公开(公告)号：US20160009675A1

公开(公告)日：2016-01-14

申请号：US14771842

申请日：2014-02-25

申请人： ARCHER DANIELS MIDLAND COMPANY

发明人： Alexandra Sanborn ,  Erik Hagberg ,  Stephen Howard ,  Erin M. Rockafellow

IPC分类号： C07D307/50 ,  C07D307/48

CPC分类号： C07D307/48 ,  A61K9/08 ,  A61K31/341 ,  A61K47/10 ,  C07D307/46 ,  C07D307/50 ,  C09K15/06

摘要： Disclosed is a process for making HMF′ or a derivative of HMF by dehydrating one or more hexose sugars in a reduced oxygen environment, in another, related aspect, a method for improving the stability and resistance to degradation of an HMF product Involves adding one or more antioxidants to the HMF product.

摘要翻译： 公开了通过在还原氧环境中脱水一种或多种己糖来制备HMF'或HMF衍生物的方法，另一方面涉及一种用于提高HMF产物的稳定性和抗降解性的方法。 更多抗氧化剂的HMF产品。

公开(公告)号：US20150315663A1

公开(公告)日：2015-11-05

申请号：US14692018

申请日：2015-04-21

申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION

发明人： James A. Dumesic ,  Jeremy S. Luterbacher

IPC分类号： C13K1/02 ,  C07D307/50 ,  C13K13/00

CPC分类号： C13K1/02 ,  C07D307/46 ,  C07D307/50 ,  C07H3/06 ,  C13K1/06 ,  C13K13/002

摘要： A process to produce an aqueous solution of carbohydrates that contains C6-sugar-containing oligomers, C6 sugar monomers, C5-sugar-containing oligomers, C5 sugar monomers, or any combination thereof is presented. The process includes the steps of reacting biomass or a biomass-derived reactant with a solvent system including a lactone and water, and an acid catalyst. The reaction yields a product mixture containing water-soluble C6-sugar-containing oligomers, C6-sugar monomers, C5-sugar-containing oligomers, C5-sugar monomers, or any combination thereof. A solute is added to the product mixture to cause partitioning of the product mixture into an aqueous layer containing the carbohydrates and a substantially immiscible organic layer containing the lactone.

摘要翻译： 提供了含有含C6-糖的低聚物，C6糖单体，C5-糖低聚物，C5糖单体或其任何组合的碳水化合物水溶液的方法。 该方法包括使生物质或生物质衍生的反应物与包括内酯和水的溶剂体系以及酸催化剂反应的步骤。 该反应产生含有水溶性的含C6糖的低聚物，C6-糖单体，含C5糖的低聚物，C5-糖单体或其任何组合的产物混合物。 将溶质加入到产物混合物中以使产物混合物分配成含有碳水化合物的水层和含有内酯的基本上不混溶的有机层。

公开(公告)号：US20150218118A1

公开(公告)日：2015-08-06

申请号：US14424372

申请日：2013-09-02

申请人： ANNIKKI GMBH

发明人： Marko Mihovilovic ,  Michael Schön ,  Johanna Hölbling

IPC分类号： C07D307/50

CPC分类号： C07D307/50

摘要： A process for the production of furan derivatives from carbohydrates in the presence of an acidic catalyst, characterized in that N-methylpyrrolidone is used as a solvent and that the acidic catalyst is homogeneous.

摘要翻译： 一种在酸性催化剂存在下由碳水化合物生产呋喃衍生物的方法，其特征在于使用N-甲基吡咯烷酮作为溶剂，酸性催化剂是均匀的。

公开(公告)号：US20150166499A1

公开(公告)日：2015-06-18

申请号：US14411720

申请日：2013-07-01

申请人： NANYANG TECHNOLOGICAL UNIVERSITY

发明人： Teck Peng Loh ,  Peng Wang ,  Daniel Hartoyo Lukamto

IPC分类号： C07D307/50

CPC分类号： C07D307/50

摘要： The disclosure provides the use of aryl or heteroaryl boronic acid in the preparation of 5-(hydroxymethyl)fufural (HMF) from saccharides. The aryl or heteroaryl boronic bearing electron-withdrawing groups on the aryl or heteroaryl ring of the boronic acid provided good yields. The disclosure provides a method for preparing HMF from saccharides in the presence of aryl or heteroaryl boronic acid. The disclosure provides a method for converting a saccharide other than fructose in fructose via a dehydrogenation reaction catalyzed by aryl or heteroaryl boronic acid.

