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    Corneal Inlay Design and Methods of Correcting Vision
    1.
    发明申请
    Corneal Inlay Design and Methods of Correcting Vision 有权
    角膜镶嵌设计和矫正视力的方法

    公开(公告)号：US20090198325A1

    公开(公告)日：2009-08-06

    申请号：US12418325

    申请日：2009-04-03

    Applicant: Keith Holliday ,  Alan Lang

    Inventor： Keith Holliday ,  Alan Lang

    IPC: A61F9/008 ,  A61F2/14

    CPC classification number: A61F9/00812 ,  A61F2/145 ,  A61F2/1451 ,  A61F2/147 ,  A61F2009/00872

    Abstract: Methods of designing corneal implants, such as inlays, to compensate for a corneal response, such as epithelial remodeling of the epithelial layer, to the presence of the implant. Additionally, methods of performing alternative corneal vision correction procedures to compensate for an epithelial response to the procedure. Methods of compensating for a corneal response when performing a vision correction procedure to create a center near region of the cornea for near vision while providing distance vision peripheral to the central near zone.

    Abstract translation: 设计角膜植入物（例如嵌体）以补偿角膜反应（例如上皮层的上皮重构）到植入物的存在的方法。 另外，执行替代性角膜视力矫正程序以补偿对该过程的上皮反应的方法。 补偿角膜反应的方法，当进行视力矫正程序以在靠近视力的角膜附近创建一个中心附近区域时，同时为中心近区域提供距离视野。

    OPHTHALMIC DEVICES HAVING A HIGHLY SELECTIVE VIOLET LIGHT TRANSMISSIVE FILTER AND RELATED METHODS
    2.
    发明申请
    OPHTHALMIC DEVICES HAVING A HIGHLY SELECTIVE VIOLET LIGHT TRANSMISSIVE FILTER AND RELATED METHODS 审中-公开
    具有高选择性紫外线透射滤光片的相关方法及相关方法

    公开(公告)号：US20080013045A1

    公开(公告)日：2008-01-17

    申请号：US11851560

    申请日：2007-09-07

    Applicant: Martin Mainster ,  Alan Lang ,  Michael Lowery

    Inventor： Martin Mainster ,  Alan Lang ,  Michael Lowery

    IPC: G02C7/10

    CPC classification number: G02C7/108 ,  A61F2/1659

    Abstract: Ophthalmic devices are provided having a violet-light vertical cut-off filter abruptly absorbs light between the wave lengths of between approximately and 400 nm and 450 nm such that a curve when plotted as percent transmission versus wavelength has the shape as depicted in FIG. 2. In one embodiment the ophthalmic devices are made from acrylates and the light absorbing compound is an Eastman Yellow 035 MA dye.

    Abstract translation: 提供具有紫光垂直截止滤光片的眼科装置在约400nm至450nm之间的波长之间突然吸收光，使得当透射率相对于波长的百分比绘制时的曲线具有如图3所示的形状。 2。 在一个实施方案中，眼科装置由丙烯酸酯制成，并且光吸收化合物是伊斯曼黄035MA染料。

    Ophthalmic devices having a highly selective violet light transmissive filter and related methods
    4.
    发明申请
    Ophthalmic devices having a highly selective violet light transmissive filter and related methods 有权
    具有高选择性紫光透射滤光片的眼科装置及相关方法

    公开(公告)号：US20050243272A1

    公开(公告)日：2005-11-03

    申请号：US11115743

    申请日：2005-04-26

    Applicant: Martin Mainster ,  Alan Lang ,  Michael Lowery

    Inventor： Martin Mainster ,  Alan Lang ,  Michael Lowery

    IPC: G02C7/04 ,  G02C7/10

    CPC classification number: G02C7/108 ,  A61F2/1659

    Abstract: Ophthalmic devices are provided having a violet-light vertical cut-off filter abruptly absorbs light between the wave lengths of between approximately and 400 nm and 450 nm such that a curve when plotted as percent transmission versus wavelength has the shape as depicted in FIG. 2. In one embodiment the ophthalmic devices are made from acrylates and the light absorbing compound is an Eastman Yellow 035 MA dye.

