and have bottoms which are defined by surfaces of the proton-exchanged layers. Ordinary light which has passed through the proton-exchanged layers and the grooves is out of phase with respect to ordinary light which has passed through a region of the crystal outside the proton-exchanged layers and the grooves by a quantity of (2n+1).pi., where n denotes an arbitrary integer. Extraordinary light which has passed through the proton-exchanged layers and the grooves is out of phase with respect to extraordinary light which has passed through a region of the crystal outside the proton-exchanged layers and the grooves by a quantity of 2 m.pi., where m denotes an arbitrary integer.

摘要翻译： 光学元件包括具有x表面和y表面之一的LiTaXNb1-XO3的晶体，其中X表示原子分数，0表示X <= 1。 质子交换层周期性延伸在晶体的x面和y表面之一上。 沟槽在晶体的x表面和y表面中的所述一个中延伸，并且具有由质子交换层的表面限定的底部。 通过质子交换层和槽的普通光相对于通过质子交换层外侧的晶体区域和沟槽的一定数量的（2n + 1）的普通光而异相， pi，其中n表示任意整数。 已经通过质子交换层和沟槽的非凡光相对于通过质子交换层外面的晶体区域和沟槽的一个2μmp的非常光而异相，其中 m表示任意整数。

公开(公告)号：US07394733B2

公开(公告)日：2008-07-01

申请号：US11451779

申请日：2006-06-13

申请人： Teruhiro Shiono ,  Keiichi Matsuzaki ,  Hidenori Wada ,  Seiji Nishino

发明人： Teruhiro Shiono ,  Keiichi Matsuzaki ,  Hidenori Wada ,  Seiji Nishino

IPC分类号： G11B7/00

CPC分类号： G11B7/13925 ,  G11B7/1353 ,  G11B7/1367 ,  G11B7/1369 ,  G11B7/13922

摘要： An optical head with excellent optical characteristics even when using a light source that substantially has a wavelength broadening is provided. The optical head includes a light source, an objective lens for focusing a light beam emitted from the light source on an information recording medium and a photodetector for detecting the light beam reflected from the information recording medium, wherein defocusing correction means and spherical aberration correction means are provided in an optical path between the light source and the information recording medium. Since both the defocusing correction means and the spherical aberration correction means are provided, while defocusing of a focused spot on the information recording medium caused by a wavelength broadening of the light source and chromatic aberration of the optical system can be corrected, the spherical aberration of the optical system caused by wavelength difference between a design wavelength and an incident wavelength also can be corrected. As a result, excellent optical characteristics can be obtained.

摘要翻译： 提供即使在使用基本上具有波长变宽的光源的情况下也具有优异的光学特性的光学头。 光头包括光源，用于将从光源发射的光束聚焦在信息记录介质上的物镜和用于检测从信息记录介质反射的光束的光电检测器，其中散焦校正装置和球面像差校正装置 设置在光源和信息记录介质之间的光路中。 由于提供了散焦校正装置和球面像差校正装置两者，所以可以校正由光源的波长变宽和光学系统的色差引起的信息记录介质上的聚焦点的散焦， 也可以校正由设计波长和入射波长之间的波长差引起的光学系统。 结果，可以获得优异的光学特性。

公开(公告)号：US20060120256A1

公开(公告)日：2006-06-08

申请号：US10539666

申请日：2004-02-25

申请人： Seiji Nishino ,  Teruhiro Shiono ,  Hiroaki Yamamoto ,  Tatsuo Ito

发明人： Seiji Nishino ,  Teruhiro Shiono ,  Hiroaki Yamamoto ,  Tatsuo Ito

IPC分类号： G11B7/24

CPC分类号： B82Y10/00 ,  G11B7/2403 ,  G11B7/24038 ,  G11B7/24067

摘要： An optical information recording carrier comprising a substrate and at least one recording film arranged on the substrate is disclosed. Information is recorded on the recording film through irradiation with a recording light having a predetermined wavelength (λ). The recording film is composed of a heat generating layer and at least one dielectric layer arranged in contact with the heat generating layer. The heat generating layer and the dielectric layer are substantially transparent to the recording light with wavelength (λ), and are respectively formed to have a predetermined thickness and a predetermined refractive index so that the field intensity of the recording light becomes maximum at the interface between the heat generating layer and the dielectric layer.