摘要翻译： 本公开提供了芳基或杂芳基硼酸在从糖类制备5-（羟甲基）呋喃磺酸（HMF）中的用途。 在硼酸的芳基或杂芳基环上带有芳基或杂芳基硼的吸电子基团提供了良好的收率。 本公开提供了在芳基或杂芳基硼酸存在下从糖制备HMF的方法。 本公开提供了通过由芳基或杂芳基硼酸催化的脱氢反应来转化果糖中的果糖以外的糖的方法。

公开(公告)号：US20150152074A1

公开(公告)日：2015-06-04

申请号：US14619611

申请日：2015-02-11

申请人： E I DU PONT DE NEMOURS AND COMPANY

发明人： DAVID RICHARD CORBIN ,  PAUL JOSEPH FAGAN ,  STUART B. FERGUSSON ,  KEITH W. HUTCHENSON ,  PRANIT S. METKAR ,  RONNIE OZER ,  CARMO JOSEPH PEREIRA ,  BHUMA RAJAGOPALAN ,  SOURAV KUMAR SENGUPTA ,  ERIC J. TILL

IPC分类号： C07D307/50

CPC分类号： C07D307/50 ,  C07D307/48 ,  Y02P20/127

摘要： Furfural is produced by contacting a feedstock solution containing C5 sugar and/or C6 sugar with a solid acid catalyst using reactive distillation. Both high yield and high conversion are obtained, without production of insoluble char in the reaction vessel. Degradation of furfural is minimized by its low residence time in contact with the solid acid catalyst. Higher catalyst lifetime can be achieved because the catalyst is continually washed with the refluxing aqueous solution and not sitting in high-boiling byproducts like humins, which are known to be deleterious to catalyst lifetime.

摘要翻译： 通过使用反应蒸馏将含有C5糖和/或C6糖的原料溶液与固体酸催化剂接触来制备糠醛。 获得高产率和高转化率，而在反应容器中不产生不溶性焦炭。 通过其与固体酸催化剂接触的低停留时间使糠醛的降解最小化。 可以实现更高的催化剂寿命，因为催化剂连续地用回流水溶液洗涤，而不是位于已知对催化剂寿命有害的高沸点副产物如胡氏。

公开(公告)号：US09012664B2

公开(公告)日：2015-04-21

申请号：US13729445

申请日：2012-12-28

申请人： E I du Pont de Nemours and Company

发明人： David Richard Corbin ,  Paul Joseph Fagan ,  Stuart B Fergusson ,  Keith W Hutchenson ,  Pranit S Metkar ,  Ronnie Ozer ,  Carmo Joseph Pereira ,  Bhuma Rajagopalan ,  Sourav Kumar Sengupta ,  Eric J. Till

IPC分类号： C07D307/48 ,  C07D307/50

CPC分类号： C07D307/50 ,  C07D307/48 ,  Y02P20/127

摘要： Furfural is produced by contacting a feedstock solution containing C5 sugar and/or C6 sugar with a solid acid catalyst using reactive distillation. Both high yield and high conversion are obtained, without production of insoluble char in the reaction vessel. Degradation of furfural is minimized by its low residence time in contact with the solid acid catalyst. Higher catalyst lifetime can be achieved because the catalyst is continually washed with the refluxing aqueous solution and not sitting in high-boiling byproducts like humins, which are known to be deleterious to catalyst lifetime.

