公开(公告)号：US20220153655A1

公开(公告)日：2022-05-19

申请号：US17665243

申请日：2022-02-04

申请人： Lincoln University

发明人： Andriy Podolyan ,  David Rennison ,  Gregory Cook ,  Hong Jie Di ,  Keith Craig Cameron ,  Margaret Anne Brimble ,  Scott Ferguson ,  Robert Starr Ronimus ,  Vincenzo Carbone

IPC分类号： C05G3/90 ,  C07D241/18 ,  C07D237/14 ,  C07D239/34 ,  B09C1/08 ,  C05C9/00 ,  C05C3/00 ,  C02F1/68

摘要： Nitrification inhibitors and uses of same to prevent nitrate leaching or nitrous oxide emissions as well as increase pasture or crop production. The nitrification inhibitors and formulations including same may be used for direct or indirect application to soil or pasture.

公开(公告)号：US11690374B2

公开(公告)日：2023-07-04

申请号：US16324839

申请日：2017-08-03

申请人： Lincoln University

发明人： John Graham Hampton ,  Eline Van Zijll De Jong

IPC分类号： A01N25/12 ,  A01N25/00 ,  A01N63/20

CPC分类号： A01N25/00 ,  A01N25/12 ,  A01N63/20

摘要： The invention provides isolated Erwinia persicina strains with activity against: a) at least one Xanthomonas species, and/or b) at least one Brassicaceae pathogen. In particular the invention provides the isolated E. persicina strains deposited as DSM 32302, DSM 32304, DSM 32305 and DSM 32303. The invention provides compositions comprising one or more strains of the invention. The invention also provides methods of use of one or more strains or compositions of the inventions to control plant pathogens, particularly Xanthomonas campestris pv. campestris.

公开(公告)号：US20230183109A1

公开(公告)日：2023-06-15

申请号：US17596672

申请日：2020-10-12

申请人： LINCOLN UNIVERSITY

发明人： Hong Jie DI ,  Keith Craig CAMERON

IPC分类号： C02F1/52

CPC分类号： C02F1/5245 ,  C02F2101/322

摘要： The use of ferric sulphate or polyferric sulphate to treat liquid animal effluent to reduce methane emissions therefrom.

公开(公告)号：US10004236B2

公开(公告)日：2018-06-26

申请号：US13837735

申请日：2013-03-15

申请人： Travis Robert Glare ,  John Graham Hampton ,  Murray Paul Cox ,  Damian Alexander Bienkowski

发明人： Travis Robert Glare ,  John Graham Hampton ,  Murray Paul Cox ,  Damian Alexander Bienkowski

IPC分类号： A01N63/00 ,  C12N1/20 ,  C12R1/01 ,  A01P7/04

CPC分类号： A01N63/00 ,  C12R1/01

摘要： The invention provides isolated Brevibacillius laterosporus strains with insecticidal activity against at least one Lepidopteraspecies and at least one Dipteraspecies. In particular the invention provides the isolated B. laterosporus strains NMI No. V12/001946, NMI No. V12/001945 and NMI No. V12/001944. The invention provides compositions comprising one or more strain of the invention. The invention also provides methods of use of one or more strains or compositions of the inventions to control pests, particularly insect pests.

公开(公告)号：US20230202941A1

公开(公告)日：2023-06-29

申请号：US18168473

申请日：2023-02-13

申请人： Lincoln University

发明人： Andriy Podolyan ,  David Rennison ,  Gregory Cook ,  Hong Jie Di ,  Keith Craig Cameron ,  Margaret Anne Brimble ,  Scott Ferguson ,  Robert Starr Ronimus ,  Vincenzo Carbone

IPC分类号： C05G3/90 ,  B09C1/08 ,  C02F1/68 ,  C05C3/00 ,  C05C9/00 ,  C07D237/14 ,  C07D239/34 ,  C07D241/18

CPC分类号： C05G3/90 ,  B09C1/08 ,  C02F1/68 ,  C05C3/00 ,  C05C9/00 ,  C07D237/14 ,  C07D239/34 ,  C07D241/18 ,  C02F2103/20

摘要： Nitrification inhibitors and uses of same to prevent nitrate leaching or nitrous oxide emissions as well as increase pasture or crop production. The nitrification inhibitors and formulations including same may be used for direct or indirect application to soil or pasture.

公开(公告)号：US20060089260A1

公开(公告)日：2006-04-27

申请号：US10522948

申请日：2003-08-01

申请人： Jie Di ,  Keith Cameron

发明人： Jie Di ,  Keith Cameron

IPC分类号： A01N25/00

CPC分类号： A01C21/00 ,  C05G3/08 ,  Y02P60/218

摘要： A nitrification inhibitor treatment used as a soil mangement tool on grazed pasture soils. The treatment includes the application of nitrification inhibitors in solution form and/or line particle suspension form and/or in crystalline form to treat the whole area of grazed pasture soils to: reduce nitrate leaching; reduce nitrous oxide emissions; reduce postassium, calcium and magnesium leaching; and increase pasture production in both the animal urine patch areas and non-urine patch areas. The nitrification inhibitors can be applied in conjunction with irrigation water, by a spray vehicle or in a similar way to the application of agricultural chemicals.

