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118 条记录 (耗时 0.034 秒)

    Composition for preventing or treating autoimmune disease, comprising, as active ingredient, PINK1 protein or polynucleotide encoding same
    5.
    发明授权
    Composition for preventing or treating autoimmune disease, comprising, as active ingredient, PINK1 protein or polynucleotide encoding same 有权
    用于预防或治疗自身免疫性疾病的组合物，其包含PINK1蛋白或编码其的多核苷酸作为活性成分

    公开(公告)号：US09585945B2

    公开(公告)日：2017-03-07

    申请号：US14948095

    申请日：2015-11-20

    申请人： CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

    发明人： Mi-La Cho ,  Hyang-Suk Rhim ,  Seon-Yeong Lee ,  Yeong-Mi Mun ,  Hye-Jin Son ,  Eun-Ji Yang ,  Eun-Kyung Kim

    IPC分类号： C12N9/12 ,  A61K48/00 ,  A61K38/45

    CPC分类号： A61K38/45 ,  A61K48/005 ,  C12N9/12 ,  C12Y207/11001

    摘要： The present invention relates to a composition for preventing or treating an autoimmune disease comprising, as an active ingredient, PINK1 protein or polynucleotide encoding the same. The PINK1 protein according to the present invention inhibits the activity of Th17, promotes the activity of a regulatory T cell (Treg), and increases autophagy in Treg cells, thereby controlling excessive immune responses. Therefore, the PINK1 protein can be effectively used as a pharmaceutical composition or an immunosuppressant, which is capable of preventing or treating an autoimmune disease, such as arthritis, and the like, caused by dysregulation of various kinds of immune responses.

    摘要翻译： 本发明涉及用于预防或治疗自身免疫疾病的组合物，其包含作为活性成分的PINK1蛋白或编码该组合物的多核苷酸。 根据本发明的PINK1蛋白抑制Th17的活性，促进调节性T细胞（Treg）的活性，并增加Treg细胞中的自噬，由此控制过度的免疫应答。 因此，可以将PINK1蛋白质有效地用作药物组合物或免疫抑制剂，其能够预防或治疗由各种免疫反应失调引起的自身免疫疾病如关节炎等。

    APPARATUS AND METHOD FOR MEASURING THERMAL CONDUCTIVITY IN BURNS
    7.
    发明申请
    APPARATUS AND METHOD FOR MEASURING THERMAL CONDUCTIVITY IN BURNS 有权
    用于测量BURNS中热导率的装置和方法

    公开(公告)号：US20160256099A1

    公开(公告)日：2016-09-08

    申请号：US14426715

    申请日：2014-12-24

    申请人： CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

    发明人： Jun Yong Lee

    IPC分类号： A61B5/00 ,  G01N25/18

    CPC分类号： A61B5/445 ,  G01K11/12 ,  G01N25/18

    摘要： There are provided an apparatus and method for measuring thermal conductivity capable of easily and accurately obtaining an extent of thermal damage of a targeted tissue. The apparatus for measuring thermal conductivity in burns includes a thermal paper stacking member having a plurality of sheets of thermal paper stacked thereon to form layers, and a pressing member configured to press the stacking member so that the thermal paper is stacked and maintained in a closely adhered state. Here, an extent of thermal damage of the targeted tissue according to the depth can be calculated as an extent of thermal damage of the stacking member according to the depth.

    摘要翻译： 提供了一种用于测量导热性的装置和方法，其能够容易且准确地获得目标组织的热损伤程度。 用于测量灼伤热导率的装置包括：热敏纸堆叠构件，其具有堆叠在其上的多个热敏纸层以形成层;以及按压构件，其构造成按压堆叠构件，使得热敏纸层叠并保持紧密 粘附状态 这里，可以根据深度来计算目标组织的热损伤程度，作为堆积部件的热损伤程度。

    Diagnosis kit for rheumatoid arthritis
    8.
    发明授权
    Diagnosis kit for rheumatoid arthritis 有权
    类风湿关节炎诊断试剂盒

    公开(公告)号：US09347941B2

    公开(公告)日：2016-05-24

    申请号：US14371792

    申请日：2012-10-31

    申请人： CATHOLIC UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION

    发明人： Ji-Hyeon Ju ,  Young-Kyun Kim

    IPC分类号： G01N33/00 ,  G01N33/564

    CPC分类号： G01N33/564 ,  G01N2800/102

    摘要： A method for diagnosing rheumatoid arthritis, based on the detection of citrullinated autoantigens in a test sample is disclosed. The method diagnoses rheumatoid arthritis more accurately and rapidly. Also disclosed is a kit for carrying out the method.

    摘要翻译： 公开了一种基于检测样品中瓜氨酸化自身抗原的方法来诊断类风湿性关节炎。 该方法更准确，快速地诊断类风湿关节炎。 还公开了用于实施该方法的工具包。

    Dental RF coil, head-fixing unit, and magnetic resonance imaging system including same
    10.
    发明授权
    Dental RF coil, head-fixing unit, and magnetic resonance imaging system including same 有权
    牙科RF线圈，头部固定单元和包括它们的磁共振成像系统

    公开(公告)号：US09226685B2

    公开(公告)日：2016-01-05

    申请号：US13522686

    申请日：2010-08-31

    申请人： Bo Young Choe ,  Dong Cheol Woo ,  Hyun Sub Ahn

    发明人： Bo Young Choe ,  Dong Cheol Woo ,  Hyun Sub Ahn

    IPC分类号： A61B5/055 ,  A61B5/00 ,  G01R33/34 ,  G01R33/341 ,  G01R33/38

    CPC分类号： A61B5/0555 ,  A61B5/4542 ,  A61B5/4547 ,  A61B5/682 ,  G01R33/34084 ,  G01R33/341 ,  G01R33/3806

    摘要： The invention relates to an MRI system, comprising: an examination table including a cradle in which a patient may be positioned; a magnetic assembly disposed in the examination table and including first and second electrode assemblies, the respective electrode surfaces of which are disposed so as to be perpendicularly spaced apart by a certain distance and opposite each other such that space for imaging may be formed therebetween; and an RF coil unit contactingly or contactlessly attached to a part of a patient to be examined or an attached part corresponding to the part to be examined, applying an RF pulse to the part of the patient to be examined, and detecting an MR signal from the examined part.

    摘要翻译： 本发明涉及一种MRI系统，包括：检查台，其包括可在其中定位患者的支架; 磁性组件，设置在检查台中，并且包括第一和第二电极组件，其各自的电极表面设置成垂直间隔开一定距离并且彼此相对，使得可以在其间形成用于成像的空间; 以及射频线圈单元，其接触或非接触地附接到要检查的患者的一部分或对应于待检查部分的附接部分，将RF脉冲施加到待检查的患者部分，并且检测来自 被检查部分。