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公开(公告)号：US07777020B2
公开(公告)日：2010-08-17
申请号：US11203127
申请日：2005-08-15
Applicant: Maurice Moncany , Luc Montagnier
Inventor： Maurice Moncany , Luc Montagnier
CPC classification number: C07K14/005 , A61K38/00 , A61K39/00 , C12N2740/15022 , C12N2740/16022 , C12Q1/703 , G01N2333/16 , Y10S435/974 , Y10S435/975
Abstract: This invention encompasses an env nucleic acid product produced by a process comprising providing a sample containing HIV-1 nucleic acid and amplifying the nucleic acid using primer pairs.
Abstract translation: 本发明包括通过包括提供含有HIV-1核酸的样品并使用引物对扩增核酸的方法产生的env核酸产物。
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2.发明申请公开(公告)号：US20090011443A1
公开(公告)日：2009-01-08
申请号：US12165808
申请日：2008-07-01
Applicant: Daniel P. Collins
Inventor： Daniel P. Collins
IPC: G01N33/543
CPC classification number: G01N33/54306 , Y10S435/96 , Y10S435/968 , Y10S435/971 , Y10S435/973 , Y10S435/974 , Y10S435/975
Abstract: Methods and kits for simultaneously measuring both members of a binding pair are described.
Abstract translation: 描述了用于同时测量结合对的两个成员的方法和试剂盒。
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公开(公告)号：US20080187904A1
公开(公告)日：2008-08-07
申请号：US12026740
申请日：2008-02-06
Applicant: Christoph Seidel , Ursula-Henrike Wienhues , Eva Hoss
Inventor： Christoph Seidel , Ursula-Henrike Wienhues , Eva Hoss
CPC classification number: C07K14/005 , C07F15/0053 , C12N2740/16122 , C12N2770/24222 , G01N33/532 , G01N33/533 , G01N33/54306 , G01N33/6854 , G01N33/6878 , G01N33/743 , G01N33/92 , Y02P20/55 , Y10S435/974 , Y10S435/975 , Y10S436/811 , Y10S436/82 , Y10S530/82
Abstract: The invention concerns a process for the production of metal chelate-labelled peptide antigens, peptides obtainable by this process and their use in an immunological method of detection.
Abstract translation: 本发明涉及一种生产金属螯合物标记的肽抗原的方法，可通过该方法获得的肽及其在免疫学检测方法中的应用。
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4.发明授权Recombinant DNA constructs for GAG polypeptides and polypeptides produced thereby 失效用于GAG多肽和由此产生的多肽的重组DNA构建体公开(公告)号：US07408053B1
公开(公告)日：2008-08-05
申请号：US08442750
申请日：1995-05-17
Applicant: Paul A. Luciw , Dino Dina
Inventor： Paul A. Luciw , Dino Dina
IPC: C07H21/04
CPC classification number: C07K14/005 , A61K38/00 , C07K2319/00 , C12N9/0089 , C12N15/81 , C12N15/85 , C12N2740/16222 , C12N2800/108 , C12N2830/002 , C12N2830/15 , C12N2830/36 , C12N2830/55 , C12N2830/702 , C12Q1/703 , Y10S435/948 , Y10S435/974
Abstract: Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.
