公开(公告)号：US5693606A

公开(公告)日：1997-12-02

申请号：US392044

申请日：1995-02-22

申请人： Ernst Joachim Brunke ,  Dietmar Schatkowski

发明人： Ernst Joachim Brunke ,  Dietmar Schatkowski

IPC分类号： C07C43/303 ,  C11B9/00 ,  A61K7/46

CPC分类号： C07C43/303 ,  C11B9/0042 ,  C07C2103/95

摘要： The described compounds of the general formula A, in which the wavy lines mean .alpha. and .beta. configuration and R.sub.1 and R.sub.2 mean hydrogen, methyl or ethyl groups ##STR1## are new and useful as odorants or components or mixtures of odorants or perfume oils. Their production in a method known per se, involves oxidation of isolongifolene obtained from longifolene to isolongifolane, which is then equilibrated with base extraction and/or reduced to isolongifolan-3-ol and this is then reacted with a symmetric acetal of the formula R.sub.2 --OCHR.sub.1 --O--R.sub.2, in which R.sub.1 is hydrogen or methyl and R.sub.2 is methyl, ethyl or propyl.

摘要翻译： 所描述的通式A的化合物，其中波浪线表示α和β构型，R 1和R 2表示氢，甲基或乙基，作为气味剂或组分或气味剂或香料油的混合物是新的和有用的。 它们以本身已知的方法生产涉及将从长叶菊烯获得的异龙蕊酚氧化成异岐ol烷，然后将其与碱性提取和/或还原成异链球菌-3-醇平衡，然后将其与式R 2 - OCHR1-O-R2，其中R1是氢或甲基，R2是甲基，乙基或丙基。

公开(公告)号：US6045823A

公开(公告)日：2000-04-04

申请号：US120269

申请日：1998-07-22

申请人： Jurgen Vollhardt ,  Robert P. Manzo ,  Nisha Malkan

发明人： Jurgen Vollhardt ,  Robert P. Manzo ,  Nisha Malkan

IPC分类号： A61K8/04 ,  A61K8/14 ,  A61K8/34 ,  A61K8/73 ,  A61K9/127 ,  A61K9/133 ,  A61Q1/06 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q17/00 ,  A61Q19/00 ,  A61K91/127 ,  A61K7/00 ,  A61K7/027 ,  A61K7/32

CPC分类号： A61Q17/005 ,  A61K8/046 ,  A61K8/14 ,  A61K8/34 ,  A61K8/732 ,  A61K9/127 ,  A61Q1/06 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q19/00 ,  Y10S977/907 ,  Y10S977/926

摘要： Anhydrous cosmetic stick formulations such as lip balms, lipsticks, and underarm deodorant or antiperspirant sticks, comprising an organic matrix having particles homogeneously dispersed therein, which particles are preferably prepared by a process comprising spray-drying a mixture of liposome encapsulated active agent, modified starch, and optionally a hydrocolloid gum such as maltodextrin.

摘要翻译： 无水化妆棒配方如唇膏，唇膏，腋下除臭剂或止汗棒，包含均匀分散有颗粒的有机基质，该颗粒优选通过包括喷雾干燥脂质体包封的活性剂，改性淀粉 ，和任选的水胶体胶如麦芽糖糊精。

公开(公告)号：US6152379A

公开(公告)日：2000-11-28

申请号：US307224

申请日：1999-05-07

申请人： Dirk Sorgenfrey

发明人： Dirk Sorgenfrey

IPC分类号： A61L9/01 ,  A61L9/04 ,  A61L9/12

CPC分类号： A61L9/12 ,  A61L9/01 ,  A61L9/04

摘要： Two associated air treatment compositions are formulated such that when used together they produce a constant emanating composition throughout the life of an air treatment dispenser of the wick type (dispenser). Composition I comprises components (at least two active agents) in their respective intended concentrations and is used to impregnate the evaporation surface and/or wick of the dispenser. Composition II comprises the same components (at least the same two active agents) as the first composition. However, the concentrations of the components in Composition II with respect to Composition I are adjusted such that a constant emanating composition is maintained. The relationship between Composition I and II can be described by equation ##EQU1## where ##EQU2## is composition II and ##EQU3## is composition I. Coefficients c.sub.i can be calculated based on quantitative analysis of composition I and II by means known in the art. Composition II serves as a replenishing fluid, typically provided in a reservoir, with which the wick is in contact.

