公开(公告)号：US08401214B2

公开(公告)日：2013-03-19

申请号：US12818449

申请日：2010-06-18

申请人： Rodney C. Perkins ,  Sunil Puria

发明人： Rodney C. Perkins ,  Sunil Puria

IPC分类号： H04R25/00

CPC分类号： H04R25/606 ,  A61F11/002 ,  H04R1/10 ,  H04R25/60 ,  H04R2460/13

摘要： An implantable device is configured for placement in the eardrum to transmit an audio signal to a user. The device may be configured to improve transmission of an electromagnetic signal including light energy from an input assembly on a lateral side of eardrum to an output assembly positioned on a medial side of the eardrum, for example at least partially in the middle ear of the user. The output assembly may include a transducer or at least two electrodes configured to stimulate the cochlea, for example. The device may include an opening to transmit the light signal or an optic to transmit the light signal. Alternatively the device may be configured to support a transducer of the output assembly with the eardrum when the device is implanted in the eardrum, such that the eardrum vibrates in response to the signal electromagnetic signal. The electromagnetic signal may include light energy for a magnetic field.

摘要翻译： 可植入装置被配置为放置在鼓膜中以向用户传输音频信号。 该装置可以被配置为改善包括来自鼓膜侧面上的输入组件的光能的电磁信号的传输到定位在鼓膜的内侧上的输出组件，例如至少部分地在使用者的中耳 。 输出组件可以包括例如换能器或构造成刺激耳蜗的至少两个电极。 该装置可以包括用于传输光信号的开口或光学器件以传输光信号。 或者，该装置可以被配置为当该装置植入鼓膜时，用鼓膜支撑输出组件的换能器，使得该鼓膜响应于该信号电磁信号而振动。 电磁信号可以包括用于磁场的光能。

公开(公告)号：US20120253267A1

公开(公告)日：2012-10-04

申请号：US13429087

申请日：2012-03-23

申请人： DON C. REED ,  SEAMUS O'LOAN

发明人： DON C. REED ,  SEAMUS O'LOAN

IPC分类号： A61M25/14 ,  A61D7/00 ,  A61M1/00

CPC分类号： A61F11/002 ,  A61B1/227 ,  A61M1/0003 ,  A61M1/0062 ,  A61M1/0064 ,  A61M3/0254 ,  A61M2210/0662

摘要： A method of treating a mammal presenting with an otic infection attributable to a pathogenic bacteria is accomplished by passing a hollow shaft having a first and second end through the tympanum of the mammal. The first end is sufficient to pierce the tympanic membrane, but flexible enough such that it buckles under the force necessary to damage any surrounding tissues in the tympanic cavity. The first end of the hollow shaft, after it pierces the tympanic membrane, extends into the tympanic cavity to aspirate a volume of effluence contained therein. The aspirated effluence is expelled out the second end of the hollow shaft. A volume of medicament (less than the volume of effluence withdrawn) is then injected through the same hollow shaft and into the tympanic cavity to treat the infection.

摘要翻译： 通过将具有第一和第二端的空心轴穿过哺乳动物的鼓膜来实现治疗呈现出归因于致病细菌的耳部感染的哺乳动物的方法。 第一端足以刺穿鼓膜，但足够灵活，使其在损伤鼓室周围组织所必需的力下弯曲。 空心轴的第一端在刺穿鼓膜后延伸到鼓室中以吸收其中所含的一定量的流出物。 吸出的流出物从空心轴的第二端排出。 然后通过相同的空心轴将一定体积的药物（小于排出的体积）注入鼓室以治疗感染。

公开(公告)号：US08197433B2

公开(公告)日：2012-06-12

申请号：US11917751

申请日：2006-06-15

申请人： David Cohen

发明人： David Cohen

IPC分类号： A61M5/00

CPC分类号： A61F11/002

摘要： The invention provides a flexible ear tube (10) for draining and ventilating the middle ear, the tube (10) having a flexible substantially tubular stem (12) with a lumen (14), the stem (12) being sized to be inserted through an incision in the eardrum (16) and the tube having at least two separate flexible contact surfaces (18) extending from the stem (12) and adapted to engage different spaced-apart inner surfaces of the eardrum 16, each of the contact surfaces (18) having a first axis XX extending substantially perpendicularly to the central axis of the stem and a second axis YY extending substantially perpendicularly to the first axis wherein one of the axes is between 0.6 and 3 mm and the second of the axes is between 1 and 7 mm in length.

