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公开(公告)号：US09982310B2
公开(公告)日：2018-05-29
申请号：US15243488
申请日：2016-08-22
Inventor： David A. Ahlquist , John B. Kisiel , William R. Taylor , Tracy C. Yab , Douglas W. Mahoney
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/154
Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.
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公开(公告)号：US20180037958A1
公开(公告)日：2018-02-08
申请号：US15550703
申请日：2016-03-23
Inventor： David A. Ahlquist , William R. Taylor , John B. Kisiel , Douglas W. Mahoney , Tracy C. Yab , Graham P. Lidgard , Hatim T. Allawi
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q1/6883 , C12Q2600/112 , C12Q2600/154 , C12Q2600/166 , G01N33/57407 , G01N2440/12 , G01N2800/14
Abstract: Provided herein is technology for esophageal disorder screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of esophageal disorders (e.g., Barrett's esophagus, Barrett's esophageal dysplasia, etc.). In addition, the technology provides methods, compositions and related uses for distinguishing between Barrett's esophagus and Barrett's esophageal dysplasia, and between Barrett's esophageal low-grade dysplasia, Barrett's esophageal high-grade dysplasia, and esophageal adenocarcinoma within samples obtained through endoscopic brushing or nonendoscopic whole esophageal brushing or swabbing using a tethered device (e.g. such as a capsule sponge, balloon, or other device).
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公开(公告)号：US20170198361A1
公开(公告)日：2017-07-13
申请号：US15467739
申请日：2017-03-23
Inventor： William R. Taylor , Jonathan J. Harrington , Patrick S. Quint , Hongzhi Zou , Harold S. Bergen, III , David I. Smith , David A. Ahlquist
IPC: C12Q1/68 , G01N33/574
CPC classification number: C12Q1/6886 , C12Q1/37 , C12Q1/40 , C12Q2600/154 , C12Q2600/156 , C12Q2600/158 , C12Y302/01001 , C12Y304/2107 , G01N33/57407 , G01N33/57419 , G01N33/57438 , G01N2333/928 , G01N2333/966 , G01N2560/00
Abstract: This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided.
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公开(公告)号：US20170058356A1
公开(公告)日：2017-03-02
申请号：US15252966
申请日：2016-08-31
Inventor： David A. Ahlquist , William R. Taylor , John B. Kisiel , Tracy C. Yab , Douglas W. Mahoney , Hatim T. Allawi
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/154 , C12Q2600/16
Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as gastric cancer.
Abstract translation: 本文提供了涉及检测瘤形成的技术，特别是但不排他地涉及用于检测癌前期恶变和恶性肿瘤的方法，组合物和相关用途。
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公开(公告)号：US20160355892A1
公开(公告)日：2016-12-08
申请号：US15243488
申请日：2016-08-22
Inventor： David A. Ahlquist , John B. Kisiel , William R. Taylor , Tracy C. Yab , Douglas W. Mahoney
IPC: C12Q1/68
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/154
Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.
Abstract translation: 本文提供了涉及检测瘤形成的技术，特别但并非排他地涉及用于检测恶变和恶性肿瘤如胰腺癌和结肠直肠癌的方法，组合物和相关用途。
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Patent Agency Ranking
公开(公告)号：US20250137067A1
公开(公告)日：2025-05-01
申请号：US18943079
申请日：2024-11-11
Inventor： David A. Ahlquist , William R. Taylor , John B. Kisiel , Tracy C. Yab , Douglas W. Mahoney
IPC: C12Q1/6886
Abstract: Provided herein is technology for pancreatic high-grade dysplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of pancreatic high-grade dysplasia (IPMN-HGD, PanIN-3, or PDAC).
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公开(公告)号：US20240417807A1
公开(公告)日：2024-12-19
申请号：US18746198
申请日：2024-06-18
Inventor： William R. Taylor , Jonathan J. Harrington , Patrick S. Quint , Hongzhi Zou , Harold R. Bergen, III , David I. Smith , David A. Ahlquist
IPC: C12Q1/6886 , C12Q1/37 , C12Q1/40 , G01N33/574
Abstract: This document relates to methods and materials for detecting premalignant and malignant neoplasms. For example, methods and materials for determining whether or not a stool sample from a mammal contains nucleic acid markers or polypeptide markers of a neoplasm are provided.
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公开(公告)号：US20240182976A1
公开(公告)日：2024-06-06
申请号：US18327614
申请日：2023-06-01
Inventor： William R. Taylor , John B. Kisiel , Douglas W. Mahoney , David A. Ahlquist , Hatim T. Allawi , Michael W. Kaiser
IPC: C12Q1/6886 , C12N15/117 , C12Q1/6869 , G01N33/50
CPC classification number: C12Q1/6886 , C12N15/117 , C12Q1/6869 , G01N33/50 , C12Q2521/301 , C12Q2523/125
Abstract: Provided herein is technology for ovarian cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of ovarian cancer and sub-types of ovarian cancer (e.g., clear cell ovarian cancer, endometrioid ovarian cancer, mucinous ovarian cancer, serous ovarian cancer).
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公开(公告)号：US11821039B2
公开(公告)日：2023-11-21
申请号：US15930267
申请日：2020-05-12
Inventor： David A. Ahlquist , John B. Kisiel , William R. Taylor , Tracy C. Yab , Douglas W. Mahoney , Graham P. Lidgard , Hatim T. Allawi
IPC: C07H21/04 , C12Q1/68 , C12Q1/6886
CPC classification number: C12Q1/6886 , C12Q2600/112 , C12Q2600/154
Abstract: Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.
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公开(公告)号：US20230357852A1
公开(公告)日：2023-11-09
申请号：US18021861
申请日：2021-08-18
Applicant: Mayo Foundation for Medical Education and Research , EXACT SCIENCES DEVELOPMENT COMPANY, LLC
Inventor： John B. Kisiel , Douglas W. Mahoney , David A. Ahlquist , William R. Taylor , Hatim T. Allawi , Viatcheslav E. Katerov
IPC: C12Q1/6886
CPC classification number: C12Q1/6886 , C12Q2600/154
Abstract: Provided herein is technology for cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of non-Hodgkin lymphoma (NHL) and NHL subtypes (e.g., diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, mantle cell lymphoma, marginal zone lymphoma, peripheral T-cell lymphoma).
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