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    ADVANTAGEOUS SALTS OF MU-OPIATE RECEPTOR PEPTIDES
    3.
    发明申请
    ADVANTAGEOUS SALTS OF MU-OPIATE RECEPTOR PEPTIDES 有权
    多功能受体肽的优势

    公开(公告)号：US20140142050A1

    公开(公告)日：2014-05-22

    申请号：US14056496

    申请日：2013-10-17

    申请人： CYTOGEL PHARMA, LLC

    发明人： THEODORE E MAIONE

    IPC分类号： C07K5/10

    CPC分类号： C07K5/1016 ,  A61K38/00 ,  C07K5/10

    摘要： The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their crystal structure, stability, solubility, lack of impurities and/or the ability to be produced, with these advantageous properties, in amounts sufficient for the production of therapeutic compositions.

    摘要翻译： 本发明提供了有利的mu-阿片受体肽的新盐。 已经发现，这些盐在它们的晶体结构，稳定性，溶解性，缺乏杂质和/或生产能力方面具有优异的性能，具有这些有利的性质，其用量足以制备治疗组合物。

    Injectable microspheres
    4.
    发明授权
    Injectable microspheres 有权
    可注射微球

    公开(公告)号：US08092835B1

    公开(公告)日：2012-01-10

    申请号：US13269738

    申请日：2011-10-10

    申请人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    发明人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    IPC分类号： A61K9/14

    CPC分类号： A61K9/0019 ,  A61K9/1647 ,  Y10T428/2982

    摘要： Injectable microspheres are obtained from double bond functionalized polyhydric alcohol ester by a method comprising dissolving the double bond functionalized esters in a hydrophobic organic solvent, forming an aqueous solution of stabilizer, forming an oil in water emulsion where the solution of stabilizer constitutes the continuous phase and the solution of ester constitutes the disperse phase and evaporating the organic solvent or from block copolymer of PGCLM and methoxy poly(ethylene glycol).

    摘要翻译： 可注射的微球体是通过将双键官能化的酯溶解在疏水性有机溶剂中，形成稳定剂的水溶液，形成稳定剂溶液形成连续相的水乳液的方法从双键官能化的多元醇酯得到的， 酯溶液构成分散相并蒸发有机溶剂或由PGCLM和甲氧基聚（乙二醇）的嵌段共聚物蒸发。

    Injectable microspheres
    8.
    发明授权
    Injectable microspheres 有权
    可注射微球

    公开(公告)号：US08034383B2

    公开(公告)日：2011-10-11

    申请号：US13015193

    申请日：2011-01-27

    申请人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    发明人： Daqing Wu ,  Chih-Chang Chu ,  Joseph Carozza

    IPC分类号： A61K9/14

    CPC分类号： A61K9/0019 ,  A61K9/1647 ,  Y10T428/2982

    摘要： Injectable microspheres are obtained from double bond functionalized polyhydric alcohol ester by a method comprising dissolving the double bond functionalized esters in a hydrophobic organic solvent, forming an aqueous solution of stabilizer, forming an oil in water emulsion where the solution of stabilizer constitutes the continuous phase and the solution of ester constitutes the disperse phase and evaporating the organic solvent or from block copolymer of PGCLM and methoxy poly(ethylene glycol).

    摘要翻译： 可注射的微球体是通过将双键官能化的酯溶解在疏水性有机溶剂中，形成稳定剂的水溶液，形成稳定剂溶液形成连续相的水乳液的方法从双键官能化的多元醇酯得到的， 酯溶液构成分散相并蒸发有机溶剂或由PGCLM和甲氧基聚（乙二醇）的嵌段共聚物蒸发。

    ADVANTAGEOUS SALTS OF MU-OPIATE RECEPTOR PEPTIDES
    10.
    发明申请
    ADVANTAGEOUS SALTS OF MU-OPIATE RECEPTOR PEPTIDES 有权

    公开(公告)号：US20220324908A1

    公开(公告)日：2022-10-13

    申请号：US17554421

    申请日：2021-12-17

    申请人： Cytogel Pharma, LLC

    发明人： Theodore E. MAIONE

    IPC分类号： C07K5/107 ,  C07K5/10

    摘要： The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their crystal structure, stability, solubility, lack of impurities and/or the ability to be produced, with these advantageous properties, in amounts sufficient for the production of therapeutic compositions.