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1.发明公开公开(公告)号：US20240335324A1
公开(公告)日：2024-10-10
申请号：US18294321
申请日：2022-10-13
Applicant: APPASAMY ASSOCIATES PVT LTD
Inventor： Narayanasamy RAVILLA KASTHURI , Sri Rama Prasad JEYARAJ
CPC classification number: A61F9/0084 , A61B90/20 , A61F9/00834 , A61B2018/00601 , A61B2018/2025 , A61B2018/20355 , A61B2018/20553 , A61B2018/207 , A61F2009/0087
Abstract: The present invention relates to a single and/or dual laser delivery system attached to an existing ophthalmic operating microscope, comprising of a single and/or dual wavelength laser unit [1]; and a delivery system [5]. The laser unit [1] comprises of a green laser module 532 nm [3] and a yellow laser module 577 nm [4] along with an aiming beam [7] 635 nm. The delivery system comprises of a right-angle prism [5A]: X and Y Galvo assembly [5B] and a focusing lens assembly [5C]. The laser unit passes through a fiber optic cable [6] gets reflected using the right angle prism, gets deflected by the Galvo assembly, enters the focusing lens assembly and gets reflected by a folding mirror [5D] and focused on human eye capsule. The system converges and focuses the laser wavelengths in line with the aiming beam to create a circular pattern to accomplish a pre-measured Capsulorhexis.
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公开(公告)号：US11951043B2
公开(公告)日：2024-04-09
申请号：US17579915
申请日：2022-01-20
Applicant: Carl Zeiss Meditec AG
Inventor： Michael Bergt , Thomas Hamann , Robert Pomraenke
CPC classification number: A61F9/00834 , A61F9/00817 , A61F9/00821 , A61F9/00825 , A61F2009/00846 , A61F2009/0087 , A61F2009/00872 , A61F2009/00874 , A61F2009/00897
Abstract: A system for processing a portion in a processing volume of a transparent material by application of focused radiation including a device for generating and an optical system for focusing radiation, with a device for changing the position of the focus of the radiation and a control device. The system includes a controller that controls the ophthalmologic therapy system. The controller is encoded with a scan pattern. The scan pattern includes adjacent strokes with each adjacent stroke having an angle of inclination (α) to the beam axis; and the angle of inclination (α) of the strokes to the beam axis is always larger than or equal to the focal angle (φ) of the focused radiation.
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公开(公告)号：US11911104B2
公开(公告)日：2024-02-27
申请号：US16870808
申请日：2020-05-08
Applicant: AMO Development, LLC
Inventor： Javier Gonzalez
CPC classification number: A61B3/103 , A61B3/0025 , A61B3/10 , A61B3/107 , A61F9/00825 , A61F9/00827 , A61B3/102 , A61B3/1005 , A61F9/00834 , A61F2009/0087 , A61F2009/00851 , A61F2009/00872 , A61F2009/00882 , A61F2009/00887 , G01M11/0228 , G01N21/45
Abstract: A laser eye surgery system focuses light along a beam path to a focal point having a location within a lens of the eye. The refractive index of the lens is determined in response to the location. The lens comprises a surface adjacent a second material having a second refractive index. The beam path extends a distance from the surface to the focal point. The index is determined in response to the distances from the surface to the targeted focal point and from the surface to the actual focal point, which corresponds to a location of a peak intensity of an optical interference signal of the focused light within the lens. The determined refractive index is mapped to a region in the lens, and may be used to generate a gradient index profile of the lens to more accurately place laser beam pulses for incisions.
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公开(公告)号：US20230404805A1
公开(公告)日：2023-12-21
申请号：US18205320
申请日：2023-06-02
Applicant: Gholam A. Peyman
Inventor： Gholam A. Peyman
CPC classification number: A61F9/00812 , A61F2/1451 , A61F2/148 , A61F9/00804 , A61N5/062 , A61F9/00836 , A61F9/00834 , A61L27/3604 , A61L27/3666 , A61F2009/00872 , A61N2005/0661 , A61L2430/16 , A61F2240/004
Abstract: A tissue-augmented corneal inlay surgery technique is disclosed herein. In one embodiment, the surgery method includes the steps of: (i) implanting a corneal inlay into a recipient cornea of an eye of a patient; (ii) applying laser energy to a central portion of the corneal inlay and a portion of stromal tissue of the recipient cornea underneath the corneal inlay so as to modify the refractive power of the eye; (iii) applying a cross-linking solution that includes a photosensitizer to the recipient cornea of the eye of the patient; and (iv) irradiating the corneal inlay and surrounding corneal tissue so as to activate cross-linkers in the corneal inlay and the surrounding corneal tissue. In this embodiment, the central portion of the corneal inlay remains clear for the patient without being obstructed by swollen tissue so that the patient is able to see immediately after the corneal inlay surgery.
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5.发明公开公开(公告)号：US20230210654A1
公开(公告)日：2023-07-06
申请号：US18063961
申请日：2022-12-09
Applicant: AMO Groningen B.V.
Inventor： Robert Rosen , Franck Emmanuel Gounou , Carmen Canovas Vidal , Aixa Alarcon Heredia
CPC classification number: A61F2/1627 , A61F9/00834 , A61F2/1629
Abstract: Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL) that has a non-zero residual spherical error that requires an estimated diffractive power addition in the IOL. In some embodiments, a plurality of laser pulses are applied to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, the estimated diffractive power addition to correct for the residual spherical error.
