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公开(公告)号：US08271138B2
公开(公告)日：2012-09-18
申请号：US12209097
申请日：2008-09-11
申请人： Walter W. Eliuk , Ronald H. Rob , Richard L. Jones , Dustin Deck
发明人： Walter W. Eliuk , Ronald H. Rob , Richard L. Jones , Dustin Deck
IPC分类号： G05B15/00
CPC分类号： B66C1/42
摘要： Gripper devices for handling syringes and automated pharmacy admixture systems (APASs) that utilize such gripper devices. The gripper devices may include various gripper finger profiles, substantially tapered or angled gripping surfaces and/or gripper fingers interleaving to reduce radial distortion of the syringes to be grasped while opposing axial motion of the syringes.
摘要翻译： 用于处理注射器的夹持装置和利用这种夹持装置的自动化药剂混合系统（APAS）。 夹持装置可以包括各种夹持器手指型材，基本上呈锥形或成角度的抓握表面和/或夹持器手指交错，以减少在注射器的轴向运动的同时相对于被抓握的注射器的径向变形。
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公开(公告)号：US08267129B2
公开(公告)日：2012-09-18
申请号：US11937846
申请日：2007-11-09
申请人： Thom Doherty , Walter W. Eliuk , Richard L. Jones
发明人： Thom Doherty , Walter W. Eliuk , Richard L. Jones
IPC分类号： B65B39/00
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2044 , A61J1/2055 , A61J1/2065 , A61J3/002 , A61J2200/10 , B65B3/003
摘要： Some methods and related apparatus for manipulating a fluid conduit for insertion into a substantially re-sealable membrane include determining an orientation and position of a fluid conduit relative to the membrane. In an illustrative example, a syringe needle having a beveled leading edge may be manipulated by an automated device to be oriented and aligned with an aperture made upon a previous insertion of a needle into a membrane. In some examples, a predetermined number of insertions may be made in the same aperture by aligning and orienting one or more needles with the aperture. In some examples, multiple needle insertions may be controlled to produce apertures that are substantially spaced apart. Such procedures may, for example, advantageously extend the integrity of the membrane against leakage and/or contamination.
摘要翻译： 用于操纵用于插入基本上可再密封的膜的流体导管的一些方法和相关装置包括确定流体导管相对于膜的取向和位置。 在一个说明性的例子中，具有倾斜前缘的注射器针可以通过自动化装置来操纵，以被定向并与先前将针插入膜中时制成的孔对齐。 在一些示例中，通过使一个或多个针与孔对准和定向，可以在相同的孔中形成预定数量的插入。 在一些实例中，可以控制多个针插入物以产生基本间隔开的孔。 这样的程序可以例如有利地延长膜的完整性以防止泄漏和/或污染。
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公开(公告)号：US20100241270A1
公开(公告)日：2010-09-23
申请号：US12628884
申请日：2009-12-01
申请人： Walter W. Eliuk , Ronald H. Rob , Lance R. Mlodzinski , Alex H. Reinhardt , Thom Doherty , Dustin Deck
发明人： Walter W. Eliuk , Ronald H. Rob , Lance R. Mlodzinski , Alex H. Reinhardt , Thom Doherty , Dustin Deck
IPC分类号： G06F7/00
CPC分类号： A61J1/20 , A61J1/10 , A61J1/201 , A61J1/2096 , A61J3/002 , A61J2200/10 , A61M5/3286 , A61M5/3291 , B01F13/1072
摘要： In a preferred implementation, an automated pharmacy admixture system (APAS) prepares intermediary IV bags as drug sources for creating highly diluted patient doses in syringes. During the compounding process the APAS may align needles with a vial seal opening so as to ensure repeated entry through the same vial puncture site via precise control of needle position, needle bevel orientation, and needle entry speed. These techniques can in certain implementations substantially improve bung pressure sealing and reduced particulate generation. The APAS optionally creates drug order queues for incoming drug orders wherein the orders can be sorted by priority, drug type or patient location. A phantom queue can be combined with the incoming drug order queues to include frequently used medicaments to minimize operator loading of the APAS.
