公开(公告)号：US20240100345A1

公开(公告)日：2024-03-28

申请号：US18267686

申请日：2021-12-15

Applicant: Galvani Bioelectronics Limited

Inventor： Eric Irwin

IPC: A61N1/375 ,  A61B17/04 ,  A61B17/10 ,  A61B17/34 ,  A61N1/05

CPC classification number: A61N1/37518 ,  A61B17/0469 ,  A61B17/10 ,  A61B17/3468 ,  A61N1/0507 ,  A61B2017/320044

Abstract: A method of inserting and affixing an implant by making an incision in an abdominal wall is disclosed. A subcutaneous pocket is formed between a first layer of the abdominal wall and a second layer of the abdominal wall, such that the pocket is at least 2 centimeters from the costal margin. An implant is placed into the subcutaneous pocked and affixed within the subcutaneous pocket in the abdominal wall.

公开(公告)号：USD994595S1

公开(公告)日：2023-08-08

申请号：US29826935

申请日：2022-02-16

Applicant: Galvani Bioelectronics Limited

Designer： Jay Canham ,  David Lari ,  Cindy Au ,  Melissa Lara ,  Daniel Nobre ,  Ryan Jongwoo Choi

Abstract: FIG. 1 is a top perspective view of a charger;
FIG. 2 is a bottom perspective view thereof;
FIG. 3 is top plan view thereof;
FIG. 4 is a bottom plan view thereof;
FIG. 5 is a front elevation view thereof;
FIG. 6 is a right side elevation view thereof;
FIG. 7 is a left side elevation view thereof; and,
FIG. 8 is a rear elevation view thereof.
The broken lines in the drawings are for the purpose of illustrating portions of the charger that form no part of the claimed design.

公开(公告)号：US11633601B2

公开(公告)日：2023-04-25

申请号：US16955282

申请日：2018-12-20

Applicant: Galvani Bioelectronics Limited

Inventor： Margarita J. Vervoordeldonk ,  Robert Coatney ,  Cindy Cleypool

IPC: A61N1/05 ,  A61N1/36

Abstract: Modulation of the neural activity of a nerve adjacent to the left gastro epiploic artery (LGEA) and/or a nerve adjacent to a short gastric artery (SGA) can modulate the neural activity of the sympathetic nerves that impact splenic function. This is useful for reducing inflammation and providing ways of treating inflammatory disorders.

公开(公告)号：US20230059066A1

公开(公告)日：2023-02-23

申请号：US17782559

申请日：2020-12-09

Applicant: Galvani Bioelectronics Limited ,  Duke University

Inventor： Arun Sridhar ,  Philip Milliken ,  Christopher Lawrence Langdale ,  Warren Murray Grill ,  James Arthur Hokanson

IPC: A61N1/36

Abstract: The present disclosure provides an apparatus for stimulating neural activity in a pudendal nerve of a subject, the apparatus comprising of: at least one primary electrode configured to apply a first electrical signal to said nerve; and a controller coupled to said primary electrode (s) and controlling the first electrical signal to be applied thereby, wherein said controller is configured to cause said at least one primary electrode to apply said first electrical signal that stimulates neural activity in the pudendal nerve to improve bladder function, and wherein the first electrical signal is applied in a burst pattern.

公开(公告)号：US11583685B2

公开(公告)日：2023-02-21

申请号：US16955362

申请日：2018-12-21

Applicant: Galvani Bioelectronics Limited

Inventor： Eric Irwin ,  Andrew Hindmarsh ,  John Bennett

IPC: A61N1/375 ,  A61B17/3209 ,  A61N1/378 ,  A61B17/29 ,  A61B18/00 ,  A61B17/00 ,  A61B17/295

Abstract: An implantation system and methods of inserting an implant are disclosed. The method includes the step of making an incision in an abdominal wall with an instrument positioned within an abdominal cavity. The method further includes the steps of forming a pocket between a first surface of the abdominal wall and a second surface of the abdominal wall, such that the incision defines an opening into the pocket, inserting an implant through the opening and into the pocket, and closing the opening such that the implant is captured within the pocket.

公开(公告)号：US20230030204A1

公开(公告)日：2023-02-02

申请号：US17967436

申请日：2022-10-17

Applicant: Galvani Bioelectronics Limited ,  Centre Nationale de La Recherche Scientifique ,  Université Côte d'Azur

Inventor： Arun Sridhar ,  Philippe Blancou ,  Nicolas Glaichenhaus

IPC: A61N1/36 ,  A61N1/05

Abstract: Modulation of neural signaling of a pancreas-related sympathetic nerve is capable of improving glycaemic control by inhibiting T cell activation or migration to the pancreas, and hence providing a way of treating or preventing type 1 diabetes.

公开(公告)号：US20230021801A1

公开(公告)日：2023-01-26

申请号：US17782539

申请日：2020-12-09

Applicant: Galvani Bioelectronics Limited

Inventor： Arun Sridhar ,  Philip Milliken

IPC: A61N1/36

Abstract: Provided herein is a solution to the problem of stimulation of a target pudendal nerve such that the stimulation applied by the electrode at that position selectively modulates the external urtheral sphincter (EUS), or selectively modulates the external anal sphincter (EAS).

公开(公告)号：US11559692B2

公开(公告)日：2023-01-24

申请号：US16634620

申请日：2018-07-23

Applicant: GALVANI BIOELECTRONICS LIMITED

Inventor： Faisal Zaidi ,  Sebastien Ouchouche

IPC: A61N1/05 ,  A61N1/372 ,  A61K31/56 ,  A61N1/375

Abstract: An extravascular neural interface is disclosed containing electrodes for neurostimulation of the vessel. The devices are housed in flexible substrates, each substrate having a spinal portion for routing leads/conductors into the device for connection to the electrodes. Extending from opposite sides of the spinal portion is a self-sizing inner flap that supports and positions the electrodes to be inward facing, i.e., extravascular designs, and one more rigid outer flap. The electrodes may be flexible multifilar coil electrodes.

公开(公告)号：US20220401734A1

公开(公告)日：2022-12-22

申请号：US17872319

申请日：2022-07-25

Applicant: Galvani Bioelectronics Limited

Inventor： Matteo Donega ,  Daniel John Chew ,  Isha Gupta

IPC: A61N1/36 ,  A61N1/05

Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is associated with a neurovascular bundle, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating inflammatory disorders. The invention provides improved ways of treating inflammatory disorders which minimize off-target effects.

公开(公告)号：US20220355102A1

公开(公告)日：2022-11-10

申请号：US17595169

申请日：2020-05-07

Applicant: Cindy AU ,  GALVANI BIOELECTRONICS LIMITED

Inventor： Cindy AU

IPC: A61N1/05 ,  B29C45/16 ,  B29C45/14

Abstract: A method for use in making an electrode assembly (20) comprises the steps of applying an electrode (24) on a first layer of material (22); laser welding a lead (23) to the electrode; applying an adhesive backfill (26) over the electrode and the lead; and applying a second layer of material (28) over the adhesive backfill and a portion of the first layer to prevent a leakage path between the electrode and the second layer.