Abstract translation: 提供多核苷酸序列用于诊断与淋巴结病综合征和/或获得性免疫缺陷综合征相关的人宿主中的逆转录病毒感染的存在，用于表达多肽和使用多肽来制备抗体，其中多肽和抗体可以是 用作诊断试剂或用于治疗，例如疫苗和被动免疫。 这些序列提供与所指示的综合征相关的病毒感染因子的检测，并可用于表达抗原多肽。
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5.发明授权Antibodies which bind with proteins of human immunodeficiency virus type 1 (HIV-1), and immune complexes comprising proteins of HIV-1 失效与人类免疫缺陷病毒1型（HIV-1）的蛋白质结合的抗体和包含HIV-1蛋白的免疫复合物公开(公告)号：US07122188B1
公开(公告)日：2006-10-17
申请号：US08067148
申请日：1993-05-26
Applicant: Luc Montagnier , Jean-Claude Chermann , Francoise Barre-Sinoussi , Francoise Vezinet-Bruil , Christine Rouzioux , Willy Rozenbaum , Charles Dauguet , Jacqueline Gruest , Marie-Theresa Nugeyre , Francoise Rey , Claudine Axler-Blin , Solange Chamaret
Inventor： Luc Montagnier , Jean-Claude Chermann , Francoise Barre-Sinoussi , Francoise Vezinet-Bruil , Christine Rouzioux , Willy Rozenbaum , Charles Dauguet , Jacqueline Gruest , Marie-Theresa Nugeyre , Francoise Rey , Claudine Axler-Blin , Solange Chamaret
IPC: A61K39/42
CPC classification number: C07K14/005 , C12N7/00 , C12N2740/16051 , C12N2740/16222 , Y10S435/974 , Y10S930/221
Abstract: This invention provides antibodies which bind with p12 and p18 proteins of a human immunodeficiency virus type 1 (HIV-1), antibodies which bind with immune complexes comprising p12 or p18 proteins of HIV-1, mixtures of antibodies which bind with p12, p15, p18, p25, p36, p42, and p80 proteins of HIV-1, mixtures of antibodies which bind with immune complexes comprising the HIV-1 proteins, immune complexes comprising p12 or p18 proteins of HIV-1, and methods for production of antibodies against p2 or p18 proteins of HIV-1.
Abstract translation: 本发明提供了与人免疫缺陷病毒1型（HIV-1）的p12和p18蛋白结合的抗体，其与包含HIV-1的p12或p18蛋白的免疫复合物结合的抗体，与p12，p15结合的抗体混合物， HIV-1的p18，p25，p36，p42和p80蛋白，与包含HIV-1蛋白的免疫复合物结合的抗体的混合物，包含HIV-1的p12或p18蛋白的免疫复合物，以及用于产生针对 p2或p18蛋白。
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Patent Agency Ranking
6.发明授权NUCLEOTIDE SEQUENCES DERIVED FROM THE GENOME OF RETROVIRUSES OF THE HIV-1, HIV-2 AND SIV TYPE, AND THEIR USES IN PARTICULAR FOR THE AMPLIFICATION OF THE GENOMES OF THESE RETROVIRUSES AND FOR THE IN VITRO DIAGNOSIS OF THE DISEASES DUE TO THESE VIRUSES 失效从HIV-1，HIV-2和SIV类型的病毒基因组衍生的核苷酸序列，以及它们特别用于扩增这些病毒的基因的病毒和由于这些病毒引起的疾病的体外诊断公开(公告)号：US07078516B1
公开(公告)日：2006-07-18
申请号：US08472928
申请日：1995-06-07
Applicant: Maurice Moncany , Luc Montagnier
Inventor： Maurice Moncany , Luc Montagnier
IPC: C07H21/04
CPC classification number: C07K14/005 , A61K38/00 , A61K39/00 , C12N2740/15022 , C12N2740/16022 , C12Q1/703 , G01N2333/16 , Y10S435/974 , Y10S435/975
Abstract: The invention provides oligonucleotide primers selected from the group consisting of a nucleotide sequence of the gag, vpr, and pol genes of HIV-1 Bru, HIV-1 Mal, HIV-1 Eli, HIV-2 ROD, and SIV MAC; the nef, vif, and vpx genes of HIV-2 ROD and SIV MAC; and the env, nef, vif, and vpu genes of HIV-1 Bru, HIV-1 Mal and HIV-1 Eli and nucleotide sequences complementary thereto.
Abstract translation: 本发明提供选自HIV-1 Bru，HIV-1Mal，HIV-1Eli，HIV-2ROD和SIV MAC的gag，vpr和pol基因的核苷酸序列的寡核苷酸引物; HIV-2 ROD和SIV MAC的nef，vif和vpx基因; 以及HIV-1 Bru，HIV-1 Mal和HIV-1 Eli的env，nef，vif和vpu基因和与其互补的核苷酸序列。
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公开(公告)号：US20050227227A1
公开(公告)日：2005-10-13
申请号：US11145272
申请日：2005-06-03
Applicant: Yeasing Yang , Steven Brentano , Odile Babola , Nathalie Tran , Guy Vernet
Inventor： Yeasing Yang , Steven Brentano , Odile Babola , Nathalie Tran , Guy Vernet
CPC classification number: C07H21/02 , C12Q1/703 , H01L2924/014 , H01L2924/14 , Y10S435/974
Abstract: Sequences of nucleic acid oligonucleotides for amplifying different portions of gag and pol genes of HIV-1 and for detecting such amplified nucleic acid sequences are disclosed. Methods of amplifying and detecting HIV-1 nucleic acid in a biological sample using the amplification oligonucleotides specific for gag and pol target sequences are disclosed.