摘要翻译： 本发明提供了一种用于排出和通风中耳的柔性耳管（10），所述管（10）具有带有内腔（14）的柔性基本上管状的杆（12），所述杆（12）的尺寸设置成插入通过 在鼓膜（16）中的切口和具有从杆（12）延伸的至少两个单独的柔性接触表面（18）的管，并且适于接合鼓膜16的不同间隔开的内表面，每个接触表面 18）具有基本上垂直于所述杆的中心轴线延伸的第一轴线XX和大致垂直于所述第一轴线延伸的第二轴线YY，其中所述轴线之一在0.6和3mm之间，并且所述第二轴线在1和 长7毫米。

公开(公告)号：US08147545B2

公开(公告)日：2012-04-03

申请号：US12666586

申请日：2008-06-26

申请人： Galit Avior

发明人： Galit Avior

IPC分类号： A61F2/18

CPC分类号： A61F11/002

摘要： The present invention provides a device stenting the ET. The stent (device) provides enhanced ventilation and drainage to the middle ear. Also provided is a method for inserting the device into the Eustachian tube and through the isthmus of a human subject.

摘要翻译： 本发明提供一种支架植入ET的装置。 支架（装置）为中耳提供增强的通气和排水。 还提供了一种用于将装置插入咽鼓管并通过人类受试者的峡部的方法。

公开(公告)号：US08123722B2

公开(公告)日：2012-02-28

申请号：US11926467

申请日：2007-10-29

申请人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  Theodore C. Lamson ,  Amrish Jayprakash Walke

发明人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  Theodore C. Lamson ,  Amrish Jayprakash Walke

IPC分类号： A61M29/00

CPC分类号： A61F11/002 ,  A61B5/065 ,  A61B10/06 ,  A61B17/1204 ,  A61B17/12045 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/1604 ,  A61B17/1608 ,  A61B17/1679 ,  A61B17/1688 ,  A61B17/24 ,  A61B17/32002 ,  A61B17/32075 ,  A61B17/3478 ,  A61B34/20 ,  A61B50/13 ,  A61B50/15 ,  A61B50/20 ,  A61B90/16 ,  A61B90/361 ,  A61B2017/00247 ,  A61B2017/003 ,  A61B2017/320004 ,  A61B2017/3486 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2034/2051 ,  A61F2/958 ,  A61F2250/0067 ,  A61M25/007 ,  A61M25/10 ,  A61M2025/105 ,  A61M2025/1052

摘要： Sinusitis, mucocysts, tumors, infections, hearing disorders, choanal atresia, fractures and other disorders of the paranasal sinuses, Eustachian tubes, Lachrymal ducts and other ear, nose, throat and mouth structures are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies and endoscopic studies. Access and occluding devices may be used to facilitate insertion of working devices such asendoscopes, wires, probes, needles, catheters, balloon catheters, dilation catheters, dilators, balloons, tissue cutting or remodeling devices, suction or irrigation devices, imaging devices, sizing devices, biopsy devices, image-guided devices containing sensors or transmitters, electrosurgical devices, energy emitting devices, devices for injecting diagnostic or therapeutic agents, devices for implanting devices such as stents, substance eluting or delivering devices and implants, etc.

摘要翻译： 鼻窦炎，粘膜囊肿，肿瘤，感染，听力障碍，胆管闭锁，鼻旁窦的骨折和其他疾病，咽鼓管，泪道和其他耳，鼻，喉和嘴结构被诊断和/或使用微创方法治疗， 在许多情况下，柔性导管与具有刚性轴的仪器相反。 使用各种诊断程序和装置进行成像研究，粘液流动研究，空气/气体流动研究，解剖维度研究和内窥镜研究。 可以使用进入和闭塞装置以便于诸如内窥镜，电线，探针，针，导管，球囊导管，扩张导管，扩张器，球囊，组织切割或重塑装置等工作装置的插入，抽吸或冲洗装置，成像装置，定径装置 ，活检装置，包含传感器或发射器的图像引导装置，电外科装置，能量发射装置，用于注射诊断或治疗剂的装置，用于植入诸如支架的装置，物质洗脱或递送装置和植入物等的装置。

公开(公告)号：US08088101B2

公开(公告)日：2012-01-03

申请号：US11925357

申请日：2007-10-26

申请人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  Theodore C. Lamson ,  Amrish Jayprakash Walke

