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公开(公告)号：US10881774B2
公开(公告)日：2021-01-05
申请号：US15712764
申请日：2017-09-22
发明人： Andrew Halpert , Per Ulrich
摘要： A method to protect kidneys of a patient undergoing cardiac surgery patient including: administrating a diuretic to the patient to increase urine output of the patient during cardiac surgery, wherein the diuretic is administered during the cardiac surgery; anesthetizing the patient with a general anesthetic during the cardiac surgery; infusing an intravenous liquid into the patient during the cardiac surgery; monitoring a rate or amount of urine output of the patient during the cardiac surgery, and automatically adjusting a rate or amount of the intravenous liquid infused into the patient to achieve or exceed a target urine output during the cardiac surgery.
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公开(公告)号：US20180185577A9
公开(公告)日：2018-07-05
申请号：US14645730
申请日：2015-03-12
发明人： Andrew V. Halpert , Mark Tauscher , MARK GELFAND , HOWARD LEVIN
IPC分类号： A61M5/172
CPC分类号： A61M5/1723 , A61M2202/0496 , A61M2230/005
摘要： A fluid therapy method for an ADHF patient includes setting a urine output rate desired threshold, setting one or more desired negative net gain rates, and optionally setting a total fluid loss goal. The urine output of the patient is monitored and fluid is automatically administered to the patient at increasing rates to equal to or approximately match the patient's increasing urine output rates until the patient's urine output rate reaches the set urine output rate desired threshold. Thereafter, fluid is administered to the patient at rates to achieve the set desired negative net gain rate until the fluid loss goal is reached. Thereafter, until the end of therapy, fluid is administered to the patient at rates equal to or approximately equal to the monitored urine output rates.
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公开(公告)号：US07837667B2
公开(公告)日：2010-11-23
申请号：US11408391
申请日：2006-04-21
申请人： Mark Gelfand , Howard R. Levin
发明人： Mark Gelfand , Howard R. Levin
CPC分类号： A61M5/142 , A61B5/201 , A61B5/208 , A61B5/4839 , A61M5/007 , A61M5/16895 , A61M5/1723 , A61M5/365 , A61M2205/18 , A61M2205/3355 , A61M2205/3393 , G01G17/04
摘要： A patient hydration system and method wherein hydration fluid is administered to a patient and the patient's urine output is measured either by weight or some other suitable way. A controller is responsive to the patient's urine output measurement and configured to control the infusion rate to hydrate the patient based on the patient's urine output. The controller also detects abnormal patient urine output measurements and initiates corrective action in response.
摘要翻译： 一种患者水合系统和方法，其中向患者施用水合液，并且通过重量或一些其它合适的方式测量患者的尿量。 控制器响应于患者的尿量测量并且被配置为基于患者的尿液输出来控制输液速率以使患者水合。 控制器还可以检测出异常的患者尿量测量值，并作出响应启动纠正措施。
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4.发明授权Patient hydration system with a redundant monitoring of hydration fluid infusion 有权患者水合系统具有水化液输液的冗余监测公开(公告)号：US07758562B2
公开(公告)日：2010-07-20
申请号：US11408851
申请日：2006-04-21
申请人： Mark Gelfand , Howard R. Levin
发明人： Mark Gelfand , Howard R. Levin
CPC分类号： A61M5/1723 , A61B5/201 , A61B5/208 , A61B5/4839 , A61M5/007 , A61M5/142 , A61M5/16895 , A61M5/365 , A61M2205/18 , A61M2205/3355 , A61M2205/3393 , G01G17/04
摘要： A patient hydration system including an infusion device for administering hydration fluid to a patient, and a hydration fluid measurement device responsive to a source of hydration fluid, a patient urine output measurement device. A controller is responsive to the hydration fluid measurement device and the patient urine output measurement device. The controller operates the infusion device, in response to the patient urine output measurement device and the hydration fluid measurement device, to hydrate the patient based on the patient's urine output. The controller also monitors the operation history of the infusion device thereby providing redundancy in the measurement of the amount of hydration fluid administered to the patient.