摘要翻译： 在优选实施方案中，自动化药剂混合系统（APAS）制备中间体IV袋作为在注射器中产生高度稀释的患者剂量的药物来源。 在复合过程中，APAS可以将针与小瓶密封开口对准，以便通过精确控制针位置，针斜度方向和针入口速度来确保重复进入相同的小瓶穿刺部位。 这些技术在某些实施方式中可以显着改善密封压力和减少颗粒物的产生。 APAS可选地为进入的药物订单创建药物订单队列，其中可以按优先级，药物类型或患者位置对顺序进行排序。 幻影队列可以与进入的药物订单队列组合，以包括经常使用的药物，以最大限度地减少APAS的操作员负载。
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公开(公告)号：US20090126825A1
公开(公告)日：2009-05-21
申请号：US12271828
申请日：2008-11-14
申请人： Walter W. Eliuk , Ronald H. Rob , Dustin Deck , Richard L. Jones , Thom Doherty
发明人： Walter W. Eliuk , Ronald H. Rob , Dustin Deck , Richard L. Jones , Thom Doherty
摘要： Automated system and techniques for controlling fluid transfers among medical containers such as syringes, vials and IV bag are disclosed. In one aspect, an automated method for substantially balancing a pressure within a medical container such as a vial with ambient pressure using a fluid transfer device such as a needled syringe is disclosed. In another aspect, an automated method for substantially removing a volume of air from a medical container such as an IV bag using a fast pull technique is disclosed.
摘要翻译： 公开了用于控制诸如注射器，小瓶和IV袋的医疗容器之间的流体转移的自动化系统和技术。 一方面，公开了一种使用诸如针刺注射器之类的流体转移装置将医疗容器（例如小瓶）内的压力与环境压力基本平衡的自动化方法。 另一方面，公开了一种使用快速拉拔技术从医疗容器（例如IV袋）中大体上去除一定体积的空气的自动化方法。
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公开(公告)号：US20080114328A1
公开(公告)日：2008-05-15
申请号：US11937846
申请日：2007-11-09
申请人： Thom Doherty , Walter W. Eliuk , Richard L. Jones
发明人： Thom Doherty , Walter W. Eliuk , Richard L. Jones
IPC分类号： A61B19/00
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2044 , A61J1/2055 , A61J1/2065 , A61J3/002 , A61J2200/10 , B65B3/003
摘要： Some methods and related apparatus for manipulating a fluid conduit for insertion into a substantially re-sealable membrane include determining an orientation and position of a fluid conduit relative to the membrane. In an illustrative example, a syringe needle having a beveled leading edge may be manipulated by an automated device to be oriented and aligned with an aperture made upon a previous insertion of a needle into a membrane. In some examples, a predetermined number of insertions may be made in the same aperture by aligning and orienting one or more needles with the aperture. In some examples, multiple needle insertions may be controlled to produce apertures that are substantially spaced apart. Such procedures may, for example, advantageously extend the integrity of the membrane against leakage and/or contamination.
摘要翻译： 用于操纵用于插入基本上可再密封的膜的流体导管的一些方法和相关装置包括确定流体导管相对于膜的取向和位置。 在一个说明性的例子中，具有倾斜前缘的注射器针可以通过自动化装置来操纵，以被定向并与先前将针插入膜中时制成的孔对齐。 在一些示例中，通过使一个或多个针与孔对准和定向，可以在相同的孔中形成预定数量的插入。 在一些实例中，可以控制多个针插入物以产生基本间隔开的孔。 这样的程序可以例如有利地延长膜的完整性以防止泄漏和/或污染。
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公开(公告)号：US20140031976A1
公开(公告)日：2014-01-30
申请号：US13950061
申请日：2013-07-24
发明人： Alex H. REINHARDT , Ronald H. Rob
CPC分类号： A61J1/20 , A61J1/10 , A61J3/002 , F04C2270/041 , G06F19/00 , G06F19/3468
摘要： A robotic intravenous automation system, including a robotically controlled holder configured to manipulate an intravenous (IV) bag and a closed system transfer device (CSTD). The controller includes a processor configured to control the holder. The IV bag includes a first fluid port and a second fluid port, and the CSTD includes a CSTD port, a spike adapter that is fluidically separated from the CSTD port, and a flexible member connecting the CSTD port to the spike adapter.
