公开(公告)号：US07505559B2

公开(公告)日：2009-03-17

申请号：US11510062

申请日：2006-08-25

Applicant: Gopinath R. Kuduvalli

Inventor： Gopinath R. Kuduvalli

IPC: A61N5/10

CPC classification number: A61N5/1049 ,  A61N5/1048 ,  A61N5/1067 ,  A61N2005/105 ,  A61N2005/1059 ,  A61N2005/1072

Abstract: An apparatus and method for determining a target-to-surface distance (TSD) between a target region in a body and an actual point of entry of a radiation beam into the body from a radiation source. The method may include determining an absorbed dose of radiation from the radiation beam at the target region using the TSD. The method may also include compensating for both the motion of the target region with respect to the radiation source, and the motion of surrounding tissue relative to the target region. The apparatus may include a sensor system to determine the actual point of entry of the radiation beam into the body.

Abstract translation: 一种用于确定身体中的目标区域与辐射源从辐射源进入体内的实际入射点之间的目标 - 表面距离（TSD）的装置和方法。 该方法可以包括使用TSD确定来自目标区域处的辐射束的辐射的吸收剂量。 该方法还可以包括补偿目标区域相对于辐射源的运动以及周围组织相对于目标区域的运动。 该装置可以包括用于确定辐射束进入体内的实际入射点的传感器系统。

公开(公告)号：US07496174B2

公开(公告)日：2009-02-24

申请号：US11879901

申请日：2007-07-18

Applicant: Michael Gertner ,  Steven D. Hansen ,  Erik Chell

Inventor： Michael Gertner ,  Steven D. Hansen ,  Erik Chell

IPC: A61N5/10

CPC classification number: A61N5/1049 ,  A61B6/506 ,  A61B2017/306 ,  A61F9/009 ,  A61N5/1017 ,  A61N5/103 ,  A61N2005/105 ,  A61N2005/1056 ,  A61N2005/1091

Abstract: A portable orthovoltage radiotherapy system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system.

Abstract translation: 描述了便携式正电压放射治疗系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施例中，将眼部结构置于基于眼睛成像的全局坐标系中。 在一些实施例中，全局坐标系内的目镜结构导致基于坐标系内的眼睛结构而被引导的自动定位系统的方向。

公开(公告)号：US20090013468A1

公开(公告)日：2009-01-15

申请号：US11827320

申请日：2007-07-11

Applicant: Duncan Neil Bourne ,  Ralph Streamer ,  Alan Hitchings

Inventor： Duncan Neil Bourne ,  Ralph Streamer ,  Alan Hitchings

IPC: A61N5/00

CPC classification number: A61N5/1049 ,  A61B6/0457 ,  A61B6/5276 ,  A61N2005/105 ,  A61N2005/1059

Abstract: A patient support system comprises a base, an upstanding support, and a couch attached to the support and having a cantilever section extendable beyond the support; the support including a couch drive means to adjust the position of the couch relative to the support; further comprising a support drive means for translationally driving the support relative to the base in the direction of the cantilever section. This removes inaccuracies from patient position measurements that result from changes in the cantilever geometry during movement of the patient from a measuring position to a treatment position. The support drive means can be located in the base or in the support, and allows the patient support system as a whole to be translated, thereby permitting the patient to be moved into and out of an enclosed treatment area without affecting the vertical location of the patient. The only change to the patient position is in the translational position, which can be calibrated by way of fixed end stops for the support drive means. The present invention further relates to a radiotherapy apparatus, comprising a patient support as set out above, and an enclosed treatment area positioned in line with the cantilever section.

Abstract translation: 患者支撑系统包括底座，直立支撑件和连接到支撑件的沙发，并且具有可延伸超过支撑件的悬臂部分; 包括沙发驱动装置的支撑装置用于调节沙发相对于支撑件的位置; 还包括支撑驱动装置，用于在所述悬臂部分的方向上相对于所述基座平移地驱动所述支撑件。 这消除了患者从测量位置移动到治疗位置的过程中由于悬臂几何形状的变化引起的患者位置测量的不准确性。 支撑驱动装置可以位于基座或支撑件中，并且允许患者支撑系统作为整体被平移，从而允许患者被移入和移出封闭的治疗区域，而不会影响患者的垂直位置 患者。 患者位置的唯一变化是在平移位置，其可以通过用于支撑驱动装置的固定端部止动器进行校准。 本发明还涉及一种放射治疗装置，其包括如上所述的患者支架和与悬臂部分成一直排列的封闭治疗区域。