摘要翻译： 一种患者水合系统，包括用于向患者施用水合流体的输注装置，以及响应于水合流体源的水合流体测量装置，患者尿液输出测量装置。 控制器响应于水合流体测量装置和患者尿液输出测量装置。 控制器响应于患者尿液输出测量装置和水合流体测量装置操作输液装置，以基于患者的尿液输出水合患者。 控制器还监测输注装置的操作历史，从而在测量给予患者的水合液量的量方面提供冗余。
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公开(公告)号：US07377916B2
公开(公告)日：2008-05-27
申请号：US10753693
申请日：2004-01-07
IPC分类号： A61B18/18
CPC分类号： A61B18/24 , A61B2017/00243 , A61B2017/22051 , A61B2017/22097
摘要： An endovascular tissue removal system including an expandable mechanism introduceable to the ventricular side of a valve to support the leaflets of the valve in a closed position and a tissue removal device advanceable to the leaflets and configured to resect the leaflets as they are supported by the expandable mechanism.
摘要翻译： 一种血管内组织去除系统，其包括可引导到瓣膜的心室侧的可扩张机构，以将瓣膜的小叶支撑在关闭位置，以及组织去除装置，其可推进到所述传单并且构造成在所述传播片支撑时可切除所述传单， 机制。
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公开(公告)号：US07204255B2
公开(公告)日：2007-04-17
申请号：US10628794
申请日：2003-07-28
IPC分类号： A61B19/00
CPC分类号： A61B18/24 , A61B2017/00243 , A61B2017/22069 , A61B2017/22097
摘要： An endovascular tissue removal device including a lumen with a distal steerable tip portion extending from a joint portion, registration means for holding the joint portion fixed in place in the vasculature, and a source of ablation energy in communication with the lumen whereby tissue can be resected by ablation energy as the tip portion is steered within the vasculature.
摘要翻译： 一种血管内组织去除装置，包括具有从关节部分延伸的远侧可操纵尖端部分的内腔，用于将固定在脉管系统中的适当位置的关节部分的定位装置和与内腔连通的消融能量源，从而可切除组织 通过消融能量作为尖端部分在脉管系统内转向。
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公开(公告)号：US6074384A
公开(公告)日：2000-06-13
申请号：US36503
申请日：1998-03-06
IPC分类号： A61B17/00 , A61B18/24 , A61B18/180
CPC分类号： A61B18/24 , A61B2017/00703
摘要： An apparatus for percutaneous laser revascularization of a patient's beating heart includes a laser system that produces a pulsed laser beam with a wavelength in a range of approximately 1.7 .mu.m to approximately 2.15 .mu.m, each pulse of the laser beam having a pulse duration in a range of approximately 1 ms and greater and having a pulse energy in a range of approximately 5 J to approximately 25 J. The pulse can include a train of micropulses. A fiber optic element that is coupled to the laser system is arranged with a catheter to pass through a vasculature of the patient and to deliver pulses of the laser beam to an interior wall of the patient's heart. The laser system can include a flash lamp-pumped laser in which a large capacitor bank discharges only a fraction of its stored energy through a flash lamp to fire the laser, wherein the capacitor discharge is turned off by a switchable device, such as a high current transistor, after the integrated energy of a laser pulse reaches a selected value. A pair of concave mirrors are arranged facing either end of the laser rod to form a resonant cavity, wherein each mirror has a curvature selected to compensate for changes in the index of refraction of the laser rod as a function of radius due to heating from the flash lamp. The laser system can be triggered to provide a laser pulse only during a refractive portion of the patient's heartbeat cycle. The apparatus is capable of forming a channel in the patient's heart to any desired depth by applying only a single laser pulse.
摘要翻译： 用于患者跳动心脏的经皮激光血管重建的装置包括产生波长在约1.7μm至约2.15μm范围内的脉冲激光束的激光系统，激光束的每个脉冲具有脉冲持续时间 大约1ms和更大的范围，并具有大约5J到大约25J的范围内的脉冲能量。脉冲可以包括一列微脉冲。 耦合到激光系统的光纤元件布置有导管以穿过患者的脉管系统并将激光束的脉冲输送到患者心脏的内壁。 激光系统可以包括闪光灯泵浦激光器，其中大电容器组仅通过闪光灯仅释放其存储能量的一部分以激发激光器，其中电容器放电由可切换装置例如高 在激光脉冲的积分能量达到选定值之后，电流晶体管。 一对凹面镜布置成面对激光棒的任一端以形成谐振腔，其中每个反射镜具有选择的曲率，以补偿激光棒的折射率的变化，作为半径的函数，由于来自 闪光灯。 激光系统可以被触发以仅在患者心跳周期的折射部分期间提供激光脉冲。 该装置能够通过仅施加单个激光脉冲在患者心脏中形成任何所需深度的通道。
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公开(公告)号：US5830210A
公开(公告)日：1998-11-03
申请号：US734135
申请日：1996-10-21
CPC分类号： A61N1/056 , A61B18/1492 , A61B18/1815 , A61B18/24 , A61B2017/00247 , A61B2018/00392 , A61B2018/2238
摘要： A catheter navigation apparatus includes a catheter system for percutaneous insertion into an internal organ cavity. The catheter system includes a treatment catheter and a navigation catheter; the navigation catheter includes a deployable framework at its distal end; the treatment catheter includes at least one conduit extending from its proximal to its distal end; the conduit having its distal end engaged with the framework; the navigation catheter includes a flexible link interconnecting the framework with a control mechanism at the proximal end of the navigation catheter for driving the link to deploy and retract the framework to guide the distal tip of the treatment catheter to target one or more selected positions on the inner wall of the organ cavity.
