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公开(公告)号:US4272536A
公开(公告)日:1981-06-09
申请号:US102674
申请日:1979-12-12
IPC分类号: A61K31/16 , A61K31/165 , A61K31/395 , A61P31/12 , A61P31/22 , C07C237/04 , C07C237/06 , C07D295/145 , C07D295/15 , C07C87/40 , C07C103/00
CPC分类号: C07D295/145 , C07C237/04 , C07C2101/14 , C07C2103/66
摘要: A compound having the formula ##STR1## wherein a is 0 or 1, R.sub.1 is hydrogen or lower alkyl, A is lower alkylene or lower alkylidene, and R.sub.2 and R.sub.3, which can be the same or different, are hydrogen, lower alkyl, cycloalkyl, benzyl or substituted benzyl, or ##STR2## form a saturated heterocyclic ring, and pharmacologically acceptable acid addition salt thereof, exhibits anti-viral activity and is free from significant effect on the central nervous system.
摘要翻译: 具有式“IMAGE”的化合物,其中a为0或1,R1为氢或低级烷基,A为低级亚烷基或低级亚烷基,R2和R3可相同或不同,为氢,低级烷基,环烷基 苄基或取代的苄基或“IMAGE”形成饱和杂环,并且其药理学上可接受的酸加成盐显示出抗病毒活性,对中枢神经系统没有显着影响。
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公开(公告)号:US4277473A
公开(公告)日:1981-07-07
申请号:US102702
申请日:1979-12-12
IPC分类号: A61K31/16 , A61K31/165 , A61K31/395 , A61P31/12 , C07C237/04 , C07C237/06 , C07D295/145 , C07D295/15 , C07C103/50 , C07C103/68
CPC分类号: C07D295/145 , C07C237/04 , C07C2101/14 , C07C2103/70
摘要: Compounds having the formula ##STR1## wherein a is 0 or 1, R.sub.1 is hydrogen or lower alkyl, A is lower alkylene or lower alkylidene, and R.sub.2 and R.sub.3, which can be the same or different, are hydrogen, lower alkyl, cycloalkyl, benzyl or substituted benzyl, or ##STR2## is a saturated heterocyclic ring, and acid addition salts thereof, possess anti-viral activity and reduced activity on the central nervous system.
摘要翻译: 具有式“IMAGE”的化合物,其中a为0或1,R 1为氢或低级烷基,A为低级亚烷基或低级亚烷基,R 2和R 3可相同或不同,为氢,低级烷基,环烷基, 苄基或取代的苄基,或
是饱和杂环,并且其酸加成盐具有抗中毒神经系统的抗病毒活性和降低的活性。 -
公开(公告)号:US4208252A
公开(公告)日:1980-06-17
申请号:US683153
申请日:1976-05-04
申请人: Masaaki Yoshida , Masao Watanabe , Kimio Tohma , Mitsuhiko Noda
发明人: Masaaki Yoshida , Masao Watanabe , Kimio Tohma , Mitsuhiko Noda
CPC分类号: C10B47/44 , C10B53/07 , Y02P20/143
摘要: An apparatus for treatment of rubber and plastic wastes, comprising in series an extruder for heating and melting rubber and plastic wastes to extrude the molten wastes, a decomposing section for heating the molten wastes to prepare decomposed products while optionally separating residues therefrom, a dry-distilling section for gasifying the decomposed products by dry-distillation, and a cooling section for cooling the dry-distilled products to separate gaseous materials from liquid materials.
摘要翻译: 一种用于处理橡胶和塑料废物的设备,包括用于加热和熔化橡胶和塑料废料以挤出熔融废物的挤出机,用于加热熔融废物以制备分解产物同时任选分离残余物的分解部分, 用于通过干馏气化分解产物的蒸馏部分,以及用于冷却干蒸馏产物以将液体材料与液体材料分离的冷却部分。
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公开(公告)号:US4248891A
公开(公告)日:1981-02-03
申请号:US102000
申请日:1979-12-07
IPC分类号: A61K31/13 , A61P31/12 , A61P31/22 , C07C49/323 , C07C61/135 , C07C67/00 , C07C209/00 , C07C211/19 , A61K31/205 , C07C87/40
CPC分类号: C07C61/135 , C07C211/19 , C07C49/323 , C07C2103/66 , Y10S514/934
摘要: Compounds having the formula ##STR1## in which R is lower alkyl, and acid addition salts of said compounds. The compounds possess anti-RNA-viral activity and also an antiviral activity against herpes virus.
摘要翻译: 具有式(I)的化合物,其中R是低级烷基,和所述化合物的酸加成盐。 该化合物具有抗RNA病毒活性,也具有针对疱疹病毒的抗病毒活性。
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