公开(公告)号：US08543195B1

公开(公告)日：2013-09-24

申请号：US13293632

申请日：2011-11-10

申请人： Brian Brockway ,  Marina Brockway

发明人： Brian Brockway ,  Marina Brockway

IPC分类号： A61B5/0402

CPC分类号： A61B5/7203 ,  A61B5/04017 ,  A61B5/0424 ,  A61B5/0428 ,  A61B5/04325 ,  A61B2560/045

摘要： Various embodiments are directed to signal processing. In accordance with example embodiments, methods and apparatuses involve using at least two electrodes that sense an ECG signal. A denoising module is communicatively coupled to the at least two electrodes, and receives the ECG signal sensed by the sensing electrodes. The denoising module includes circuitry that conditions and digitizes the ECG signal, and a computing circuit that processes the digitized ECG signal to denoise the ECG signal. A communications circuit generates a communication including the denoised ECG signal for access by a remote device.

摘要翻译： 各种实施例涉及信号处理。 根据示例性实施例，方法和装置包括使用感测ECG信号的至少两个电极。 去噪模块通信地耦合到至少两个电极，并且接收由感测电极感测的ECG信号。 去噪模块包括对ECG信号进行调节和数字化的电路，以及处理数字化ECG信号以去噪ECG信号的计算电路。 通信电路产生包括去噪的ECG信号以进行远程设备的通信。

公开(公告)号：US10231638B2

公开(公告)日：2019-03-19

申请号：US15237029

申请日：2016-08-15

申请人： VivaQuant LLC

发明人： Marina Brockway ,  Brian Brockway

IPC分类号： A61B5/0402 ,  A61B5/04 ,  A61B5/00 ,  A61B5/0408 ,  A61B5/0424 ,  A61B5/0428 ,  A61B5/0432 ,  A61B5/0404

摘要： Various embodiments are directed to signal processing. In accordance with example embodiments, methods and apparatuses involve using at least two electrodes that sense an ECG signal. A denoising module is communicatively coupled to the at least two electrodes, and receives the ECG signal sensed by the sensing electrodes. The denoising module includes circuitry that conditions and digitizes the ECG signal, and a computing circuit that processes the digitized ECG signal to denoise the ECG signal. A communications circuit generates a communication including the denoised ECG signal for access by a remote device.

公开(公告)号：US09492096B2

公开(公告)日：2016-11-15

申请号：US14467957

申请日：2014-08-25

申请人： VivaQuant LLC

发明人： Brian Brockway ,  Marina Brockway

IPC分类号： A61B5/04 ,  A61B5/0456 ,  A61B5/00 ,  A61B7/00 ,  A61B5/0245 ,  A61B5/0408 ,  A61B5/0452 ,  G06F17/14 ,  G06K9/00 ,  G06F19/00

CPC分类号： A61B5/04012 ,  A61B5/0006 ,  A61B5/0245 ,  A61B5/04017 ,  A61B5/04087 ,  A61B5/0452 ,  A61B5/0456 ,  A61B5/7253 ,  A61B7/00 ,  G06F17/14 ,  G06K9/0051 ,  G06K9/0053 ,  G16H50/30

摘要： Aspects of the present disclosure are directed to processing ECG signals from a subject. As may be implemented in accordance with one or more embodiments, respective electrodes sense ECG signals from a subject, and the ECG signals are digitized and processed, such as to remove noise, detect a QRS complex, evaluate quality, detect arrhythmia and/or to store the signals. In response to an input from the subject, one or more of the ECG signals is recorded along with sound from the user, such as to concurrently record the user's voice for describing conditions in connection with the recording of the ECG signals. This approach can be carried out in an enclosed housing, operated adjacent the subject's thorax. The processed digitized ECG signals and the audio signals are then communicated for receipt by an external device.

摘要翻译： 本公开的方面旨在处理来自对象的ECG信号。 如可以根据一个或多个实施例来实现的，各个电极感测来自对象的ECG信号，并且ECG信号被数字化和处理，诸如去除噪声，检测QRS复合物，评估质量，检测心律失常和/或 存储信号。 响应于来自主体的输入，一个或多个ECG信号与来自用户的声音一起被记录，例如同时记录用户的语音以便描述与ECG信号的记录有关的条件。 这种方法可以在封闭的房屋中进行，在受试者的胸部附近操作。 处理的数字化ECG信号和音频信号然后被传送以供外部设备接收。

公开(公告)号：US09408549B2

公开(公告)日：2016-08-09

申请号：US14818059

申请日：2015-08-04

申请人： VivaQuant LLC

发明人： Marina Brockway ,  Brian Brockway

IPC分类号： A61B5/00 ,  A61B5/0452 ,  A61B5/0205 ,  A61B5/0456

CPC分类号： A61B5/0452 ,  A61B5/0205 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/725 ,  A61B5/7257 ,  A61B5/726

摘要： Various aspects are directed to identifying a region of interest in a physiological signal. As may be consistent with one or more embodiments, the physiological signal is decomposed into subcomponents, and a subset of the subcomponents is selected based upon overlap of spectral energy with expected spectral energy of the region of interest, in at least one of the subcomponents. At least two of the subcomponents in the subset are combined and compared to a threshold, with the comparison being used to identify the location of the region of interest.