    Abstract translation: 提供具有紫光垂直截止滤光片的眼科装置在约400nm至450nm之间的波长之间突然吸收光，使得当透射率相对于波长的百分比绘制时的曲线具有如图3所示的形状。 在一个实施方案中，眼用装置由丙烯酸酯制成，光吸收化合物是Eastman Yellow 035MA染料。

    Par-2-activating peptide derivative and pharmaceutical composition using the same
    6.
    发明授权
    Par-2-activating peptide derivative and pharmaceutical composition using the same 失效
    对二激活肽衍生物和使用其的药物组合物

    公开(公告)号：US07541339B2

    公开(公告)日：2009-06-02

    申请号：US10517803

    申请日：2003-06-10

    Applicant: Robert Ramage ,  Robin Plevin ,  Kevin Thomas Shaw ,  Lu Jiang ,  Louise Claire Young ,  Alan Lang Harvey ,  Pu Wang ,  Toru Kanke ,  Junichi Kawagoe ,  Mototsugu Kabeya

    Inventor： Robert Ramage ,  Robin Plevin ,  Kevin Thomas Shaw ,  Lu Jiang ,  Louise Claire Young ,  Alan Lang Harvey ,  Pu Wang ,  Toru Kanke ,  Junichi Kawagoe ,  Mototsugu Kabeya

    IPC: A61K38/08 ,  C07K7/06

    CPC classification number: C07K14/705 ,  A61K38/00 ,  C07K7/06

    Abstract: The present invention relates to a peptide derivative represented by the general formula (I) or a salt thereof: Z-(CH2)n—CO—NH-Leu-Ile-Gly-AA1-AA2-CO—R (I) wherein Z represents an aryl group which may or may not have a substituent or a heteroaryl group which may or may not have a substituent; n represents 0, 1 or 2: AA1-AA2 represents Lys-Val or Arg-Leu; and R represents —OH or —NH2, and relates to a pharmaceutical composition comprising a peptide derivative represented by the general formula (I) or a salt thereof, and a pharmaceutically acceptable carrier thereof. The peptide derivative is useful as a prophylactic and therapeutic agent of dysfunction of masticatory, dysphagia, dysgeusia, ozostomia, intra-oral cavity dysphoria, intra-oral cavity infections, intra-oral cavity inflammations, dry eye, ectocornea detachment, keratitis, corneal ulcer, conjunctivitis, stomach ulcer, duodenal ulcer, gastritis, diarrhea, enteritis or Sjogren's syndrome.

    Abstract translation: 本发明涉及由通式（I）表示的肽衍生物或其盐：Z-（CH2）n-CO-NH-Leu-Ile-Gly-AA1-AA2-CO-R（Ⅰ）其中Z 表示可以具有也可以不具有取代基的芳基或可以具有取代基的杂芳基; n表示0,1或2：AA1-AA2表示Lys-Val或Arg-Leu; 和R表示-OH或-NH 2，并且涉及包含由通式（I）表示的肽衍生物或其盐及其药学上可接受的载体的药物组合物。 肽衍生物可用作咀嚼，吞咽困难，发重症，口臭，口腔内烦躁，口腔内感染，口腔内炎症，干眼症，异位角脱落，角膜炎，角膜溃疡功能障碍的预防和治疗剂 ，结膜炎，胃溃疡，十二指肠溃疡，胃炎，腹泻，肠炎或干燥综合征。

    Intracorneal inlays
    7.
    发明申请
    Intracorneal inlays 审中-公开
    胸膜内嵌

    公开(公告)号：US20070129797A1

    公开(公告)日：2007-06-07

    申请号：US11293644

    申请日：2005-12-01

    Applicant: Alan Lang ,  Troy Miller

    Inventor： Alan Lang ,  Troy Miller

    IPC: A61F2/14

    CPC classification number: A61F2/145 ,  A61B3/107 ,  A61F2/147

    Abstract: Described herein are designs of intracorneal inlays to produce desired shapes of the cornea's anterior surface for correcting vision impairments. In an exemplarily embodiment, a thickness profile is defined by a difference between a desired post-operative anterior corneal surface that corrects a patient's vision impairment and the patient's pre-operative anterior corneal surface. An inlay is then dimensioned to substantially have the same thickness profile. When implanted in the patient's cornea, the thickness profile of the inlay is substantially transferred to the anterior corneal surface through the intervening corneal tissue, thereby producing the desired post-operative anterior corneal surface.