摘要翻译： 一种机器人静脉自动化系统，包括被配置为操纵静脉内（IV）袋和闭合系统传送装置（CSTD）的机器人控制的保持器。 控制器包括配置成控制保持器的处理器。 IV袋包括第一流体端口和第二流体端口，并且CSTD包括CSTD端口，与CSTD端口流体分离的尖峰适配器以及将CSTD端口连接到峰值适配器的柔性构件。
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公开(公告)号：US08571708B2
公开(公告)日：2013-10-29
申请号：US12566037
申请日：2009-09-24
IPC分类号： G06F19/00
CPC分类号： A61J3/002 , A61J1/20 , A61J2205/10 , A61J2205/30 , A61J2205/60 , B01F13/1072 , B65B3/003 , B65B31/024 , G06F19/00 , G06F19/3462 , G07F11/165 , G07F11/44 , G07F11/48 , G07F11/54 , G07F11/62 , G07F17/0092
摘要： An Automated Pharmacy Admixture System (APAS) may include a manipulator that transports medical containers such as bags, vials, or syringes about a substantially aseptic admixing chamber. In a preferred implementation, a gripper assembly is configured to substantially universally grasp and retain syringes, IV bags, and vials of varying shapes and sizes. In an illustrative embodiment, a gripping device may include claws configured to grasp a plurality of different types of IV bags, each type having a different fill port configuration. Embodiments may include a controller adapted to actuate a transport assembly to place a fill port of the bag, vial or syringe into register with a filling port such as a cannula located at a filling station, or be equipped with carousel transport systems that are adapted to convey bags, vials, and syringes to the admixture system and deliver constituted medications in bags, vials or syringes to an egress area.
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公开(公告)号：US20110208350A1
公开(公告)日：2011-08-25
申请号：US13044049
申请日：2011-03-09
IPC分类号： G06F19/00
CPC分类号： A61J1/20 , A61J3/002 , B01F11/0008 , B01F11/0017 , B01F13/1055 , B01F13/1063 , B01F15/00253 , B65B3/003 , B65B31/02 , B65B31/024 , B65B55/16 , B65B59/00 , G06F19/00 , G07F11/002 , G07F11/165 , G07F11/70
摘要： In a preferred embodiment, an Automated Pharmacy Admixture System (APAS) may include a manipulator system to transport medical containers such as bags, vials, or syringes in a compounding chamber regulated to a pressure below atmospheric pressure. In a preferred implementation, the manipulator system is configured to grasp and convey syringes, IV bags, and vials of varying shapes and sizes from a storage system in an adjacent chamber regulated at a pressure above atmospheric pressure. Various embodiments may include a controller adapted to actuate the manipulator system to bring a fill port of an IV bag, vial, or syringe into register with a filling port at a fluid transfer station in the chamber. A preferred implementation includes a sanitization system that can substantially sanitize a bung on a fill port of a vial or IV bag in preparation for transport to the fluid transfer station.