摘要翻译： 公开了一种包括基板和布置在基板上的至少一个记录膜的光学信息记录载体。 信息通过用具有预定波长（λ）的记录光照射而记录在记录膜上。 记录膜由发热层和布置成与发热层接触的至少一个电介质层组成。 发热层和电介质层对具有波长（λ）的记录光基本上是透明的，分别形成为具有预定厚度和预定折射率，使得记录光的场强在第 发热层和电介质层。

公开(公告)号：US20060072438A1

公开(公告)日：2006-04-06

申请号：US10527018

申请日：2003-09-02

申请人： Seiji Nishino ,  Teruhiro Shiono ,  Hiroaki Yamamoto

发明人： Seiji Nishino ,  Teruhiro Shiono ,  Hiroaki Yamamoto

IPC分类号： G11B7/24

CPC分类号： G11B7/24038 ,  B82Y10/00 ,  G11B7/245 ,  G11B7/2475 ,  G11B7/252 ,  G11B7/2534 ,  G11B7/2542 ,  G11B7/2575 ,  G11B2007/0013 ,  G11B2007/24304 ,  G11B2007/2432 ,  G11B2007/24324

摘要： To provide an optical information storage medium with high recording/reproducing sensitivity. An optical information storage medium 100 includes a substrate 56 and a multilayer structure 49, which is provided on the substrate 56 and includes at least one storage layer 57. The storage layer 57 includes polydiacetylene or merocyanine and is amorphous.

摘要翻译： 提供具有高记录/再现灵敏度的光学信息存储介质。 光学信息存储介质100包括基板56和多层结构49，其设置在基板56上并且包括至少一个存储层57.存储层57包括聚二乙炔或部花青并且是无定形的。

公开(公告)号：US20050152036A1

公开(公告)日：2005-07-14

申请号：US11049232

申请日：2005-02-01

申请人： Teruhiro Shiono ,  Hidenori Wada ,  Seiji Nishino

发明人： Teruhiro Shiono ,  Hidenori Wada ,  Seiji Nishino

IPC分类号： G02B5/18 ,  G11B7/00 ,  G11B7/125 ,  G11B7/135

CPC分类号： G11B7/1275 ,  G02B5/1871 ,  G11B2007/0006

摘要： A diffractive optical element emits substantially zero order diffracted light when light with a wavelength of 0.35 μm to 0.45 μm is incident and emits substantially first-order diffracted light when light with a wavelength of 0.6 μm to 0.7 μm is incident. The diffractive optical element includes a substrate and a grating portion formed on the substrate. The grating portion has a step-wise cross section with any one of levels selected from four levels, five levels and six levels. The diffractive optical element emits substantially zero-order diffracted light when light with a first wavelength λ1 satisfying the relationship: 0.35 μm≦λ1≦0.45 μm is incident and emits substantially first-order diffracted light when light with a second wavelength λ2 satisfying the relationship: 0.6 μm≦λ2≦0.7 μm is incident.

摘要翻译： 当波长为0.35μm至0.45μm的光入射时，衍射光学元件发射基本为零级的衍射光，并且当入射具有0.6μm至0.7μm波长的光时，发射基本上为一级的衍射光。 衍射光学元件包括基板和形成在基板上的光栅部分。 光栅部分具有从四个级别，五个级别和六个级别中选择的任何一个级别的逐步横截面。 当具有满足以下关系的第一波长λ1的光时，衍射光学元件发射基本为零级的衍射光，即当第二波长λ2的光满足以下条件时，基本上为一级衍射光 关系：0.6 mum <= lambda2 <= 0.7 mum是事件。

公开(公告)号：US06584059B1

公开(公告)日：2003-06-24

申请号：US09501380

申请日：2000-02-09

申请人： Tetsuo Saimi ,  Seiji Nishino ,  Hidenori Wada ,  Teruhiro Shiono ,  Keiichi Matsuzaki

