公开(公告)号：US5263982A

公开(公告)日：1993-11-23

申请号：US668562

申请日：1991-03-13

申请人： Yasushi Shimomura ,  Masahiko Yamaguchi ,  Akio Funakubo

发明人： Yasushi Shimomura ,  Masahiko Yamaguchi ,  Akio Funakubo

IPC分类号： A61M1/16 ,  B01D63/02 ,  B01D63/04 ,  A61F2/04 ,  A61M37/00

CPC分类号： A61M1/1698 ,  A61M1/1625 ,  B01D63/02 ,  B01D63/021 ,  B01D63/04 ,  B01D2313/08

摘要： The hollow fiber membrane type ariticial lung has an inner cylinder, an outer cylinder, a hollow fiber bundle formed by collecting porous hollow fiber membrane and a supporting member for liquid-hermetically supporting the outer surface of the inner cylinder, the inner surface of the outer cylinder and the outer surface of the hollow fiber membrane at the two ends of the inner cylinder, the outer cylinder and the hollow fiber bundle in such a manner that the hollow fiber membrane is opened. The arificial lung reveals a reduced pressure loss and is capable of preventing blood channeling, and exhibit an excellent gas exchanging efficiency.

公开(公告)号：US5308314A

公开(公告)日：1994-05-03

申请号：US944086

申请日：1992-09-11

申请人： Yasuhiro Fukui ,  Akio Funakubo ,  Katsumi Takahashi ,  Hiroshi Sasagawa ,  Hikaru Nakanishi

发明人： Yasuhiro Fukui ,  Akio Funakubo ,  Katsumi Takahashi ,  Hiroshi Sasagawa ,  Hikaru Nakanishi

IPC分类号： A61M1/14 ,  A61M1/10 ,  A61M1/16 ,  A61M1/36 ,  A61M37/00

CPC分类号： A61M1/1698 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/1036 ,  A61M1/1625 ,  A61M1/1629 ,  A61M1/3663 ,  A61M2205/3666 ,  Y10S128/03 ,  Y10S415/90

摘要： An integrated heart-lung machine, which includes a blood pump having a casing of a cup-like shape interiorly defining a pump chamber at an intermediate portion thereof for pumping in and out blood from a blood inlet to a guide flange formed at opposite ends of the casing; a rotor having a rotary member securely fixed to the fore end thereof within the pump chamber and journalled in the guide flange; an artificial lung of a doughnut-like or cylindrical shape connected contiguously to a blood flow passage in the guide flange and concentrically with the rotor; a stator detachably fitted in an intermediate portion between the rotor and the artificial lung; and a pedestal base located at one side of the artificial lung and provided with a blood outlet in communication with the artificial lung. Accordingly, influent blood to the pump chamber is sent into the artificial lung through the blood passage by the pumping action of the rotor, and is refreshed by contact with air or oxygen in the lung, which is maintained in a heated state by the stator, and returned to the patient's body through the blood outlet. This arrangement permits minimizing of the length of the blood circulating passages to and through the machine and permits shortening and minimizing of the blood passages interconnecting the blood pump, artificial lung and blood filter, while preventing blood contamination and leaks as well as blood cell destruction. Easy installation and handling is also permitted in a sanitary region on a bed or on an operating table.

摘要翻译： 一种综合的心肺机器，其包括具有杯状形状的壳体的血泵，其内部限定在其中间部分处的泵室，用于将血液从血液入口泵入和输出到形成在相对端的引导凸缘 套管 转子，其具有在泵室内牢固地固定到其前端的旋转构件，并且轴颈安装在引导凸缘中; 环形或圆柱形的人造肺与引导凸缘中的血流通道连续并与转子同心连接; 可拆卸地安装在转子和人造肺之间的中间部分的定子; 以及位于人造肺的一侧的基座，并具有与人造肺连通的血液出口。 因此，通过转子的泵送作用将流入泵室的血液通过血液通道送入人造肺，并且通过与定子保持在加热状态的肺中的空气或氧气接触而被刷新， 并通过出血口返回病人的身体。 这种布置允许使通过机器的血液循环通道的长度最小化，并且允许缩短和最小化血液通道，连接血液泵，人造肺和血液过滤器，同时防止血液污染和泄漏以及血细胞破坏。 在床上或手术台上的卫生区域也允许安装和处理方便。

公开(公告)号：US5855201A

公开(公告)日：1999-01-05

申请号：US720052

申请日：1996-09-27

申请人： Yasuhiro Fukui ,  Akio Funakubo ,  Koshiro Sato ,  Masanori Katayama

发明人： Yasuhiro Fukui ,  Akio Funakubo ,  Koshiro Sato ,  Masanori Katayama

IPC分类号： A61M1/18 ,  A61M1/16 ,  B01D53/22 ,  B01D63/02 ,  B01D69/08 ,  B01D71/70 ,  A61M15/00 ,  A61M1/14 ,  A61M16/00 ,  B01D63/00

CPC分类号： B01D71/70 ,  B01D53/22 ,  B01D63/02 ,  B01D63/027 ,  B01D69/08 ,  A61M1/1698 ,  B01D2313/20

摘要： Disclosed is a small-sized gas exchange apparatus of high performance having an increased gas exchange rate and a reduced priming volume, comprising a hollow fiber module M.sub.1 formed by bundling a plurality of silicone membrane hollow fibers 1 wound in the form of a twilled pattern, a housing H.sub.1 for enclosing the hollow fiber module, an internal perfusion passage and an external perfusion passage formed within the housing H.sub.1, a first inlet A and a first outlet B formed on the housing for gas or liquid for communication with the internal perfusion passage, and a second inlet C and a second outlet D formed on the housing for gas or liquid for communication with the external perfusion passage.

摘要翻译： 公开了一种具有增加的气体交换速率和降低的起动容积的高性能的小型气体交换装置，包括通过将多个以斜纹图案形式缠绕的硅氧烷膜中空纤维1形成的中空纤维模块M1， 用于封闭中空纤维模块的壳体H1，形成在壳体H1内部的内部灌注通道和外部灌注通道，形成在用于气体或液体的壳体上的用于与内部灌注通道连通的第一入口A和第一出口B， 以及形成在壳体上的用于与外部灌注通道连通的气体或液体的第二入口C和第二出口D.