公开(公告)号：US07435850B2

公开(公告)日：2008-10-14

申请号：US11824392

申请日：2007-06-29

Applicant: Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

Inventor： Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

IPC: C07C233/00 ,  C07C235/00 ,  C07C237/00 ,  C07C239/00

CPC classification number: C07C233/18

Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.

公开(公告)号：US20080004349A1

公开(公告)日：2008-01-03

申请号：US11823771

申请日：2007-06-28

Applicant: Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

Inventor： Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

IPC: A61K31/165 ,  A61P25/00 ,  C07C233/17

CPC classification number: C07C233/18

Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.

公开(公告)号：US20100137446A1

公开(公告)日：2010-06-03

申请号：US12452456

申请日：2008-07-01

Applicant: Said Yous ,  Mohamed Ettaoussi ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

Inventor： Said Yous ,  Mohamed Ettaoussi ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

IPC: A61K31/165 ,  C07C233/16 ,  A61P25/00 ,  A61P25/22 ,  A61P25/24 ,  A61P25/28

CPC classification number: C07C233/18 ,  C07C233/60 ,  C07C2601/02 ,  C07C2601/04

Abstract: Compounds of formula (I): wherein: R1 represents alkyl, alkenyl, haloalkyl, polyhaloalkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, R2 represents a fluorine atom or an alkyl group substituted by one or more fluorine atoms. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.

Abstract translation: 式（I）化合物：其中：R 1表示烷基，烯基，卤代烷基，多卤代烷基，环烷基，环烷基烷基，芳基，芳基烷基，杂芳基或杂芳基烷基，R 2表示氟原子或被一个或多个氟原子取代的烷基。 含有该药物的药物可用于治疗褪黑激素系统的疾病。

公开(公告)号：US20080004348A1

公开(公告)日：2008-01-03

申请号：US11823130

申请日：2007-06-27

Applicant: Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Matthieu Desroses ,  Jean-Albert Boutin ,  Valerie Audinot

Inventor： Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Matthieu Desroses ,  Jean-Albert Boutin ,  Valerie Audinot

IPC: A61K31/16 ,  C07C235/32

CPC classification number: C07C233/60 ,  C07C233/18 ,  C07C233/20 ,  C07C233/78 ,  C07C247/10 ,  C07C275/24 ,  C07C309/66 ,  C07C311/05 ,  C07C2601/02 ,  C07C2601/04 ,  C07D295/125 ,  C07D295/15

Abstract: A compound selected from those of formula (I): wherein: R1 represents a group R4 or NHR4, wherein R4 is as defined in the description; R2 represents a substituted linear or branched (C1-C6)alkyl group; R3 represents a hydrogen or halogen atom or a linear or branched (C1-C6)alkyl or linear or branched (C2-C6)alkenyl group. Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.

Abstract translation: 选自式（I）的化合物的化合物：其中：R 1表示基团R 4或NHR 4，其中R 1， 4 如说明书中所定义; R 2表示取代的直链或支链（C 1 -C 6 -C 6）烷基; R 3表示氢或卤素原子或直链或支链（C 1 -C 6 -C 6）烷基或直链或支链（C _{2个C 6个C 6链烯基。 含有该药物的药物可用于治疗褪黑激素系统的病症。}

公开(公告)号：US07947852B2

公开(公告)日：2011-05-24

申请号：US12452429

申请日：2008-07-01

Applicant: Said Yous ,  Mohamed Ettaoussi ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

Inventor： Said Yous ,  Mohamed Ettaoussi ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

IPC: C07C233/233 ,  A61K31/16

CPC classification number: C07C251/48

Abstract: Compounds of formula (I): wherein: R1 represents alkyl, alkenyl, haloalkyl, polyhaloalkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, X represents a group N—OR2 wherein R2 represents a hydrogen atom or an alkyl group. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.

Abstract translation: 式（I）的化合物：其中：R 1表示烷基，烯基，卤代烷基，多卤代烷基，环烷基，环烷基烷基，芳基，芳烷基，杂芳基或杂芳基烷基，X表示基团N-OR 2，其中R 2表示氢原子或烷基。 含有该药物的药物可用于治疗褪黑激素系统的疾病。

公开(公告)号：US20100168244A1

公开(公告)日：2010-07-01

申请号：US12452429

申请日：2008-07-01

Applicant: Said Yous ,  Mohamed Ettaoussi ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

Inventor： Said Yous ,  Mohamed Ettaoussi ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

IPC: A61K31/16 ,  C07C233/02 ,  A61P25/00 ,  A61P25/28 ,  A61P25/18 ,  A61P9/00 ,  A61P25/24 ,  A61P3/10 ,  A61P35/04 ,  A61P37/00 ,  A61P15/00 ,  A61P25/06

CPC classification number: C07C251/48

Abstract: Compounds of formula (I): wherein: R1 represents alkyl, alkenyl, haloalkyl, polyhaloalkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heteroaryl or heteroarylalkyl, X represents a group N—OR2 wherein R2 represents a hydrogen atom or an alkyl group. Medicinal products containing the same which are useful in treating disorders of the melatoninergic system.

Abstract translation: 式（I）的化合物：其中：R 1表示烷基，烯基，卤代烷基，多卤代烷基，环烷基，环烷基烷基，芳基，芳烷基，杂芳基或杂芳基烷基，X表示基团N-OR 2，其中R 2表示氢原子或烷基。 含有该药物的药物可用于治疗褪黑激素系统的疾病。

公开(公告)号：US07462741B2

公开(公告)日：2008-12-09

申请号：US11823771

申请日：2007-06-28

Applicant: Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

Inventor： Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

IPC: C07C233/17 ,  A61K31/165

CPC classification number: C07C233/18

Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.

Abstract translation: 选自式（I）的化合物：含有该化合物的药物，其可用于治疗褪黑激素系统的病症。

公开(公告)号：US20080004350A1

公开(公告)日：2008-01-03

申请号：US11824392

申请日：2007-06-29

Applicant: Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

Inventor： Said Yous ,  Basile Peres ,  Ahmed Sabaouni ,  Pascal Berthelot ,  Michael Spedding ,  Philippe Delagrange ,  Daniel-Henri Caignard ,  Mark Millan

IPC: A61K31/16 ,  C07C235/32

CPC classification number: C07C233/18

Abstract: A compound selected from those of formula (I): Medicinal products containing the same which are useful in the treatment of disorders of the melatoninergic system.