摘要翻译： 在优选的实施方案中，自动药物外加剂系统（APAS）可以包括操纵器系统，以将医疗容器例如袋，小瓶或注射器输送到调节到低于大气压的压力的配混室中。 在优选的实施方案中，机械手系统构造成从在高于大气压力的压力下调节的相邻室中的存储系统中抓住并传送不同形状和尺寸的注射器，IV袋和小瓶。 各种实施例可以包括适于致动操纵器系统以使IV袋，小瓶或注射器的填充端口与腔室中的流体转移站处的填充口对准的控制器。 优选的实施方案包括消毒系统，其可以基本上消毒小瓶或IV袋的填充口上的栓，以准备运输到流体转运站。
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公开(公告)号：US20080199353A1
公开(公告)日：2008-08-21
申请号：US12035850
申请日：2008-02-22
申请人： Lance R. Mlodzinski , Walter W. Eliuk , Alex H. Reinhardt , Ronald H. Rob , Robert Keith Davidson
发明人： Lance R. Mlodzinski , Walter W. Eliuk , Alex H. Reinhardt , Ronald H. Rob , Robert Keith Davidson
CPC分类号： A61L2/10 , A61J1/20 , A61J3/002 , A61J2200/74 , A61J2205/10 , A61J2205/30 , A61J2205/60 , B01F13/1072 , B65B3/003 , B65B55/08 , G06F19/3462 , G06F19/3468 , G07F11/165 , G07F11/44 , G07F11/48 , G07F11/54 , G07F11/62 , G07F17/0092 , Y10S604/905
摘要： Systems and methods to reduce bioburden on at least a portion of a fluid transfer port include supplying a dose of radiation to the portion in optical communication with at least one source of radiation. In an illustrative example, a medical container, such as a vial or IV bag, receives a dose of ultraviolet (UV) energy substantially at a predetermined region of a fluid transfer site. In some examples, such a sanitization process may precede a fluid transfer operation in which a fluid is transferred into or out of the medical container by passing through the sanitized region. Such fluid transfers may be used in automated or semi-automated pharmaceutical processes, such as drug reconstitution. Various embodiments may further include one or more seal assemblies, each seal assembly having an aperture through which the radiation dose is supplied from the source to a controlled region on the fluid transfer port.
摘要翻译： 减少流体传送端口的至少一部分上的生物负载的系统和方法包括向与至少一个辐射源光通信的部分提供一定剂量的辐射。 在说明性示例中，诸如小瓶或IV袋的医疗容器基本上在流体输送部位的预定区域处接收一定量的紫外线（UV）能量。 在一些示例中，这种消毒过程可以在流体转移操作之前，其中通过通过消毒区域将流体转移到或流出医疗容器。 这种流体转移可以用于自动化或半自动化药物过程，例如药物重建。 各种实施例还可以包括一个或多个密封组件，每个密封组件具有孔，辐射剂量通过该孔从源供应到流体传送端口上的受控区域。
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公开(公告)号：US08225824B2
公开(公告)日：2012-07-24
申请号：US12271828
申请日：2008-11-14
申请人： Walter W. Eliuk , Ronald H. Rob , Dustin Deck , Richard L. Jones , Thom Doherty
发明人： Walter W. Eliuk , Ronald H. Rob , Dustin Deck , Richard L. Jones , Thom Doherty
IPC分类号： B65B1/30
摘要： Automated system and techniques for controlling fluid transfers among medical containers such as syringes, vials and IV bag are disclosed. In one aspect, an automated method for substantially balancing a pressure within a medical container such as a vial with ambient pressure using a fluid transfer device such as a needled syringe is disclosed. In another aspect, an automated method for substantially removing a volume of air from a medical container such as an IV bag using a fast pull technique is disclosed.
摘要翻译： 公开了用于控制诸如注射器，小瓶和IV袋的医疗容器之间的流体转移的自动化系统和技术。 一方面，公开了一种使用诸如针刺注射器之类的流体转移装置将医疗容器（例如小瓶）内的压力与环境压力基本平衡的自动化方法。 另一方面，公开了一种使用快速拉拔技术从医疗容器（例如IV袋）中大体上去除一定体积的空气的自动化方法。
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