摘要翻译： 两种相关联的空气处理组合物被配制成使得当它们一起使用时，它们在芯型（分配器）的空气处理分配器的整个寿命期间产生恒定的发散组合物。 组合物I包含各自预期浓度的组分（至少两种活性剂），并用于浸渍分配器的蒸发表面和/或油芯。 组合物II包含与第一组合物相同的组分（至少相同的两种活性剂）。 然而，组合物II中组分II相对于组合物I的浓度被调节，使得维持恒定的发散组合物。 组合物I和II之间的关系可以通过其中组成II和组成I的方程式来描述。系数ci可以基于本领域已知方法的组合物I和II的定量分析来计算。 组合物II用作补充流体，通常设置在储存器中，芯与其接触。

公开(公告)号：US5892062A

公开(公告)日：1999-04-06

申请号：US019249

申请日：1998-02-05

申请人： Wilhelm Pickenhagen ,  Dietmar Schatkowski

发明人： Wilhelm Pickenhagen ,  Dietmar Schatkowski

IPC分类号： A61K8/49 ,  A61Q13/00 ,  C07B61/00 ,  C07D317/70 ,  C11B9/00 ,  A61K7/46

CPC分类号： C07D317/70 ,  C11B9/0076

摘要： Cyclic cedrene acetals of the general formula A are described, in which the wavy lines represent the .alpha.- and .beta.-configurations, and R and R.sub.1 are the radicals below: ##STR1## R=R.sub.1 =H R=H, R.sub.1 =Me/R=Me, R.sub.1 =HR=H, R.sub.1 =Et/R=Et, R.sub.1 =HR=H, R.sub.1 =Pr/R=Pr, R.sub.1 =HR=H, R.sub.1 =Bu/R=Bu, R.sub.1 =HR=H, R.sub.1 =Iso-Bu/R=Iso-Bu, R.sub.1 =HR=H, R.sub.1 =Pentyl/R=Pentyl, R.sub.1 =HR=H, R.sub.1 =Iso-Pentyl/R=Iso-Pentyl, R.sub.1 =HR=H, R.sub.1 =Hexyl/R=Hexyl, R.sub.1 =HR=R.sub.1 =Me (.alpha.,.beta.)R=Me, R.sub.1 =Fl/R=Et, R.sub.1 =MeR=R.sub.1 =Fl (.alpha.,.beta.)R=Me, R.sub.1 =Pr/R=Pr, R.sub.1 =MeR=Pt, R.sub.1 =Pr/R=Pr, R=EtR=R.sub.1 =CyclobutylR=R.sub.1 =CyclopentylR=R.sub.1 =Cyclohexyl.

摘要翻译： 描述了通式A的环状雪松缩醛，其中波浪线代表α和β构型，R和R 1是下面的基团：（A）R = R 1 = HR = H，R 1 = Me / R = Me，R1 = HR = H，R1 = Et / R = Et，R1 = HR = H，R1 = Pr / R = Pr，R1 = HR = H，R1 = Bu / R = HR = H，R1 = Iso-Bu / R = Iso-Bu，R1 = HR = H，R1 =戊基/ R =戊基，R1 = HR = H，R1 =异戊基/ R =异戊基，R1 = HR = H，R1 =己基/ R =己基R1 = HR = R1 = Me（α，β）R = Me，R1 = F1 / R = Et，R1 = Me R = R1 = F1（α，β）R = Me，R1 = Pr / R = Pr，R1 = Me R = Pt，R1 = Pr / R = Pr，R = Et R = R1 =环丁基R = R1 =环戊基R = R1 =环己基。

