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    Percutaneous temporary aortic valve
    1.
    发明授权
    Percutaneous temporary aortic valve 有权

    公开(公告)号：US11826253B2

    公开(公告)日：2023-11-28

    申请号：US16934853

    申请日：2020-07-21

    申请人： HOCOR Cardiovascular Technologies LLC

    发明人： Paul C. Ho

    IPC分类号： A61F2/24

    CPC分类号： A61F2/246 ,  A61F2/2412 ,  A61F2/2427 ,  A61F2/2454 ,  A61F2/2466 ,  A61F2230/0008 ,  A61F2230/0067 ,  A61F2250/0059

    摘要： Methods and apparatuses for regulating aortic regurgitation are provided. A catheter shaft is advanced through vasculature so that a flexible occluding membrane coupled to the catheter shaft is positioned within the aorta, typically the ascending aorta above the Sinus of Valsalva and coronary ostia. Blood flow in the aorta causes the flexible occluding membrane to alternate between an expanded occluding configuration while in diastole and a collapsed lesser occluding configuration is systole. The flexible occluding membrane thereby acts as a temporary aortic valve. The flexible occluding membrane is generally conical in shape, with the tip of the cone disposed closer to the aorta than the proximal rim. In diastole, blood flow expands the flexible occluding membrane so that the proximal rim apposes the inner wall of the aorta. The flexible occluding membrane will have one or more openings to allow perfusion of the coronary arteries in diastole.

    PERCUTANEUOUS TEMPORARY AORTIC VALVE
    2.
    发明申请
    PERCUTANEUOUS TEMPORARY AORTIC VALVE 有权

    公开(公告)号：US20210169641A1

    公开(公告)日：2021-06-10

    申请号：US16934853

    申请日：2020-07-21

    申请人： HOCOR Cardiovascular Technologies LLC

    发明人： Paul C. HO

    IPC分类号： A61F2/24

    摘要： Methods and apparatuses for regulating aortic regurgitation are provided. A catheter shaft is advanced through vasculature so that a flexible occluding membrane coupled to the catheter shaft is positioned within the aorta, typically the ascending aorta above the Sinus of Valsalva and coronary ostia. Blood flow in the aorta causes the flexible occluding membrane to alternate between an expanded occluding configuration while in diastole and a collapsed lesser occluding configuration is systole. The flexible occluding membrane thereby acts as a temporary aortic valve. The flexible occluding membrane is generally conical in shape, with the tip of the cone disposed closer to the aorta than the proximal rim. In diastole, blood flow expands the flexible occluding membrane so that the proximal rim apposes the inner wall of the aorta. The flexible occluding membrane will have one or more openings to allow perfusion of the coronary arteries in diastole.

    Method and system for balloon counterpulsation during aortic valve replacement
    3.
    发明授权
    Method and system for balloon counterpulsation during aortic valve replacement 有权

    公开(公告)号：US10881412B2

    公开(公告)日：2021-01-05

    申请号：US16129719

    申请日：2018-09-12

    申请人： HOCOR Cardiovascular Technologies LLC

    发明人： Paul C. Ho

    IPC分类号： A61B17/12 ,  A61F2/24 ,  A61M25/10 ,  A61B17/00

    摘要： Methods and systems for regulating aortic regurgitation during aortic valve replacement or repair procedures utilize a temporary aortic valve (TAV) catheter and a controller. The temporary aortic valve catheter has an expandable occlusion device which can partially occlude the aortic lumen during ventricular diastole with a lesser occlusion during ventricular systole. Exemplary balloon structures include multiple, independently inflatable balloons which are inflated in synchrony with the cardiac cycle by the controller. By controlling aortic regurgitation, the repair or replacement protocols can be conducted with less interference from blood flow.