摘要翻译： 通过使用反应蒸馏将含有C5糖和/或C6糖的原料溶液与固体酸催化剂接触来制备糠醛。 获得高产率和高转化率，而在反应容器中不产生不溶性焦炭。 通过其与固体酸催化剂接触的低停留时间使糠醛的降解最小化。 可以实现更高的催化剂寿命，因为催化剂连续地用回流水溶液洗涤，而不是位于已知对催化剂寿命有害的高沸点副产物如胡氏。

公开(公告)号：US20150031904A1

公开(公告)日：2015-01-29

申请号：US14383439

申请日：2012-07-26

申请人： Korea Institute of Industrial Technology

发明人： Jin Ku Cho ,  Jaewon Jeong ,  Sangyong Kim ,  Bora KIM ,  Baek-Jin Kim ,  Seunghan Shin ,  Dohoon Lee

IPC分类号： C07D307/50

CPC分类号： C07D307/50 ,  B01J31/08 ,  C07D307/48 ,  Y02P20/582

摘要： Provided herein is a method for producing 5-hydroxymethyl-2-furfural (HMF) from maize syrup containing fructose including a conversion step in which a reaction product containing the 5-hydroxymethyl-2-furfural is produced by mixing and heating the maize syrup, a dioxane solvent and a solid acid catalyst, thus providing an advantage that the solvent can be easily isolated and the isolated solvent can be reused because dioxane is used as the solvent, and an advantage that the catalyst can be easily isolated and the isolated catalyst can be easily reused because a nonuniform solid acid catalyst is used.

摘要翻译： 本文提供了含有果糖的玉米糖浆中的5-羟甲基-2-糠醛（HMF）的制备方法，包括转化步骤，其中通过混合和加热玉米糖浆产生含有5-羟甲基-2-糠醛的反应产物， 二恶烷溶剂和固体酸催化剂，从而提供了可以容易地分离溶剂并且由于使用二恶烷作为溶剂可以重复使用分离的溶剂的优点，以及可以容易地分离催化剂并且分离的催化剂可以 由于使用不均匀的固体酸催化剂，容易重复使用。

公开(公告)号：US20140235881A1

公开(公告)日：2014-08-21

申请号：US14348566

申请日：2012-07-09

申请人： Jin Ku Cho ,  Sang Yong Kim ,  Jae Hoon Cho ,  Bo Ra Kim ,  Paul Joo

发明人： Jin Ku Cho ,  Sang Yong Kim ,  Jae Hoon Cho ,  Bo Ra Kim ,  Paul Joo

IPC分类号： C07D307/50

CPC分类号： C07D307/50 ,  C07D307/46 ,  C07D307/48

摘要： The present invention relates to a method for producing a furan-based compound using an ion exchange resin in the presence of an organic solvent. In the method for producing a furan-based compound according to the present invention, a furan-based compound is made from an aldose-type hexose compound in the presence of an organic solvent by using an anion exchange resin and a cation exchange resin. Thus, the aldose-type hexose compound obtained from biomass by simultaneously or consecutively using the anion/cation exchange resins as catalysts can be made into 5-hydroxymethyl-2-furfural (HMF) or alkyl ether derivatives thereof such as 5-alkoxymethyl-2-furfural (AMF) without using an expensive reagent. Also, since the selection of an organic solvent is not limitative and a heterogeneous catalyst can be used, separation and purification is easy and chemically stable AMF can be directly obtained. Further, the conversion efficiency of the aldose-type hexose compound is excellent, and the hexose compound can be used at a high concentration.

摘要翻译： 本发明涉及在有机溶剂存在下使用离子交换树脂生产呋喃类化合物的方法。 在本发明的呋喃类化合物的制造方法中，通过使用阴离子交换树脂和阳离子交换树脂，在有机溶剂的存在下，通过醛糖型己糖化合物制造呋喃系化合物。 因此，通过同时或连续使用阴离子/阳离子交换树脂作为催化剂从生物质获得的醛糖型己糖化合物可以制成5-羟甲基-2-糠醛（HMF）或其烷基醚衍生物，例如5-烷氧基甲基-2 （AMF），而不使用昂贵的试剂。 此外，由于有机溶剂的选择不是限制性的并且可以使用多相催化剂，所以分离和纯化容易，并且可以直接获得化学稳定的AMF。 此外，醛糖型己糖化合物的转化效率优异，可以高浓度使用己糖化合物。

