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公开(公告)号：US10395777B2
公开(公告)日：2019-08-27
申请号：US15997654
申请日：2018-06-04
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Inti Pedroso , Catalina Valdivia , Rodrigo Ortiz , Paz Tapia
Abstract: Embodiments of a method and/or system for characterizing one or more sleep-related conditions can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process associated with the one or more sleep-related conditions, based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing a sleep-related characterization process for the one or more sleep-related conditions, and/or determining one or more therapies S140.
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公开(公告)号：US10383519B2
公开(公告)日：2019-08-20
申请号：US15815622
申请日：2017-11-16
Applicant: uBiome, Inc
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
IPC: G01N33/48 , A61B5/00 , C12Q1/689 , G06F19/00 , G16B40/00 , G16B50/00 , G16H50/20 , G16H50/80 , G06G7/58
Abstract: A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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83.发明授权公开(公告)号：US10381112B2
公开(公告)日：2019-08-13
申请号：US15844360
申请日：2017-12-15
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Catalina Valdivia , Rodrigo Ortiz , Inti Pedroso , Victoria Dumas , Paz Tapia , Eduardo Morales
Abstract: Embodiments of a method and/or system for characterizing an allergy-related condition for a user can include one or more of: generating a microbiome dataset for each of an aggregate set of biological samples associated with a population of subjects, based on sample processing of the biological samples; processing a supplementary dataset associated with one or more allergy-related conditions for the set of users; and performing an allergy-related characterization process for the one or more allergy-related conditions, based on the supplementary dataset and/or microbiome features extracted from the microbiome dataset.
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84.发明授权公开(公告)号：US10360348B2
公开(公告)日：2019-07-23
申请号：US15621445
申请日：2017-06-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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85.发明授权公开(公告)号：US10360347B2
公开(公告)日：2019-07-23
申请号：US15621398
申请日：2017-06-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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Patent Agency Ranking
公开(公告)号：US10360346B2
公开(公告)日：2019-07-23
申请号：US15606824
申请日：2017-05-26
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid
IPC: G01N33/48 , G06F19/00 , G16B50/00 , C12Q1/68 , C12Q1/6883 , C12Q1/689 , G16H50/20 , G16H20/10 , G16B99/00 , G16B5/00 , G06G7/58
Abstract: A method for diagnosing and treating an immune microbial dysfunction in a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the immune microbial dysfunction based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset, wherein the characterization is diagnostic of at least one of Crohn's disease, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), ulcerative colitis, and celiac disease; based upon the characterization, generating a therapy model configured to correct the immune microbial dysfunction; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号：US10354756B2
公开(公告)日：2019-07-16
申请号：US15849041
申请日：2017-12-20
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
Abstract: A method for at least one of characterizing, diagnosing, and treating a cutaneous condition in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the cutaneous condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the cutaneous condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号：US10325685B2
公开(公告)日：2019-06-18
申请号：US15844139
申请日：2017-12-15
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Catalina Valdivia , Rodrigo Ortiz , Inti Pedroso , Victoria Dumas , Paz Tapia , Eduardo Morales
Abstract: Embodiments of a method and/or system for characterizing a diet-related condition for a user can include one or more of: generating a microbiome dataset for each of an aggregate set of biological samples associated with a population of subjects, based on sample processing of the biological samples; processing a supplementary dataset associated with one or more diet-related conditions for the set of users; and performing a diet-related characterization process for the one or more diet-related conditions, based on the supplementary dataset and/or microbiome features extracted from the microbiome dataset.
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89.发明授权公开(公告)号：US10325071B2
公开(公告)日：2019-06-18
申请号：US15621363
申请日：2017-06-13
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Daniel Almonacid , Jessica Richman
Abstract: A method for at least one of characterizing, diagnosing and treating a neurological health issue in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the neurological health issue based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the neurological health issue; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
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公开(公告)号：US20190136288A1
公开(公告)日：2019-05-09
申请号：US16182482
申请日：2018-11-06
Applicant: uBiome, Inc.
Inventor： Zachary Apte , Jessica Richman , Daniel Almonacid , Patricia Vera , Elisabeth M. Bik , Amanda Morton , Tomas Norambuena , Rodrigo Ortiz
IPC: C12Q1/06
Abstract: Embodiments of a method and/or system, such as for improving a microorganism-related characterization process, can include: preparing a set of control samples (e.g., from an individual specimen); determining one or more reference microorganism-related parameters (e.g., cutoff reference ranges of relative abundance for a set of microorganism taxa) based on one or more control samples of the set of control samples; and determining one or more variability parameters for the microorganism-related characterization based on the one or more reference microorganism-related parameters and one or more control sample characterizations for one or more control samples of the set of control samples.
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