公开(公告)号：US6106849A

公开(公告)日：2000-08-22

申请号：US10246

申请日：1998-01-21

申请人： Nisha Malkan ,  Gary Friars ,  Robert P. Manzo

发明人： Nisha Malkan ,  Gary Friars ,  Robert P. Manzo

IPC分类号： A61K8/73 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q9/02 ,  A61Q17/04 ,  A61Q19/10 ,  C11D3/22 ,  C11D17/00 ,  A61K9/10 ,  A61K47/36

CPC分类号： C11D3/0094 ,  A61K8/73 ,  A61Q17/04 ,  A61Q19/10 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q9/02 ,  C11D17/0047 ,  C11D17/006 ,  C11D3/222 ,  A61K2800/56

摘要： A "single-use" personal care product designed to replace conventional single use products such as small bars of soap, mini-bottles of shampoo, etc. A water soluble foamed polymer structure, such as produced by freeze drying acemannan derived from aloe vera, serves as the carrier for the personal care active ingredient, and provides the bulk to the structure. The dry foamed product has high void volume, good dimensional stability, high surface area, dissolves easily and completely upon exposure to water and hand mechanical action, and leaves no adverse residue on the skin. The product does not require bottling or complex wrapping, and is much more economical and environmentally friendly than the conventional single use products it replaces. The product can be conveniently carried in a purse or pocket, so that a consumer need never be without his/her favorite personal care products.

摘要翻译： 一种“一次性”个人护理产品，旨在取代常规的单一用途产品，如小肥皂皂，迷你瓶洗发水等。水溶性发泡聚合物结构，如通过冷冻干燥来自芦荟的acemannan， 作为个人护理活性成分的载体，并为结构提供散装。 干燥的发泡产品具有高空隙体积，良好的尺寸稳定性，高表面积，暴露于水和手部机械作用下容易和完全溶解，并且不会在皮肤上留下不良残留物。 该产品不需要装瓶或复杂的包装，并且比其替代的常规单一使用产品更经济和环保。 该产品可以方便地携带在钱包或口袋中，使得消费者不需要没有他/她最喜欢的个人护理产品。

公开(公告)号：US6025005A

公开(公告)日：2000-02-15

申请号：US932742

申请日：1997-09-17

申请人： Wilhelm Pickenhagen ,  Axel Schoning ,  Sabine Widder ,  Dirk Lauven

发明人： Wilhelm Pickenhagen ,  Axel Schoning ,  Sabine Widder ,  Dirk Lauven

IPC分类号： C11B9/00 ,  A23L1/22

CPC分类号： C11B9/0061 ,  C11B9/0011

摘要： There is described the utilization of thiocarbonic acid or carbothioic acid of the general formula ##STR1## R=Methyl, Ethyl, Propyl, Phenyl as an aroma and/or flavor substance. Further, aroma and/or flavor substance compositions are described, which have a content of thiocarbonic acid or carbothioic acids of the general formula I. It is preferred that the content of the thiocarbonic acid or carbothioic acids are between 10.sup.-6 and 5.times.10.sup.-4. Tropical aromas and scent substances in particular can be positively influenced olfactorily and sensorily.

摘要翻译： 描述了通式R =甲基，乙基，丙基，苯基作为芳香和/或调味物质的硫代碳酸或硫代酸的利用。 此外，描述了具有通式I的硫代碳酸或硫代酸的含量的芳香和/或风味物质组合物。优选硫代碳酸或硫代酸的含量为10-6和5×10-4 。 特别是热带香气和气味物质可以嗅觉和感觉地积极地影响。

公开(公告)号：US5981792A

公开(公告)日：1999-11-09

申请号：US31131

申请日：1998-02-26

申请人： Jurgen Vollhardt

发明人： Jurgen Vollhardt

IPC分类号： C07C67/08 ,  C07C67/293 ,  C07C69/025 ,  C07C69/145 ,  C07C67/00 ,  C07C67/02 ,  C07C69/76

CPC分类号： C07C67/08 ,  C07C67/293

摘要： The process for preparing 1-functional allyl alcohol carboxylic esters comprises reacting a 3-functional allyl alcohol with the anhydride of the carboxylic acid at temperatures above 100.degree. C. in the presence of metal compounds of transition groups V to VII, namely at temperatures of 100-200.degree. C., preferably 130-150.degree. C. As metal compounds, it is possible to use oxidic metal compounds in the highest or at least second highest oxidation state of the transition metals, for example tungstic acid or its salts and/or tungsten(VI) oxide and/or molybdenum(V) oxide and/or molybdenum(VI) oxide and/or rhenium(VII) oxide. The 3-functional allyl alcohol and the carboxylic anhydride are advantageously used in equimolar amounts, if desired with a slight excess of anhydride, and an alkali metal salt of a weak acid, for example sodium carbonate or sodium acetate, can be added to the reaction mixture in an amount sufficient to trap free protons.

