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29 条记录 (耗时 0.014 秒)

    Solid, storage-stable, germicidal, pre-iodine composition
    2.
    发明授权
    Solid, storage-stable, germicidal, pre-iodine composition 失效
    固体，储存稳定，杀菌，预碘组合物

    公开(公告)号：US5232914A

    公开(公告)日：1993-08-03

    申请号：US677589

    申请日：1991-03-29

    申请人： Jack H. Fellman

    发明人： Jack H. Fellman

    IPC分类号： A61K33/18 ,  A01N59/12 ,  A61K31/70 ,  A61P17/00

    CPC分类号： A61K33/18 ,  A01N59/12

    摘要： A solid, storage-stable, germicidal, pre-iodine composition comprises in dry admixture with each other a solid oxy-compound of iodine, a solid reducing agent for the oxy-compound of iodine, and a solid desiccant used in amount sufficient to combine during the storage cycle of the composition with ambient and/or endogenous water. The oxy-compounds of iodine are iodic acid, iodine pentoxide, potassium iodate and sodium iodate. Preferred reducing agents are ascorbic acid, dihydroxy fumaric acid, the thiol sugars and cysteine. A preferred combination desiccant and iodine solvating agent is polyvinyl pyrrollidone having a molecular weight of from 10,000 to 1,000,000.The composition is storage-stable for an indefinite period. Upon the addition of water, the oxy-compound of iodine is reduced to nascent iodine, which, in application, serves its well-known germicidal function.

    摘要翻译： 固体，储存稳定，杀菌，预碘组合物包含以下物质彼此干燥混合的固体氧化合物的碘，碘的氧化合物的固体还原剂和固体干燥剂，其用量足以组合 在组合物与环境和/或内源水的储存循环期间。 碘的氧化合物是碘酸，五氧化二磷，碘酸钾和碘酸钠。 优选的还原剂是抗坏血酸，二羟基富马酸，硫醇糖和半胱氨酸。 优选的组合干燥剂和碘溶剂是分子量为10,000至1,000,000的聚乙烯基吡咯烷酮。 该组合物在无限期存储稳定。 加入水后，碘的氧化合物被还原成新生的碘，其在应用中可用于其众所周知的杀菌功能。

    Method of detecting AIDS virus infection
    4.
    发明授权
    Method of detecting AIDS virus infection 失效
    检测艾滋病毒感染的方法

    公开(公告)号：US4904581A

    公开(公告)日：1990-02-27

    申请号：US877609

    申请日：1986-06-23

    申请人： Denis R. Burger ,  Andrew S. Goldstein

    发明人： Denis R. Burger ,  Andrew S. Goldstein

    IPC分类号： C07K16/10

    CPC分类号： C07K16/1045 ,  Y10S435/974 ,  Y10S530/808 ,  Y10S530/809 ,  Y10S530/864

    摘要： A method is disclosed for detecting the presence of HTLV III infected cells in a medium. The method comprises contacting the medium with monoclonal antibodies against an antigen produced as a result of the infection and detecting the binding of the antibodies to the antigen. The antigen may be a gene product of the HTLV III virus or may be bound to such gene product. On the other hand the antigen may not be a viral gene product but may be produced as a result of the infection and may further be bound to a lymphocyte. The medium may be a human body fluid or a culture medium. A particular embodiment of the present method involves a method for determining the presence of a AIDS virus in a person. The method comprises combining a sample of a body fluid from the person with a monoclonal antibody that binds to an antigen produced as a result of the infection and detecting the binding of the monoclonal antibody to the antigen. The presence of the binding indicates the presence of a AIDS virus infection. Also disclosed are novel monoclonal antibodies, noval compositions of matter, and novel diagnostic kits.