    Method and apparatus for percutaneous aortic valve replacement
    4.
    发明授权
    Method and apparatus for percutaneous aortic valve replacement 有权
    用于经皮主动脉瓣置换术的方法和装置

    公开(公告)号：US08663318B2

    公开(公告)日：2014-03-04

    申请号：US11781924

    申请日：2007-07-23

    申请人： Paul C. Ho

    发明人： Paul C. Ho

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2433 ,  A61B17/12022 ,  A61B17/1204 ,  A61B17/12136 ,  A61B2017/22055 ,  A61B2017/22067 ,  A61F2/2418 ,  A61F2250/0059

    摘要： A catheter adapted for placement in the ascending aorta comprises a central catheter mechanism and a balloon structure or other occluding structure at its distal end. The catheter may be placed over the aortic arch such that the balloon structure is placed in the ascending aorta just above the Sinus of Valsalva and coronary ostia. Once in place, the balloon structure is inflated to control blood flow through the aorta during aortic valve ablation and replacement protocols.

    摘要翻译： 适于放置在升主动脉中的导管在其远端包括中心导管机构和球囊结构或其它阻塞结构。 导管可以放置在主动脉弓上，使得球囊结构置于正好位于Valsalva窦和冠状动脉口上方的升主动脉。 一旦到位，气囊结构被充气以在主动脉瓣消融和置换方案期间控制通过主动脉的血流。

    METHOD AND SYSTEM FOR BALLOON COUNTERPULSATION DURING AORTIC VALVE REPLACEMENT
    5.
    发明申请
    METHOD AND SYSTEM FOR BALLOON COUNTERPULSATION DURING AORTIC VALVE REPLACEMENT 有权
    用于气动阀门替换期间的气球计数的方法和系统

    公开(公告)号：US20120116439A1

    公开(公告)日：2012-05-10

    申请号：US13227276

    申请日：2011-09-07

    申请人： Paul C. Ho

    发明人： Paul C. Ho

    IPC分类号： A61M29/00

    CPC分类号： A61B17/12136 ,  A61B17/1204 ,  A61B17/12118 ,  A61B2017/00703 ,  A61F2/2427 ,  A61F2250/0059 ,  A61M25/1011

    摘要： Methods and systems for regulating aortic regurgitation during aortic valve replacement or repair procedures utilize a temporary aortic valve (TAV) catheter and a controller. The temporary aortic valve catheter has an expandable occlusion device which can partially occlude the aortic lumen during ventricular diastole with a lesser occlusion during ventricular systole. Exemplary balloon structures include multiple, independently inflatable balloons which are inflated in synchrony with the cardiac cycle by the controller. By controlling aortic regurgitation, the repair or replacement protocols can be conducted with less interference from blood flow.

    摘要翻译： 用于调节主动脉瓣置换或修复过程中主动脉瓣反流的方法和系统使用临时主动脉瓣（TAV）导管和控制器。 临时主动脉瓣导管具有可扩张的闭塞装置，其可以在心室舒张期期间部分闭塞主动脉腔，在心室收缩期间具有较小的闭塞。 示例性球囊结构包括由控制器与心动周期同步地充气的多个独立可充气球囊。 通过控制主动脉瓣反流，可以以较少的血流干扰进行修复或替换方案。

    Means and method of replacing a heart valve in a minimally invasive manner
    7.
    再颁专利
    Means and method of replacing a heart valve in a minimally invasive manner 有权
    以微创方式更换心脏瓣膜的方法和方法

    公开(公告)号：USRE40377E1

    公开(公告)日：2008-06-10

    申请号：US10863862

    申请日：2004-06-07

    申请人： Warren P. Williamson, IV ,  Paul A. Spence ,  George T. Christakis ,  Mark Ortiz

    发明人： Warren P. Williamson, IV ,  Paul A. Spence ,  George T. Christakis ,  Mark Ortiz

    IPC分类号： A61F2/24

    摘要： A heart valve can be replaced using minimally invasive methods which include a sutureless sewing cuff that and a fastener delivery tool that holds the cuff against the patient's tissue while delivering fasteners to attach the cuff to the tissue from the inside out. The tool stores a plurality of fasteners and is self-contained whereby a fastener is delivered and placed all from inside a vessel. The fasteners are self-forming whereby they do not need an anvil to be formed. Anchor elements are operated from outside the patient's body to cinch a prosthesis to an anchoring cuff of the valve body. The cuff is releasably mounted on the tool and the tool holds the cuff against tissue and drives the fastener through the cuff and the tissue before folding over the legs of the fastener whereby secure securement between the cuff and the tissue is assured. Fasteners are placed and formed whereby fasteners are located continuously throughout the entire circumference of the cuff. A minimally invasive surgical method is disclosed, and a method and tool are disclosed for repairing abdominal aortic aneurysms in a minimally invasive manner. Fasteners that are permanently deformed during the process of attaching the cuff are disclosed as are fasteners that are not permanently deformed during the attaching process.