摘要翻译： 硝化抑制剂处理用作牧场牧草土壤的土壤管理工具。 该处理包括以溶液形式和/或线粒子悬浮液形式和/或结晶形式施用硝化抑制剂以处理放牧的牧草土壤的整个区域以减少硝酸盐浸出; 减少一氧化二氮排放; 降低钾，钙和镁浸出; 并增加动物尿液贴片区域和非尿液贴片区域的牧草产量。 硝化抑制剂可以与灌溉水，喷雾载体一起使用，也可以与农药的应用相似。

公开(公告)号：US08394623B2

公开(公告)日：2013-03-12

申请号：US12867012

申请日：2009-02-13

申请人： Alison Stewart

发明人： Alison Stewart

IPC分类号： C12N1/14 ,  C12N1/00 ,  A01N63/04 ,  A01N63/00

CPC分类号： A01N63/04 ,  C12R1/885

摘要： The present invention relates to Trichoderma atroviride strains and their use as biological control agents or plant growth promoters. Methods and compositions for biological control of soil borne plant pathogens, and increasing plant yield using T. atroviride are also provided.

摘要翻译： 本发明涉及叶绿体菌株及其作为生物防治剂或植物生长促进剂的用途。 还提供了用于生物防治土壤植物病原体的方法和组合物，以及使用阿特罗里韦提高植物产量。

公开(公告)号：US11578013B2

公开(公告)日：2023-02-14

申请号：US17665243

申请日：2022-02-04

申请人： Lincoln University

发明人： Andriy Podolyan ,  David Rennison ,  Gregory Cook ,  Hong Jie Di ,  Keith Craig Cameron ,  Margaret Anne Brimble ,  Scott Ferguson ,  Robert Starr Ronimus ,  Vincenzo Carbone

IPC分类号： C05G3/90 ,  B09C1/08 ,  C02F1/68 ,  C05C3/00 ,  C05C9/00 ,  C07D237/14 ,  C07D239/34 ,  C07D241/18 ,  C02F103/20

摘要： Nitrification inhibitors and uses of same to prevent nitrate leaching or nitrous oxide emissions as well as increase pasture or crop production. The nitrification inhibitors and formulations including same may be used for direct or indirect application to soil or pasture.

公开(公告)号：US20210269829A1

公开(公告)日：2021-09-02

申请号：US17254725

申请日：2019-06-27

申请人： THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL ,  LINCOLN UNIVERSITY

发明人： Steven James Gray ,  David Palmer ,  Nadia Mitchell

IPC分类号： C12N15/86 ,  A61P25/28

摘要： This invention relates to polynucleotides comprising optimized CLNS open reading frame (ORF) sequences, vectors comprising the same, and methods of using the same for delivery of the ORF to a cell or a subject and to treat disorders associated with aberrant expression of a CLNS gene or aberrant activity of a CLNS gene product in the subject, such as CLNS disease.

公开(公告)号：US09434762B2

公开(公告)日：2016-09-06

申请号：US14206051

申请日：2014-03-12

申请人： Lincoln University ,  Canterprise Limited ,  Douglas Pharmaceuticals Limited

发明人： Andrew David Abell ,  James Morriss Coxon ,  Matthew Alan Jones ,  Stephen Brian McNabb ,  Axel Thomas Neffe ,  Steven Geoffrey Aitken ,  Blair Gibb Stuart ,  Janna Marie Nikkel ,  Joanna Kimberley Duncan ,  Mutita Klanchantra ,  James David Morton ,  Roy Bickerstaffe ,  Lucinda Jane Goodricke Robertson ,  Hannah Yun Young Lee ,  Matthew Stewart Muir

IPC分类号： C07K5/083 ,  C07K14/81

CPC分类号： C07K5/0808 ,  C07K14/8125

摘要： The present invention provides a novel class of macrocyclic compounds, which are useful as cysteine protease inhibitors. Also provided are novel intermediates and methods of preparing the compounds. The invention also provides pharmaceutical compositions comprising the compounds. The compounds and compositions are useful in methods of treating or preventing one or more diseases associated with cysteine protease activity, particularly those associated with calpain activity.

摘要翻译： 本发明提供了一类新的大环化合物，其可用作半胱氨酸蛋白酶抑制剂。 还提供了新的中间体和制备化合物的方法。 本发明还提供包含该化合物的药物组合物。 化合物和组合物可用于治疗或预防与半胱氨酸蛋白酶活性相关的一种或多种疾病，特别是与钙蛋白酶活性相关的疾病的方法。