发明人： Tetsuo Saimi ,  Seiji Nishino ,  Hidenori Wada ,  Teruhiro Shiono ,  Keiichi Matsuzaki

IPC分类号： G11B700

CPC分类号： G11B7/1353 ,  G11B7/0903 ,  G11B7/131 ,  G11B7/1369 ,  G11B7/14 ,  G11B2007/0006

摘要： An information recording and reproducing apparatus in accordance with the present invention has a radiation light source, a collimator turning a light beam emitted from the radiation light source into substantially parallel light, a light beam convergence member focusing the light beam on an information carrier, a light beam polarization-branching member branching the light beam by polarization, a variable wave plate located between the collimator and the light beam convergence member, photo detectors receiving the light beam branched by the light beam polarization-branching member and outputting a current according to an incident light quantity, and an output level judging member judging whether an output of the photo detectors is larger or smaller than a predetermined value. When the photo detectors receive a small light quantity because the information carrier is highly birefringent, the variable wave plate is switched from a ¼ wavelength plate to a zero-wave plate, thus constantly obtaining a stable reproducing signal with an excellent S/N.

摘要翻译： 根据本发明的信息记录和再现装置具有辐射光源，将从辐射光源发射的光束转换成基本平行的光的准直仪，将光束聚焦在信息载体上的光束会聚部件， 光束偏振分支部件通过偏振分支光束，位于准直器和光束会聚部件之间的可变波片，接收由光束偏振分支部件分支的光束的光检测器，并根据 以及判断光电检测器的输出是否大于或小于预定值的输出电平判断部件。 由于信息载体高度双折射，当光电检测器接收到小的光量时，可变波片从1/4波片切换到零波片，从而不断获得具有优异S / N的稳定再现信号。

公开(公告)号：US5627812A

公开(公告)日：1997-05-06

申请号：US337369

申请日：1994-11-08

申请人： Hiroaki Yamamoto ,  Seiji Nishino

发明人： Hiroaki Yamamoto ,  Seiji Nishino

IPC分类号： G02B5/18 ,  G11B7/09 ,  G11B7/13 ,  G11B7/135 ,  G11B11/10 ,  G11B11/105 ,  G02B6/12

CPC分类号： G11B7/131 ,  G02B27/4238 ,  G02B27/4261 ,  G02B27/4272 ,  G02B5/1814 ,  G11B11/10543 ,  G11B11/10576 ,  G11B7/1353 ,  G11B7/0901 ,  G11B7/0909 ,  G11B7/0912 ,  G11B7/0916

摘要： The light reading the information of an optomagnetic disk is focused by a detector lens 104, and is put into a polarizing hologram 121 and a polarizing hologram 122 composed of lithium niobate. These polarizing holograms have action to separate a polarized light component in the z-axis direction and a polarized light component orthogonal thereto into transmitted light and diffracted light. The polarizing and separating hologram 121 is installed so that its z-axis may have an inclination of 45 degrees to the principal direction of polarization of incident light, and the z-axis of the polarizing and separating hologram 122 is set in a direction orthogonal thereto. Therefore the individual polarizing holograms transform different polarized light components into different wave planes. Accordingly, in a photo detector 196, TE signal and TM signal are obtained in different polarized light components, so that the imbalance of the head amplifiers can be eliminated.

摘要翻译： 读取光磁盘的信息的光由检测器透镜104聚焦，并被放入偏光全息图121和由铌酸锂构成的偏光全息图122中。 这些偏振全息图具有将z轴方向的偏振光分量和与其正交的偏振光分量分离为透射光和衍射光的动作。 偏振和分离全息图121被安装成使得其z轴可以具有与入射光的主要偏振方向成45度的倾斜度，并且偏振和分离全息图122的z轴被设置在与其正交的方向上 。 因此，各个偏振全息图将不同的偏振光分量转换成不同的波面。 因此，在光检测器196中，以不同的偏振光分量获得TE信号和TM信号，从而可以消除头放大器的不平衡。