    摘要翻译： 可以使用微创方法来替换心脏瓣膜，所述方法包括无缝线缝合套，以及紧固件递送工具，其将袖带保持抵靠患者组织，同时递送紧固件以将袖带从内向外附接到组织。 该工具存储多个紧固件并且是独立的，由此紧固件全部从容器内部输送和放置。 紧固件是自成型的，由此它们不需要形成砧座。 锚杆元件从患者身体外部操作，将假体固定到阀体的锚定箍。 袖带可释放地安装在工具上，并且工具将袖带保持抵靠组织，并且在折叠紧固件的腿部之前通过袖口和组织驱动紧固件，从而确保袖带和组织之间的牢固固定。 紧固件被放置和形成，由此紧固件连续地位于袖带的整个圆周上。 公开了一种微创手术方法，并且公开了一种以微创方式修复腹主动脉瘤的方法和工具。 在附接袖带的过程中永久变形的紧固件公开为在附接过程中不会永久变形的紧固件。

    Methods and apparatus for percutaneous aortic valve replacement
    8.
    发明授权
    Methods and apparatus for percutaneous aortic valve replacement 有权

    公开(公告)号：US10080654B2

    公开(公告)日：2018-09-25

    申请号：US15277807

    申请日：2016-09-27

    申请人： HOCOR Cardiovascular Technologies, LLC

    发明人： Paul C. Ho

    IPC分类号： A61F2/24 ,  A61B17/12 ,  A61B17/00

    CPC分类号： A61F2/2418 ,  A61B17/12036 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12122 ,  A61B17/12136 ,  A61B2017/00703 ,  A61F2/2433 ,  A61F2250/0059 ,  A61F2250/006

    摘要： A delivery system and method for percutaneous aortic valve (PAV) replacement and apparatus used therein. A temporary aortic valve including a reversibly expandable occluding medium surrounds a central catheter mechanism. The temporary valve is positioned within the ascending aorta, just above and downstream from the coronary ostia. The occluding medium is configured such that, when fully expanded against the aortic wall, gaps are left that promote continuous coronary perfusion during the cardiac cycle. The temporary valve substitutes for the function of the native aortic valve during its replacement. The native aortic valve is next dilated, and then ablated through deployment of low profile, elongated, sequentially delivered stents. The stent(s) displace the native tissues and remain within the aortic annulus to receive and provide a structure for retaining the PAV. The PAV is delivered, positioned and deployed within the stent(s) at the aortic annulus with precision and relative ease.

    Method and system for balloon counterpulsation during aortic valve replacement
    10.
    发明授权
    Method and system for balloon counterpulsation during aortic valve replacement 有权

    公开(公告)号：US10098644B2

    公开(公告)日：2018-10-16

    申请号：US15058999

    申请日：2016-03-02

    申请人： HOCOR Cardiovascular Technologies LLC

    发明人： Paul C. Ho

    IPC分类号： A61M29/00 ,  A61B17/12 ,  A61F2/24 ,  A61B17/00 ,  A61M25/10

    摘要： Methods and systems for regulating aortic regurgitation during aortic valve replacement or repair procedures utilize a temporary aortic valve (TAV) catheter and a controller. The temporary aortic valve catheter has an expandable occlusion device which can partially occlude the aortic lumen during ventricular diastole with a lesser occlusion during ventricular systole. Exemplary balloon structures include multiple, independently inflatable balloons which are inflated in synchrony with the cardiac cycle by the controller. By controlling aortic regurgitation, the repair or replacement protocols can be conducted with less interference from blood flow.