Particle sensor with interferent discrimination

    公开(公告)号:US10054532B2

    公开(公告)日:2018-08-21

    申请号:US15679465

    申请日:2017-08-17

    申请人: BugLab LLC

    IPC分类号: G01N15/06 G01N21/51 C12M1/34

    摘要: This invention provides methods and devices to measure particle suspension concentrations in the presence of potential interferents. Particle back-scatter readings are taken at light wavelengths that are absorbed by the medium before interacting with surrounding objects. Source-detector spacings are minimized compared to the mean absorbance path length of light, thereby maximizing the range of sensitivity to particle concentration. Discrimination against potentially interfering particles, such as bubbles, is provided by mapping the signal distribution against the central signal value and/or by the use of statistical measures with reduced dependence on outliers. The methods and devices allow accurate particle concentration readings over a wide range of concentration in environments crowded with potentially interfering objects and in the presence of variable concentrations and sizes of potentially interfering particles.

    Holographic computer system
    3.
    发明授权

    公开(公告)号:US10755192B2

    公开(公告)日:2020-08-25

    申请号:US15724796

    申请日:2017-10-04

    IPC分类号: G06N10/00 B82Y10/00 G06E3/00

    摘要: A method and apparatus used for general purpose problem solving using entanglement properties of holography. Intelligent point-based entities having spatial and other electromagnetic properties called DROPLETS [Data-Representative-Object-Particle(s)-Liking-EnTanglement] are generated as avatars, or delegate objects, connected to concrete or abstract data sources representing a situation, event or other problem. Each DROPLET's properties are controlled by changes in the input sources, feedback, changes in itself, and/or changes of other DROPLETS. Coherent rays are introduced and interact with said DROPLETS, generating an INTELLIGENCE WAVEFRONT. Interference patterns are recorded and converted to binary machine codes used as instruction keys to store and lock human readable and/or machine readable content components into a plurality of associative memories. Said content includes waveforms, harmonics, codes, data, and other holograms. Upon recognition of future like-patterns of situations, events and other problems, the appropriate content components, which are dispersed and stored wholistically throughout the system using spread spectrum techniques, are rapidly unlocked, retrieved and presented as solutions or partial solutions. Hardware, software, and hybrid hardware and software embodiments are envisioned.In conclusion, to the inventors' knowledge, there is no precedent in the prior art that is capable of analyzing or solving problems of wide latitude of complexity using the least understood, least recognized, enfoldment properties of the science of holography. In the case of the Holographic Computer System, this enfoldment, or quantum-like entanglement, is made to serve as a practical and effective general purpose problem solving tool.Although the foregoing description contains many specifics, these are not to be construed as limiting the scope of the present invention, but merely as providing certain exemplary embodiments. Similarly, other embodiments of the invention may be devised which do not depart from the spirit or scope of the present invention. The scope of the invention is, therefore, indicated and limited only by the appended claims and their legal equivalents, rather than by the foregoing description. All additions, deletions, and modifications to the invention, as disclosed herein, which fall within the meaning and scope of the claims are encompassed by the present invention.

    Assay
    4.
    发明授权
    Assay 有权

    公开(公告)号:US10267801B2

    公开(公告)日:2019-04-23

    申请号:US14489207

    申请日:2014-09-17

    IPC分类号: G01N33/68 G01N33/574

    摘要: This disclosure relates to a diagnostic/prognostic assay for prostate cancer and including kits used in said assay.

    Diagnostic method
    8.
    发明授权

    公开(公告)号:US10107814B2

    公开(公告)日:2018-10-23

    申请号:US13512585

    申请日:2012-01-06

    IPC分类号: G01N33/53 G01N33/574

    摘要: The invention provides a method of detecting a subject suffering from, or at risk of suffering from, bladder cancer the method comprising i) providing a body fluid sample isolated from a subject; ii) isolating cells from said sample to provide a cell sample; iii) contacting the sample with a specific binding member capable of binding to a minichromosome maintenance (MCM) polypeptide(s); iv) determining the binding of said specific binding member to the cell sample; v) counting those cells in said cell sample which bound to said specific binding member to provide a cell count; vi) determining, based on the cell count, whether the subject has, or is at risk of having, bladder cancer.