    摘要翻译： 公开了一种用于检测培养基中HTLV III感染细胞的存在的方法。 所述方法包括使所述培养基与针对感染结果产生的抗原的单克隆抗体接触并检测抗体与抗原的结合。 抗原可以是HTLV III病毒的基因产物，或者可以与该基因产物结合。 另一方面，抗原可能不是病毒基因产物，但可以作为感染的结果产生，并且可能进一步结合淋巴细胞。 培养基可以是人体液或培养基。 本方法的一个具体实施方案涉及一种用于确定个体中AIDS病毒存在的方法。 该方法包括将来自该人的体液样品与结合与感染结果产生的抗原结合的单克隆抗体并检测单克隆抗体与抗原的结合。 结合物的存在表明艾滋病病毒感染的存在。 还公开了新型单克隆抗体，物质的noval组合物和新型诊断试剂盒。

    Sample volume control for lateral flow chromatography
    6.
    发明授权
    Sample volume control for lateral flow chromatography 失效
    侧流色谱的样品体积控制

    公开(公告)号：US6008056A

    公开(公告)日：1999-12-28

    申请号：US864758

    申请日：1997-05-28

    申请人： Thomas Thieme

    发明人： Thomas Thieme

    IPC分类号： G01N30/90 ,  G01N33/558

    CPC分类号： G01N33/558 ,  G01N30/90 ,  Y10S435/805 ,  Y10S435/81 ,  Y10S435/97 ,  Y10S436/805 ,  Y10S436/81

    摘要： A method of assaying a preselected volume of sample on an chromatographic strip includes providing a sample receiving reservoir. This reservoir can receive a preselected volume of sample or a preselected volume of sample and reagent. The sample receiving reservoir has an overflow outlet. A moat is communicated to the overflow outlet of the sample receiving reservoir for receiving the sample or sample and reagent when the sample receiving reservoir is full. The mixed sample or sample and reagent fill the sample receiving reservoir, and discharge the excess sample through the overflow outlet to the moat. The sample receiving reservoir having the preselected volume of sample or sample and reagent is discharged on the chromatographic strip for assay. Provision is made for adding a density adding solute which is neutral to the chromatographic strip, the density adding solute occupying the sample receiving reservoir. As a consequence, dense sample first occupies the sample receiving reservoir with less dense excess sample being rejected.

    摘要翻译： 在色谱条上测定样品的预选体积的方法包括提供样品接收容器。 该储存器可以接收预选量的样品或预选量的样品和试剂。 样品接收容器具有溢出口。 当样品接收容器满时，将护城河传送到样品接收容器的溢流出口以接收样品或样品和试剂。 混合样品或样品和试剂填充样品接收容器，并将多余的样品通过溢流出口排放到护城河。 具有预先选定体积的样品或样品和试剂的样品接收容器在色谱条上排出​​用于测定。 规定加入密度添加溶质，对色谱条中性，密度添加溶质占据样品接收储层。 因此，密集样品首先占据样品接收储层，而不太密集的多余样品被拒绝。

    Flexible centrifuge tube having bio-containment function
    7.
    发明授权
    Flexible centrifuge tube having bio-containment function 失效
    灵活的离心管具有生物遏制功能

    公开(公告)号：US5859374A

    公开(公告)日：1999-01-12

    申请号：US886562

    申请日：1997-07-01

    申请人： Ronald William Mink ,  Andrew Sherman Goldstein

    发明人： Ronald William Mink ,  Andrew Sherman Goldstein

    IPC分类号： B01L3/00 ,  B01L3/14 ,  G01N1/00

    CPC分类号： B01L3/505 ,  B01L3/5021

    摘要： An apparatus and process for transporting and discharging biohazardous materials is disclosed. A vial is provided having an interior for receiving biohazardous contents. The vial is sealed at one end by a frangible tip for forming an opening in the vial upon breaking of the frangible tip. The vial includes a cap at the opposite end of the vial for sealing the vial when a biohazardous sample contained in a porous absorbent member is placed interior of the vial. A centrifuge tube is provided with an upper opening having a dimension to be plugged when the vial is placed into the centrifuge tube. The centrifuge tube has flexible sidewalls to permit digital manipulation of the frangible tip of the vial by the sidewalls of the centrifuge tube. The vial is placed within the centrifuge tube to plug the tube. Once the vial is within the tube, the tube is digitally manipulated to break the frangible tip of the vial by compressing sidewalls of the centrifuge tube to break the frangible tip of the vial interior of the centrifuge tube. Thereafter, centrifuging the centrifuge tube and vial with broken frangible tip occurs. This causes the biohazardous material to discharge from the porous absorbent member and vial into the centrifuge tube for further processing.

