摘要:
A vapor permeation method and apparatus for removing a vapor from a vaporous feed stream, the method and apparatus utilizing highly solvent-resistant composite hollow fiber membranes and a permeate flow countercurrent to the feed flow, wherein the support of the composite membrane is formed by solution casting and has been rendered sufficiently solvent-resistant by a post-casting step to retain at least 20 of its burst pressure when soaked in the solvent used to cast the support.
摘要:
An asymmetric microporous membrane with exceptional solvent resistance and highly desirable permeability is disclosed. The membrane is made by a solution-casting or solution-spinning process from a copolyamic acid comprising the condensation reaction product in a solvent of at least three reactants selected from certain diamines and dianhydrides and post-treated to imidize and in some cases cross-link the copolyamic acid. The membrane is useful as an uncoated membrane for ultrafiltration, microfiltration, and membrane contactor applications, or may be used as a support for a permselective coating to form a composite membrane useful in gas separations, reverse osmosis, nanofiltration, pervaporation, or vapor permeation.
摘要:
A process for the dehydration of a vaporous mixture. The basic process involves directing a predominantly condensable water vapor-containing vaporous mixture against the feed side of a membrane while maintaining the feed near saturation without condensing it, directing a condensable vapor sweep stream past the permeate side of the membrane in a countercurrent flow, thereby transporting water vapor in the vaporous mixture from the feed side to the permeate side of the membrane to form a noncondensed combined permeate side mixture of condensable vapor and transported water vapor.
摘要:
A process for the removal of at least one non-water vapor component of a vaporous mixture, the basic process comprising directing a vaporous mixture against the feed side of a membrane, directing a condensable vapor sweep stream past the permeate side of the membrane in a manner such that the flow of the condensable vapor sweep is substantially countercurrent to the flow of the vaporous mixture, thereby transporting at least a portion of at least one non-water vapor component of the vaporous mixture from the feed side to the permeate side of the membrane to form a combined permeate side mixture of condensable vapor and at least one non-water vapor transported component.
摘要:
There are disclosed saltmen-type metallo Schiff base complexes and oxygen-sorbing and -desorbing solutions of the same, pressure- and temperature-swing oxygen separation processes using the complexes and solutions, and methods of regenerating such complexes and solutions.
摘要:
Sensors responsive to small changes in the concentration of chemical species are disclosed, comprising a mechanicochemically responsive polymeric film capable of expansion or contraction in response to a change in its chemical environment, either operatively coupled to a transducer capable of directly converting the expansion or contraction to a measurable electrical or optical response, or adhered to a second inert polymeric strip, or doped with a conductive material.
摘要:
Composite cellulosic semipermeable membranes are disclosed which are the covalently bonded reaction product of an asymmetric cellulosic semipermeable membrane and a polysiloxane containing reactive functional groups. The two reactants chemically bond by ether, ester, amide or acrylate linkages to form a siloxane-grafted cellulosic membrane having superior selectivity and flux stability. Selectivity may be enhanced by wetting the surface with a swelling agent such as water.
摘要:
The process comprises delivering a spray solution comprising an active agent and a matrix material in an organic solvent to a spray-drying apparatus, atomizing the spray solution into droplets within the spray-drying apparatus to remove at least a portion of the organic solvent from the droplets to form a plurality of particles, and collecting the particles. The spray solution may be formed by forming a feed suspension comprising the active agent, the matrix material, and the organic solvent, wherein the feed suspension is at a temperature T1, and directing the feed suspension to a heat exchanger, thereby increasing the temperature of the feed suspension to a temperature T2, wherein T2 is greater than T1, and the spray solution is at a pressure greater than the vapor pressure of the organic solvent at T2, such that the active agent and matrix material are soluble in the organic solvent at T2.
摘要:
The process comprises delivering a spray solution comprising at least one solute in a solvent to a spray-drying apparatus, using a flash nozzle to atomize the spray solution into droplets within the spray-drying apparatus to remove at least a portion of the solvent from the droplets to form a plurality of particles, and collecting the particles. The spray solution is directed to a heat exchanger, thereby increasing the temperature of the spray solution to a temperature T2, wherein T2 is greater than T1. The flash nozzle comprises a central tube through which the spray solution is delivered and an outer tube through which a sweep gas is delivered. The central tube may have a first outer diameter at an inlet and a second outer diameter at an outlet, wherein the first outer diameter is greater than the second outer diameter.
摘要:
High loading immediate release dosage forms containing at least 30 wt % of a solid drug dispersion, at least 5 wt % of a disintegrant and a porosigen are disclosed that exhibit excellent strength and aqueous solubility.