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Patent Agency Ranking
公开(公告)号：US20230157812A1
公开(公告)日：2023-05-25
申请号：US18095748
申请日：2023-01-11
Applicant: University of Rochester
Inventor： Leonard Zheleznyak , Scott Catlin
CPC classification number: A61F2/1618 , G02B1/043 , A61F2/1451 , A61F2/1654 , A61F2/1613 , A61F2/1651 , A61F9/00806 , A61F9/00812 , A61F9/00829 , A61F9/00834 , A61F9/00838 , G02C7/049 , A61F9/00825 , A61F9/00827 , G02C7/041 , A61F2002/1696 , G02C7/048 , G02C2202/12 , G02C2202/24 , H01S3/2222
Abstract: Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or optical tissues is performed to address various types of vision correction.
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公开(公告)号：US20190247227A1
公开(公告)日：2019-08-15
申请号：US16246618
申请日：2019-01-14
Applicant: Gholam A. Peyman
Inventor： Gholam A. Peyman
CPC classification number: A61K9/0051 , A61F2/1451 , A61F9/0017 , A61F9/00781 , A61F9/0079 , A61F9/0081 , A61F9/00831 , A61F9/00834 , A61F2009/00872 , A61K9/0024 , A61K9/127 , A61K31/551 , A61K38/164 , A61K45/06 , A61L31/143 , A61L31/145 , A61L31/146
Abstract: Methods for treatment of dry eye and other acute or chronic inflammatory processes are disclosed herein. One method includes administering a drug delivery implant to a patient in need thereof, the drug delivery implant comprising one or more Rock inhibitors and/or one or more Wnt inhibitors, the patient having a medical condition selected from the group consisting of dry eye, lichen planus, arthritis, psoriasis, plantar fasciitis, pars planitis, scleritis, keratitis, chronic meibomian gland inflammation, optic nerve neuritis, uveitis, papillitis, diabetic neural pain, diabetic retinopathy, a cataract, a side effect occurring after refractive surgery, a side effect occurring after corneal transplant, a side effect occurring after retinal detachment surgery, and combinations thereof. The administration of the drug delivery implant to the patient treats the medical condition, reduces the symptoms associated with the medical condition, enhances nerve regeneration, and/or alleviates the medical condition.
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8.发明申请公开(公告)号：US20180231696A1
公开(公告)日：2018-08-16
申请号：US15946287
申请日：2018-04-05
Applicant: University of Rochester
Inventor： Wayne H. Knox , Dharmendra Jani , Li Ding
CPC classification number: G02B3/0087 , A61F2/1618 , A61F2/1627 , A61F9/00834 , A61L27/16 , A61L27/50 , A61L27/52 , A61L2400/18 , A61L2430/16 , G02B2003/0093 , G02C2202/12 , G02C2202/14 , C08L33/10
Abstract: A method for modifying the refractive index of an optical polymeric material. The method comprises continuously irradiating predetermined regions of an optical, polymeric material with femtosecond laser pulses to form a gradient index refractive structure within the material. The optical polymeric material can include a photosensitizer to increase the photoefficiency of the two-photo process resulting in the formation of the observed refractive structures. An optical device includes an optical, polymeric lens material having an anterior surface and posterior surface and an optical axis intersecting the surfaces and at least one laser-modified, GRIN layer disposed between the anterior surface and the posterior surface and arranged along a first axis 45° to 90° to the optical axis. The at least one laser-modified GRIN layer comprises a plurality of adjacent refractive segments characterized by a variation in index of refraction across at least one of at least a portion of the adjacent segments and along each segment.
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公开(公告)号：US20180177639A1
公开(公告)日：2018-06-28
申请号：US15901595
申请日：2018-02-21
Applicant: LensGen, Inc.
Inventor： Ramgopal Rao , Thomas Silvestrini
CPC classification number: A61F9/00812 , A61F2/16 , A61F2/1624 , A61F9/00834 , A61F9/00838 , A61F2009/0087 , A61F2009/00885 , A61F2009/00887 , A61F2250/0003
Abstract: A method for adjusting the refractive power of a fluid-filled intraocular lens implanted into a patient's eye. The method comprises selecting a pattern to cause a flattening of the intraocular lens or an increase in curvature of the intraocular lens, and ablating the pattern, onto either an optical element of the intraocular lens or a flexible element of the intraocular lens, to alter either one or both of a refractive power and an amplitude of accommodation of the intraocular lens. The ablating occurs while the intraocular lens remains implanted in the patient's eye. The ablating maintains the integrity of a fluid-filled interior cavity defined between the optical element and the flexible element, but causes the flattening of the intraocular lens or the increase in curvature of the intraocular lens.
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公开(公告)号：US20180110654A1
公开(公告)日：2018-04-26
申请号：US15553163
申请日：2016-02-23
Applicant: Carl Zeiss Meditec AG
Inventor： Michael Stefan Rill , Delbert Peter Andrews , Tobias Damm , Rupert Menapace
IPC: A61F9/008
CPC classification number: A61F9/00825 , A61F9/00834 , A61F9/00838 , A61F2009/0087 , A61F2009/00872 , A61F2009/00887 , A61F2009/00891 , A61F2009/00897
Abstract: An ophthalmological laser therapy device having a pulsed laser, a positioning system and a control system that produce incisions in a tissue of an eye, in particular for producing corneal access incisions and a corresponding method. The invention produces corneal access incisions having increased leak tightness under external influences. Compressive strength, and complex incision geometries can be realized. An ophthalmological laser therapy device has a control system which is programmed to vary the operating parameters of the laser system and/or of the positioning system on the basis of a local position of the focal volume of a laser beam in the corneal tissue such that the access incision in the corneal tissue is varied and/or interrupted in the width of the access incision. The invention further includes a corresponding computer program product and a method for performing a corneal access incision in a corneal tissue of an eye.
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