摘要翻译： 各个方面涉及识别生理信号中的感兴趣区域。 如同一个或多个实施例一样，生理信号被分解为子部件，并且基于光谱能量与感兴趣区域的预期光谱能量在至少一个子部件中的重叠来选择子部件的子集。 将子集中的至少两个子组件组合并与阈值进行比较，其中比较用于识别感兴趣区域的位置。

公开(公告)号：US09339202B2

公开(公告)日：2016-05-17

申请号：US13931228

申请日：2013-06-28

申请人： VivaQuant LLC

发明人： Marina Brockway ,  Brian Brockway

IPC分类号： A61B5/00 ,  A61B5/0402 ,  A61B5/0205 ,  A61B5/0456

CPC分类号： A61B5/7203 ,  A61B5/0002 ,  A61B5/0015 ,  A61B5/0205 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/04087 ,  A61B5/0456 ,  A61B5/6801 ,  G06F19/00

摘要： Physiological signals such as ECG signals are obtained from a patient. In accordance with one or more embodiments, an apparatus, system and/or method is directed to at least two ECG sensing electrodes that adhere to remote locations on a patient and sense ECG signals from the patient. An amplifier circuit amplifies the sensed ECG signals to provide amplified ECG signals, and a digitizing circuit digitizes the amplified ECG. A computing circuit processes the digitized ECG signals (e.g., by removing noise). A battery powers the aforesaid circuits, and a housing houses the battery and aforesaid circuit. A fastener mechanically fastens and electrically couples the housing to one of the electrodes, and the other electrodes are coupled to the amplifier via a flexible insulated lead wire.

摘要翻译： 从患者获得生理信号，如ECG信号。 根据一个或多个实施例，装置，系统和/或方法被引导到至少两个遵守患者的远程位置并且感测来自患者的ECG信号的ECG感测电极。 放大器电路放大所感测的ECG信号以提供放大的ECG信号，并且数字化电路将放大的ECG数字化。 计算电路处理数字化的ECG信号（例如，通过去除噪声）。 电池为上述电路供电，外壳容纳电池和上述电路。 紧固件机械地将壳体紧固并电耦合到电极中的一个，并且其它电极通过柔性绝缘导线耦合到放大器。

公开(公告)号：US08688202B2

公开(公告)日：2014-04-01

申请号：US13668898

申请日：2012-11-05

申请人： VivaQuant LLC

发明人： Marina Brockway ,  Brian Brockway ,  Robert Hamlin

IPC分类号： A61B5/04

CPC分类号： A61B5/04012 ,  A61B5/0452 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/7235 ,  A61B5/7253 ,  A61B7/00

摘要： A cardiac-based metric is computed based upon characteristics of a subject's cardiac function. In accordance with one or more embodiments, the end of a mechanical systole is identified for each of a plurality of cardiac cycles of a subject, based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle. The end of an electrical systole of an electrocardiogram (ECG) signal for each cardiac cycle is also identified. A cardiac-based metric is computed, based upon a time difference between the end of the electrical systole and the end of the mechanical systole, for the respective cardiac cycles.

摘要翻译： 基于心脏的度量是基于受试者心脏功能的特征来计算的。 根据一个或多个实施例，基于与心动周期期间主动脉瓣闭合相关的声学振动，识别针对受试者的多个心动周期中的每一个的机械收缩末端。 也确定了每个心动周期的心电图（ECG）信号的电收缩端的结束。 基于心脏周期的电收缩末端与机械收缩末之间的时间差计算心脏度量。

公开(公告)号：US09414786B1

公开(公告)日：2016-08-16

申请号：US14032544

申请日：2013-09-20

申请人： VivaQuant LLC

发明人： Marina Brockway ,  Brian Brockway

IPC分类号： A61B5/0402 ,  A61B5/00 ,  A61B5/04 ,  A61B5/0408

CPC分类号： A61B5/04012 ,  A61B5/0006 ,  A61B5/0026 ,  A61B5/04017 ,  A61B5/0402 ,  A61B5/0404 ,  A61B5/04087 ,  A61B5/0424 ,  A61B5/0428 ,  A61B5/04325 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7253 ,  A61B2560/0219 ,  A61B2560/045

摘要： Various embodiments are directed to signal processing. In accordance with example embodiments, methods and apparatuses involve using at least two electrodes that sense an ECG signal. A denoising module is communicatively coupled to the at least two electrodes, and receives the ECG signal sensed by the sensing electrodes. The denoising module includes circuitry that conditions and digitizes the ECG signal, and a computing circuit that processes the digitized ECG signal to denoise the ECG signal. A communications circuit generates a communication including the denoised ECG signal for access by a remote device.