发明人： John Y. Chang ,  Joshua Makower ,  Julia D. Vrany ,  Theodore C. Lamson ,  Amrish Jayprakash Walke

IPC分类号： A61M29/00

CPC分类号： A61F11/002 ,  A61B5/065 ,  A61B10/06 ,  A61B17/1204 ,  A61B17/12045 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/1604 ,  A61B17/1608 ,  A61B17/1679 ,  A61B17/1688 ,  A61B17/24 ,  A61B17/32002 ,  A61B17/32075 ,  A61B17/3478 ,  A61B34/20 ,  A61B50/13 ,  A61B50/15 ,  A61B50/20 ,  A61B90/16 ,  A61B90/361 ,  A61B2017/00247 ,  A61B2017/003 ,  A61B2017/320004 ,  A61B2017/3486 ,  A61B2017/3488 ,  A61B2018/00392 ,  A61B2034/2051 ,  A61F2/958 ,  A61F2250/0067 ,  A61M25/007 ,  A61M25/10 ,  A61M2025/105 ,  A61M2025/1052

摘要： Sinusitis, mucocysts, tumors, infections, hearing disorders, choanal atresia, fractures and other disorders of the paranasal sinuses, Eustachian tubes, Lachrymal ducts and other ear, nose, throat and mouth structures are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies and endoscopic studies. Access and occluding devices may be used to facilitate insertion of working devices such as endoscopes, wires, probes, needles, catheters, balloon catheters, dilation catheters, dilators, balloons, tissue cutting or remodeling devices, suction or irrigation devices, imaging devices, sizing devices, biopsy devices, image-guided devices containing sensors or transmitters, electrosurgical devices, energy emitting devices, devices for injecting diagnostic or therapeutic agents, devices for implanting devices such as stents, substance eluting or delivering devices and implants, etc.

摘要翻译： 鼻窦炎，粘膜囊肿，肿瘤，感染，听力障碍，胆管闭锁，鼻旁窦的骨折和其他疾病，咽鼓管，泪道和其他耳，鼻，喉和嘴结构被诊断和/或使用微创方法治疗， 在许多情况下，柔性导管与具有刚性轴的仪器相反。 使用各种诊断程序和装置进行成像研究，粘液流动研究，空气/气体流动研究，解剖维度研究和内窥镜研究。 可以使用进入和闭塞装置来促进诸如内窥镜，电线，探针，针，导管，球囊导管，扩张导管，扩张器，球囊，组织切割或重塑装置等工作装置的插入，抽吸或冲洗装置，成像装置，尺寸 装置，活检装置，包含传感器或发射器的图像引导装置，电外科装置，能量发射装置，用于注射诊断或治疗剂的装置，用于植入诸如支架，物质洗脱或递送装置和植入物等装置的装置等。

公开(公告)号：US07978742B1

公开(公告)日：2011-07-12

申请号：US12730482

申请日：2010-03-24

申请人： Dmitri Vladislavovich Kuksenkov ,  Shenping Li

发明人： Dmitri Vladislavovich Kuksenkov ,  Shenping Li

IPC分类号： H01S3/00

CPC分类号： A61F11/002 ,  H01S5/0602 ,  H01S5/06251 ,  H01S5/06256

摘要： Methods for operating diode lasers are provided. According to one method, the diode laser comprises a wavelength selection section, a gain section and a saturable absorber. The method comprises applying a hybrid-control signal comprising a hybrid-control DC bias to the saturable absorber, and applying a hybrid-driving signal comprising a hybrid-driving DC bias and a hybrid-driving AC bias to the gain section. The hybrid signals are selected and the diode laser is configured such that a relatively high hybrid-control DC bias corresponds to a relatively low average of the output power of the diode laser, and a relatively low hybrid-control DC bias corresponds to a relatively high average of the output power of the diode laser. The hybrid-driving DC bias is between a switch-on threshold of the diode laser and a switch-off threshold of the diode laser, and the hybrid-driving AC bias is periodic. The hybrid-driving AC bias has a peak-to-peak amplitude greater than the difference between the switch-on threshold and the switch-off threshold.