    摘要翻译： 公开了用于运输和排放生物危害材料的装置和方法。 提供具有用于接收生物危害内容物的内部的小瓶。 小瓶在一端用易碎的尖端密封，用于在破裂尖端时在小瓶中形成开口。 小瓶包括在小瓶的相对端的盖子，用于当容纳在多孔吸收件中的生物危险样品置于小瓶内部时密封小瓶。 离心管设置有上部开口，当小瓶被放入离心管中时，其具有要被堵塞的尺寸。 离心管具有柔性侧壁，以允许通过离心管的侧壁数字操纵小瓶的易碎尖端。 将小瓶放置在离心管内以堵塞管。 一旦小瓶在管内，则通过压缩离心管的侧壁以破坏离心管的小瓶内部的易碎尖端，数字地操作管以破坏小瓶的易碎尖端。 此后，离心分离管和破碎的脆性尖端的小瓶出现。 这导致生物危险材料从多孔吸收件和小瓶排出到离心管中用于进一步处理。

    Regulated expression of heterologous genes in plants and transgenic fruit with a modified ripening phenotype
    8.
    发明授权
    Regulated expression of heterologous genes in plants and transgenic fruit with a modified ripening phenotype 失效
    调节异源基因在植物和转基因水果中的表达，具有修饰的成熟表型

    公开(公告)号：US5859330A

    公开(公告)日：1999-01-12

    申请号：US331355

    申请日：1994-10-27

    申请人： Richard Keith Bestwick ,  Adolph J. Ferro

    发明人： Richard Keith Bestwick ,  Adolph J. Ferro

    IPC分类号： C07K14/415 ,  C12N9/14 ,  C12N15/82 ,  A01H5/00 ,  A01H5/08

    CPC分类号： C07K14/415 ,  C12N15/8216 ,  C12N15/8222 ,  C12N15/8235 ,  C12N15/8249 ,  C12N9/14

    摘要： The present invention relates to chimeric genes having (i) a DNA sequence encoding a product that is effective to reduce ethylene biosynthesis in fruit from the plant, and (ii) a promoter whose expression is induced during fruit ripening or by ethylene synthesis by the fruit, where the DNA sequence is heterologous to the promoter and the DNA sequence is operably linked to the promoter to enable expression of the product. The invention describes vectors and transgenic plants, vegetables, flowers and fruits carrying the chimeric gene, as well as methods related thereto.

    摘要翻译： 本发明涉及嵌合基因，其具有（i）编码有效减少来自植物的果实中的乙烯生物合成的产物的DNA序列，和（ii）在果实成熟期间诱导其表达或通过水果的乙烯合成的启动子 ，其中DNA序列与启动子是异源的，并且DNA序列可操作地连接到启动子以使得能够表达产物。 本发明描述了携带嵌合基因的载体和转基因植物，蔬菜，花和果实以及与之相关的方法。

    Elastic barrier permeability testing device and method of use
    10.
    发明授权
    Elastic barrier permeability testing device and method of use 失效
    弹性阻隔渗透性试验装置及其使用方法

    公开(公告)号：US5073482A

    公开(公告)日：1991-12-17

    申请号：US209373

    申请日：1988-06-21

    申请人： Andrew S. Goldstein

    发明人： Andrew S. Goldstein

    IPC分类号： C12Q1/68 ,  C12Q1/70 ,  G01N15/08

    CPC分类号： G01N15/08 ,  C12Q1/6888 ,  C12Q1/70

    摘要： A device for testing an elastic membrane for permeability ot submicroscopic particles. The device has a first chamber to contain the particles in a fluid medium; a second chamber to contain a reagent for detecting the presence of any of the particles; suitable structure for mounting the membrane between the chambers in a fluid-tight manner so that the membrane separates the chambers; and a mechanism for applying stress to the membrane.

    摘要翻译： 用于测试弹性膜用于亚显微粒子的渗透性的装置。 该装置具有第一室以将颗粒容纳在流体介质中; 第二室，容纳用于检测任何颗粒的存在的试剂; 用于以流体密封的方式将膜安装在室之间的适当结构，使得膜分离室; 以及向膜施加应力的机构。