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16 条记录 (耗时 0.017 秒)

    Rapid-Melt Compositions and Methods of Making Same
    5.
    发明申请
    Rapid-Melt Compositions and Methods of Making Same 审中-公开
    快速熔体组合物及其制备方法

    公开(公告)号：US20100010101A1

    公开(公告)日：2010-01-14

    申请号：US12501652

    申请日：2009-07-13

    申请人： S. Rao Cherukuri

    发明人： S. Rao Cherukuri

    IPC分类号： A61K47/04 ,  A61K47/12

    CPC分类号： A61K9/0056 ,  A61K9/1617 ,  A61K9/1641 ,  A61K9/1664 ,  A61K9/1694 ,  A61K9/2013 ,  A61K9/2031 ,  A61K9/2068 ,  A61K9/2095 ,  A61K31/09 ,  A61K31/137 ,  A61K31/351 ,  A61K31/375 ,  A61K31/60 ,  A61K31/726

    摘要： The present invention provides a novel rapid-melt pharmaceutical composition comprising a binder, a super emulsifier, a diluent/bulking material; and an active ingredient. The present invention also provides a rapid-melt bead composition comprising a binder having a melting point from about 20 to about 90° C., an emulsifier; a diluent/bulking material; and an active ingredient. Further, the present invention provides a chew tablet composition comprising a binder; an emulsifier having a melting point of greater than about 40° C.; a diluent/bulking material; and an active ingredient. Methods of making the disclosed compositions are also described.

    摘要翻译： 本发明提供一种新型的快速熔融药物组合物，其包含粘合剂，超级乳化剂，稀释剂/填充材料; 和活性成分。 本发明还提供一种包含熔点约20-90℃的粘合剂的快速熔融珠组合物，一种乳化剂; 稀释剂/膨胀材料; 和活性成分。 此外，本发明提供一种包含粘合剂的咀嚼片组合物; 具有大于约40℃的熔点的乳化剂; 稀释剂/膨胀材料; 和活性成分。 还描述了制备所公开的组合物的方法。

    Orally disintegrating layered compositions
    9.
    发明申请
    Orally disintegrating layered compositions 失效
    口腔崩解分层组合物

    公开(公告)号：US20080014268A1

    公开(公告)日：2008-01-17

    申请号：US11819326

    申请日：2007-06-26

    申请人： Subraman Cherukuri

    发明人： Subraman Cherukuri

    IPC分类号： A61K9/24 ,  A61K9/00 ,  A61K9/28 ,  A61K9/22

    CPC分类号： A61K9/2086 ,  A61K9/0056

    摘要： The present invention is directed to multi-layered compositions for oral administration having at least one orally disintegrating layer and capable of maintaining layer cohesion. The present invention is also directed to methods of manufacturing such compositions.

    摘要翻译： 本发明涉及具有至少一个口腔崩解层并能够保持层内聚力的口服多层组合物。 本发明还涉及制造这种组合物的方法。

    Chewy products and methods for making the same
    10.
    发明申请
    Chewy products and methods for making the same 审中-公开
    耐嚼产品和方法制作相同

    公开(公告)号：US20080008742A1

    公开(公告)日：2008-01-10

    申请号：US11819902

    申请日：2007-06-29

    申请人： Subraman Cherukuri

    发明人： Subraman Cherukuri

    IPC分类号： A61K47/00 ,  A61K9/20

    CPC分类号： A61K9/0056 ,  A61K9/0058

    摘要： Methods for producing chewable emulsion compositions and compositions produced from such methods are disclosed. The emulsion base may be prepared by contacting an aqueous phase and a nonaqueous phase in the presence of an emulsifier. The aqueous phase is prepared under conditions that permit no substantial moisture loss and reduced viscosity. The methods permit preparing chewable compositions for delivering confectionary items, nutriceuticals, vitamins, minerals and therapeutically active agents. The compositions may be sugar-free or sugar-containing. The active agent may be added to the emulsion base at a lower temperature compared to the temperature at which either the aqueous or nonaqueous phase is formed. The compositions may be further coated with taste-masking materials, enteric coating materials, or slow-release materials. The compositions may be formed into compressible tablets, beads, granules, or otherwise generally known dosage forms.

    摘要翻译： 公开了生产可咀嚼乳液组合物的方法和由这些方法制备的组合物。 乳液基质可以通过在乳化剂存在下使水相和非水相接触来制备。 水相在不允许大量水分损失和降低粘度的条件下制备。 该方法允许制备用于递送糖果物品，营养物质，维生素，矿物质和治疗活性剂的咀嚼组合物。 组合物可以是无糖或含糖的。 与形成水相或非水相的温度相比，活性剂可以在较低温度下加入到乳液基质中。 组合物可以进一步用味道掩蔽材料，肠溶衣材料或缓释材料涂覆。 组合物可形成可压片，珠粒，颗粒或其他通常已知的剂型。