摘要翻译： 制备1-官能烯丙醇羧酸酯的方法包括在过渡基团V至VII的金属化合物存在下，在高于100℃的温度下，即3-乙烯基醇与羧酸酐反应，即在 100-200℃，优选130-150℃。作为金属化合物，可以使用过渡金属的最高或至少第二高氧化态的氧化金属化合物，例如钨酸或其盐和/ 或氧化物（V）氧化物和/或氧化钼（V）和/或氧化钼（VI）和/或氧化铼（VII）。 如果需要，3-官能的烯丙醇和羧酸酐有利地以等摩尔量的使用，稍微过量的酸酐，并且可以向反应中加入弱酸的碱金属盐，例如碳酸钠或乙酸钠 混合物的量足以捕获游离质子。

公开(公告)号：US07247295B2

公开(公告)日：2007-07-24

申请号：US10381386

申请日：2002-06-19

申请人： Gerhard Schmaus ,  Martina Herrmann ,  Holger Joppe

发明人： Gerhard Schmaus ,  Martina Herrmann ,  Holger Joppe

IPC分类号： A61K7/32 ,  A61K7/00

CPC分类号： A61Q15/00 ,  A01N31/02 ,  A61K8/345

摘要： The invention relates to a method for inhibiting the growth of organisms causing body odor on a human or animal body. The invention comprises the following step: topical application of 1,2-decanediol, wherein the amount of 1,2-decanediol applied is sufficient to inhibit the growth of organisms forming body odor at the site of application.

摘要翻译： 本发明涉及一种抑制人体或动物身体引起体臭的生物生长的方法。 本发明包括以下步骤：局部施用1,2-癸二醇，其中施用的1,2-癸二醇的量足以抑制在施用部位形成体臭的生物的生长。

公开(公告)号：US06083529A

公开(公告)日：2000-07-04

申请号：US59320

申请日：1998-04-13

申请人： Robert P. Manzo ,  Jurgen Vollhardt ,  Nisha Malkan ,  Gary Friars

发明人： Robert P. Manzo ,  Jurgen Vollhardt ,  Nisha Malkan ,  Gary Friars

IPC分类号： A61K8/14 ,  A61K8/73 ,  A61K9/127 ,  A61K9/133 ,  A61K9/14 ,  A61Q1/12

CPC分类号： A61K8/14 ,  A61K8/732 ,  A61K9/127 ,  A61K9/146 ,  A61Q1/12 ,  Y10S977/801 ,  Y10S977/907 ,  Y10S977/915 ,  Y10S977/926

摘要： A stable dry powder skin care powder having prolonged and controlled release properties, useful as baby powders, body talcs, deodorizing powders, OTC eczema preparations, foot powders, anti-fungal powders, etc. The dry powder is preferably prepared by a process comprising spray-drying a mixture of liposome encapsulated active agent, starch and maltodextrin. The particle is designed so that activity of, e.g., an anti-inflammatory agent such as Dragosantol.RTM. can be specifically triggered by skin conditions, such as moisture, for optimal timing of delivery.

摘要翻译： 具有延长和控制释放性能的稳定的干粉护肤粉，可用作婴儿粉末，身体滑石，除臭粉末，OTC湿疹制剂，足部粉末，抗真菌粉末等。干燥粉末优选通过包括喷雾 混合脂质体包裹的活性剂，淀粉和麦芽糖糊精。 该颗粒被设计成使得例如Dragosantol TM等抗炎剂的活性可以由皮肤状况例如水分特异性触发，以达到最佳的递送时间。