公开(公告)号：US20080287728A1

公开(公告)日：2008-11-20

申请号：US11748406

申请日：2007-05-14

Applicant: Hassan Mostafavi ,  Andrew G. Jeung

Inventor： Hassan Mostafavi ,  Andrew G. Jeung

IPC: A61N5/02

CPC classification number: A61N5/1049 ,  A61B34/20 ,  A61B90/39 ,  A61B2034/2055 ,  A61B2090/101 ,  A61B2090/3945 ,  A61B2090/3979 ,  A61B2090/3983 ,  A61N5/1037 ,  A61N2005/105 ,  A61N2005/1059

Abstract: A marker system includes a structure having a first surface and a second surface, a first marker located on the first surface, and a second marker located on the second surface, wherein the first marker and the second marker are arranged so that they face approximately a same direction, and so that they can be simultaneously viewed by an optical device, and wherein a first distance between the first marker and the optical device is different from a second distance between the second marker and the optical device when the first and the second markers are simultaneously viewed by the optical device.

Abstract translation: 标记系统包括具有第一表面和第二表面的结构，位于第一表面上的第一标记和位于第二表面上的第二标记，其中第一标记和第二标记被布置成使得它们面对约 相同的方向，并且使得它们可以被光学装置同时观看，并且其中第一标记和光学装置之间的第一距离与第二标记和光学装置之间的第二距离不同时，当第一和第二标记 被光学装置同时观看。

公开(公告)号：US20080212738A1

公开(公告)日：2008-09-04

申请号：US11956295

申请日：2007-12-13

Applicant: Michael GERTNER ,  Steven D. Hansen

Inventor： Michael GERTNER ,  Steven D. Hansen

IPC: A61N5/10

CPC classification number: A61N5/1067 ,  A61B6/506 ,  A61B6/508 ,  A61N5/10 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/1045 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1064 ,  A61N5/1065 ,  A61N5/1077 ,  A61N5/1084 ,  A61N2005/1019 ,  A61N2005/1022 ,  A61N2005/105 ,  A61N2005/1051 ,  A61N2005/1059 ,  A61N2005/1091 ,  A61N2005/1097

Abstract: A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, other disorders or tissues of a body are treated with the dose of radiation. In some embodiments, the target tissues are placed in a global coordinate system based on ocular imaging. In some embodiments, the target tissues inside the global coordinate system lead to direction of an automated positioning system that is directed based on the target tissues within the coordinate system. In some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, a fiducial marker is used to identify the location of the target tissues. In some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments.

Abstract translation: 描述了放射外科系统，其被配置为将治疗剂量的辐射递送到患者中的目标结构。 在一些实施方案中，治疗炎症性眼部疾病，特别是黄斑变性。 在一些实施方案中，身体的其它病症或组织用辐射剂量治疗。 在一些实施例中，目标组织基于眼睛成像被放置在全局坐标系中。 在一些实施例中，全局坐标系统内的目标组织导致基于坐标系统内的目标组织定向的自动定位系统的方向。 在一些实施例中，使用治疗计划，其中针对要治疗的特定疾病和/或要避免的结构确定束能量和治疗时间的方向和持续时间。 在一些实施方案中，使用基准标记来鉴定靶组织的位置。 在一些实施例中，描述了放射外科手术与其他治疗组合使用的放射治疗疗法，并且可以在其它治疗之前，之前或之后进行递送。

公开(公告)号：US20080187097A1

公开(公告)日：2008-08-07

申请号：US11868918

申请日：2007-10-08

Applicant: Chieh C. Cheng ,  David A. Lesyna ,  Michael F. Moyers

Inventor： Chieh C. Cheng ,  David A. Lesyna ,  Michael F. Moyers

IPC: A61N5/10

CPC classification number: A61N5/107 ,  A61B6/0442 ,  A61B6/4092 ,  A61B6/547 ,  A61B2090/3937 ,  A61N5/1037 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/1069 ,  A61N5/1078 ,  A61N2005/105 ,  A61N2005/1059 ,  A61N2005/1061 ,  A61N2005/1062 ,  A61N2005/1087 ,  A61N2005/1097 ,  B25J9/1666 ,  G05B15/02 ,  G05B2219/45117