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8.发明申请公开(公告)号：US20050106161A1
公开(公告)日：2005-05-19
申请号：US10969191
申请日：2004-10-21
Applicant: Erwann Loret
Inventor： Erwann Loret
IPC: G01N33/53 , A61K6/00 , A61K38/00 , A61K39/00 , A61K39/21 , A61K39/39 , A61P31/18 , C07K14/16 , C07K16/10 , G01N33/569
CPC classification number: C07K14/005 , A61K39/00 , A61K39/12 , A61K39/21 , A61K2039/54 , A61K2039/545 , A61K2039/55566 , C12N2740/16322 , C12N2740/16334 , Y10S435/962 , Y10S435/974 , Y10S435/975
Abstract: The invention relates to an anti HIV 1 vaccine comprising the entire or part of the Tat HIV 1 protein, in addition to the identification of said protein in individuals affected by HIV. The Tat protein is a protein of the HIV1 Oyi variant.
Abstract translation: 本发明涉及包含Tat HIV 1蛋白的全部或部分的抗HIV 1疫苗，以及在受HIV感染的个体中鉴定所述蛋白质。 Tat蛋白是HIV1 Oyi变体的蛋白质。
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9.发明申请Polypeptide and nucleotide fragments of HIV-1, HIV-2, and SIV, antibodies, methods of using antibodies, and kits 有权HIV-1，HIV-2和SIV的多肽和核苷酸片段，抗体，使用抗体的方法和试剂盒公开(公告)号：US20050037340A1
公开(公告)日：2005-02-17
申请号：US10862363
申请日：2004-06-08
Applicant: Maurice Moncany , Luc Montagnier
Inventor： Maurice Moncany , Luc Montagnier
IPC: A61K39/00 , A61K39/21 , A61K48/00 , A61P31/18 , C07H21/04 , C07K14/00 , C07K14/155 , C07K14/16 , C07K16/00 , C07K16/10 , C12N15/09 , C12N15/49 , C12Q1/68 , C12Q1/70 , G01N33/569 , G01N33/53 , G01N33/564
CPC classification number: C07K14/005 , A61K38/00 , A61K39/00 , C12N2740/15022 , C12N2740/16022 , C12Q1/703 , G01N2333/16 , Y10S435/974 , Y10S435/975
Abstract: The invention relates to polypeptide fragments of HIV-1, HIV-2, and SIV, antibodies that bind to the polypeptides of the invention, methods of using the antibodies, and kits containing the antibodies. The invention also relates to polynucleotides that encode the polypeptide fragments of the invention.
Abstract translation: 本发明涉及结合本发明多肽的HIV-1，HIV-2和SIV的多肽片段，使用抗体的方法和含有该抗体的试剂盒。 本发明还涉及编码本发明的多肽片段的多核苷酸。
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10.发明授权Use of check surfaces for identifying disturbing samples in a detection procedure 失效在检测程序中使用检查表面识别干扰样品公开(公告)号：US06815217B2
公开(公告)日：2004-11-09
申请号：US09463547
申请日：2000-01-21
Applicant: Johann Karl , Helmut Lenz , Friedemann Krause , Peter Finckh , Hans Hornauer , Johann Berger
Inventor： Johann Karl , Helmut Lenz , Friedemann Krause , Peter Finckh , Hans Hornauer , Johann Berger
IPC: G01N33553
CPC classification number: G01N33/54366 , C12Q1/6834 , Y10S435/805 , Y10S435/81 , Y10S435/962 , Y10S435/973 , Y10S435/974
Abstract: A solid phase with at least one test area is described which contains reagents for the detection of at least one analyte in a sample, wherein the solid phase additionally comprises at least one control area for the detection of interfering reactions.
Abstract translation: 描述了具有至少一个测试区域的固相，其包含用于检测样品中至少一种分析物的试剂，其中所述固相还包含用于检测干扰反应的至少一个控制区域。
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