公开(公告)号：US20140227742A1

公开(公告)日：2014-08-14

申请号：US14342634

申请日：2012-09-21

申请人： ARCHER DANIELS MIDLAND COMPANY

发明人： Wuli Bao ,  Thomas Binder ,  Charles Abbas ,  Lucas Loveless

IPC分类号： C12P19/00 ,  D21C3/04

CPC分类号： C12P17/04 ,  C07D307/08 ,  C07D307/36 ,  C07D307/50 ,  C08B1/003 ,  C08B3/00 ,  C08B3/06 ,  C08B37/14 ,  C08H6/00 ,  C08H8/00 ,  C08L1/12 ,  C08L5/14 ,  C08L97/005 ,  C12P7/06 ,  C12P7/10 ,  C12P7/14 ,  C12P19/00 ,  C12P19/02 ,  C12P19/04 ,  C12P19/14 ,  C12P2201/00 ,  C12P2203/00 ,  C12Y301/00 ,  C12Y302/01004 ,  C13K1/02 ,  C13K13/002 ,  D21C3/04 ,  Y02E50/16 ,  Y02E50/17

摘要： A process for production of C5 and C6 sugar enriched syrups from lignocellulosic biomass and fermentation products therefrom is described. A lignocellulosic biomass is treated with a C1-C2 acid (e.g., acetic acid) with washing thereof with a C1-C2 acid miscible organic solvent, (e.g., ethyl acetate). A soluble hemicellulose and lignin enriched fraction is obtained separately from a cellulose pulp enriched fraction and lignin is removed from the soluble hemicellulose fraction. These fractions contain acylated (e.g., acetylated) cellulose and hemicellulose, which are deacylated by treatment with an alkali and/or with an acetyl esterase enzyme. The deacylated fractions are then digested with suitable cellulolytic and/or hemicellulolytic enzymes, preferably in the presence of non-ionic detergent to yield the C5 and C6 enriched syrups. Also described are method of fermentation of the syrups to make ethanol to at least 7% w/vol by separate hydrolysis and fermentation (SHF) or simultaneous hydrolysis and fermentation (SSF) methods.

公开(公告)号：US08795393B2

公开(公告)日：2014-08-05

申请号：US13320058

申请日：2010-04-15

申请人： Jin-Ku Cho ,  Sang-Yong Kim ,  Do-Hoon Lee ,  Bo-Ra Kim ,  Jae-Won Jung

发明人： Jin-Ku Cho ,  Sang-Yong Kim ,  Do-Hoon Lee ,  Bo-Ra Kim ,  Jae-Won Jung

IPC分类号： C10L1/18 ,  C07C69/66 ,  C07D307/50

CPC分类号： C07D233/24 ,  C07D307/48 ,  C07D307/50 ,  C10G2300/1014 ,  C10G2300/44 ,  C10L1/02 ,  C10L1/026 ,  Y02E50/13 ,  Y02P30/20

摘要： Disclosed is a method of preparing a petroleum-alternative bio fuel material such as 5-hydroxymethyl-2-furfural (HMF), 5-alkoxymethyl-2-furfural, levulinic acid alkil ester, etc. through a single process without saccharification, using a catalyst conversion reaction, from galactan that can be massively supplied at low costs and extracted from macroalgae of marine reusable resources.Thus, the macroalgae of the marine biomass resources is used so that a carbon source can be more easily extracted than that of a lignocellulosic biomass resource without a problem of having an effect on grain price like a crop-based biomass.

摘要翻译： 公开了一种通过没有糖化的单一方法制备石油替代生物燃料材料如5-羟甲基-2-糠醛（HMF），5-烷氧基甲基-2-糠醛，乙酰丙酸烷基酯等的方法，使用 催化剂转化反应，可以以低成本大量供应并从海洋可再利用资源的大型藻类中提取的半乳聚糖。 因此，使用海洋生物质资源的大型藻类，使得碳源比木质纤维素生物质资源更容易提取，而不会对谷物价格产生影响，如作物生物量。