    Abstract translation: 这里描述了用于产生角膜前表面的用于矫正视力障碍的所需形状的角内嵌入物的设计。 在示例性实施例中，厚度分布由矫正患者视力障碍的期望的术后前角膜表面与患者的术前前角膜表面之间的差定义。 然后将嵌体尺寸设定为基本上具有相同的厚度分布。 当植入患者的角膜时，嵌体的厚度分布通过介入的角膜组织基本上转移到前角膜表面，从而产生所需的术后前角膜表面。

    Convertible support
    9.
    发明授权
    Convertible support 有权
    可转换支持

    公开(公告)号：US07047716B2

    公开(公告)日：2006-05-23

    申请号：US10375976

    申请日：2003-02-28

    Applicant: Derek Alan Lang

    Inventor： Derek Alan Lang

    IPC: A01F34/63

    CPC classification number: A01D34/82 ,  A01D34/001 ,  A01D2101/00

    Abstract: A mower including support for an operator in a standing position during use thereof. Specifically, the mower includes a support against which an operator may lean when operating the mower in the standing position. Additionally, the support includes a portion capable of being straddled and then sat upon by the operator. This capability allows the operator to relieve at least some of the pressure applied to his/her body during extended periods of standing on the platform.

    Abstract translation: 一种割草机，包括在使用期间对处于站立位置的操作者的支撑。 具体地，割草机包括当在停放位置操作割草机时操作者可以倾斜的支撑件。 此外，支撑件包括能够跨接并随后由操作者坐下的部分。 这种能力允许操作者在平台上长时间站立时，至少减轻施加到他/她身上的一些压力。

    Ophthalmic lens with multiple phase plates
    10.
    发明申请
    Ophthalmic lens with multiple phase plates 有权
    具有多相板的眼科镜片

    公开(公告)号：US20060098163A1

    公开(公告)日：2006-05-11

    申请号：US11259524

    申请日：2005-10-25

    Applicant: Mark Bandhauer ,  Alan Lang

    Inventor： Mark Bandhauer ,  Alan Lang

    IPC: G02C7/04

    CPC classification number: A61F2/1613 ,  A61F2/1618 ,  A61F2/1654 ,  G02C7/06

    Abstract: An ophthalmic lens for providing a plurality of foci has an optic comprising an anterior surface, a posterior surface, and an optical axis. The optic has a first region and a second region. The first region has a refractive optical power and comprises a multifocal phase plate for forming a first focus and a second focus. The second region has a refractive optical power and comprises a monofocal phase plate for forming a third focus. The multifocal phase plate and the monofocal phase plate may be disposed on first and second base curvatures, respectively, that may have different radii of curvature. The ophthalmic lens may also have an intermediate phase plate located between the multifocal phase plate and the monofocal phase plate, the intermediate phase plate comprising a third plurality of echelettes disposed on a third base curvature having a third radius of curvature.

    Abstract translation: 用于提供多个焦点的眼科镜片具有包括前表面，后表面和光轴的光学元件。 光学元件具有第一区域和第二区域。 第一区域具有折射光焦度并且包括用于形成第一焦点和第二焦点的多焦点相位板。 第二区域具有折射光焦度并且包括用于形成第三焦点的单焦点相位板。 多焦点相位板和单焦点相位板可以分别设置在可以具有不同曲率半径的第一和第二基本曲率上。 眼用透镜还可以具有位于多焦点相位板和单焦点相位板之间的中间相位板，中间相位板包括设置在具有第三曲率半径的第三基底曲率上的第三多个小阶梯。

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