Abstract: A patient positioning system for use with a radiation therapy system that monitors the location of fixed and movable components and pre-plans movement of the movable components so as to inhibit movement if a collision would be indicated. The positioning system can also coordinate movement of multiple movable components for reduced overall latency in registering a patient. The positioning system includes external measurement devices which measure the location and orientation of objects, including components of the radiation therapy system, in space and can also monitor for intrusion into the active area of the therapy system by personnel or foreign objects to improve operational safety of the radiation therapy system.

Abstract translation: 一种与放射治疗系统一起使用的患者定位系统，其监测固定和可移动部件的位置，并预先计划可移动部件的移动，以便在指示碰撞时抑制运动。 定位系统还可以协调多个可移动部件的移动，以减少注册患者时的整体延迟。 定位系统包括外部测量装置，其测量物体的位置和方向，包括放射治疗系统的部件，在空间中，并且还可以监视人员或异物侵入治疗系统的有效区域以提高操作安全性 放射治疗系统。

公开(公告)号：US07173265B2

公开(公告)日：2007-02-06

申请号：US10917022

申请日：2004-08-12

Applicant: Daniel W. Miller ,  Steve K. McAllaster ,  Jerry D. Slater ,  Nickolas S. Rigney ,  Daniel C. Anderson ,  Michael F. Moyers

Inventor： Daniel W. Miller ,  Steve K. McAllaster ,  Jerry D. Slater ,  Nickolas S. Rigney ,  Daniel C. Anderson ,  Michael F. Moyers

IPC: A61N5/10

CPC classification number: A61N5/107 ,  A61B6/0442 ,  A61B6/4092 ,  A61B6/547 ,  A61B2090/3937 ,  A61N5/1037 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/1069 ,  A61N5/1078 ,  A61N2005/105 ,  A61N2005/1059 ,  A61N2005/1061 ,  A61N2005/1062 ,  A61N2005/1087 ,  A61N2005/1097 ,  B25J9/1666 ,  G05B15/02 ,  G05B2219/45117

Abstract: A radiation treatment system (100) for accurately delivering radiation to a targeted site within a cancer patient (108) that includes a modular patient support system and a patient positioner (114). The modular patient support system includes a modularly expandable patient pod (200) and at least one immobilization device, such as, for example, a rigid moldable foam cradle (350). The patient pod (200) includes a generally hemi-cylindrical support shell (212) that extends longitudinally between proximal edge (214) and distal edge (216), and transversely between two lateral edges (222, 224). In one embodiment, the lateral edges (222, 224) are tapered to minimize edge effects that result when radiation beams traverse the lateral edges (222, 224).

Abstract translation: 1.一种辐射治疗系统（100），用于将辐射准确地传送到癌症患者（108）内的目标部位，其包括模块化患者支撑系统和患者定位器（114）。 模块化患者支撑系统包括模块化可扩展的患者支架（200）和至少一个固定装置，例如刚性可模制泡沫支架（350）。 患者荚（200）包括在近端边缘（214）和远端边缘（216）之间纵向延伸且横向于两个横向边缘（222,224）之间延伸的大致半圆柱形的支撑壳体（212）。 在一个实施例中，横向边缘（222,224）是锥形的，以最小化当辐射束横穿横向边缘（222,224）时产生的边缘效应。

公开(公告)号：US20060122502A1

公开(公告)日：2006-06-08

申请号：US11005643

申请日：2004-12-06

Applicant: John Scherch ,  Edward Smetak

Inventor： John Scherch ,  Edward Smetak

IPC: A61B5/05

CPC classification number: A61B6/08 ,  A61B6/0492 ,  A61B6/547 ,  A61N5/1049 ,  A61N2005/105 ,  A61N2005/1059

Abstract: A system to analyze the geometry of a radiation treatment apparatus, software, and methods are provided. The system includes an apparatus having a rotating assembly and a trackable body or plurality of trackable bodies, to mark a location of a preselected portion of the rotating assembly. The system also includes a trackable reference fixture and can include a constant orientation trackable body. A determiner determines the position and/or orientation of the trackable bodies, the trackable reference fixture, and constant orientation trackable body. The determiner then determines the geometry of the treatment apparatus to analyze a coordinate system used by an operator. The determiner can have a memory and geometry analyzing software stored in the memory to analyze the treatment apparatus geometry.