摘要翻译： 导管导航装置包括用于经皮插入内部器官腔的导管系统。 导管系统包括治疗导管和导航导管; 导航导管在其远端包括可展开的框架; 治疗导管包括从其近端延伸到其远端的至少一个导管; 导管的远端与框架接合; 导航导管包括将框架与导航导管的近端处的控制机构相互连接的柔性连杆，用于驱动连杆以展开和缩回框架，以引导治疗导管的远侧末端以对准位于 器官腔内壁。
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公开(公告)号：US09526833B2
公开(公告)日：2016-12-27
申请号：US12800673
申请日：2010-05-20
申请人： Mark Gelfand , Howard R. Levin
发明人： Mark Gelfand , Howard R. Levin
CPC分类号： A61M5/1723 , A61B5/201 , A61B5/208 , A61B5/4839 , A61M5/007 , A61M5/142 , A61M5/16895 , A61M5/365 , A61M2205/18 , A61M2205/3355 , A61M2205/3393 , G01G17/04
摘要： A patient hydration system including an infusion device for administering hydration fluid to a patient, and a hydration fluid measurement device responsive to a source of hydration fluid, a patient urine output measurement device. A controller is responsive to the hydration fluid measurement device and the patient urine output measurement device. The controller operates the infusion device, in response to the patient urine output measurement device and the hydration fluid measurement device, to hydrate the patient based on the patient's urine output. The controller also monitors the operation history of the infusion device thereby providing redundancy in the measurement of the amount of hydration fluid administered to the patient.
摘要翻译： 一种患者水合系统，包括用于向患者施用水合流体的输注装置，以及响应于水合流体源的水合流体测量装置，患者尿液输出测量装置。 控制器响应于水合流体测量装置和患者尿液输出测量装置。 控制器响应于患者尿液输出测量装置和水合流体测量装置操作输液装置，以基于患者的尿液输出水合患者。 控制器还监测输注装置的操作历史，从而在测量给予患者的水合液量的量方面提供冗余。
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公开(公告)号：US20150258277A1
公开(公告)日：2015-09-17
申请号：US14645730
申请日：2015-03-12
发明人： Andrew V. Halpert , Mark Tauscher
IPC分类号： A61M5/172
CPC分类号： A61M5/1723 , A61M2202/0496 , A61M2230/005
摘要： A fluid therapy method for an ADHF patient includes setting a urine output rate desired threshold, setting one or more desired negative net gain rates, and optionally setting a total fluid loss goal. The urine output of the patient is monitored and fluid is automatically administered to the patient at increasing rates to equal to or approximately match the patient's increasing urine output rates until the patient's urine output rate reaches the set urine output rate desired threshold. Thereafter, fluid is administered to the patient at rates to achieve the set desired negative net gain rate until the fluid loss goal is reached. Thereafter, until the end of therapy, fluid is administered to the patient at rates equal to or approximately equal to the monitored urine output rates.
摘要翻译： 用于ADHF患者的流体治疗方法包括设定尿液输出速率期望阈值，设定一个或多个期望的负净增加率，以及可选地设定总体损失目标。 监测患者的尿量，并以增加的速率将流体自动施用于患者等于或大致匹配患者增加的尿量，直到患者的尿量达到设定的尿液输出速率期望阈值为止。 此后，以达到设定的所需负净增益率的速率向患者施用流体，直到达到流体损失目标。 此后，在治疗结束之前，将流体以等于或近似等于所监测的尿液输出率的速率施用于患者。
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