公开(公告)号：US09414758B1

公开(公告)日：2016-08-16

申请号：US13349314

申请日：2012-01-12

申请人： Brian Brockway ,  Marina Brockway ,  Anna M. Brockway

发明人： Brian Brockway ,  Marina Brockway ,  Anna M. Brockway

IPC分类号： A61B5/0408 ,  A61B5/00

CPC分类号： A61B5/0408 ,  A61B5/04017 ,  A61B5/0428 ,  A61B5/6801 ,  A61B5/6804 ,  A61B5/725 ,  A61B5/7253 ,  A61B5/726 ,  A61B2562/0209 ,  A61B2562/0285

摘要： Monitoring of physiological signals is effected. In accordance with one or more embodiments, an apparatus, system and/or method is directed to sensing physiological signals such as ECG signals. A skin-contacting electrode apparatus includes an electrically conductive sheet having a conductive surface configured and arranged to contact a subject's skin, and conductive flexible microfibers extending from the conductive surface and configured and arranged to protrude into skin pores and sense an ECG signal.

摘要翻译： 监测生理信号。 根据一个或多个实施例，装置，系统和/或方法被引导以感测例如ECG信号的生理信号。 皮肤接触电极装置包括具有导电表面的导电片，导电表面构造和布置成接触受试者的皮肤，以及导电的柔性微纤维，其从导电表面延伸并且被配置和布置成突出到皮肤孔中并感测ECG信号。

公开(公告)号：US08632465B1

公开(公告)日：2014-01-21

申请号：US12938995

申请日：2010-11-03

申请人： Marina Brockway

发明人： Marina Brockway

IPC分类号： A61N5/02

CPC分类号： H03H17/0248 ,  A61B5/04017 ,  A61B5/0452 ,  A61B5/7253 ,  G06F17/14 ,  G06K9/0051 ,  G06K9/0053

摘要： Physiological signals are denoised. In accordance with an example embodiment, a denoised physiological signal is generated from an input signal including a desired physiological signal and noise. The input signal is decomposed from a first domain into subcomponents in a second domain of higher dimension than the first domain. Target subcomponents of the input signal that are associated with the desired physiological signal are identified, based upon the spatial distribution of the subcomponents. A denoised physiological signal is constructed in the first domain from at least one of the identified target subcomponents.

摘要翻译： 生理信号被去噪。 根据示例性实施例，从包括期望的生理信号和噪声的输入信号产生去噪生理信号。 输入信号从第一域分解成比第一域更高维度的第二域的子部件。 基于子部件的空间分布来识别与期望的生理信号相关联的输入信号的目标子部件。 从至少一个所识别的目标子组件在第一域中构建去噪的生理信号。

公开(公告)号：US20130131530A1

公开(公告)日：2013-05-23

申请号：US13668898

申请日：2012-11-05

申请人： VivaQuant LLC

发明人： MARINA BROCKWAY ,  BRIAN BROCKWAY ,  ROBERT HAMLIN

IPC分类号： A61B5/04 ,  A61B7/00 ,  A61B5/0456 ,  A61B5/0452

CPC分类号： A61B5/04012 ,  A61B5/0452 ,  A61B5/0456 ,  A61B5/7203 ,  A61B5/7235 ,  A61B5/7253 ,  A61B7/00

摘要： A cardiac-based metric is computed based upon characteristics of a subject's cardiac function. In accordance with one or more embodiments, the end of a mechanical systole is identified for each of a plurality of cardiac cycles of a subject, based upon an acoustical vibration associated with closure of an aortic valve during the cardiac cycle. The end of an electrical systole of an electrocardiogram (ECG) signal for each cardiac cycle is also identified. A cardiac-based metric is computed, based upon a time difference between the end of the electrical systole and the end of the mechanical systole, for the respective cardiac cycles.

摘要翻译： 基于心脏的度量是基于受试者心脏功能的特征来计算的。 根据一个或多个实施例，基于与心动周期期间主动脉瓣闭合相关的声学振动，识别针对受试者的多个心动周期中的每一个的机械收缩末端。 也确定了每个心动周期的心电图（ECG）信号的电收缩端的结束。 基于心脏周期的电收缩末端与机械收缩末之间的时间差计算心脏度量。