Abstract translation: 提供了一种分析辐射处理设备，软件和方法的几何形状的系统。 该系统包括具有旋转组件和可跟踪体或多个可跟踪体的装置，以标记旋转组件的预选部分的位置。 该系统还包括可跟踪参考夹具，并且可以包括恒定定向的可跟踪体。 确定器确定可跟踪物体，可跟踪参考夹具和恒定方向可跟踪体的位置和/或方位。 然后确定器确定处理装置的几何形状以分析操作者使用的坐标系。 确定器可以具有存储在存储器中的存储器和几何分析软件以分析处理装置的几何形状。

公开(公告)号：US20060017022A1

公开(公告)日：2006-01-26

申请号：US10917023

申请日：2004-08-12

Applicant: Nickolas Rigney ,  Daniel Anderson ,  David Lesyna ,  Daniel Miller ,  Michael Moyers ,  Chieh Cheng ,  Michael Baumann

Inventor： Nickolas Rigney ,  Daniel Anderson ,  David Lesyna ,  Daniel Miller ,  Michael Moyers ,  Chieh Cheng ,  Michael Baumann

IPC: G21F5/02

CPC classification number: A61N5/1049 ,  A61B6/0442 ,  A61B6/4092 ,  A61B2090/3937 ,  A61N5/1067 ,  A61N5/1069 ,  A61N5/1078 ,  A61N2005/105 ,  A61N2005/1059 ,  A61N2005/1061 ,  A61N2005/1062 ,  A61N2005/1087 ,  A61N2005/1097 ,  B25J9/1666 ,  G05B15/02 ,  G05B2219/45117

Abstract: A patient alignment system for a radiation therapy system. The alignment system includes multiple external measurement devices which obtain position measurements of components of the radiation therapy system which are movable and/or are subject to flex or other positional variations. The alignment system employs the external measurements to provide corrective positioning feedback to more precisely register the patient and align them with a radiation beam. The alignment system can be provided as an integral part of a radiation therapy system or can be added as an upgrade to existing radiation therapy systems.

公开(公告)号：US20050261570A1

公开(公告)日：2005-11-24

申请号：US10722015

申请日：2003-11-25

Applicant: Timothy Mate ,  Steven Dimmer

Inventor： Timothy Mate ,  Steven Dimmer

IPC: G01V3/00 ,  A61B5/07 ,  A61B19/00 ,  A61N5/10 ,  G01S5/06 ,  G01V15/00 ,  A61B5/05

CPC classification number: A61N5/1049 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/3958 ,  A61N5/107 ,  A61N2005/105 ,  A61N2005/1051

Abstract: A system and method for accurately locating and tracking the position of a target, such as a tumor or the like, within a body. In one embodiment, the system is a target locating and monitoring system usable with a radiation delivery source that delivers selected doses of radiation to a target in a body. The system includes one or more excitable markers positionable in or near the target, an external excitation source that remotely excites the markers to produce an identifiable signal, and a plurality of sensors spaced apart in a known geometry relative to each other. A computer is coupled to the sensors and configured to use the marker measurements to identify a target isocenter within the target. The computer compares the position of the target isocenter with the location of the machine isocenter. The computer also controls movement of the patient and a patient support device so the target isocenter is coincident with the machine isocenter before and during radiation therapy.

Abstract translation: 一种用于在身体内准确定位和跟踪诸如肿瘤等的靶的位置的系统和方法。 在一个实施例中，该系统是可与辐射递送源一起使用的目标定位和监测系统，其将选定剂量的辐射递送到身体中的目标。 该系统包括可定位在靶内或附近的一个或多个可激发标记，远程激发标记以产生可识别信号的外部激发源以及以已知几何形状相对于彼此间隔开的多个传感器。 计算机耦合到传感器并且被配置为使用标记测量来识别目标内的目标等角点。 计算机将目标等角点的位置与机器等角点的位置进行比较。 计算机还控制患者和患者支撑装置的运动，使得目标等角点在辐射治疗之前和放射治疗期间与机器等角点重合。