摘要翻译： 提供了操作二极管激光器的方法。 根据一种方法，二极管激光器包括波长选择部分，增益部分和饱和吸收体。 该方法包括将包括混合控制DC偏置的混合控制信号施加到可饱和吸收器，以及将包括混合驱动DC偏置和混合驱动AC偏置的混合驱动信号施加到增益部分。 选择混合信号，并且二极管激光器被配置为使得相对高的混合控制DC偏压对应于二极管激光器的输出功率的相对较低的平均值，并且相对低的混合控制DC偏压对应于相对较高的 平均二极管激光器的输出功率。 混合驱动DC偏压在二极管激光器的接通阈值和二极管激光器的关断阈值之间，并且混合驱动AC偏压是周期性的。 混合驱动AC偏压具有比接通阈值和关断阈值之间的差大的峰 - 峰幅度。

公开(公告)号：US20110142274A1

公开(公告)日：2011-06-16

申请号：US12818449

申请日：2010-06-18

申请人： Rodney C. Perkins ,  Sunil Puria

发明人： Rodney C. Perkins ,  Sunil Puria

IPC分类号： H04R25/00

CPC分类号： H04R25/606 ,  A61F11/002 ,  H04R1/10 ,  H04R25/60 ,  H04R2460/13

摘要： An implantable device is configured for placement in the eardrum to transmit an audio signal to a user. The device may be configured to improve transmission of an electromagnetic signal comprising light energy from an input assembly on a lateral side of eardrum to an output assembly positioned on a medial side of the eardrum, for example at least partially in the middle ear of the user. The output assembly may comprise a transducer or at least two electrodes configured to stimulate the cochlea, for example. The device may comprise an opening to transmit the light signal or an optic to transmit the light signal. Alternatively the device may be configured to support a transducer of the output assembly with the eardrum when the device is implanted in the eardrum, such that the eardrum vibrates in response to the signal electromagnetic signal. The electromagnetic signal may comprise light energy for a magnetic field.

摘要翻译： 可植入装置被配置为放置在鼓膜中以向用户传输音频信号。 该装置可以被配置为改进包括来自鼓膜侧面上的输入组件的光能的电磁信号的传输到定位在鼓膜的内侧上的输出组件，例如至少部分地在使用者的中耳 。 输出组件可以包括例如换能器或构造成刺激耳蜗的至少两个电极。 该装置可以包括用于传输光信号的开口或用于传输光信号的光学器件。 或者，该装置可以被配置为当该装置植入鼓膜时，用鼓膜支撑输出组件的换能器，使得该鼓膜响应于该信号电磁信号而振动。 电磁信号可以包括用于磁场的光能。

公开(公告)号：US20110066176A1

公开(公告)日：2011-03-17

申请号：US12561464

申请日：2009-09-17

申请人： William Coole ,  Lawrence G. Clayton

发明人： William Coole ,  Lawrence G. Clayton

IPC分类号： A61M29/02

CPC分类号： A61F2/18 ,  A61B17/56 ,  A61F11/00 ,  A61F11/002 ,  A61F11/08 ,  A61F11/10 ,  A61F2002/183 ,  A61F2011/085 ,  A61F2210/0014 ,  A61F2230/0069 ,  A61H39/04 ,  A61H2201/168 ,  A61H2205/027 ,  A61M2210/0662 ,  A61M2210/0668

摘要： An expansible ear canal insert for treating TMJ disorders and headaches which acts directly on the TMJ and associated ligament and muscle structures to reduce stress and loads placed on the articulator disc located between the temporal bone and the mandible, as well as supportive muscles and ligaments near the TMJ. The insert is adapted to expand by application of body heat. In the expanded condition, the insert provides support to the TMJ and associated ligament and muscle structures.

摘要翻译： 用于治疗TMJ疾病和头痛的可扩展耳道插入物，其直接作用于TMJ和相关韧带和肌肉结构，以减轻放置在颞骨和下颌骨之间的咬合器盘上的应力和负荷，以及附近的支撑肌肉和韧带 TMJ。 插入件适于通过施加体热而膨胀。 在扩张状态下，插入物可以为TMJ和相关的韧带和肌肉结构提供支持。

公开(公告)号：US20100174366A1

公开(公告)日：2010-07-08

申请号：US12666586

申请日：2008-06-26

申请人： Galit Avior

发明人： Galit Avior

IPC分类号： A61F2/18

CPC分类号： A61F11/002

摘要： The present invention provides a device stenting the ET. The stent (device) provides enhanced ventilation and drainage to the middle ear. Also provided is a method for inserting the device into the Eustachian tube and through the isthmus of a human subject.

摘要翻译： 本发明提供一种支架植入ET的装置。 支架（装置）为中耳提供增强的通气和排水。 还提供了一种用于将装置插入咽鼓管并通过人类受试者的峡部的方法。